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1. Evaluation of PVA biodegradable electric conductive membranes for nerve regeneration in axonotmesis injuries: the rat sciatic nerve animal model

Author

Ribeiro, Jorge, Caseiro, Ana Rita, Pereira, Tiago, Armada da Silva, Paulo Alexandre, Pires, Isabel, Prada, Justina, Amorim, Irina, Leal Reis, Inês, Amado, Sandra, Santos, José Domingos, Bompasso, Simone, Raimondo, Stefania, Varejão, Artur Severo Proença, Geuna, Stefano, Luís, Ana Lúcia, and Maurício, Ana Colette

Subjects
Male, carbon nanotubes, morphometric analysis, axonotmesis, functional analysis, nerve regeneration, nerve-guides, neurogenic atrophy, polypyrrole, polyvinyl alcohol, Ceramics and Composites, Biomaterials, Biomedical Engineering, 2506, Membranes, Artificial, Sciatic Nerve, Nerve Regeneration, Rats, Rats, Sprague-Dawley, Polyvinyl Alcohol, Absorbable Implants, Animals
Abstract

The therapeutic effect of three polyvinyl alcohol (PVA) membranes loaded with electrically conductive materials - carbon nanotubes (PVA-CNTs) and polypyrrole (PVA-PPy) - were tested in vivo for neuro-muscular regeneration after an axonotmesis injury in the rat sciatic nerve. The membranes electrical conductivity measured was 1.5 ± 0.5 × 10

Published
2016

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