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Over the recent few decades, use of biogas as a renewable source of energy has shown promising results. After the anaerobic digestion is complete, a large amount of residual biogas slurry (BGS) is obtained, whose management and disposal is a major problem. Mushroom cultivation offers one of the attractive alternatives for effectively managing this waste along with producing nutritious food. The present paper summarizes the results on cultivation of Agaricus bisporus and Pleurotus sajor-caju on wheat straw (WS) supplemented with BGS from a cow dung (CD) based biogas plant, and compares it with WS control. Maximum yield of 2.41 kg/10 kg compost A. bisporus (biological efficiency, 24.1%), and 950 g/kg dry substrate P. sajor-caju (biological efficiency, 95%) was observed. Non-edible oil cakes of mahua and karanja were also mixed with BGS of cow dung and used for P. sajor­caju cultivation. Highest yield of 976.5 g/kg dry substrate was obtained from the substrate combination, WS+20% mahua cake-BGS mixture, giving a biological efficiency of 97.6%. Results on proximate analysis showed that fruit bodies were rich in sugars and protein. The study thus proved beneficial for effective management of solid waste (biogas slurry, non-edible oil cakes) along with improving yield and nutrient content of mushrooms., Proceedings of the 24th European Biomass Conference and Exhibition, 6-9 June 2016, Amsterdam, The Netherlands, pp. 259-263