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Your search keyword '"Bortone, Alessandro Santo"' showing total 2 results
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2 results on '"Bortone, Alessandro Santo"'

1. Symptoms, disease severity and treatment of adults with a new diagnosis of severe aortic stenosis

Author

Frey, Norbert, Steeds, Richard Paul, Rudolph, Tanja K., Thambyrajah, Jeetendra, Serra, Antonio, Schulz, Eberhard, Maly, Jiri, Aiello, Marco, Lloyd, Guy, Bortone, Alessandro Santo, Hauptmann, Karl Eugen, Clerici, Alberto, Delle Karth, Georg, Rieber, Johannes, Indorfi, Ciro, Mancone, Massimo, Belle, Loic, Lauten, Alexander, Arnold, Martin, Bouma, Berto J., Lutz, Matthias, Pohlmann, Christiane, Kurucova, Jana, Thoenes, Martin, Bramlage, Peter, Messika-Zeitoun, David, Cardiology, ACS - Heart failure & arrhythmias, and ACS - Pulmonary hypertension & thrombosis

Subjects
Male, Comorbidity, Risk Assessment, Severity of Illness Index, Ventricular Function, Left, aortic stenosis, surgical aortic valve replacement, symptoms, transcatheter aortic valve replacement, age factors, aged, aged, 80 and over, aortic valve, aortic valve stenosis, asymptomatic diseases, comorbidity, cross-sectional studies, europe, female, hemodynamics, humans, male, predictive value of tests, prognosis, prospective studies, registries, risk assessment, risk factors, severity of illness index, ventricular function, left, echocardiography, left, Predictive Value of Tests, Risk Factors, 80 and over, Humans, Prospective Studies, Registries, Aged, Aged, 80 and over, Age Factors, Hemodynamics, Aortic Valve Stenosis, Prognosis, Europe, Cross-Sectional Studies, Echocardiography, Aortic Valve, Asymptomatic Diseases, ventricular function, Female
Abstract

Objective Contemporary data on patients with previously undiagnosed severe aortic stenosis (AS) are scarce. We aimed to address this gap by gathering data from consecutive patients diagnosed with severe AS on echocardiography. Methods This was a prospective, multicentre, multinational, registry in 23 tertiary care hospitals across 9 European countries. Patients with a diagnosis of severe AS were included using echocardiography (aortic valve area (AVA) 4 m/s and/or mean transvalvular gradient >40 mm Hg). Results The 2171 participants had a mean age of 77.9 years and 48.0% were female. The mean AVA was 0.73 cm 2, V max 4.3 m/s and mean gradient 47.1 mm Hg; 62.1% had left ventricular hypertrophy and 27.3% an ejection fraction (EF)

Published
2019

2. Prosthesis depth and conduction disturbances after last generation balloon-expandable transcatheter aortic valve implantation

Author

Eugenio Stabile, Alessandro Santo Bortone, Luigi Salemme, Mariangela Cicala, Sebastiano Verdoliva, Gaetano Contegiacomo, Fortunato Iacovelli, Maria Angela Losi, Tullio Tesorio, Antonio Pignatelli, Armando Pucciarelli, Angelo Cioppa, Giovanni Esposito, Grigore Popusoi, Enrico Coscioni, Giuseppe Giugliano, Iacovelli, Fortunato, Pignatelli, Antonio, Giugliano, Giuseppe, Stabile, Eugenio, Cicala, Mariangela, Salemme, Luigi, Cioppa, Angelo, Popusoi, Grigore, Pucciarelli, Armando, Verdoliva, Sebastiano, Bortone, Alessandro Santo, Losi, MARIA ANGELA, Coscioni, Enrico, Esposito, Giovanni, Contegiacomo, Gaetano, and Tesorio, Tullio

Subjects
Male, Pacemaker, Artificial, Aortic stenosi, Time Factors, medicine.medical_treatment, Action Potentials, 030204 cardiovascular system & hematology, Prosthesis, Electrocardiography, 0302 clinical medicine, Heart Rate, Risk Factors, Odds Ratio, Ventricular outflow tract, Fluoroscopy, 030212 general & internal medicine, Aged, 80 and over, medicine.diagnostic_test, Cardiac Pacing, Artificial, Balloon expandable stent, Treatment Outcome, Italy, Aortic Valve, Heart Valve Prosthesis, Cardiology, Female, Cardiology and Cardiovascular Medicine, Atrioventricular block, Balloon Valvuloplasty, medicine.medical_specialty, Transcatheter aortic, Prosthesis Design, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, Physiology (medical), Internal medicine, medicine, Humans, Aged, Pacemaker implantation, Conduction abnormalities, Chi-Square Distribution, business.industry, Arrhythmias, Cardiac, Aortic Valve Stenosis, medicine.disease, Logistic Models, Multivariate Analysis, Linear Models, Permanent pacemaker, business
Abstract

Aims Preliminary data on Sapien 3 valve (S3-THV) use for transcatheter aortic valve implantation have shown an increased permanent pacemaker implantation (PPMI) rate with respect to Sapien XT valve. Aim of this study was to investigate the role of S3-THV position in the left ventricular outflow tract (LVOT) on electrocardiographic changes suggestive of atrioventricular (ΔPR) and/or intraventricular (ΔQRS) conduction abnormalities and 30 days PPMI rate. Methods and results Eighty-six consecutive patients treated with S3-THV were included in the study. All patients underwent clinical and electrocardiogram evaluation. Left ventricular outflow tract prosthesis depth was assessed by fluoroscopy and expressed quantitatively (mm) and as aorto-ventricular ratio (AVR). Eight patients (9.3%) needed PPMI at 30 days. A low AVR (≤60/40) predicted PPMI (OR = 6.09, 95% CI 1.19–31.01, P = 0.030) and resulted into higher PPMI rate, compared with higher AVR (30.0 vs. 6.6%, P = 0.017). For each millimetre increase in the LVOT prosthesis depth PPMI risk increased by 1.41 times (95% CI 1.06–1.87, P = 0.017). In patients with low AVR, ΔPR was higher than in those with higher AVR (33.4 ± 56.7 vs. 12.1 ± 19.4 ms, P = 0.021) and ΔPR was associated to LVOT prosthesis depth ( β = 0.286, P = 0.009). Furthermore, ΔPR was associated with risk of PPMI (OR = 1.03, 95% CI 1.01–1.06, P = 0.024). Conclusions A low AVR is associated to higher ΔPR and PPMI rates. The correlation between LVOT prosthesis depth with ΔPR and higher PPMI rate suggests the need of a careful S3-THV implantation.

Published
2016

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