1. Lack of response to bronchodilator of airway obstruction after mechanical ventilation in the newborn
- Author
-
A. Tal, Godfrey S, F. Eyal, and Bar-Yishay E
- Subjects
medicine.drug_class ,medicine.medical_treatment ,Specific Airway Conductance ,Thoracic gas volume ,Critical Care and Intensive Care Medicine ,Airway resistance ,Bronchodilator ,Medicine ,Humans ,Albuterol ,Lung Diseases, Obstructive ,Lung function ,Mechanical ventilation ,Respiratory Distress Syndrome, Newborn ,Inhalation ,business.industry ,Respiration ,Infant, Newborn ,Infant ,respiratory system ,Airway obstruction ,medicine.disease ,Respiration, Artificial ,respiratory tract diseases ,Bronchodilator Agents ,Anesthesia ,business ,Lung Volume Measurements ,Pulmonary Ventilation - Abstract
Thoracic gas volume (TGV) and specific airway conductance (SGaw) were measured in 6 infants, 21-42 weeks of age, who had been mechanically ventilated during the neonatal period. SGaw was significantly decreased while TGV was normal. Administration of a nebulized beta 2-sympathomimetic stimulant did not improve lung function. It is concluded that inhalation of beta 2 stimulant drugs is not effective in improving airway obstruction in infants with postventilation-elevated airway resistance and that this is likely to be of structural origin.
- Published
- 1982