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A granular multiphase model has been used to evaluate the action of differently sized particles on the dynamics of fountains and associated pyroclastic density currents. The model takes into account the overall disequilibrium conditions between a gas phase and several solid phases, each characterized by its own physical properties. The dynamics of the granular flows has been simulated by adopting a Reynolds Average Navier-Stokes model for describing the turbulence effects. Numerical simulations have been carried out by using different values for the eruptive column temperature at the vent, solid particles frictional concentration, turbulent kinetic energy, and dissipation. The results obtained underline the importance of the multiphase nature of the model and characterize several disequilibrium effects. The low concentration (≤ 5 · 10–4) sectors lie in the upper part of the granular flow, above the fountain, and above the pyroclastic current tail and body as thermal plumes. The high concentration sectors, on the contrary, form the fountain and remain along the ground of the granular flow. Hence, pyroclastic density currents are assimilated to granular flows constituted by a low concentration suspension flowing above a high concentration basal layer (boundary layer), from the proximal regions to the distal ones. Interactions among solid, differently sized particles in the boundary layer of the granular flow are controlled by collisions between particles, whereas particles dispersal in the suspension is determined by the dragging of the gas phase. The simulations describe well the dynamics of a tractive boundary layer leading to the formation of stratified facies during eruptions having a different magnitude.

Communication systems comprising several local area networks (LANs) interconnected by bridges are modeled with Generalized Stochastic Petri Nets (GSPNs). GSPN models are developed at different levels of detail, progressively abstracting from the detailed behavior of real systems, and exploiting symmetries present in simple interconnected LAN topologies by “folding” the detailed GSPN models. The numerical results obtained from the solution of GSPN models are validated against results of very detailed simulation experiments, and found in good agreement, even for the most abstract GSPN models. Advantages and drawbacks of the GSPN modeling approach are discussed at the end of the paper.

The authors have reviewed the symptom hematuria in childhood, suggesting a simple flow chart for ambulatorial pediatricians.

Sudden death is a possible occurrence for newborns younger than 1 year with severe aortic coarctation (CoA) before surgical correction. In our previous study, we showed a significant increase of QTc-D and JTc-D in newborns with isolated severe aortic coarctation, electrocardiographic parameters that clinical and experimental studies have suggested could reflect the physiological variability of regional and ventricular repolarization and could provide a substrate for life-threatening ventricular arrhythmias. The aim of the current study was to evaluate the effect of surgical repair of CoA on QTc-d, JTc-d in severe aortic coarctation newborns with no associated congenital cardiac malformations. The study included 30 newborns (18M; 70±12 h old) affected by severe congenital aortic coarctation, without associated cardiac malformations. All newborns underwent to classic extended end-to-end repair. Echocardiographic and electrocardiographic measurements were performed in each patient 24 h before and 24 h after the interventional procedure and at the end of the follow-up period, 1 month after the surgical correction. All patients at baseline, 24 h and one month after CoA surgical repair did not significantly differ in terms of heart rate, weight, height, and echocardiographic parameters. There were no statistically significant differences in QTc-D (111.7±47.4 vs 111.9±63.8 ms vs 108.5±55.4 ms; P=0.4) and JTc-D (98.1±41.3 vs 111.4±47.5 vs 105.1±33.4 ms; P=0.3) before, 24 h and 1 month after CoA surgical correction. In conclusions, our study did not show a statistically significant decrease in QTc-D and JTc-D, suggesting the hypothesis that the acute left ventricular afterload reduction, related to successful CoA surgical correction, may not reduce the ventricular electrical instability in the short-term follow-up.