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Ning Gao,1,* Meng Li,2,* Weiming Wang,1 Lei Wang,3 Zhen Liu,4 Yufeng Guo1 1Department of Acupuncture and Moxibustion, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China; 2Department of Gastroenterology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China; 3Department of Dermatology, China-Japan Friendship Hospital, Beijing, 100020, People’s Republic of China; 4Department of Gastroenterology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhen Liu, Department of Gastroenterology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, No. 1 Xiyuan Playground, Haidian District, Beijing, People’s Republic of China, Email doctorliuzhen@126.com Yufeng Guo, Department of Acupuncture and Moxibustion, Guang’ an Men Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange St., Xicheng District, Beijing, People’s Republic of China, Email gamgyf@139.comBackground: In recent years, the incidence of herpes zoster has risen steeply, the exact pathogenesis of the acute pain and the transformation into postherpetic neuralgia are still obscure, and the absence of effective management remains a major therapeutic challenge. The purpose of this study was to perform a qualitative and quantitative bibliometric analysis of the 100 most cited papers on herpes zoster.Materials and methods: Related literature were retrieved from the Web of Science Core Collection. Excel and VOSviewer software were applied to quantitatively analyze, and construct the bibliometric network charts.Results: The Top 100 most-cited papers published between 2000 and 2018 showed a fluctuating downward trend. The most studies were published in the year of 2000 (n = 12). The article entitled “A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults” from Oxman MN, was the most-cited publication. The United States was the most contributing country, followed by the United Kingdom, and Italy. Finland occupied the highest citations per publication (CPP). The University of Colorado topped the list of institutions with the most publications with 18 articles and also had the most citations (average citations: 281.78 per article). Myron J Levin from the University of Colorado School of Medicine is the most published and most cited researcher overall, whereas Duke University’s John W Gnann tops the list in terms of average CPP.Conclusion: In terms of the quantity of T100 articles, researchers, and organizations, the US is the predominant country. The most T100 papers were published in the special journal Clinical Infectious Diseases. The most academic focus remain the remedies for postherpetic neuralgia and vaccine development for individualized groups.Keywords: herpes zoster, bibliometric study, top-cited, citation, VOSviewer

Chloropropanols such as 3-monochloropropane-1,2-diol (3-MCPD) and 1,3-dichloro-2-propanol (1,3-DCP) have drawn increasing attention due to their release from food contact paper and their potential carcinogenic effects. In this study, the effects were investigated of water extraction conditions on release of chloropropanols from food contact paper, and the extraction efficiencies of chloropropanols by water extract and migration method were compared. Cold water was found to be more severe than hot water for extraction of chloropropanols, with the highest water extraction value obtained at 23°C. Two hours of extraction was sufficient as the chloropropanols can be fully extracted from food contact paper within a short period of time. Increase of temperature in the range of 10°C-60°C had little impact on release of chloropropanols, however, the extraction of chloropropanols decreased when high temperatures (80°C or above) were applied due to volatilisation losses. Hence, attention should be paid when choosing extract conditions representing the worst-case scenario. The water extraction value using EN 645 method gives higher results compared to migration test described in GB 31604.1 and GB 5009.156, suggesting that the water extract method was probably more severe. For migration test, aqueous-based simulants were found to be more conservative than oil-based simulants, suggesting the conventional experiment conditions applicable for compliance test of chloropropanols migration can be simplified and optimised.

Commercial Chinese ink was employed to disperse pristine vapor-grown carbon nanofibers (VGCNFs) in aqueous suspensions via horizontal ball milling. The obtained suspension was used to fabricate conductive paper-based composites through filtration-deposition onto filter paper. It was found that the carbon black particles from the Chinese ink helped separate VGCNFs and acted as connection points between the VGCNFs, while the glue reinforced the conduction network. Thus, the VGCNF-ink/paper ternary composite showed sufficiently low sheet resistance. With merely 2.5 mg·cm−2 VGCNFs, the sheet resistance could be reduced to 4.5 Ω·sq−1. As a proof of concept, these paper-based composites were directly used as electrodes of solid-state symmetric electronic double-layer capacitors (EDLCs) and the substrate for the electrodeposition of MnO2 to achieve higher electrochemical performances. The EDLCs fabricated with 2.5 mg·cm−2 VGCNFs showed a specific capacitance of 224 mF·cm−2 at a current density of 1 mA·cm−2, which was retained by 86.4% after 10,000 charge-discharge cycles. Moreover, thanks to the high electrical conductivity and the porous structure, the MnO2 decorated paper-based composites exhibited dramatically enhanced specific capacitance. It is believed that our finding offers an idea to directly utilize commercial Chinese ink for the fabrication of electrode materials.

The pulp and paper industry converts roundwood and recycled fibre, collected from wastepaper into printing and writing papers, and other specialty grades of paper. The pulp and paper mills in Ontar...

For the first time, molecular dynamics simulation was used to analyse the solubility of five kinds of nanoparticles (SiO2, ZnO, Al2O3, Fe2O3, TiO2), cellulose crystalline region and cellulose molec...

This practitioner paper presents the case of a small paper business named JNA Pulp, initiated with the vision to provide high-quality imported paper to the market. The paper discusses several hurdl...

Ruminants would suffer from gastric distension (bloat) when feeding on alfalfa (Medicago sativa L.; Alf), while tannins can relieve this problem. Thus, this study aimed to evaluate the effect of Alf mixed with paper mulberry (Broussonetia papyrifera) leaves (PML) or condensed tannins (CT) extracted from PML on in vitro fermentation performance. Seven experimental treatments based on the mass ratios of Alf and PML were set up: Alf, PML, 3A1P (Alf:PML = 3:1), 1A1P (Alf:PML = 1:1), 1A3P (Alf:PML = 1:3), A1P (Alf with 1% CT extracted from PML), A2P (Alf with 2% CT extracted from PML), and a blank. The results after fermentation were as follows. (1) The degradable dry matter (DDM) and degradable organic matter (DOM) contents increased simultaneously with the increase in the proportion of PML (p .05), propionic, and butyric acids compared to Alf alone. Adding CT improved the concentrations of propionic and butyric acids over the Alf treatment (p

The paper industry wastewater even after bio-treatment at industrial scale is a major source of aquatic and soil pollution due to various unknown compounds. Hence, the study has focused on the detection of residual organic pollutants from the bleached and unbleached paper mill wastewater and both sources showed endocrine-disrupting compounds. The toxicity test with Phaseolus aureus seed germination showed inhibition of seed germination and alpha-amylase activity >25% in bleached and unbleached paper mill wastewater. The LC50 of Tubifex tubifex was noted of >50% after 48 hours incubation test. This revealed that the wastewater discharged from bleached paper mill is more toxic than unbleached paper mill waste this might be due to the use of more chemicals during bleaching and pulping process. This study has revealed that there is need to treat both paper mill wastewaters adequately prior to discharge.

In this article the author outlines his understanding of self-psychology as an independent psychoanalytic treatment paradigm created by the late Heinz Kohut and initially geared toward the psychoan...

Sustainability demands circular and material solutions with an emphasis on using local resources. Using alternative fibers from invasive plants and agro-residue promotes local production in smaller...

The aim of this study was to explore the note-taking experiences of university students using paper-based (non-electronic) and paperless (electronic) resources. By means of a hermeneutic phenomenol...

A novel platform for the phenolics in wastewater based on an electrochemical multiwalled carbon nanotube paper-based analytical device (MWCNT-ePAD) has been developed. Phenolics such as catechol ar...

This article discusses a scoping review of position papers aimed at enhancing the quality of life of people with intellectual disabilities. It describes the approach taken to conducting the scoping...

Cenobamate is a new antiseizure medication (ASM) recently introduced in the USA for the treatment of adults with focal-onset seizures. In March 2021, the European Commission authorized its use for the adjunctive treatment of focal-onset seizures with or without secondary generalization (focal seizures with or without progression to bilateral tonic-clonic seizures, according to current ILAE terminology) in adults with epilepsy not adequately controlled despite the treatment with at least two ASMs. This review summarizes the mechanism of action, efficacy, and safety of Cenobamate. The authors provide their expert opinions on the use of this drug. The aim of this paper is to report on the Italian preliminary experience with the use of cenobamate, focusing on treatment goals, optimal dosing and titration schedules, strategies to minimize adverse effects, and identification of suitable candidates for treatment. There was agreement that slow titration may improve tolerability, and that clinically significant benefit can be achieved in many patients at relatively low doses. A favorable response to relatively low doses of cenobamate could be an early predictor of ultimate responsiveness. Overall, cenobamate is a welcome new treatment for adults with focal seizures resistant to conventional ASMs.

Introduction: Lithium treatment is considered the gold standard for the long-term management of bipolar disorder and recurrent unipolar depression. It is also extremely effective in other psychiatric conditions characterized by impulsivity and aggression, and for the prevention of suicidal behaviours. Areas covered: This paper provides a scoping review and an expert commentary regarding the use of lithium in adult patients. Available information about efficacy, tolerability, dosing, and switching is analyzed, and the strategies that may be most useful in real-world clinical settings are highlighted. Expert opinion: Lithium is effective on different domains of bipolar disorder, including the long-term prevention of recurrences of affective episodes, management of acute mania as well as in the prophylaxis of all affective episodes. Lithium has been defined a 'forgotten drug,' since its use in routine clinical practice has been declined over the last 20 or 30years. Reasons for this trend include lack of adequate training on the management of lithium side effects. Considering its efficacy, use of lithium in ordinary clinical practice should be promoted. Several strategies, such as using slow-release formulations, can be easily implemented in order to minimize lithium side effects and improve its tolerability profile.

The microstructure of fibrous paper plays an important role in its property investigation. In this study, an approach is proposed to extrapolate a 2D image into a virtual 3D microstructure. Five types of handsheets made of different pulps were prepared. Then, a hybrid function of two-point correlation and lineal-path function (S2&L2) and co-occurrence correlation functions (CCFs) was used in the simulated annealing reconstruction method. Thus, microstructures of two-phase fiber-pore handsheets were reconstructed using 2D scanning electron microscopy images. Finally, penetration simulations and calculations of the absolute permeability of handsheets were conducted. The statistical values of two-point correlation function (S2) and lineal-path function (L2) extracted from the reconstructed images were used to characterize the reconstruction accuracy, and the comparisons of reconstruction accuracy and time were made. The study results showed that the 3D microstructures of fibrous handsheets could be reconstructed effectively by S2&L2 and CCFs, identifying with the targets. The accuracies were around 10−5, and the reconstruction times by CCFs were shortened by 30–60% compared with S2&L2. Moreover, the visual permeability simulation results could reflect the structural difference of handsheets, according to the calculated absolute permeability. These findings provide a guidance for 3D reconstruction of natural fiber paper.

It is estimated that more than 500 species of insects have been introduced to the Galápagos Islands via human activities. One of these insect invaders is the yellow paper wasp, Polistes versicolor (Olivier) (Hymenoptera: Vespidae), a social wasp native to continental South America. In Galápagos, these wasps are voracious predators of insect larvae, compete with native species for insect prey or for floral resources and are a human nuisance. Wasp suppression methods currently in use are inefficient and attract non-target species, calling for the development of species-specific attractants that can be used in baits to lure and kill wasps. To evaluate the potential for using wasp semiochemicals in baits, we determined the biochemical composition of the head, thorax, Dufour’s and venom glands of P. versicolor foragers via gas chromatography/mass spectrometry (GC/MS). Male and female wasps were tested for behavioral responses to body segment extracts from both sexes. Female body extracts consistently elicited more behavioral responses in both male and female wasps than male extracts. Females reacted to female head, thorax and abdomen (the Dufour’s and venom glands are located in the abdomen) extracts, whereas males reacted significantly to female head and thorax extracts. One male body extract, the head, elicited two significant behaviors: female wasps groomed more often, and males touched the filter paper more often compared to the blank control. Head extracts consistently changed the behavior of female and male wasps and, together with female thorax extracts, have potential as species-specific lures for yellow paper wasps. Heads were mainly composed of hydrocarbon lipids and oleamide, a ligand for odorant-binding proteins. The thorax consisted of fatty aldehydes, long-chain alkanes and fatty amide lipids. Field trials of blends of these compounds in high wasp density areas of Galápagos are the next step to confirm if any of these compounds are attractive to P. versicolor.

This work aims to explore the potentialities of an end-user personalisation platform in industrial settings. In such a context, stakeholders with different roles and competencies collaborate to manage and control an environment where legacy machines coexist and interact with newer ones. Our goal is to provide a rule-based tool that allows end-users to build personalised solutions to respond quickly to the dynamic needs of factories. We report on a case study in the paper factory domain, in which the industrial aspects identified with expert stakeholders through interviews have been simulated and addressed through an extension of a personalisation platform. A first user test of the resulting environment has been carried out with a representative set of users, and has provided useful and encouraging feedback in terms of the potentialities of the proposed approach in industrial contexts.

In reaction to the Covid-19 pandemic, the Chinese authorities have installed visa restrictions and strict quarantine rules to prevent foreigners from spreading new infections to the country. This has disrupted a trend of increasing European Union (EU)-China travel and socio-economic exchanges. EU citizens living in or travelling to China have had to deal with the consequences of Beijing’s so-called Zero-Covid strategy. In view of quasi-closed borders, many Europeans have given up on living in or travelling to China. Those who have stayed have come up with strategies of adaptation, while European-owned firms have reacted by adopting initiatives such as doing business online or localising staff. Overall, the Chinese visa restrictions have added a new dimension to the debate on asymmetries in EU-China relations.

The thriving development of the paper industry leaves behind a great amount of pulp and paper mill sludge (PPMS), which constitutes a considerable source of pollution. Experts estimate that...

The anatomical and chemical properties of a lesser known species, Kawui wood, were investigated Two trees were examined based on IAWA, ASTM and SNI. A completely randomised design was used with rad...