1. A pilot study on using chlorine dioxide gas for disinfection of gastrointestinal endoscopes
- Author
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Wang Tao, Zhang Zongxing, Ma Shuren, Song Lin, Jin-hui Wu, Ying Yi, Hao Limei, and Jiancheng Qi
- Subjects
0301 basic medicine ,Endoscope ,Disinfectant ,030106 microbiology ,Gastrointestinal Endoscopes ,Pilot Projects ,General Biochemistry, Genetics and Molecular Biology ,Microbiology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Humans ,Inner diameter ,030212 general & internal medicine ,General Pharmacology, Toxicology and Pharmaceutics ,Spores, Bacterial ,Chlorine dioxide ,Chromatography ,General Veterinary ,Log reduction ,biology ,Chemistry ,Oxides ,Articles ,General Medicine ,biology.organism_classification ,Disinfection ,Endoscopes, Gastrointestinal ,Bacillus atrophaeus ,Chlorine Compounds - Abstract
Objectives: This pilot study of employing chlorine dioxide (CD) gas to disinfect gastrointestinal endoscopes was conducted to meet the expectations of many endoscopy units in China for a high-efficiency and low-cost disinfectant. Methods: An experimental prototype with an active circulation mode was designed to use CD gas to disinfect gastrointestinal endoscopes. One type of testing device composed of polytetrafluoroethylene (PTFE) tubes (2 m long, inner diameter 1 mm) and bacterial carrier containers was used to simulate the channel of the endoscope. PTFE bacterial carriers inoculated with Bacillus atrophaeus with or without organic burden were used to evaluate the sporicidal activity of CD gas. Factors including exposure dosage, relative humidity (RH), and flow rate (FR) influencing the disinfection effect of CD gas were investigated. Moreover, an autoptic disinfecting test on eight real gastrointestinal endoscopes after clinical use was performed using the experimental prototype. Results: RH, exposure dosage, organic burden, and the FR through the channel significantly (P
- Published
- 2016