1. Predicting the Outcome of Radical Radiotherapy for Invasive Bladder Cancer
- Author
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Hendry Wf, A'Hern Rp, Whitfield Hn, Slavin G, K. Liu, Plowman Pn, J. A. Vale, and Sowter C
- Subjects
medicine.medical_specialty ,Pathology ,Multivariate analysis ,Urology ,medicine.medical_treatment ,Urinary Bladder ,Metaplasia ,medicine ,Humans ,Neoplasm Invasiveness ,Aged ,Cell Size ,Neoplasm Staging ,Cell Nucleus ,Carcinoma, Transitional Cell ,Bladder cancer ,Urinary bladder ,business.industry ,Middle Aged ,Prognosis ,medicine.disease ,Squamous metaplasia ,Survival Rate ,Radiation therapy ,Treatment Outcome ,Transitional cell carcinoma ,medicine.anatomical_structure ,Urinary Bladder Neoplasms ,Multivariate Analysis ,T-stage ,medicine.symptom ,business - Abstract
The correlation between T stage, histological grade, the presence ofsquamous metaplasia, and nuclear morphometry scores and response to radiotherapy and survival was investigated in 60 patients with muscle invasive transitional cell carcinomas of the bladder. Patients with T 2 tumours showed a complete response significantly more often than those with T 3 lesions. Multivariate analysis showed that T stage and initial response to radiotherapy were very strong predictors of survival though they were not independent variables. Histological grade, the presence of squamous metaplasia, and nuclear morphometry scores were not found to have any predictive value
- Published
- 1993
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