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28 results on '"Ciurea M"'

1. Point of care HbA1c level for diabetes mellitus management and its accuracy among tuberculosis patients: a study in four countries

Author

Huangfu, P., Laurence, Y.V., Alisjahbana, B., Ugarte-Gil, C., Riza, A.L., Walzl, G., Ruslami, R., Moore, D.A.J., Ioana, M., McAllister, S., Ronacher, K., Koesoemadinata, R.C., Grint, D., Kerry, S., Coronel, J., Malherbe, S.T., Griffiths, U., Dockrell, H.M., Hill, P.C., Crevel, R. van, Pearson, F., Critchley, J.A., Cliff, J.M., Eckold, C., Moore, D.A., Griffiths, U.K., Kerry, S.R., Anmontse, R., Netea, M.N., Ruesen, C., Lachmandas, E., Joosten, S.A., Ottenhoff, T.H.M., Vrieling, F., Haks, M.C., Kumar, V., Wijmenga, C., Kaufmann, S.H.E., Beigier, M., Golinski, R., Kleynhans, L., Smith, B., Stanley, K., Spuy, G.D. van der, Loxton, A.G., Chegou, N.N., Bosman, M., Thiart, L., Wagman, C., Tshivhula, H., Selamolela, M., Prins, N., Plessis, W.J. du, Rensburg, I.C. van, Toit, L. du, McAllister, S.M., Verrall, A.E., Cimpoeru, A., Ciocoiu, A., Dorobantu, S.C., Plesea, R.M., Popescu, E., Cucu, M.G., Streata, I., Burada, F., Serban-Sosoi, S., Nicoli, E.R., Panduru, M.N., Cioboata, R., Dudau, M.O., Nitu, F.M., Bazavan, I.C., Olteanu, M., Editoiu, C.D., Florescu, A., Ciontea, M.S., Capitanescu, I.D., Olaru, M., Tataru, T., Papurica, M.D., Valutanu, I., Dubreu, V., Stamatoiu, L., Enoiu, C., Mota, M., Popa, S., Firanescu, A.G., Popa, A., Gheonea, I.A., Bicuti, S., Lepadat, A., Streba, C., Demetrian, A.D., Ciurea, M., Vladu, I.M., Clenciu, D., Bicu, M.L., Lopez, S., Limascca, R., Villaizan, K., Castro, B., Flores, J., Solano, W., Soetedjo, N.N.M., Santoso, P., Chaidir, L., Susilawati, N., Annisa, J., Livia, R., Yunivita, V., Soeroto, A.Y., Permana, H., Imaculata, S., Gunawan, Y., Dewi, N.F., Apriani, L.A., and TANDEM Consortium

Subjects
endocrine system diseases, Epidemiology, diagnostic error, 0302 clinical medicine, middle aged, patient safety, DM, middle income country, 030212 general & internal medicine, hemoglobin A1c, Public health, Human immunodeficiency virus, adult, public health, anemia, female, Infectious Diseases, TB, priority journal, tuberculosis, diabetes mellitus, diagnostic accuracy, disease severity, epidemiology, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Tuberculosis, HbA1c, high performance liquid chromatography, Anemia, Point-of-care testing, prevalence, 030231 tropical medicine, purl.org/pe-repo/ocde/ford#3.03.08 [https], Article, 03 medical and health sciences, male, treatment refusal, Diabetes mellitus, Internal medicine, medicine, sex, human, infection risk, Point of care, point of care testing, hemoglobin blood level, business.industry, screening, nutritional and metabolic diseases, Likert scale, medicine.disease, major clinical study, body mass, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], age, purl.org/pe-repo/ocde/ford#3.02.07 [https], hyperglycemia, business, Body mass index
Abstract

Contains fulltext : 202938.pdf (Publisher’s version ) (Closed access) BACKGROUND: Diabetes mellitus (DM) is common among tuberculosis (TB) patients and often undiagnosed or poorly controlled. We compared point of care (POC) with laboratory glycated haemoglobin (HbA1c) testing among newly diagnosed TB patients to assess POC test accuracy, safety and acceptability in settings in which immediate access to DM services may be difficult. METHODS: We measured POC and accredited laboratory HbA1c (using high-performance liquid chromatography) in 1942 TB patients aged 18 years recruited from Peru, Romania, Indonesia and South Africa. We calculated overall agreement and individual variation (mean +/- 2 standard deviations) stratified by country, age, sex, body mass index (BMI), HbA1c level and comorbidities (anaemia, human immunodeficiency virus [HIV]). We used an error grid approach to identify disagreement that could raise significant concerns. RESULTS: Overall mean POC HbA1c values were modestly higher than laboratory HbA1c levels by 0.1% units (95%CI 0.1-0.2); however, there was a substantial discrepancy for those with severe anaemia (1.1% HbA1c, 95%CI 0.7-1.5). For 89.6% of 1942 patients, both values indicated the same DM status (no DM, HbA1c

Published
2019

2. Impact of Intermediate Hyperglycemia and Diabetes on Immune Dysfunction in Tuberculosis

Author

Eckold, C, Kumar, V, Weiner, J, Alisjahbana, B, Riza, A-L, Ronacher, K, Coronel, J, Kerry-Barnard, S, Malherbe, ST, Kleynhans, L, Stanley, K, Soeroto, A, Permana, H, Imaculata, S, Apriani, L, Ugarte-Gil, C, Walzl, G, van Crevel, R, Wijmenga, C, Critchley, JA, Dockrell, HM, Haks, M, Cliff, JM, Malherbe, S, Dockrell, H, Cliff, J, Moore, D, Griffiths, U, Laurence, Y, Aarnouste, R, Netea, M, Ruesen, C, Lachmandas, E, Kaufmann, S, Beigier, M, Golinski, R, Joosten, S, Ottenhoff, T, Vrieling, F, Smith, B, van der Spuy, G, Loxton, A, Chegou, N, Bosman, M, Thiart, L, Nitu, F, Wagman, C, Editoiu, C, Tshivhula, H, Selamolela, M, Prins, N, du Plessis, W, van Rensburg, I, du Toit, L, Critchley, J, Bazavan, I, Pearson, F, Grint, D, Florescu, A, McAllister, S, Hill, P, Verrall, A, Ioana, M, Riza, A, Cioboata, R, Dudau, M, Olteanu, M, Mota, M, Popa, SG, Firanescu, A, Popa, A, Gheonea, I, Bicuti, S, Lepadat, A, Capitanescu, I, Vladu, I, Papurica, M, Clenciu, D, Bicu, M, Streba, C, Demetrian, A, Ciurea, M, Cimpoeru, A, Ciocoiu, A, Dorobantu, S, Olaru, M, Plesea, R, Popescu, EL, Valutanu, I, Cucu, M, Streata, I, Burada, F, Serban-Sosoi, S, Panduru, N, Nicoli, E, Ciontea, M, Tataru, T, Dubreu, V, Stamatoiu, L, Lopez, S, Gunawan, Y, Limascca, R, Ruslami, R, Villaizan, K, Castro, B, Flores, J, Solano, W, Soetedjo, N, Santoso, P, Dewi, N, Chaidir, L, Koesoemadinata, R, Susilawati, N, Annisa, J, Livia, R, Yunivita, V, TANDEM (Concurrent Tuberculosis and Diabetes Mellitus, and unraveling the causal link, and improving care) Consortium

Subjects
0301 basic medicine, Microbiology (medical), Tuberculosis, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Inflammation, Transcriptome, 03 medical and health sciences, chemistry.chemical_compound, South Africa, 0302 clinical medicine, Immune system, Diabetes mellitus, Peru, Diabetes Mellitus, Medicine, Humans, 030212 general & internal medicine, Articles and Commentaries, Tuberculosis, Pulmonary, Whole blood, diabetes, business.industry, Mycobacterium tuberculosis, medicine.disease, Comorbidity, 3. Good health, 030104 developmental biology, Infectious Diseases, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], AcademicSubjects/MED00290, chemistry, tuberculosis, inflammation, Indonesia, Hyperglycemia, Immunology, hyperglycemia, Glycated hemoglobin, medicine.symptom, business
Abstract

Background People with diabetes have an increased risk of developing active tuberculosis (TB) and are more likely to have poor TB-treatment outcomes, which may impact on control of TB as the prevalence of diabetes is increasing worldwide. Blood transcriptomes are altered in patients with active TB relative to healthy individuals. The effects of diabetes and intermediate hyperglycemia (IH) on this transcriptomic signature were investigated to enhance understanding of immunological susceptibility in diabetes-TB comorbidity. Methods Whole blood samples were collected from active TB patients with diabetes (glycated hemoglobin [HbA1c] ≥6.5%) or IH (HbA1c = 5.7% to, Our study shows that people with diabetes and tuberculosis have altered peripheral immune profiles compared to people with only tuberculosis, and that these differences also exist in patients with intermediate hyperglycemia.

Published
2021

3. Stress-induced traps in multilayered structures

Author

Ciurea M., Lazanu S., Stavarache I., Lepadatu A., Iancu V., Mitroi M., Nigmatullin R., and Baleanu C.

Subjects
Condensed Matter::Quantum Gases
Abstract

The trap parameters of defects in Si/CaF 2 multilayered structures were determined from the analysis of optical charging spectroscopy measurements. Two kinds of maxima were observed. Some of them were rather broad, corresponding to "normal" traps, while the others, very sharp, were attributed to stress-induced traps. A procedure of optimal linear smoothing the noisy experimental data has been developed and applied. This procedure is based on finding the minimal value of the relative error with respect to the value of the smoothing window. In order to obtain a better accuracy for the description of the trapping-detrapping process, a Gaussian temperature dependence of the capture cross-sections characterizing the stress-induced traps was introduced. Both the normal and the stress-induced traps have been characterized, including some previously considered as only noise features. ©2011 American Institute of Physics.

Published
2011

4. Temperature dependence of capture coefficients in trapping phenomena

Author

Lepadatu A., Stavarache I., Lazanu S., Iancu V., Mitroi M., Nigmatulin R., and Ciurea M.

Subjects
Gaussian distribution, Capture coefficients, Relaxation currents, Traps
Abstract

The temperature dependence of the capture coefficients in trapping phenomena is investigated. It is proved that, besides the dependence induced by the thermal velocity of the carriers, the stress-induced traps at the interfaces of the multi-layered structures present a supplementary temperature dependence. This dependence is found to be of Gaussian type and is in a good agreement with the experimental results. © 2010 IEEE.

Published
2010

24. Role of MRI in the diagnosis and evaluation of cavernous hemangioma of the arm

Author

Ciurea, M. E., Bondari, S., Loredana Elena Stoica, and Gheonea, I. A.

Subjects
Case Presentation, Young Adult, Hemangioma, Cavernous, Angiography, Arm, angioCT, Humans, Female, Muscle, Skeletal, cavernous hemangioma, Magnetic Resonance Imaging, MRI
Abstract

Sinusoidal hemangioma is a rare type of cavernous hemangioma with different clinico-pathological aspects. They are usually localized in the extremities with interest in the subcutaneous layer. The new imaging techniques play an important role in diagnosis, evaluation and follow-up of these types of tumors. We describe the case of a 21-year-old patient, four times operated for a recurrent soft tissue tumor, located intramuscularly in the distal third of the upper limb. Plain X-ray and computer tomography (CT) showed a nonspecific mass with calcification. The MRI (magnetic resonance imaging) exam demonstrated a lobulated heterogeneous signal tumor mass in the biceps brachial muscles, with high signal intensity on T2 weighted images and intermediate signal on T1 weighted images. MRI accurately assessed the extent of the tumor and evaluated the recurrence. MRI imagings combined with contrast-enhanced sequences were used to classify the lesions in low flow vascular disorders. CT angiography with multiplanar reconstructions (MPR), maximum intensity projections (MIP) and volume-rendered reconstructions (VR) was useful in confirming the venous origin of the tumor.

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