Schmidt, Stefanie, Riel, Ricard, Frances, Albert, Lorente Garín, José Antonio, Bonfill Cosp, Xavier, Martinez Zapata, María José, Morales Suárez-Varela, María, De la Cruz, Javier, Emparanza, José Ignacio, Sánchez-Pérez, María José, Zamora, Javier, Ramos Goñi, Juan Manuel, Alonso, Jordi, Ferrer, Montserrat, Becerra, Virginia, Pardo Cladellas, Yolanda, Garin, Olatz, Orrego Villagran, Carola, Suñol, Rosa, Osorio, Dimelza, Canovas, Esther, Sancho Pardo, Gemma, Bolívar, Ignasi, Bachs, Jordi, Maroto, Pablo, Quintana, María Jesús, Martín Lorente, Cristina, Algaba, Ferran, Palou Redorta, Joan, Esquena Fernández, Salvador, Puigvert, Fundació, Vernooij, Robin W.M., Martínez, Arnaia, Pijoan Zubizarreta, J. I., Martínez, Lorea, Castro Diaz, D. M., Bastida, J. L., Suárez Pacheco, Armando, López, C. G., Cozar Olmo, J. M, Martínez, Carmen, Chan, Daisy Chang, Sanchez Perez, M. J., Díaz Moratinos, A. I., Luis, A. M., Hervás, A., Ocaña, C. V., Varona, C., Burgos, Javier, Polo Rubio, J. A., López-Fando Lavalle, L., Jimenez Cidre, M. A., Garcia, A. M., Farras, N. P., Lopez, R. M., Garcia, S. S., Abraira, Víctor, Dos Santos, V. G., De la Cámara, A. G., Martinez, J. P., Muñoz, H. G., Cabeza Rodríguez, M. A., Díaz, I. R., Sanz Jaka, J. P., Velásquez, M. J., González, A. L., Morales, M., Camps, Carlos, Díaz, C. C., Vidal, E. M., Ballester, F. S., Juan Escudero, J. U., Peidro, J. P., Torrecilla, J. L., Ramos Campos, M. M., Cebollada, M. M., EMPARO-CU Study Group, [Schmidt,S, Alonso,J, Ferrer,M] Health Services Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. [Schmidt,S, Alonso,J] Department of Experimental and Health Sciences, Universidad Pompeu Fabra (UPF), Barcelona, Spain. [Schmidt,S, Bonfill,X, Martinez-Zapata,MJ, Morales Suarez-Varela,M, dela Cruz,J, Emparanza,JI, Sánchez,MJ, Zamora,J, Ferrer,M] CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. [Riel,R] Center of Primary Health Care El Clot, Barcelona, Spain. [Frances,A, Lorente Garin,JA] Department of Urology, Hospital del Mar, Barcelona, Spain. [Bonfill,X, Martinez-Zapata,MJ] Iberoamerican Cochrane Centre, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain. [ Bonfill,X, Ferrer,M] Universitat Autònoma de Barcelona (UAB), Barcelona, Spain. [Morales Suarez-Varela,M] Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia, Valencia, Spain. [Morales Suarez-Varela,M] Center for Public Health Research (CSISP), Valencia, Spain. [dela Cruz,J] Hospital 12 de Octubre, Madrid, Spain. [Emparanza,JI] Clinical Epidemiology Unit, Hospital Universitario Donostia, BioDonostia, San Sebastian, Spain. [Sánchez,MJ] Escuela Andaluza de Salud Pública, Granada, Spain. [Sánchez,MJ] Instituto de Investigación Biosanitaria de Granada, Granada, Spain. [Zamora,J] Clinical Biostatistics Unit, Hospital Ramón y Cajal (IRYCIS), Madrid, Spain. [Ramos Goñi,JM HTA Unit of the Canary Islands Health Service (SESCS), Tenerife, Spain. [Ramos Goñi,JM] Health Services Research on Chronic Patients Network (REDISSEC), Bilbao, Spain., This work was supported by grants from Instituto de Salud Carlos III FEDER (PS09/02139, PS09/01204, PS09/01619, PS09/02555, PI12/00772) and from AGAUR (2012FI_B1 00177, and 2009 SGR 1095).