1. Semi-Supervised Learning of MRI Synthesis Without Fully-Sampled Ground Truths
- Author
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Mahmut Yurt, Onat Dalmaz, Salman Dar, Muzaffer Ozbey, Berk Tinaz, Kader Oguz, Tolga Cukur, Yurt, Mahmut, Dalmaz, Onat, Dar, Salman, Özbey, Muzaffer, and Çukur, Tolga
- Subjects
Radiological and Ultrasound Technology ,Image synthesis ,Magnetic Resonance Imaging ,Adversarial ,Computer Science Applications ,Magnetic resonance imaging ,Image Processing, Computer-Assisted ,Supervised Machine Learning ,Undersampled ,Electrical and Electronic Engineering ,Semi-supervised ,Algorithms ,Software ,Retrospective Studies - Abstract
Learning-based translation between MRI contrasts involves supervised deep models trained using high-quality source- and target-contrast images derived from fully-sampled acquisitions, which might be difficult to collect under limitations on scan costs or time. To facilitate curation of training sets, here we introduce the first semi-supervised model for MRI contrast translation (ssGAN) that can be trained directly using undersampled k-space data. To enable semi-supervised learning on undersampled data, ssGAN introduces novel multi-coil losses in image, k-space, and adversarial domains. The multi-coil losses are selectively enforced on acquired k-space samples unlike traditional losses in single-coil synthesis models. Comprehensive experiments on retrospectively undersampled multi-contrast brain MRI datasets are provided. Our results demonstrate that ssGAN yields on par performance to a supervised model, while outperforming single-coil models trained on coil-combined magnitude images. It also outperforms cascaded reconstruction-synthesis models where a supervised synthesis model is trained following self-supervised reconstruction of undersampled data. Thus, ssGAN holds great promise to improve the feasibility of learning-based multi-contrast MRI synthesis.
- Published
- 2022
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