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4 results on '"Brogliatti, B"'

1. An internal medicine perspective review of risk factors for assessing and progression of primary open angle glaucoma

Author

Alessandro Guido Actis, Dall Orto, L., Penna, R., Brogliatti, B., and Rolle, T.

Subjects
Diabetes Complications, Sleep Apnea Syndromes, Hypothyroidism, Adrenal Cortex Hormones, Risk Factors, Hypertension, Disease Progression, Internal Medicine, Humans, Ocular Hypertension, Hyperthyroidism, Glaucoma, Open-Angle, Intraocular Pressure
Abstract

Aim of this review was to resume risk factors for the assess and progression of primary open-angle glaucoma (POAG), particularly considering systemic risk factors that can be associated with glaucomatous damage. If intraocular pressure is the main risk factor, we must consider carefully familiarity, age, gender and possible associations with diabetes, hypertension, vascular autoregulation disorders, hypo- and hyperthyroidism, hypo- and hyperadrenalism, sleep apnea syndrome, corticosteroids therapies and other suspected factors cited in literature. Glaucoma's etiology remains unknown, its physiopathology is poorly understood and its diagnosis is often difficult. It is the leading cause of irreversible blindness worldwide and it is the real "silent thief of sight" because the loss of vision often occurs gradually over a long period of time, and symptoms only occur when the disease is quite advanced. Cost-effectiveness analyses for POAG screening are weighted by the degree of uncertainty that glaucoma screening can be effective and reliable achieved. Addressing patients to an ophthalmologic investigation on the basis of the identified risk factors is a fundamental preventing measure.

Published
2013

3. A 1-year study to compare the efficacy and safety of once-daily travoprost 0.004%/timolol 0.5% to once-daily latanoprost 0.005%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension

Author

Topouzis, F., Melamed, S., Danesh-Meyer, H., Wells, A. P., Kozobolis, V., Wieland, H., Andrew, R., Wells, D., Kozobolis, V. P., Maskaleris, G., Detorakis, E., Anastasopoulos, E., Pappas, T., Kandarakis, A., Koutroumanos, J., Aspiotis, M., Pappa, C., Vaikoussis, E., Paschalidis, T., Bournas, P., Kazatzis, N., Goldberg, I., Stuart Graham, Healey, P., Rait, J. L., Bank, A., Healey, P. R., Crowston, J., Guzowski, M., Covar, R., Lee, A., Jen-Wan, Azar, D., Stadion, P., Lizin, F., Groot, V., Schraepen, P., Reyntjens, B., Kestelyn-Stevens, A. -M, Witters, F., Teesalu, P., Kuus, I., Oll, M., Aamer, U., Alas, E., Pastak, M., Delbosc, B. Y. C., Gerstenberger, A., Jungmann, P., Hamacher, L. T., Hellmair, U., Bayer, A. U. M., Foerster, W., Christ, T., Reibaldi, A., Uva, M., Longo, A., Lombardo, D., Trimarchi, F., Milano, G., Clemente, A., Rossi, M. G., Scatassi, I., Montemurro, F., Grignolo, F. M., Brogliatti, B., Rolle, T., Favero, C., Giacosa, E., Fornero, A., Goldenfeld, M., Verbin, H., Vilner, Z., Knaan, R., Moroz, I., Geyer, O., Segev, E., Kurtz, S., Neudorfer, M., Shemesh, G., Zayit, S., Volksone, L., Karlsone, L., Laganovska, G., Baumane, K., Egite, I., Januleviciene, I., Kuzmiene, L., Riley, A., Bedggood, A., Long, H., Ashraff, N., Abrantes, P. A. L., Reina, M., Silva, J. P., Ilharco, J., Chew, P. T. K., Thean, L., Lim, B. A., Manuel, J., Loon, S. C., Tan, C., Yeong, S. M., Seah, S. K. L., Oen, F., Husain, R., Hoh, S. T., Tin, A., Sánchez, J. G., Feijoo, J. G., La Casa, J. M. M., Gómez, A. C., López, F. M. H., Llorens, V. P., Júlvez, L. P., Martínez, M. L. G., Póvez, J. M. L., Arias-Puente, A., Carrasco, C., Del Carmen, M., García, Y., Alba, A., Gurdiel, E., Dorronzoro, E., Muniesa, M. J., Lu, D. -W, Clearkin, L. G., and Patwala, Y.

4. Intraocular pressure and progression of visual field damage

Author

Brogliatti, B., Rigault, R., Palanza, L., Savio, E., Rolle, T., Antonio Maria Fea, and Boggio Merlo, S.

Subjects
Tonometry, Ocular, Disease Progression, Vision Disorders, Humans, Visual Fields, Glaucoma, Open-Angle, Intraocular Pressure, Retrospective Studies
Abstract

Contradicting results concerning IOP control and visual field deterioration are presented. Some of these inconsistencies may be due to the statistical method of analysis. Sixty POAG patients with a perimetric follow-up over 3 years were selected. Mean and maximum IOPs were considered during the same period. The patients were divided into two groups according to the IOP control (well controlled or poorly controlled). Visual field progression was defined as a reduction in sensitivity over the fifth percentile in more than four points. Mean IOPs were not significantly different in the group of patients with a visual field deterioration compared to the stable ones, but the percentage of patients with a visual field deterioration was significantly higher in patients with higher IOPs. This holds especially true if IOP below 16 mmHg (G) is considered the 'target pressure'. IOP reduction seems to play an essential role in visual field progression. In glaucomatous patients, a strict (16 mmHg (G)) might be necessary.

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