1. Usefulness of FDG PET/CT in the management of tuberculosis
- Author
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Sánchez-Montalvá, Adrián, Barios, Marta, Salvador, Fernando, Villar, A., Tórtola, Teresa, Molina-Morant, Daniel, Lorenzo-Bosquet, Carles, Espinosa-Pereiro, Juan, Molina Romero, Israel, Universitat Autònoma de Barcelona, [Sánchez-Montalvá A, Salvador F, Espinosa-Pereiro J] Servei de Malalties Infeccioses, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Programa de salut internacional de l'Institut Català de la Salut (PROSICS), ICS, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. Grupo de Estudio de micobacterias (GEIM), Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), Madrid, Spain. [Barios M, Lorenzo-Bosquet C] Servei de Medicina Nuclear, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Villar A] Servei de Pneumologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Tórtola T] Servei de Microbiologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Programa de salut internacional de l'Institut Català de la Salut (PROSICS), ICS, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Molina-Morant D, Molina I] Servei de Malalties Infeccioses, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Programa de salut internacional de l'Institut Català de la Salut (PROSICS), ICS, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus
- Subjects
Bacterial Diseases ,Male ,0301 basic medicine ,Fevers ,Pathology and Laboratory Medicine ,030218 nuclear medicine & medical imaging ,0302 clinical medicine ,hidratos de carbono::desoxiazúcares::desoxiglucosa::fluorodesoxiglucosa F18 [COMPUESTOS QUÍMICOS Y DROGAS] ,Positron Emission Tomography Computed Tomography ,Medicine and Health Sciences ,Public and Occupational Health ,infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias grampositivas::infecciones por Actinomycetales::micobacteriosis::tuberculosis [ENFERMEDADES] ,Fever of unknown origin ,Young adult ,Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation, Computer-Assisted::Tomography, Emission-Computed::Positron-Emission Tomography::Positron Emission Tomography Computed Tomography [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,Lymph node ,Multidisciplinary ,Middle Aged ,Actinobacteria ,Hospitalization ,Infectious Diseases ,medicine.anatomical_structure ,Liver ,Cohort ,Carbohydrates::Deoxy Sugars::Deoxyglucose::Fluorodeoxyglucose F18 [CHEMICALS AND DRUGS] ,Tuberculosis Diagnosis and Management ,Medicine ,Female ,Fdg pet ct ,Radiology ,Anatomy ,medicine.symptom ,Research Article ,medicine.medical_specialty ,Tuberculosis ,Tuberculosi ,Science ,diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::interpretación de imágenes asistida por ordenador::tomografía computarizada radioisotópica::tomografía por emisión de positrones [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,Lymphatic System ,Lesion ,Young Adult ,03 medical and health sciences ,Signs and Symptoms ,Diagnostic Medicine ,Fluorodeoxyglucose F18 ,medicine ,Humans ,In patient ,Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Actinomycetales Infections::Mycobacterium Infections::Tuberculosis [DISEASES] ,Aged ,Bacteria ,business.industry ,Organisms ,Biology and Life Sciences ,Tropical Diseases ,medicine.disease ,Radiofàrmacs ,030104 developmental biology ,Lesions ,Tomografia per emissió de positrons ,Lymph Nodes ,business ,Mycobacterium Tuberculosis - Abstract
Tuberculosis; Positron emission tomography (PET); FDG Tuberculosis; Tomografía por emisión de positrones (PET); FDG Tuberculosi; Tomografia per emissió de positrons (PET); FDG BACKGROUND: The aim of our study is to describe the FDG-PET/CT findings in patients with tuberculosis and to correlate them with the patient's prognosis. METHODS: We retrospectively collected data from patients with tuberculosis, who had an FDG-PET/CT performed prior to treatment initiation from 2010 to 2015. RESULTS: Forty-seven out of 504 patients with active tuberculosis diagnosis (9.33%) underwent an FDG-PET/CT. The reasons for performing the FDG-PET/CT were: characterization of a pulmonary nodule (24; 51.1%), study of fever of unknown origin (12; 25.5%), study of lymph node enlargement (5; 10.6%) and others (6; 12.8%). Median age was 64 (IQR 50-74) years and 31 (66%) patients were male. Twenty-six (55.3%) patients had an immunosuppressant condition. According to the FDG-PET/CT, 48.6% of the patients had more than 1 organ affected and 46.8% had lymph node involvement. Median SUVmax of the main lesion was 5 (IQR 0.28-11.85). We found an association between the FDG accumulation and the size of the main lesion with a correlation coefficient of 0.54 (p
- Published
- 2019