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Background and objectives The appearance of a highly contagious disease forced the confinement of the population in almost all parts of the world, causing an increase in psychological problems, with pregnant women being a particularly vulnerable group to suffer negative consequences. The aim of this research was to check which confinement or psychological stress variables are related to the increase of anxious and depressive symptoms in pregnant women, as a consequence of the pandemic caused by the COVID-19. Materials and methods The sample was composed of 131 pregnant women who experienced the confinement imposed by the Government of Spain on March 14, 2020. Sociodemographic, obstetric, confinement related and psychological variables were collected. Results Perceived stress, pregnancy-specific stress, as well as insomnia are predictive variables in most anxious (obsessions and compulsions, anxiety and phobic anxiety) and depressive symptoms related to COVID-19. Conclusions It is important to focus future psychological interventions in this population on stress control and sleep monitoring, since these variables influence the increase of anxiety and depression.

Antecedentes y objetivos La aparición de una enfermedad altamente contagiosa obligó a confinar a la población en casi todo el mundo, ocasionando el aumento de problemática psicológica, siendo las mujeres embarazadas un grupo especialmente vulnerable a sufrir consecuencias negativas. El objetivo de esta investigación fue comprobar qué variables de confinamiento o estrés psicológico están relacionadas con el aumento de la sintomatología ansiosa y depresiva en mujeres embarazadas, como consecuencia de la pandemia ocasionada por la COVID-19. Materiales y métodos La muestra estuvo compuesta por 131 mujeres embarazadas que vivieron el confinamiento impuesto por el Gobierno de España el 14 de marzo de 2020. Se recogieron variables sociodemográficas, obstétricas, relacionadas con el confinamiento y variables psicológicas. Resultados El estrés percibido, estrés específico del embarazo, así como el insomnio son variables predictoras en la mayoría de síntomas ansiosos (obsesiones y compulsiones, ansiedad y ansiedad fóbica) y depresivos relacionados con la COVID-19. Conclusiones Es importante destinar futuras intervenciones psicológicas en esta población al control del estrés y monitorización del sueño, ya que estas variables influyen en el incremento de ansiedad y depresión.

Due to an absence of maternal stress being measured in routine prenatal care by clinicians, prenatal stress has become a serious problem which is associated with poorer obstetric outcomes, as well as worse maternal and infant health. For that reason, the aim of this study was the translation, validation and adaptation of Prenatal Distress Questionnaire Revised (NuPDQ) in a Spanish sample.Three-hundred and seventy-one pregnant women were assessed using the NuPDQ, the Prenatal Distress Questionnaire, Perceived Stress Scale and the Connor-Davidson Resilience Scale. The NuPDQ was translated into Spanish by the backtranslation method and administered to participants.A confirmatory factor analysis revealed the established unidimensional structure to be a poor fit to data with the Spanish version. An exploratory factor analysis suggested a five-factor structure with 14 items. The instrument had good reliability, convergent and discriminant validity psychometric properties.The five-factor 14-item NuPDQ is useful to assess pregnancy-specific stress in Spanish pregnant women. It may be appropriate to use this instrument in order to identify pregnant women with high pregnancy-specific stress to try to prevent negative consequences derived from those high levels.

Pregnancy is a life process that brings about a series of associated changes, both physical and psychological, in women. The psychopathological changes occurring in pregnant women due to the simple fact of this new vital stage are unknown. Therefore, the objective of this study was to compare the psychopathological symptoms present during pregnancy with those present in non-pregnant women, as well as the perceived stress and hair cortisol levels. For this, a group of non-pregnant women (n = 171) were compared with pregnant women who were in the first trimester (n = 124), second trimester (n = 200) and third trimester (n = 190). Moreover, 77 women were followed up to verify their psychopathological course of pregnancy. Differences were found between pregnant and non-pregnant women relating to a wide range of psychopathological symptoms, perceived stress and hair cortisol levels. The symptoms were greater in the group of pregnant women. By studying different types of psychopathological symptoms associated with pregnancy, it is possible to assign psychological interventions to given characteristics of pregnant women. In addition, we can broaden our knowledge about the psychological aspects of pregnancy and the changes associated with it.

Optimal adaptation to changes that occur during pregnancy is essential to prevent possible negative effects on maternal psychological health (such as stress or postpartum depression). In fact, an adequate adaptation to the new life situation has implications on the subsequent offspring´s development. Thus, the objective of the present study was to investigate the potential association between levels of personal growth and maternal age during pregnancy with the subsequent cognitive and motor neurodevelopment of the offspring at 6 months of age. Twenty-three pregnant women participated in this longitudinal study. The participants were assessed during the three trimesters of pregnancy using the Ryff Psychological Well-being Scale (Ryff, 1989). The neonates´ neurodevelopment was assessed using the BSID-III at 6 months of age. A multiple linear regression analysis was carried out using maternal growth during pregnancy and gestational age as independent variables, and the levels of cognitive and motor neurodevelopment of the babies at 6 months of age as dependent variables. The results showed that personal growth during pregnancy predicted cognitive neurodevelopment. Personal growth was also positively related with the scalar score of the fine motor subscale. Findings from this study suggest that maternal personal growth during pregnancy is a predictor of the later infants´ neurodevelopment at 6 months of age.

This study explores the perception of social and educational quality of life in minors with rare diseases (RDs). Two meta-analyses were performed, applying the random effects model. Results: Regarding the social Quality of Life, the meta-sample consisted of k = 40 samples, with a total population of 1943 children (mean age = 9.42 years), of whom 687 (35.3%) were girls, 615 (31.4%) were boys and 641 (33%) did not report their sex. The effect size was large (mean size = 7.68; p < 0.000; 99% Confidence Interval; lower limit = 7.22; upper limit = 8.14). The results of the meta-regression and model analysis showed the importance of the measurement instrument (Paediatric Quality-of-Life Inventory and Prototypes of the Quality of life) and the dissimilarity of perception among caregivers. The nationality and the type of RD were not relevant. With respect to the educational Quality of Life, the meta-sample consisted of k = 19 samples, with 699 minors (mean age = 10.3 years), of whom 266 (38%) were girls, 242 (34.6%) were boys and 191 (27.4%) did not report their sex. The effect size was large (mean size = 7.15; p < 0.000; 99% CI; lower limit = 6.35; upper limit = 7.94). The meta-regression and comparison of models showed that the type of RD was essential. The measurement instrument was a moderating variable, especially the Parent version Paediatric Quality-of-Life Inventory. This study reveals the need for further research on RDs and their social–educational effects.

To determine whether psychological variables (perceived stress, pregnancy-specific stress and psychopathology symptoms) and physiological variables (hair cortisol levels) are related to type of delivery (eutocic or instrumental delivery; spontaneous or induced labor).This was a longitudinal study.Spain.A total sample of 88 pregnant women.Perceived stress, pregnancy-specific stress, psychopathology symptoms and hair cortisol level were assessed in pregnant women throughout the third trimester of pregnancy until they gave birth. Participants were grouped by type of delivery (eutocic or instrumental delivery; spontaneous or induced labor). ANOVA tests were performed in order to determine differences between groups. We found differences between the eutocic and instrumental delivery groups in the SCL-90-R subscales somatisation (t = 6.98; p = 0.01), anxiety (t = 3.42; p 0.05), depression (t = 5.20; p 0.02) and psychoticism (t = 5.28; p 0.01), and in the general indices global severity index (t = 5.57; p 0.05) and positive symptoms (t = 5.21; p 0.01). No differences were found between groups for the other variables.Maternal psychological status could have an impact on delivery, since women who had an instrumental delivery presented more psychopathology symptoms in the third trimester.The psychological assessment and treatment of pregnant women could play a key role in enhancing maternal mental health and preventing the processes and outcomes associated with poor psychological status.

Purpose Stress is considered an important risk factor for the physical and psychological health of pregnant women. Hence, it is very important to study those protective factors that attenuate the negative effects of stress, such as resilience. The objective of this study was to verify the role of resilience as a stress-reducing factor during pregnancy. Methods A total of 151 pregnant women were assessed in this study: high resilience (n = 55) and low resilience (n = 96). Assessment consisted on perceived stress, pregnancy-specific stress, psychopathological symptoms, psychological wellbeing and Hair Cortisol Concentrations (HCC) during the third trimester of pregnancy and the puerperium, as well as postpartum depression. Results The results show that there were statistically significant differences between women with high and low resilience in: perceived stress [F (1,150) = 8.40; p = .005)], HCC [F (1,150) = 9.70; p = .002], pregnancy-specific stress [F (1,150) = 9.62; p = .002], and various subscales of psychopathological symptoms. Specifically, women with high resilience had lower levels of perceived stress, pregnancy-specific stress, psychopathological symptoms, psychological wellbeing, and Hair Cortisol Concentrations during the third trimester. During the puerperium, women in the high resilience group showed higher psychological wellbeing, lower psychopathological symptoms, and lower postpartum depression scores. Conclusions These results highlight the protective role of resilience when pregnant women are confronted by the negative effects of stress, and therefore the potential utility of resilience to improve the health of pregnant women and their neonates.

To translate and validate a Spanish-language version of the Birth Satisfaction Scale-Revised (BSS-R) and describe key measurement properties.A cross-sectional instrument validation design examining factor structure, validity and reliability.Three public hospital sites in Spain.202 women who had given birth within the past four weeks provided complete questionnaire data for analysis.Measures included the Spanish version of the BSS-R (S-BSS-R) and the Perceived Stress Scale (PSS). The tri-dimensional measurement model of the BSS-R was found to offer a good fit to Spanish data. Known-groups discriminant validity was found to be excellent with women experiencing a non-intervention delivery having higher S-BSS-R scores (p 0.05) compared to those having an intervention. Women who had no pain control were found to have greater S-BSS-R total and S-BSS-R women's attributes and stress experienced sub-scale scores compared to those who received pain control (p 0.05). Total scale internal reliability was also found to be acceptable. Evidence for good divergent and convergent validity was also found across total and sub-scale S-BSS-R scores.The S-BSS-R was found to have generally good to excellent psychometric properties and represents a valid and reliable translation of the original version of the BSS-R for use in Spanish-speaking populations. The development of the S-BSS-R enables comparison of birth satisfaction with international study data where the BSS-R is used.The relationship of both delivery type and pain control to birth satisfaction represent important areas for further research.

Ministry of Economy, Knowledge, Business and University of the Junta de Andalucia, Grant/Award Number: A-CTS-229-UGR18; European Regional Development Fund (ERDF); Spanish Ministry of Science, Innovation and Universities, Grant/Award Number: 18/00617, Objective: To compare the postpartum psychopathological symptoms of women who gave birth before the pandemic with those who gave birth during the pandemic. Methods: A total of 212 women participated in the study, of which 96 gave birth before the pandemic and 116 during the pandemic. Psychopathological symptoms, postpartum depression, perceived stress, and resilience were evaluated. Results: Women who gave birth during the pandemic had higher scores on somatization, obsessions and compulsions, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, and psychoticism. In addition, perceived stress was the common predictor of an increase in these symptoms. Conclusion: Postpartum is a complicated period in a woman's life. Many psychological adaptations take place and women may be subject to psychological alterations during this period. In addition, women who gave birth during the COVID-19 crisis may show greater psychological vulnerability, due to the specific situation experienced during the pandemic. The COVID-19 pandemic may have played a role in the increase in psychopathological symptoms after childbirth. Detecting possible symptoms postpartum plays a crucial role, because it allows intervening and preventing the development of psychopathologies., Ministry of Economy, Knowledge, Business and University of the Junta de Andalucia A-CTS-229-UGR18, European Commission, Spanish Ministry of Science, Innovation and Universities 18/00617

Postpartum post-traumatic stress disorder (PP-PTSD) affects 3.1-6.3% of women after childbirth. The City Birth Trauma Scale (City-BiTS) is a questionnaire designed to evaluate and diagnose this disorder, according to the DSM-5 criteria, including the following groups of symptoms characteristic of post-traumatic stress: re-experiencing, avoidance, negative cognitions and mood, and hyperarousal. The aim of the present study was to evaluate the psychometric properties of the Spanish-language version of this questionnaire (City-BiTS-S), based on a community sample of Spanish women. A total of 207 mothers, recruited at three health centres in southern Spain, completed the City-BiTS-S questionnaire and provided sociodemographic and obstetric data. Exploratory factor analysis (EFA) of the data replicated the two-factor structure reported in previous studies that explained 47.9% of the variance: Factor 1 of general symptoms, and Factor 2 of birth-related symptoms. Both City-BiTS-S (Cronbach’s α = 0.90) and the two factors (Cronbach’s α for Factor 1 = 0.89; Cronbach’s α for Factor 2 = 0.82) presented high internal consistency. Rasch analysis confirmed the unidimensionality of the two factors as valid subscales of the PP-PTSD. It also confirmed that the item about ‘Not being able to remember details of the birth’ should be reviewed. Rasch analysis also suggested the item ‘Flashbacks to the birth and/or reliving the experience’ should be reworded in the Spanish version. In conclusion, the City-BiTS-S presents appropriate psychometric properties to measure symptoms of postpartum_PTSD. Nevertheless, further research is recommended to confirm its validity in a clinical population and in different medical approaches to the birth process.

Stress during pregnancy has been widely studied and associated to different variables, usually with negative results for the health of the mother and the newborn, such as having a higher risk of suffering postpartum depression, premature birth, obstetrics complications or low birthweight, among others. However, there are not many lines of research that study the role that the sex of the baby plays on this specific stress and vice versa. Thus, the main objective was to analyse the relationship between the sex of the offspring and the stress of the mothers in the first trimester of pregnancy. In order to achieve this, 108 women had their biological stress measured (trough hair cortisol levels) and psychological stress evaluated (the Prenatal Distress Questionnaire (PSS), the Perceived Stress Scale (PDQ) and the Stress Vulnerability Inventory (IVE)). The results revealed significant differences in maternal hair cortisol levels in the first trimester based on the sex of the baby they had given birth to (t = −2.04; P < 0.05): the concentration of the hormone was higher if the baby was a girl (164.36: 54.45-284.87 pg/mg) than if it was a boy (101.13:37.95-193.56 pg/mg). These findings show that the sex of the future baby could be conditioned, among many other variables, by the mother´s stress levels during conception and first weeks of pregnancy. Further research is needed in this area to support our findings., Frontier Project “A-CTS-229-UGR18” of the Ministry of Economy, Knowledge, Business and University of the Junta de Andalucía, European Regional Development Fund (ERDF), Spanish Ministry of Science, Innovation and Universities, FPU program, reference number 18/00617, (Spanish Ministry of Economy, Industry and Competitiveness, FPI Program, reference number BES-2016-077619

Events that occur during fetal and perinatal life can have consequences on the health and disease of the offspring. The pioneering work on the "Fetal Programming Hypothesis" focused on pregnant women exposed to a great famine that occurred in the Netherlands at the end of World War II. The intrauterine environment of the babies during that famine caused them to low birthweight and determined the appearance of cardiovascular diseases in themselves when they reached adulthood, a risk that was transmitted even to the following generation. In addition to the general stress that a pregnant woman may suffer as a result of the death of a family member, suffering a war or natural disaster such as the SARS-CoV-2 coronavirus, there is another specific type of stress that refers exclusively to the pregnancy process; this is the pregnancy specific-stress. Pregnancy-specific stress is capable of sensitively predicting negative maternal and neonatal outcomes. This type of stress refers to the specific stress of pregnant women related to medical problems, the health of the newborn, the changes that the pregnancy will produce in their social relationships, prematurity, physical changes of pregnancy and fear of labor and birth. The objective of this article was to offer an updated information on pregnancy-specific stress and its consequences for maternal and neonatal health. Thus, we also proposed to offer strategies that midwives and psychologists can use to reduce pregnancy-specific stress levels. In conclusion, midwives and psychologists can work together to reduce pregnancy-specific stress levels.Los eventos que ocurren durante la vida fetal y perinatal pueden tener consecuencias sobre la salud y la enfermedad del neonato y del adulto. Los trabajos pioneros sobre la “Hipótesis de la Programación Fetal“ se centraron en embarazadas expuestas a una gran hambruna que ocurrió en Holanda al final de la Segunda Guerra Mundial. El ambiente intrauterino de los bebés durante esa hambruna condicionó que nacieran con un bajo peso y determinó la aparición de enfermedades cardiovasculares en ellos mismos al llegar a la edad adulta, riesgo que se trasmitió incluso a la siguiente generación. Además del estrés general que pueda sufrir una embarazada como consecuencia de la muerte de un familiar, sufrir una guerra o un desastre natural como la pandemia por el coronavirus SARS-CoV-2, existe otro tipo de estrés concreto y referido exclusivamente al proceso de embarazo: el estrés específico del embarazo. El estrés específico del embarazo es capaz de predecir de manera sensible resultados negativos maternos y neonatales. Este tipo de estrés se refiere al estrés concreto de las embarazadas en referencia a problemas médicos, la salud del recién nacido, los cambios que el embarazo va a producir en sus relaciones sociales, la posibilidad de un parto prematuro, los cambios físicos del embarazo y el miedo al parto y nacimiento. El objetivo de este artículo fue ofrecer información actualizada sobre el estrés específico del embarazo y sus consecuencias para la salud materna y neonatal. Así mismo, nos propusimos ofrecer estrategias que los profesionales sanitarios (incluidas las matronas) y los profesionales de la Psicología pudieran usar para reducir los niveles de estrés específico del embarazo. Como conclusión, afirmamos que las matronas y los profesionales de la Psicología pueden trabajar conjuntamente para reducir los niveles de estrés específico del embarazo.

This work was supported by the Frontier Project "ACTS229UGR18" of the Ministry of Economy, Knowledge, Business and University of the Junta de Andalucia, cosupported by funds/European Regional Development Fund (ERDF) - a way to build Europe. Beside, Mr. Jose Antonio PuertasGonzalez has been awarded with an individual research grant (Spanish Ministry of Science, Innovation and Universities, FPU program, reference number 18/00617) ., The aim was to examine the psychological effects caused by the COVID-19 pandemic on pregnant women, as well as the factors influencing these effects. The study design was cross-sectional and the participants were 200 pregnant women. The first group called the Pandemic Group (PG) included 100 women who were evaluated with psychological assessment instruments during the COVID-19 pandemic. The second group titled Pre-Pandemic Group (PPG) consisted of 100 women who were evaluated prior to the pandemic. Perceived stress, prenatal concerns and psychopathological symptoms were evaluated and compared. Pandemic Group scored significantly higher than Pre-Pandemic Group in the depression dimension of the SCL-90, in the phobic anxiety dimension, and in the Perceived Stress Scale. In addition, insomnia, along with having recently suffered the loss of a loved one explained 25% of the score variance in the depression dimension of the SCL-90. Insomnia also explained 13% of the variance of the results found in the Perceived Stress Scale. The fear of contagion by COVID-19 increased the scores obtained in the phobic anxiety dimension, explaining 11% of the variance. Thus, the COVID-19 pandemic could produce an increase in psychopathological symptomatology and stress, which can lead to negatively affecting pregnant women's mental health., Ministry of Economy, Knowledge, Business ACTS229UGR18, Junta de Andalucia, European Commission, Spanish Ministry of Science, Innovation and Universities, FPU program 18/00617

The pandemic caused by COVID-19, at a psychological level, can cause an increase in levels of stress and anxiety due to the fear of contagion and its consequences. Pregnant women are especially vulnerable to these psychological consequences. Thus, the objective of this study was to verify the efficacy of a cognitive-behavioral stress control program in reducing psychological stress and increasing resilience in pregnant women, which ended at the begining of the confinement due to COVID-19 in Spain.The study included 22 pregnant women who were randomly divided into two groups: the experimental group (GT) consisted of 11 participants and the control group (GC) also consisted of 11 participants. Participants were recruited from the Hospital Universitario Clínico San Cecilio in the province of Granada (Spain), where the weekly cognitive behavioral intervention was also carried out, which was implemented between January 22 and March 11, 2020. They used the assessment instruments: Pregnancy Distress Questionnaire (PDQ), Perceived Stress Scale (EEP-14), Inventory of Vulnerability to Stress (IVE) and Connor Davidson Resilience Scale (CD-RISC). A mixed ANOVA of repeated measures 2*2 was performed, with the variable between groups having two levels (CG and GT), and the within-subject having two time periods (pre and post).The repeated measures ANOVA analysis showed group*time interaction effects between the therapy group and the control group and the CD-RISC scores (FIt can be affirmed that cognitive behavioral intervention in pregnant women, administrated prior to confinement in Spain and during the COVID-19 pandemic, has resulted in increased levels of resilience in this population.La pandemia provocada por la COVID-19, a nivel psicológico, puede producir un aumento en los niveles de estrés y ansiedad por el miedo al contagio y sus consecuencias. Un grupo especialmente vulnerable a dichas consecuencias psicológicas es el de mujeres embarazadas. Así, el objetivo de este estudio fue comprobar la eficacia de un programa de control del estrés, de carácter cognitivo-conductual, en la reducción de estrés psicológico y el aumento de la resiliencia en mujeres embarazadas, que finalizó en el momento de la instauración del confinamiento por la COVID-19 en España.El estudio quedó constituido por veintidós mujeres embarazadas que fueron divididas en dos grupos de forma aleatoria: once constituyeron el grupo experimental (GT) y once el grupo control (GC). Las participantes fueron reclutadas del Hospital Universitario Clínico San Cecilio de la provincia de Granada (España), donde también se llevó a cabo la intervención cognitivo-conductual de carácter semanal, que se implementó entre el 22 de enero y el 11 de marzo de 2020. Se emplearon los siguientes instrumentos de evaluación: Cuestionario de Preocupaciones Prenatales (PDQ), Escala de Estrés Percibido (EEP-14), Inventario de Vulnerabilidad al Estrés (IVE) y Escala de Resiliencia de Connor y Davidson (CD-RISC). Se realizó un ANOVA mixto de medidas repetidas 2*2, teniendo la variable entre grupos dos niveles (GC y GT), y la variable intrasujeto dos momentos temporales (pre y post).El análisis ANOVA de medidas repetidas mostró efectos de interacción grupo*tiempo entre los grupos de terapia y control y las puntuaciones del CD-RISC (FSe puede afirmar que la intervención cognitivo-conductual en mujeres embarazadas, impartida de manera previa al confinamiento en España y durante la pandemia provocada por la COVID-19, ha provocado un incremento de los niveles de resiliencia en dicha población.

Background: Through the culture of thinness, increasingly promoted in our society as a beauty canon, it is not surprising that the number of people affected by eating disorders is increasing. Objective: This research aims to study the relationship between non-suicidal self-injuries and nuclear aspects of eating disorders specified along with this article. Methods: The sample consisted of 60 women diagnosed with anorexia and bulimia. Questionnaires assessing impulsivity, body satisfaction, alexithymia, body attitude and self-esteem were administered. Participants with non-suicidal self-harm were compared with those without it, and participants with anorexia with and without self-harm and participants with bulimia with and without self-harm were compared. Results: Differences were found in body dissatisfaction= 5.71; p ≤0.01), body attitudes= 4.80; p ≤0.02), self-esteem= 14.09; p ≤0.00) and impulsivity (t= 3.39; p ≤0.01) between participants with and without non-suicidal self-harm. Conclusions: These are key factors for the clinical area in the treatment of eating disorders to prevent the presence of self-harm, as it allows focusing the treatment target on those aspects such as dissatisfaction and impulsivity, which are key in the development of self-harm. Resumen Introducción: A través de la cultura de la delgadez, cada vez más promovida en nuestra sociedad como canon de belleza, no es de extrañar que este aumentado el número de personas afectadas por Trastornos de Conducta alimentaria. Objetivo: Estudiar la relación entre las autolesiones no suicidas y aspectos nucleares del trastorno de conducta alimentaria que se especifican a lo largo de este artículo. Métodos: La muestra ha sido formada por 60 mujeres diagnosticadas de anorexia y bulimia. Se administraron cuestionarios que evaluaban la impulsividad, satisfacción corporal, alexitimia, actitud corporal y autoestima. Se compararon aquellas participantes que presentaban autolesiones no suicidas con las que no lo presentaban, además se compararon participantes con anorexia con y sin autolesiones y participantes con bulimia con y sin autolesiones. Resultados: Se encontraron diferencias en insatisfacción corporal = 5,71; p ≤0.01), en actitudes corporales= 4.80; p ≤0.02), autoestima= 14.09; p ≤0.00) e impulsividad, (t= 3.39; p ≤0.01) entre participantes con y sin autolesiones no suicidas. Conclusiones: Estos son factores clave para la clínica en el tratamiento de los trastornos de conducta alimentaria para prevenir la presencia de autolesiones, ya que permite enfocar el objetivo del tratamiento a aquellos aspectos como la insatisfacción e impulsividad, que son claves en el desarrollo de autolesiones.

The COVID-19 global pandemic has forced millions of people to stay confined at home, increasing symptoms of anxiety and stress levels. Women who are also mothers, for their part, not only face the demands of motherhood but must combine working life with family life locked down in their homes. Main objective was to develop an explanatory model of the psychological consequences of COVID-19 and parental and perceived stress in mothers. A total of 261 mothers were evaluated coinciding with the lockdown imposed by the Spanish Government. The model displayed adequate indices and it was found that symptoms of anxiety in mothers increased the levels of perceived stress. The model allows to understand the close relationships between the psychological consequences of lockdown and stress in mothers. Understanding these relationships will help to prepare and direct psychological interventions in this population in the case of a possible new surge.

Objective The goal of this systematic-review and meta-analysis was to assess whether high maternal stress during pregnancy is associated with the development of pediatric pathology. Design Epidemiological peer-reviewed studies published in English or Spanish assessing associations between maternal stress during pregnancy and psychiatric and medical diseases were selected. Participants We retrieved 73,024 citations; 42 studies meeting inclusion criteria were assessed. Overall sample included 65,814,076 women. Findings Overall odds ratio for the development of a medical disease was OR=1.24 (CI95=1.11, 1.39), Z=3.85, p Key conclusions We concluded that exposure to high levels of stress during pregnancy are associated with autism spectrum disorder, obesity, and infantile colic in offspring. Implications for practice Maternal stress during pregnancy should be addressed to tackle its potential impact in health across the life span.

Objective: To compare stress levels throughout pregnancy in women who had conceived using assisted reproductive technology (ART) and women who had conceived naturally and somatometric values for infants. Background: Pregnant women who have received ART are exposed to high levels of stress. Methods: Ninety-one women attending a prenatal appointment at a Health Centre (Granada, Spain), and their 91 newborns participated in this study: 69 women conceiving naturally and 22 conceiving using ART. Assessment consisted of measuring hair cortisol levels, the Prenatal Distress Questionnaire, the Perceived Stress Scale and the Symptom Checklist-90-Revised. Results: Women conceiving using ART had higher cortisol levels in the first trimester than women who conceived naturally. In the third trimester, women who used ART reported higher levels of perceived stress than those who had conceived naturally. Maternal cortisol levels in the first trimester explained 32% of the variance in neonatal head circumference in the group of women who had conceived using ART. Conclusions: Women who had conceived using ART showed higher levels of cortisol in the first trimester and higher levels of perceived stress in the third trimester than women who had conceived naturally, rendering them more vulnerable to adverse outcomes. Maternal cortisol predicted the infants' development.

Objective to compare neurodevelopment differences between babies born from low-risk pregnancies and babies born from high-risk pregnancies. Study design Longitudinal design Setting Spain Participants A total of 91 women participated in the study, divided into two groups: 49 women in the low-risk pregnancy group and 42 women in the high-risk group. Measurement and findings The average amount of cortisol in pregnant mothers’ hair was determined in both groups. Following their birth, the babies’ neurodevelopment was evaluated using the Bayley-III instrument at 6 months of age and a new sample of cortisol was obtained from both the baby and the mother. The results showed that pregnancy risk group could predict cognitive, fine motor, gross motor and general motor neurodevelopment. Key Conclusions These results seem to show that an appropriate treatment tailored to the needs of individualised pregnancies may favor babies’ neurodevelopment, including that of babies born from high-risk pregnancies. Implications for research It is essential to take special care of pregnant women no matter their medical condition and offer them the best medical care available.

Objective To demonstrate the effectiveness of a cognitive behavioural therapy for stress management in pregnant women in the reduction of psychological stress and hair cortisol levels. Methods The trial was controlled and randomised, with a total of 78 pregnant women: control group (n-39) and Cognitive Behavioural Therapy group (n-39). To test the therapy's efficacy, an evaluation of the primary outcome (hair cortisol levels) and secondary outcomes (psychological stress, psychopathological symptomatology and resilience) was conducted before and after the treatment. The therapy was conducted during 8 sessions (one per week) in a group setting. The study was registered as a Randomised Controlled Trial with the code NCT03404141 . Results The results showed a group time interaction between hair cortisol levels, psychological stress (perceived and pregnancy-specific), and in the exacerbation and severity of psychopathological symptoms. These variables presented reductions after treatment only in the Cognitive Behavioural Therapy group. Conclusions Using a novel way of assessing chronic stress (psychological and objective measures as hair cortisol levels), this is the first study that has shown a decrease in both the levels of cortisol in hair and in psychological stress. This decline could have implications for maternal and fetal health.

Resumen Introducción: el índice de masa corporal (IMC) pregestacional afecta a la salud de la madre durante y después del embarazo, y se relaciona con un aumento del riesgo a sufrir diabetes gestacional, preeclampsia o muerte fetal. Además, el IMC pregestacional elevado aumenta los niveles de ansiedad, estrés y depresión, lo que conlleva al aumento de riesgo de aborto, bajo peso al nacer y prematuridad. Objetivos: comprobar si existen diferencias en estrés, síntomas psicopatológicos y variables fisiológicas durante el embarazo, entre embarazadas con IMC pregestacional normal e IMC pregestacional elevado. Métodos: han participado 156 mujeres embarazadas evaluadas longitudinalmente durante los tres trimestres de embarazo divididas en dos grupos: grupo con IMC pregestacional normal (n = 115) y grupo con IMC pregestacional elevado (n = 41). Se midieron niveles de estrés, síntomas psicopatológicos, hipertensión y glucosa. Resultados: los resultados mostraron que existían diferencias estadísticamente significativas entre los dos grupos en estrés específico del embarazo y en las subescalas del SCL-90-R: depresión, ideación paranoide y la escala de síntomas generales en el primer trimestre; en el segundo trimestre, en estrés específico del embarazo y subescalas (somatizaciones, obsesión compulsión, sensibilidad interpersonal, depresión, ansiedad, ideación paranoide y en las escalas generales; y en estrés percibido) y las subescalas somatizaciones, ansiedad y en la escala SP en el tercer trimestre. También se encontraron diferencias entre ambos grupos en tensión arterial diastólica en el primer trimestre, y en tensión arterial sistólica y diastólica en el tercer trimestre. Conclusiones: el IMC pregestacional elevado se relaciona con mayor estrés psicológico y con síntomas psicopatológicos y fisiológicos durante el embarazo.

Postpartum depression affects a huge number of women and has detrimental consequences. Knowing the factors associated with postpartum depression during pregnancy can help its prevention. Although there is evidence surrounding behavioral or psychological predictors of postpartum depression, there is a lack of evidence of biological forecasters. The aim of this study was to analyze the sociodemographic, obstetric, and psychological variables along with hair cortisol levels during the first, second, and third trimesters of pregnancy that could predict postpartum depression symptoms. A sample of 44 pregnant women was assessed during 3 trimesters of pregnancy and the postpartum period using psychological questionnaires and hair cortisol levels. Participants were divided into 2 groups: a group with postpartum depression symptoms and a group with no postpartum depression symptoms. Results showed significant positive differences between groups in the first trimester regarding the Somatization subscale of the SCL-90-R (p < .05). In the second trimester, significant differences were found in the Somatization, Depression, Anxiety, and GSI subscales (p < .05). In the third trimester significant differences between both groups were found regarding pregnancy-specific stress. We found significant positive differences between groups regarding hair cortisol levels in the first and the third trimester. Hair cortisol levels could predict 21.7% of the variance of postpartum depression symptoms. In conclusion, our study provided evidence that psychopathological symptoms, pregnancy-specific stress, and hair cortisol levels can predict postpartum depression symptoms at different time-points during pregnancy. These findings can be applied in future studies and improve maternal care in clinical settings.