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1. PS21 - 100. A PPAR -FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis

Author

Pingping Li, Robert R. Henry, Yun-Qiang Yin, Annette R. Atkins, Jay-Myoung Suh, Jerrold M. Olefsky, Ronald M. Evans, Mingxiao He, Henry Juguilon, Jamie Whyte, Ruth T. Yu, Colin T. Phillips, Johan W. Jonker, Maryam Ahmadian, and Michael Downes

Subjects
chemistry.chemical_classification, medicine.medical_specialty, Metabolic homeostasis, Adipose tissue, Peroxisome proliferator-activated receptor, Biology, FGF1, medicine.disease, Endocrinology, chemistry, Diabetes mellitus, Internal medicine, medicine, human activities
Abstract

Although feast and famine cycles illustrate that remodelling of adipose tissue in response to fluctuations in nutrient availability is essential for maintaining metabolic homeostasis, the underlying mechanisms remain poorly understood.

Published
2012

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