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13 results on '"Christopher Sean Straub"'

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1. Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

2. 'Addition' and 'Subtraction': Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors

3. Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight

4. Targeting IAPs as An Approach to Anti-Cancer Therapy

5. A Facile Preparation of an Octahydropyrrolo[2,3-c]pyridine Enantiomer

6. Development of Peptidomimetics Targeting IAPs

7. Smac mimetics: implications for enhancement of targeted therapies in leukemia

8. A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling

9. Abstract LB-139: IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism

10. Abstract B159: Heterozygous IDH1 mutations modify the citric acid (TCA) cycle metabolism and sensitize cells to inhibition of mitochondrial respiration/oxidative phosphorylation

11. Abstract C54: Aryl-N-(1H-imidazol-2-yl)-acetamides: Nonpeptidic binders of Bir3 cIAP protein

12. Abstract 138: Therapeutic targeting of inhibitor of apoptosis proteins

13. Abstract B27: Correlation between TNFα and LCL161 anti-tumor activity in patient derived xenograft models of human cancer

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