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5 results on '"Cheng, Zhenshun"'

1. Additional file 4 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Author

Xia, Jingen, Gu, Sichao, Lei, Wei, Zhang, Jihua, Wei, Hui, Liu, Chao, Zhang, Han, Lu, Rongli, Zhang, Liqiong, Jiang, Mingyan, Hu, Chao, Cheng, Zhenshun, Wei, Chaojie, Chen, Yusheng, Lu, Fengfeng, Chen, Min, Bi, Hong, Liu, Hui, Yan, Cunzi, Teng, Hong, Yang, Yang, Liang, Chen, Ge, Yanlei, Hou, Pengguo, Liu, Jialin, Gao, Weiwei, Zhang, Yi, Feng, Yingying, Tao, Cheng, Huang, Xu, Pan, Pinhua, Luo, Hong, Yun, Chunmei, and Zhan, Qingyuan

Abstract

Additional file 4. Figure S1: Kaplan-Meier analysis of time since intervention to readmission during 90 days follow-up period. The cumulative incidence function and Gray’s test were used to consider deaths as competing events to evaluate the difference of time to readmission for acute exacerbation between two groups.

Published
2022
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2. Additional file 1 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Author

Xia, Jingen, Gu, Sichao, Lei, Wei, Zhang, Jihua, Wei, Hui, Liu, Chao, Zhang, Han, Lu, Rongli, Zhang, Liqiong, Jiang, Mingyan, Hu, Chao, Cheng, Zhenshun, Wei, Chaojie, Chen, Yusheng, Lu, Fengfeng, Chen, Min, Bi, Hong, Liu, Hui, Yan, Cunzi, Teng, Hong, Yang, Yang, Liang, Chen, Ge, Yanlei, Hou, Pengguo, Liu, Jialin, Gao, Weiwei, Zhang, Yi, Feng, Yingying, Tao, Cheng, Huang, Xu, Pan, Pinhua, Luo, Hong, Yun, Chunmei, and Zhan, Qingyuan

Subjects
respiratory system, human activities, humanities
Abstract

Additional file 1. Table S1: Settings of treatment, vital sign, Borg scores, airway dryness score and blood gas analysis between the conventional oxygen therapy group and the high-flow nasal cannula group within 72 hours after randomization.

Published
2022
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3. Additional file 2 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Author

Xia, Jingen, Gu, Sichao, Lei, Wei, Zhang, Jihua, Wei, Hui, Liu, Chao, Zhang, Han, Lu, Rongli, Zhang, Liqiong, Jiang, Mingyan, Hu, Chao, Cheng, Zhenshun, Wei, Chaojie, Chen, Yusheng, Lu, Fengfeng, Chen, Min, Bi, Hong, Liu, Hui, Yan, Cunzi, Teng, Hong, Yang, Yang, Liang, Chen, Ge, Yanlei, Hou, Pengguo, Liu, Jialin, Gao, Weiwei, Zhang, Yi, Feng, Yingying, Tao, Cheng, Huang, Xu, Pan, Pinhua, Luo, Hong, Yun, Chunmei, and Zhan, Qingyuan

Abstract

Additional file 2. Table S2: Comparison of daily duration of treatment with 7days after randomization, the time of treatment failure and noninvasive positive pressure ventilation start between the conventional oxygen therapy group and the high-flow nasal cannula group.

Published
2022
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4. Additional file 3 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Author

Xia, Jingen, Gu, Sichao, Lei, Wei, Zhang, Jihua, Wei, Hui, Liu, Chao, Zhang, Han, Lu, Rongli, Zhang, Liqiong, Jiang, Mingyan, Hu, Chao, Cheng, Zhenshun, Wei, Chaojie, Chen, Yusheng, Lu, Fengfeng, Chen, Min, Bi, Hong, Liu, Hui, Yan, Cunzi, Teng, Hong, Yang, Yang, Liang, Chen, Ge, Yanlei, Hou, Pengguo, Liu, Jialin, Gao, Weiwei, Zhang, Yi, Feng, Yingying, Tao, Cheng, Huang, Xu, Pan, Pinhua, Luo, Hong, Yun, Chunmei, and Zhan, Qingyuan

Abstract

Additional file 3. Table S3: The comparison of age, gender, oxygenation and blood gas parameters on admission between the enrolled patients and the declined patients.

Published
2022
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5. [Transforming growth factor-β1 induces epithelial-mesenchymal transition in A549 cells by up-regulating expression of calpain]

Author

Tan, Weijun, Cheng, Zhenshun, Tan, Qiuyue, Wang, Ting, Lian, Min, and Zhang, Li

Subjects
Transcriptional Activation, Transforming Growth Factor beta1, Epithelial-Mesenchymal Transition, Acrylates, Gene Expression Regulation, Antigens, CD, Calpain, Transforming Growth Factors, Humans, Epithelial Cells, Cadherins, Actins, Cell Line
Abstract

To investigate the effect of transforming growth factor-β1 (TGF-β1) on epithelial-mesenchymal transition in type II alveolar epithelial cells and the relationship with Calpain.The type II alveolar epithelial cell line-A549 cells cultured in vitro were divided into 4 groups: the control group, the TGF-βl group, the TGF-β1 + PD150606 group, the PD150606 group. Given the corresponding processing,Western-blot and RT-PCR were utilized to evaluate the expression of Calpain- 1,E-cad and α-SMA.Compared with the control group, the protein and mRNA expression of Calpain-1 and α-SMA in the TGF-β1 group was markedly increased, but the protein and mRNA expression of E-cad was significantly decreased. While, after calpain inhibitor PD150606 was added, the protein and mRNA expression of Calpain-1 and α-SMA was markedly decreased and the protein and mRNA expression of E-cad was significantly increased in the TGF-βl + PD150606 group, but there was no difference between TGF-β1 + PD150606 group and control group. But with Calpain inhibitor PD150606 alone, the expression of Calpain-1,E-cad and α-SMA was no difference with the control group.TGF-βl could induce epithelial-mesenchymal transition in A549 cells by up-regulating expression of calpain which could be inhibited by calpain inhibitor PD150606.

Published
2015

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