1. Liposome-trapped penicillins in growth inhibition of some penicillin-resistant bacteria
- Author
-
Chowdhury Mk, Parul Chakrabarti, and R. Goswami
- Subjects
Staphylococcus aureus ,Penicillin Resistance ,Bacillus ,Penicillins ,medicine.disease_cause ,Applied Microbiology and Biotechnology ,Microbiology ,chemistry.chemical_compound ,Methicillin ,medicine ,Escherichia coli ,Bacillus licheniformis ,Penicillin resistant ,Liposome ,biology ,Penicillin G ,biology.organism_classification ,Penicillin ,chemistry ,Liposomes ,Growth inhibition ,Cloxacillin ,Bacteria ,medicine.drug - Abstract
Liposome-trapped penicillin causes growth inhibition of penicillin-resistant Staphylococcus aureus (meta 18), Bacillus licheniformis (749/C) and Escherichia coli. Liposome has been prepared from the positively charged, negatively charged and polar lipids of respective organisms. Positively charged liposome containing penicillin causes 77% growth inhibition in the case of Staph. aureus (meta 18) and 61% in the case of Esch. coli. In the case of B. licheniformis (749/C), 40–43% growth inhibition has been observed with liposome-entrapped penicillin. Homology, composition and charge of liposomes do not seem to have significant effect in percentage inhibition of this organism.
- Published
- 1981