1,294,048 results
Search Results
202. Smartphone-based image analysis coupled to paper-based colorimetric devices
- Author
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Sanghyo Kim, SeJin Kim, Hyung-Tae Ha, and Dami Kim
- Subjects
010302 applied physics ,business.industry ,Computer science ,Color correction ,Detector ,General Physics and Astronomy ,02 engineering and technology ,Paper based ,021001 nanoscience & nanotechnology ,Chip ,01 natural sciences ,Image (mathematics) ,Set (abstract data type) ,Transformation (function) ,ComputerSystemsOrganization_MISCELLANEOUS ,0103 physical sciences ,Convergence (routing) ,General Materials Science ,Computer vision ,Artificial intelligence ,0210 nano-technology ,business - Abstract
Advancements in technology have led to the use of smartphones as biosensor detectors. However, it is difficult to obtain stable color information of colorimetric sensors using multiple smartphones owing to different light conditions and image correction operations. In this study, we attempted color detection of the colorimetric paper chip using smartphone-embedded light-emitting diode (LED) and simple transformation calculation. This method enables the acquisition of stable color information using different smartphones by reducing the influence of external light sources. Moreover, we studied characteristics such as convergence and distinction of detection result details by the manufacturers and smartphones. These findings suggested the necessity of classification criteria for the use of smartphones to achieve optimal detection. In addition, white and black references were used to set the standard for color correction of various light sources. Based on our results, we conclude that this approach presents the possibility of smartphone-based colorimetric detection in practical applications.
- Published
- 2020
203. Joint Position Paper of the Working Group of Pacing and Electrophysiology of the French Society of Cardiology (SFC) and the Société française d’imagerie cardiaque et vasculaire diagnostique et interventionnelle (SFICV) on magnetic resonance imaging in patients with cardiac electronic implantable devices
- Author
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Jacques Mansourati, Louis Boyer, A Jacquier, Didier Klug, Nicolas Sadoul, Olivier Piot, Philippe Maury, Laurent Fauchier, Lucie Cassagnes, Frédéric Anselme, Jérôme Taieb, F. Sacher, B. Dubourg, Michel Chauvin, Daniel Gras, Jean-Nicolas Dacher, Eloi Marijon, Hubert Cochet, Gabriel Laurent, Axel Bartoli, Estelle Gandjbakhch, Serge Boveda, François Pontana, Nouvelles Cibles Pharmacologiques de la Protection Endothéliale et de l'Insuffisance Cardiaque (EnVI), CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pitié-Salpêtrière [APHP], DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Service de cardiologie [Strasbourg], CHU Strasbourg, Service de cardiologie [CHU Rouen], Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Normandie Université (NU), Image Science for Interventional Techniques (ISIT), Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université-Centre National de la Recherche Scientifique (CNRS), Institut d’Electronique et des Systèmes (IES), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), service d'Imagerie, Centre Hospitalier Universitaire de Clermont-Ferrand, IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Adhésion et Inflammation (LAI), Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Service de cardiologie Pédiatrique [Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département Cardiologie, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Météorologie Dynamique (UMR 8539) (LMD), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-École polytechnique (X)-École des Ponts ParisTech (ENPC)-Centre National de la Recherche Scientifique (CNRS)-Département des Géosciences - ENS Paris, École normale supérieure - Paris (ENS Paris)-École normale supérieure - Paris (ENS Paris), Biospectroscopie Translationnelle - EA 7506 (BIOSPECT), Université de Reims Champagne-Ardenne (URCA), Récepteurs nucléaires, maladies cardiovasculaires et diabète (EGID), Université de Lille, Droit et Santé-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Bordeaux (UB), Service de Cardiologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Clinique Pasteur, Toulouse, France., Centre de résonance magnétique biologique et médicale (CRMBM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS), Working Group of Pacing, Electrophysiology of the French Society of Cardiology, Société française d’imagerie cardiaque et vasculaire diagnostique et interventionnelle (SFICV)., CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département des Géosciences - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École des Ponts ParisTech (ENPC)-École polytechnique (X)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, DACHER, Jean Nicolas, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital de la Timone [CHU - APHM] (TIMONE), CHU Clermont-Ferrand, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Clermont Université-Centre National de la Recherche Scientifique (CNRS)-Université d'Auvergne - Clermont-Ferrand I (UdA), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Européen Georges Pompidou [APHP] (HEGP), and Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)
- Subjects
medicine.medical_specialty ,Medical device ,Cardiac pacing ,artificial ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Internal medicine ,Medicine ,Radiology, Nuclear Medicine and imaging ,In patient ,Magnetic resonance imaging (MRI) ,Contraindication ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,medical device ,business.industry ,Magnetic resonance imaging ,General Medicine ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Pacemaker ,030220 oncology & carcinogenesis ,Cardiology ,Position paper ,Safety ,business ,Defibrillators - Abstract
International audience; Magnetic resonance imaging (MRI) has become the reference imaging for the management of a large number of diseases. The number of MR examinations increases every year, simultaneously with the number of patients receiving a cardiac electronic implantable device (CEID). A CEID was considered an absolute contraindication for MRI for years. The progressive replacement of conventional pacemakers and defibrillators by MR-conditional CEIDs and recent data on the safety of MRI in patients with "MR-nonconditional" CEIDs have progressively increased the demand for MRI in patients with a CEID. However, some risks are associated with MRI in CEID carriers, even with "MR-conditional" devices because these devices are not "MR-safe". A specific programing of the device in "MR-mode" and monitoring patients during MRI remain mandatory for all patients with a CEID. A standardized patient workflow based on an institutional protocol should be established in each institution performing such examinations. This joint position paper of the Working Group of Pacing and Electrophysiology of the French Society of Cardiology and the Société française d'imagerie cardiaque et vasculaire diagnostique et interventionnelle (SFICV) describes the effect and risks associated with MRI in CEID carriers. We propose recommendations for patient workflow and monitoring and CEID programming in MR-conditional, "MR-conditional nonguaranteed" and MR-nonconditional devices.
- Published
- 2020
204. Reducing antibiotic prescribing and addressing the global problem of antibiotic resistance by targeted hygiene in the home and everyday life settings: A position paper
- Author
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Charles P. Gerba, Sumanth Gandra, Sabiha Y. Essack, Sally F. Bloomfield, Patrice Courvalin, Jean-Yves Maillard, Elizabeth Scott, and Joseph R. Rubino
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Sanitation ,Epidemiology ,media_common.quotation_subject ,Context (language use) ,Global Health ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Hygiene ,Drug Resistance, Bacterial ,Health care ,Global health ,Humans ,Medicine ,Infection control ,030212 general & internal medicine ,Everyday life ,Prescription Drug Overuse ,media_common ,0303 health sciences ,030306 microbiology ,business.industry ,Health Policy ,Public Health, Environmental and Occupational Health ,Bacterial Infections ,Anti-Bacterial Agents ,Infectious Diseases ,Position paper ,business - Abstract
Antimicrobial resistance (AMR) continues to threaten global health. Although global and national AMR action plans are in place, infection prevention and control is primarily discussed in the context of healthcare facilities with home and everyday life settings barely addressed.\ud \ud As seen with the recent global SARS-CoV-2 pandemic, everyday hygiene measures can play an important role in containing the threat from infectious microorganisms.\ud \ud This position paper has been developed following a meeting of global experts in London, 2019. It presents evidence that home and community settings are important for infection transmission and also the acquisition and spread of AMR. It also demonstrates that the targeted hygiene approach offers a framework for maximizing protection against colonization and infections, thereby reducing antibiotic prescribing and minimizing selection pressure for the development of antibiotic resistance. If combined with the provision of clean water and sanitation, targeted hygiene can reduce the circulation of resistant bacteria in homes and communities, regardless of a country's Human Development Index (overall social and economic development). Achieving a reduction of AMR strains in healthcare settings requires a mirrored reduction in the community.\ud \ud The authors call upon national and international policy makers, health agencies and healthcare professionals to further recognize the importance of targeted hygiene in the home and everyday life settings for preventing and controlling infection, in a unified quest to tackle AMR.
- Published
- 2020
205. The optimisation of fingermark enhancement by VMD and Lumicyano™ on thermal paper
- Author
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Benjamin Jones, Joanna Fraser, Paul B. Sherriffs, and Kevin J. Farrugia
- Subjects
Materials science ,Solvent free ,Latent fingerprint enhancement ,010401 analytical chemistry ,Vacuum Metal Deposition ,chemistry.chemical_element ,solvent free ,Thermal paper ,Zinc ,01 natural sciences ,environmentally friendly techniques ,0104 chemical sciences ,Pathology and Forensic Medicine ,Highly sensitive ,one step superglue fuming ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Chemical engineering ,chemistry ,Ninhydrin ,thermal paper ,030216 legal & forensic medicine ,Science, technology and society - Abstract
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. The enhancement of fingermarks on thermal paper can be challenging due to background staining caused by polar solvents used in fingermark enhancement techniques such as ninhydrin. This study explored a commercial one-step superglue fuming process, Lumicyano™, and Vacuum Metal Deposition (VMD) to develop fingermarks on this substrate and overcome this issue. Different sequential treatments involving Lumicyano™ and a combination of VMD methods were investigated with varying degrees of success with some sequences being highly sensitive. The VMD processes, however, were observed to generally be more effective at enhancing marks, whereas Lumicyano™ provided little or no benefit on this paper type. The results indicate that Lumicyano™ is only beneficial as a pre-treatment when the entire sequence of gold/zinc and silver/zinc is taken to completion. The gold/zinc and silver/zinc VMD processes were optimised on five different thermal papers, and the optimised techniques were then directly compared to determine which was more successful on each thermal paper type as a single treatment.
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- 2020
206. Rapid DNA detection using filter paper
- Author
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Yajing Song and Peter Gyarmati
- Subjects
Paper ,0106 biological sciences ,Dendrimers ,Materials science ,Surface Properties ,Bioengineering ,Superparamagnetic beads ,01 natural sciences ,Magnetics ,03 medical and health sciences ,chemistry.chemical_compound ,Limit of Detection ,Rapid dna ,010608 biotechnology ,Dendrimer ,Highly porous ,Polyamines ,Cellulose ,Molecular Biology ,Amination ,030304 developmental biology ,0303 health sciences ,Filter paper ,Methanol ,DNA ,General Medicine ,Combinatorial chemistry ,Microspheres ,chemistry ,Duplex (building) ,Filtration ,Thiocyanates ,Biotechnology - Abstract
Point-of-care (POC) detection is crucial in clinical diagnosis in order to provide timely and specific treatment. Combining polyamidoamine (PAMAM) dendrimer, p-phenylene diisothiocyanate (PDITC) and superparamagnetic beads, a novel method to activate the surface of filter paper to bind DNA molecules has been developed. The method is based on the primary amination of the filter paper surface with PAMAM dendrimer, followed by generation of isothiocyanate groups via PDITC, and subsequent repetition of these two steps. Different parameters of the process have been optimized, including probe printing, preparation of target DNAs and detection. The result shows that, due to the highly porous structure of filter paper, high amounts of printed probes, target DNAs and magnetic beads can provide high signal intensities in the detection area via probe/target duplex formation. This method is suitable for rapid, specific and cost-efficient DNA detection on cellulose filter paper. It can be used as a POC device, in particular for diagnosis and treatment management of infectious diseases and identification of antimicrobial drug resistance genes.
- Published
- 2020
207. Effect of HRT on performance of hybrid upflow anaerobic sludge blanket (HUASB) reactor using bio balls in treatment of pulp and paper mill bagasse wash water
- Author
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P. Ravichandran and K. Balaji
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010302 applied physics ,business.industry ,Pulp (paper) ,Paper mill ,02 engineering and technology ,Raw material ,engineering.material ,Biodegradation ,021001 nanoscience & nanotechnology ,Pulp and paper industry ,01 natural sciences ,Wastewater ,Biogas ,0103 physical sciences ,engineering ,Environmental science ,0210 nano-technology ,business ,Bagasse ,Mesophile - Abstract
Enormous quantities of bagasse are being used as raw material in agro based large integrated pulp and paper mills. Anaerobic technology is an effective means of biodegradation of organic substance in wastewater and energy production of biogas that can be used as an alternative fuel. This study illustrates the effect of HRT on performance of lab scale hybrid upflow anaerobic sludge blanket (HUASB) reactor on treatment of pulp and paper mill bagasse wash water. The lab scale HUASB reactor was designed for an effective volume of 0.013 m3 with bio balls as packing media at the top of reactor and operated under mesophilic condition. After startup period, the reactor was operated with HRTs of 23.55, 15.98, 12.00, 10.03 and 7.97 h for the average influent COD concentrations of 2503.6 mg/L, 3918 mg/L, 5432 mg/L, 6608 mg/L and 7996 mg/L respectively. The results showed that the maximum COD removal efficiencies and TSS removal efficiencies were in the range of 68.60–92.19% and 89.56–94.66% respectively. The minimum and maximum biogas yield of 0.32 and 0.53 m3/kg CODa were obtained at influent concentration of 2503.6 mg/L and 7996 mg/L respectively.
- Published
- 2020
208. Paper-based microfluidic devices for food adulterants: Cost-effective technological monitoring systems
- Author
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Rohitraj Ray, Anusha Prabhu, Dinesh Prasad, Vijay kumar Garlapati, Tejraj M. Aminabhavi, Naresh Kumar Mani, and Jesus Simal-Gandara
- Subjects
Paper ,3309.12 Aditivos Alimentarios ,2302.90 Bioquímica de Alimentos ,Cost-Benefit Analysis ,Lab-On-A-Chip Devices ,3309 Tecnología de los Alimentos ,Microfluidics ,General Medicine ,Microfluidic Analytical Techniques ,Food Science ,Analytical Chemistry - Abstract
Financiado para publicación en acceso aberto: Universidade de Vigo/CISUG Analytical sciences have witnessed emergent techniques for efficient clinical and industrial food adulterants detection. In this review, the contributions made by the paper-based devices are highlighted for efficient and rapid detection of food adulterants and additives, which is the need of the hour and how different categories of techniques have been developed in the past decade for upgrading the performance for point-of-care testing. A simple strategy with an arrangement for detecting specific adulterants followed by the addition of samples to obtain well-defined qualitative or quantitative signals for confirming the presence of target species. The paperbased microfluidics-based technology advances and prospects for food adulterant detection are discussed given the high-demand from the food sectors and serve as a valued technology for food researchers working in interdisciplinary technological frontiers. Vision Group on Science and Technology, Government of Karnataka | Ref. KSTePS/ VGST/SMYSR-2016–17/GRD-595/2017–18 Vision Group on Science and Technology, Government of Karnataka | Ref. KSTePS/VGSTRGS/F/GRD No.711/2017–18 Science and Engineering Research Board (SERB), Department of Science and Technology, Govt of India | Ref. CRG/2020/003060
- Published
- 2022
209. Experts or charlatans? ICO analysts and white paper informativeness
- Author
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David Florysiak and Alexander Schandlbauer
- Subjects
Economics and Econometrics ,Platform economy ,Initial coin offerings ,Information content ,Textual analysis ,White paper ,Expert ratings ,Signaling ,Finance - Abstract
White papers are likely the primary source of information provided to potential Initial Coin Offering (ICO) investors in platform-based ventures that may reduce information asymmetry between ICO issuers and investors. We use textual analysis to measure the information content of white paper documents. We examine how an informative white paper content signal and a concurrent potentially biased expert rating signal correlate with measures of ICO funding success, ICO underpricing, and post-ICO performance. Our empirical results suggest that high-quality ICO issuers signal their type by providing more informative white paper content, i.e., excess or new textual information not contained in recent and peer white papers. However, investors rely on the expert ratings signal in their decision to buy tokens that “jams” the white paper informative content signal. Once listed tokens receive a market valuation, white paper informative content is positively associated with our measures for underpricing, returns, and liquidity, while the expert ratings signal is rendered irrelevant.
- Published
- 2022
210. All-in-one paper-based sampling chip for targeted protein analysis
- Author
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Trine Grønhaug Halvorsen, Øystein Skjærvø, and Léon Reubsaet
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Paper ,medicine.drug_class ,Calibration curve ,02 engineering and technology ,Monoclonal antibody ,Chorionic Gonadotropin ,01 natural sciences ,Biochemistry ,Mass Spectrometry ,Analytical Chemistry ,Human chorionic gonadotropin ,Limit of Detection ,medicine ,Humans ,Environmental Chemistry ,Trypsin ,Sample preparation ,Amino Acid Sequence ,Spectroscopy ,Whole blood ,Chromatography ,Filter paper ,Chemistry ,010401 analytical chemistry ,Antibodies, Monoclonal ,Reproducibility of Results ,Sampling (statistics) ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Reagent ,Proteolysis ,Dried Blood Spot Testing ,0210 nano-technology ,Antibodies, Immobilized ,Biomarkers ,Chromatography, Liquid - Abstract
A novel all-in-one paper-based sampling concept for mass spectrometric bottom-up protein analysis is here demonstrated in a chip format integrating instant immunocapture, protein reduction, - alkylation and tryptic digestion all in-device. Conventional laboratory grade filter paper was coated with the polymer 2-hydroxyethyl methacrylate-co-2-vinyl-4,4-dimethyl azlactone (pHEMA-VDM) with a subsequent covalent immobilization of the monoclonal antibody E27 targeting the biomarker human chorionic gonadotropin (hCG). In-device protein reduction and alkylation was optimized with regards to reagent concentration and reaction pH. The sampling concept showed a high degree of performance between 10 and 1000 ng/mL (R2 > 0.99) by a five-point calibration curve sampled with hCG spiked to human serum samples and freshly collected whole blood samples, respectively. LOD (experimentally obtained at 100 pg/mL (2.64 pM/0.9 IU/L)) was demonstrated to be up to ten times lower with more than six times faster sample preparation than what has previously been reported for on-paper analysis of hCG in human serum samples.
- Published
- 2019
211. A paper-based analytical device coupled with electrochemical detection for the determination of dexamethasone and prednisolone in adulterated traditional medicines
- Author
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Orawon Chailapakul, Vitsarut Primpray, Manabu Tokeshi, Wanida Laiwattanapaisal, and Theerasak Rojanarata
- Subjects
Paper ,Chromatography, Paper ,Prednisolone ,Ethyl acetate ,02 engineering and technology ,Electrochemical detection ,01 natural sciences ,Biochemistry ,Dexamethasone ,Analytical Chemistry ,chemistry.chemical_compound ,Limit of Detection ,medicine ,Environmental Chemistry ,Electrodes ,Spectroscopy ,Detection limit ,Chromatography ,010401 analytical chemistry ,Electrochemical Techniques ,021001 nanoscience & nanotechnology ,Carbon ,0104 chemical sciences ,Partition coefficient ,Paper chromatography ,Pharmaceutical Preparations ,chemistry ,Printing, Three-Dimensional ,Plant Preparations ,Differential pulse voltammetry ,Drug Contamination ,0210 nano-technology ,medicine.drug - Abstract
The adulteration of herbal medicines by dexamethasone or prednisolone is regarded as a serious problem in many communities. Herein, a novel platform for the separation and quantification of both target steroids in herbal medicines based on electrochemical paper-based analytical devices (ePADs) has been created. The ePAD was composed of Whatman SG81 chromatography paper, 3D-printed devices and a commercial screen-printed electrode. Whatman SG81 silica-coated paper was used for the separation of dexamethasone and prednisolone based on the difference in their partition coefficients during the flow of the mobile phase. The optimal mobile phase was composed of 60% ethyl acetate in cyclohexane and required 7 min for separation. The separated steroids on the paper were then quantified by electrochemical detection using differential pulse voltammetry, in which the 3D-printed devices facilitated the measurement. Analytical detection ranges of 10–500 μg mL−1 were obtained for both dexamethasone and prednisolone (r2 = 0.988 and 0.994, respectively). The limits of detection for dexamethasone and prednisolone were 3.59 and 11.98 μg mL−1, respectively, whereas the limits of quantification were 6.00 and 20.02 μg mL−1, respectively. The amounts of both target steroids derived from real herbal medicine samples determined by the proposed method were comparable to those obtained with assays using standard high-performance liquid chromatography. In addition, a simple evaporation step can be used to increase the concentration of the samples before analysis. These ePADs are simple, low-cost, rapid, and very promising for on-site quantitative detection.
- Published
- 2019
212. Biofunctionalized cellulose paper matrix for cell delivery applications
- Author
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Anupam Apoorva, Manchikanti Padmavati, Tarun Agarwal, Sudip Ghosh, Birendra Behera, and Tapas K. Maiti
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Paper ,Cell type ,02 engineering and technology ,Biochemistry ,Diffusion ,Extracellular matrix ,Mice ,03 medical and health sciences ,chemistry.chemical_compound ,Structural Biology ,In vivo ,Animals ,Humans ,Cellulose ,Molecular Biology ,030304 developmental biology ,Drug Carriers ,0303 health sciences ,Coated paper ,Propylamines ,Chemistry ,Substrate (chemistry) ,Serum Albumin, Bovine ,Hep G2 Cells ,General Medicine ,Adhesion ,Silanes ,021001 nanoscience & nanotechnology ,Triethoxysilane ,Hepatocytes ,Biophysics ,Gelatin ,Muramidase ,Adsorption ,Stem cell ,0210 nano-technology ,Porosity - Abstract
The present study delineates the preparation, characterization, and application of (3-Aminopropyl)triethoxysilane (APTES)/Caprine liver-derived extracellular matrix (CLECM) coated paper matrix for cell delivery. Here, we exploited positively charged surface of the paper matrix (as imparted by APTES derivatization) to improve the biological responses of the cells. Our results demonstrated that the functionalized paper matrixes favored the adhesion, growth, and proliferation of multiple cell types including normal, transformed, cancerous, and stem cells as compared to the pristine paper matrix. Upon implantation into the mice model, the developed paper matrix supported infiltration of the host cells and vasculature without showing any evidence of significant systemic toxicity. Moreover, the cells cultured on the paper matrix, when delivered to the CAM and mouse models, showed an enhanced vascular network around the substrate, thereby confirming its potential to deliver the cells in vivo. Together, the study confirms that the reported paper-based platform is easy to fabricate, cheap, portable and could efficiently be applied to cell delivery applications for either tissue repair or the development of humanized animal model.
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- 2019
213. Irradiation based clean and energy efficient thermochemical conversion of biowaste into paper
- Author
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Shailesh Pathak, Harald Großmann, Rene Kleinert, Prateek Saxena, and A. K. Ray
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Bamboo ,Materials science ,Renewable Energy, Sustainability and the Environment ,Strategy and Management ,Pulp (paper) ,Energy consumption ,engineering.material ,Raw material ,Pulp and paper industry ,Industrial and Manufacturing Engineering ,stomatognathic diseases ,stomatognathic system ,visual_art ,Newsprint ,engineering ,visual_art.visual_art_medium ,Bagasse ,Kraft paper ,General Environmental Science ,Efficient energy use - Abstract
The advancement in plastic and plastic based products in last two decades has imposed a serious threat to the environment. This has led to an increase in the demand for sustainable and biobased products. Paper and paper products are good alternatives to their plastic counterparts. A key element of paper industry is the raw material (wood, bamboo and nonwood agricultural residues such as bagasse, straws etc.) from which pulp is produced. The pulp is then utilized for production of paper. There are many pulping processes to prepare pulp of various qualities. For fine grade pulp, chemical pulping is used. The chemical pulp is produced by soda, kraft and sulphite pulping processes. However, for newsprint grade pulp, stone ground wood (SW), thermomechanical (TMP), chemi-thermomechanical (CTMP), chemi-mechanical (CMP) or refiner mechanical (RMP) corresponding pulping processes are employed. The method of pulp preparation (pulping process) consumes large amount of energy and chemicals. A new pulping process with electron irradiation using biowaste (bagasse) as a raw material is discussed in this work. Bagasse pulping process is found to reduce about 50% of energy consumption during pulping process. The process is referred to as ‘ECTMP’ (Energy Efficient Chemi-Thermo Mechanical Pulping). The paper produced from aforesaid method also reflected no loss of strength properties with respect of TMP reference pulps. Henceforth, preliminary calculation based on experimental results shows that the proposed bagasse ECTMP process explored the scope of energy savings of the order of 50%.
- Published
- 2019
214. Intense Pulsed Light unprinting for reducing life-cycle stages in recycling of coated printing paper
- Author
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Keri Rickman, Chih-Hung Chang, Changqing Pan, Rajiv Malhotra, and Michael Dexter
- Subjects
Potential impact ,Coated paper ,Materials science ,Renewable Energy, Sustainability and the Environment ,business.industry ,Scanning electron microscope ,020209 energy ,Strategy and Management ,medicine.medical_treatment ,05 social sciences ,Context (language use) ,02 engineering and technology ,Intense pulsed light ,Micrography ,Industrial and Manufacturing Engineering ,Paper recycling ,Colored ,050501 criminology ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Optoelectronics ,business ,0505 law ,General Environmental Science - Abstract
Unprinting of paper can reduce multiple life-cycle stages in the recycling of paper to yield significant environmental impact. Laser-unprinting has been demonstrated for uncoated paper but causes significant damage to coated paper. This work explores a scalable optical (non-laser) process for unprinting coated paper. Printed coated paper is exposed to pulsed broad-spectrum Intense Pulsed Light (IPL) from a xenon lamp and the toner is then removed by dabbing gently with an ethanol wipe. While black toner is easily unprinted, unprinting of colored prints (red, blue, green) is best realized by incorporating an initial overprint of black toner. An unprinting throughput on the order of mm2/s is achieved. Three distinct regimes of unprinting are identified based on the extent of toner removal and damage of the paper. The optical properties of the unprinted paper, characterized via UV–Visible spectrophotometry, are correlated to these regimes to understand the potential for in-situ optical process monitoring. Scanning Electron Micrography and Fourier-Transform Infrared Spectroscopy are performed to understand the underlying mechanisms that govern the occurrence of the different unprinting regimes. Further, the potential impact of the developed approach on recycling of paper is discussed in the context of the capabilities of current optical unprinting approaches and the potential elimination of life-cycle stages in conventional paper recycling.
- Published
- 2019
215. Three-dimensional paper based platform for automatically running multiple assays in a single step
- Author
-
Wu Yupan, Hongyuan Jiang, Yongda Yan, Yukun Ren, and Lianhuan Han
- Subjects
Paper ,Detection limit ,business.industry ,Dynamic range ,Chemistry ,Point-of-care testing ,Troponin I ,010401 analytical chemistry ,Microfluidics ,Single step ,Electrochemical Techniques ,02 engineering and technology ,Paper based ,Folding (DSP implementation) ,Microfluidic Analytical Techniques ,021001 nanoscience & nanotechnology ,01 natural sciences ,Multiplexing ,0104 chemical sciences ,Analytical Chemistry ,Automation ,Colorimetry ,0210 nano-technology ,business ,Computer hardware - Abstract
Paper based assays are paving the way to automated, simplified, robust and cost-effective point of care testing (POCT). We propose a method for fabricating three dimensional (3D) microfluidic paper based analytical devices (μPADs) via combining thin adhesive films and paper folding, which avoids the use of cellulose powders and the complex folding sequence and simultaneously permits assays in several layers. To demonstrate the effectiveness of this approach, a 3DμPADs was designed to conduct more assays on a small footprint, allowing dual colorimetric and electrochemical detections. More importantly, we further developed a 3D platform for implementing automated and multiplexed ELISA in parallel, since ELISA, a routine and standard laboratory method, has rarely been used in practical analyses outside of the laboratory. In this configuration, complex and multistep diagnostic assays can be carried out with the addition of the sample and buffer in a simple fashion. Using Troponin I as model, the device showed a broad dynamic range of detection with a detection limit of 0.35 ng/mL. Thus, the developed platforms allow for various assays to be cost-effectively carried out on a single 3D device, showing great potential in an academic setting and point of care testing under resource-poor conditions.
- Published
- 2019
216. A colorimetric assay for sensitive detection of hydrogen peroxide and glucose in microfluidic paper-based analytical devices integrated with starch-iodide-gelatin system
- Author
-
Yun Lei, Zi-Zhen Guo, Lian Xin, Liu Mengmeng, Xinhua Lin, Ai-Lin Liu, Wei Chen, Hui-Hong Huang, Xing-Hua Xia, Hui Liu, and Hua-Ping Peng
- Subjects
Paper ,food.ingredient ,Starch ,02 engineering and technology ,01 natural sciences ,Gelatin ,Analytical Chemistry ,chemistry.chemical_compound ,food ,Humans ,Glucose oxidase ,Hydrogen peroxide ,Detection limit ,Reproducibility ,Chromatography ,biology ,Filter paper ,010401 analytical chemistry ,Color reaction ,Hydrogen Peroxide ,Iodides ,Microfluidic Analytical Techniques ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Glucose ,chemistry ,biology.protein ,Colorimetry ,0210 nano-technology - Abstract
Microfluidic paper-based analytical devices (μPADs) for detection of hydrogen peroxide and glucose have been developed. The analytical performance of colorimetric detection using the conventional starch-iodine color reaction has been significantly improved by using gelatin as the surface modifier which retains the enzyme activity in the dry filter paper strip, improves antioxidability, as well as decreases the strong background signal. Under optimal conditions, the color intensities show a good linear relationship with glucose concentration ranging from 0.5 to 5 mM and hydrogen peroxide concentration from 0.5 to 6 mM, with the detection limit of 0.05 mM and 0.1 mM, respectively. In addition, the accuracy of colorimetric sensor has been successfully assessed in detecting glucose from real human serum samples and recovery value ranges from 95.7% to 97%, which are approaching to the glucose oxidase endpoint. The new colorimetric assay exhibits high sensitivity, good selectivity, acceptable stability and reproducibility. The present approach is promising for monitoring glucose for point of care diagnostic applications, especially in regions with resource-limited settings.
- Published
- 2019
217. Paper-microfluidics based SERS substrate for PPB level detection of catechol
- Author
-
Krishna Chaitanya Vishnubhatla, Sai Manohar Chelli, Sai Muthukumar, Naresh Krishna Narasimha, Maurizio Ferrari, Siva Kumar Belliraj, and Abishek Hariharan
- Subjects
Materials science ,Microfluidics ,Ab initio ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,Hemocyanin ,01 natural sciences ,Silver nanoparticle ,Inorganic Chemistry ,symbols.namesake ,chemistry.chemical_compound ,Quinone complex ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,Spectroscopy ,Catechol ,SERS ,MBTH ,Organic Chemistry ,Substrate (chemistry) ,Paper-microfluidics ,Paper based ,Surface-enhanced Raman spectroscopy ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,chemistry ,Catechol sensor ,symbols ,0210 nano-technology ,Raman spectroscopy - Abstract
The application of microfluidics for largescale rapid analytics holds great promise in the pharmaceutical diagnostics and analytical chemistry. Here we report a paper based microfluidic substrate designed by the impregnation of Silver nanoparticles. This study demonstrates the achievement of a thousand-fold increase in the successful detection level up to 10 ppb (90.8 nM) by employing Surface Enhanced Raman Spectroscopy (SERS) for the detection of Catechol. The presented sensor exhibits the following main features: (i) high specificity of enzyme (Hemocyanin)-based sensing, (ii) effective SERS sensitivity, (iii) easiness and cost-effectiveness of a paper-based platform. We rationalize these findings using the ab initio DFT simulations using Gaussian 09 whose theoretical calculations reflect the observed experimental Raman peaks.
- Published
- 2019
218. Author-related and reader-related aspects of historical papers: A commentary on Lorch’s paper 'Defining ‘Normal’: Methodological Issues in Aphasia and Intelligence Research'
- Author
-
Guido Gainotti
- Subjects
Neuropsychology and Physiological Psychology ,Cognitive Neuroscience ,Intelligence ,Aphasia ,Humans ,Experimental and Cognitive Psychology - Published
- 2022
219. New insights into pollutants removal, toxicity reduction and microbial profiles in a lab-scale IC-A/O-membrane reactor system for paper wastewater reclamation
- Author
-
Shengdao Shan, Lifeng Ping, and Zhuang Haifeng
- Subjects
Paper ,Environmental Engineering ,010504 meteorology & atmospheric sciences ,Nitrogen ,Daphnia magna ,Ultrafiltration ,Industrial Waste ,Wastewater ,010501 environmental sciences ,Waste Disposal, Fluid ,01 natural sciences ,Water Purification ,Bioreactors ,Animals ,Environmental Chemistry ,Waste Management and Disposal ,Effluent ,0105 earth and related environmental sciences ,Biological Oxygen Demand Analysis ,Pollutant ,Membrane reactor ,biology ,Chemistry ,Chemical oxygen demand ,Membranes, Artificial ,biology.organism_classification ,Pulp and paper industry ,Pollution ,Acute toxicity ,Daphnia ,Water Microbiology ,Filtration ,Water Pollutants, Chemical - Abstract
In this study, an internal circulation-anoxic/aerobic (IC-A/O) process followed by ultrafiltration (UF) and reverse osmosis (RO) system was applied for paper wastewater reclamation. The IC-AO system presented a stable and efficient performance, achieving high removal of chemical oxygen demand (COD), total organic carbon (TOC) and total nitrogen (TN) with methane production rate of 132.8 mL/d. Acute toxicity to Daphnia magna (D. magna) was reduced significantly (83.2%) and the spearman's rank correlation analysis indicated that the toxicity of effluents from each reactor were positively correlated with COD and TOC. Hexadecanoic acid, octadecanoic acid and benzophenone were the main toxic contributors for biological effluent. Microbial community revealed that Anaerolinea was significantly related with organic pollutants. The UF-RO system further removed pollutants and toxicity with the final effluent COD, TOC, ammonium nitrogen (NH4+-N) and TN of 32.6, 18.8, 0.3 and 9.2 mg/L, respectively, which proved that it was feasible for paper wastewater reuse. This study presented an efficient, practical and environmentally competitive system, and paved a foundation for the treatment and reuse of paper wastewater.
- Published
- 2019
220. Instrument-free enrichment and detection of phosphopeptides using paper-based Phos-PAD
- Author
-
Yuhong Xiang, Jianqiao Chang, Yimeng Geng, Li Liping, Lu Zhang, Hong Qiang, Hanni Zhao, and Yuxian Wang
- Subjects
Paper ,Phosphopeptides ,Titanium ,Chromatography ,Clinical screening ,Surface Properties ,Phosphopeptide ,Chemistry ,Tio2 nanoparticles ,Breast Neoplasms ,Paper based ,Pixel intensity ,Serum samples ,Biochemistry ,Analytical Chemistry ,Humans ,Nanoparticles ,Environmental Chemistry ,Colorimetry ,Female ,Bromphenol Blue ,Particle Size ,Tetrabromophenol Blue ,Quantitative analysis (chemistry) ,Spectroscopy - Abstract
The facile detection of phosphopeptides is important for clinical screening and phosphoproteomic research. This work develops an instrument-free, cost-effective, convenient paper-based method for quantitative analysis of phosphorylated peptides. With a novel portable device, Phos-PAD, this method can achieve selective enrichment and colorimetric detection of phosphopeptides within 15 min TiO2 nanoparticle-based chemisorption and tetrabromophenol blue-based colorimetric assay were integrated into the single paper-based analytical device. The color change can indicate the presence of phosphopeptides and the mean pixel intensity of the red channel can be used for phosphopeptide quantification. With capability of quantifying phosphopeptides in serum samples, this Phos-PAD assisted phosphopeptide assay may attract significant attention to clinical analysis of endogenous serum phosphopeptides.
- Published
- 2019
221. Optimal scheduling ratio of recycling waste paper with NSGAII based on deinked-pulp properties prediction
- Author
-
Yin Liu, Wenhao Shen, Panos Seferlis, Yi Man, and Zhang Liu
- Subjects
021103 operations research ,General Computer Science ,business.industry ,Computer science ,Pulp (paper) ,0211 other engineering and technologies ,General Engineering ,Waste paper ,02 engineering and technology ,engineering.material ,Deinking ,law.invention ,law ,Optimal scheduling ,0202 electrical engineering, electronic engineering, information engineering ,engineering ,020201 artificial intelligence & image processing ,Process engineering ,business - Abstract
The recycling of waste paper has been an effective way to achieve the environmental-friendly growth of papermaking industry. Focusing on the mixed-pulping process which has been generally employed, to ensure the required properties of the deinking pulp (DIP) and minimize the purchase cost of waste paper, an intelligent model scheduling the mixing ratio of waste paper was developed in the study. Primarily, driven by the field data of mixing ratio of waste paper and DIP properties, the prediction models of DIP properties were developed by SVM, GA-SVM, and BP-NN algorithms. Subsequently, based on the best prediction model, the scheduling model for the mixing ratio of waste paper was set up by NSGAII algorithm. The experimental results showed that, based on the obtained best BP-NN prediction model of DIP properties, the developed NSGAII scheduling model for the ratio of waste paper could achieve excellent scheduling results under the rigorous constraints and multi-objective. Compared with the previous study, the developed prediction and scheduling models in this study reduced the purchase cost of waste paper by 2.16%, and improved the acceptable proportion of DIP property from 56.07% to 100%.
- Published
- 2019
222. Paper platform for determination of bumetanide in human urine samples to detect doping in sports using digital image analysis
- Author
-
Leonardo Pezza, Eduardo Luiz Rossini, Helena Redigolo Pezza, L. S. Lima, Vitor Hugo Marques Luiz, and Universidade Estadual Paulista (Unesp)
- Subjects
Digital image analysis ,Detection limit ,Materials science ,Chromatography ,Filter paper ,010401 analytical chemistry ,Doping ,Paper platform ,02 engineering and technology ,Urine ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Analytical Chemistry ,Digital image ,medicine ,0210 nano-technology ,Bumetanide ,Spectroscopy ,medicine.drug - Abstract
Made available in DSpace on 2019-10-06T17:04:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-06-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Development and application of a new, simple, inexpensive, and eco-friendly method is presented for the quantification of bumetanide in human urine samples for the detection of doping in sports. The method involves the use of a paper platform and digital image detection and is based on the reaction between bumetanide, p-dimethylaminocinnamaldehyde (p-DAC), and HCl in a methanolic medium, yielding a colored compound in a delimited area on a qualitative filter paper. The concentrations of p-DAC and HCl were optimized by a chemometric experimental design. After the addition of the reagents to the paper, digital images were obtained by scanning in a multifunctional printer and analyzed using the RGB pattern. The linear bumetanide concentration range was 6.90 × 10 −5 –1.37 × 10 −3 mol L −1 with R 2 = 0.993 and the limits of detection (LOD) and quantification (LOQ) were 3.60 × 10 −4 and 1.09 × 10 −4 mol L −1 , respectively. A SPE clean-up step for the samples were required to eliminate the interference of urinary urea. The recoveries obtained varied from 94% to 105%, indicating the absence of significant matrix effects or interferences in urine samples after clean-up step. The proposed method was successfully applied to the analysis of bumetanide in human urine samples. Instituto de Química Universidade Estadual Paulista “Júlio de Mesquita Filho” UNESP, R. Prof. Francisco Degni 55, P.O. Box 355 Instituto de Química Universidade Estadual Paulista “Júlio de Mesquita Filho” UNESP, R. Prof. Francisco Degni 55, P.O. Box 355 CAPES: 001 FAPESP: 2015/21733-1
- Published
- 2019
223. Surface-Enhanced Raman scattering (SERS) filter paper substrates decorated with silver nanoparticles for the detection of molecular vibrations of Acyclovir drug
- Author
-
Vahid Eskandari, Hossein Sahbafar, Elaheh Karooby, Masoud Hakimi Heris, Saeideh Mehmandoust, Damoun Razmjoue, and Amin Hadi
- Subjects
Instrumentation ,Spectroscopy ,Atomic and Molecular Physics, and Optics ,Analytical Chemistry - Published
- 2023
224. Nanoporous oxide coating on carbon paper electrodes to enable bio-hydrogen production in microbial electrolysis cells
- Author
-
Pratiksha Srivastava, Cristina González, Jesus Palma, and Enrique Garcia-Quismondo
- Subjects
General Chemistry ,Catalysis - Published
- 2023
225. Numerical solution of differential and differential-algebraic equations. Selected papers from NUMDIFF-16
- Author
-
Martin Arnold, Maren Hantke, Raphael Kruse, Helmut Podhaisky, Elena Celledoni, Jason Frank, and Jens Lang
- Subjects
Computational Mathematics ,Applied Mathematics - Published
- 2023
226. Study on cellulose nanofibers (CNF) distribution behaviors and their roles in improving paper property
- Author
-
Zonghong Lu, Hao Zhang, Liqin Liu, Haibing Cao, Zhengbai Cheng, Hongbin Liu, and Xingye An
- Subjects
Agronomy and Crop Science - Published
- 2023
227. Numerical simulation of steam condensation on the surface of a horizontal tube using the VOF method. A comment on the results from Li Shu and Yonglin Ju paper 'Numerical Study on the Condensation Characteristics of Various refrigerants outside a horizontal Plain tube at low temperatures', International Journal of Thermal Sciences, 2022
- Author
-
Konstantin Minko
- Subjects
General Engineering ,Condensed Matter Physics - Published
- 2023
228. In-situ etching activation towards flexible carbonized paper-supported electrode with transition-metal oxides embedded into carbonized cellulose fibers
- Author
-
Yu Shi, Yuren Liu, Jiyuan Zhang, Xiujie Huang, and Xueren Qian
- Subjects
Agronomy and Crop Science - Published
- 2023
229. Integrated enzyme hydrolysis assisted cellulose nanofibril (CNF) fabrication: A sustainable approach to paper mill sludge (PMS) management
- Author
-
Jing Li, Navid E. Alamdari, Burak Aksoy, Mahesh Parit, and Zhihua Jiang
- Subjects
Environmental Engineering ,Health, Toxicology and Mutagenesis ,Public Health, Environmental and Occupational Health ,Environmental Chemistry ,General Medicine ,General Chemistry ,Pollution - Published
- 2023
230. 'We are out of toilet paper': Testing the mediating effect of product scarcity on consumers’ competitive arousal in family firms
- Author
-
Francesca Serravalle, Gazi Mahabubul Alam, and Elisa Giacosa
- Subjects
Marketing ,Competitive arousal ,Impulse buying ,Information overload ,Customer journey ,Family firms ,Product scarcity - Published
- 2023
231. Introduction to the Special Section on the Best Papers from REFSQ 2022
- Author
-
Vincenzo Gervasi and Andreas Vogelsang
- Subjects
Software ,Computer Science Applications ,Information Systems - Published
- 2023
232. MOFs-derived niobium oxide nanoparticles/carbon nanofiber hybrid paper as flexible binder-free electrode for solid-state asymmetric supercapacitors
- Author
-
Md. Wasi Ahmad, Baban Dey, Asad Syed, Ali H. Bahkali, Meenakshi Verma, Duck-Joo Yang, and Arup Choudhury
- Subjects
Mechanics of Materials ,Mechanical Engineering ,Materials Chemistry ,Metals and Alloys - Published
- 2023
233. Highly thermally conductive flexible insulated PI/BNNS@rGO nanocomposite paper with a three-dimensional network bridge structure
- Author
-
Baokang Yu, Yuhang Zhou, Zhouai Luo, Jie Fan, Jianxin He, Yong Liu, and Xuling Jin
- Subjects
General Physics and Astronomy ,Surfaces and Interfaces ,General Chemistry ,Condensed Matter Physics ,Surfaces, Coatings and Films - Published
- 2023
234. Assessing life-cycle GHG emissions of recycled paper products under imported solid waste ban in China: A case study
- Author
-
Huijing Deng, Dingfan Zhang, Huajun Yu, Yi Man, and Yutao Wang
- Subjects
Environmental Engineering ,Environmental Chemistry ,Pollution ,Waste Management and Disposal - Published
- 2023
235. Novel optical method based on nebulization assisted laser induced plasma on inexpensive paper substrates for online determination of halogens and metals in liquid samples
- Author
-
Cristina Méndez-López, Luis Javier Fernández-Menéndez, Cristina González-Gago, Jorge Pisonero, and Nerea Bordel
- Subjects
Electrical and Electronic Engineering ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials - Published
- 2023
236. All-natural water-resistant paper coated by chitosan nanowhiskers through hydrophilic-to-hydrophobic self-assembly
- Author
-
Hyo Jeong Kim, Lam Tan Hao, Ga-Hyeun Lee, Sejin Choi, Han Gi Chae, Dongyeop X. Oh, Hyungjun Kim, and Youngho Eom
- Subjects
General Chemical Engineering ,Organic Chemistry ,Materials Chemistry ,Surfaces, Coatings and Films - Published
- 2023
237. Paper-based bipolar electrode electrochemiluminescence sensors for point-of-care testing
- Author
-
Tinglei Ma, Suyue Ren, Yixiang Wang, Haihan Yu, Lin Li, Xu Li, Luqing Zhang, Jinghua Yu, and Yan Zhang
- Subjects
Electrochemistry ,Biomedical Engineering ,Biophysics ,General Medicine ,Biotechnology - Published
- 2023
238. Fabrication of high power density paper-based microfluidic fuel cell using a stepped catalyst layer
- Author
-
Zhi Liu, Jicheng Ma, Kui Jiao, Qing Du, and Fuqiang Bai
- Subjects
Electrochemistry ,Biomedical Engineering ,Biophysics ,Biotechnology - Published
- 2023
239. Effects of adding paper-making sludge on yield and properties of extracted products from sewage sludge and enrichment of apatite inorganic phosphorus
- Author
-
Zongqi Chen, Shoumeng Yang, Lihui Zhang, and Feng Duan
- Subjects
Fuel Technology ,General Chemical Engineering ,Organic Chemistry ,Energy Engineering and Power Technology - Published
- 2023
240. Eco-friendly functional cellulose paper as a fire alarming via wireless warning transmission for indoor fireproofing
- Author
-
Xiaolu Li, José Sánchez del Río Sáez, Antonio Vázquez-López, Xiang Ao, Raquel Sánchez Díaz, and De-Yi Wang
- Subjects
Agronomy and Crop Science - Published
- 2023
241. Paper material coated with soybean residue nanocellulose waterproof agent and its application in food packaging
- Author
-
Peiyi Li, Miaomiao Zhou, Boxing Jian, Haozhe Lei, Ruiyan Liu, Xinyao Zhou, Xinping Li, Yun Wang, and Bingyao Zhou
- Subjects
Agronomy and Crop Science - Published
- 2023
242. Exploring greenhouse gas emissions pathways and stakeholder perspectives: In search of circular economy policy innovation for waste paper management and carbon neutrality in Hong Kong
- Author
-
Peixiu Chen, Meike Sauerwein, and Benjamin Steuer
- Subjects
Environmental Engineering ,General Medicine ,Management, Monitoring, Policy and Law ,Waste Management and Disposal - Published
- 2023
243. Emulsion polymerized styrene acrylic/nanocellulose composite coating to improve the strength and hydrophobicity of kraft paper
- Author
-
Abhay Shankar, Abdul Malik A.K., Ramanuj Narayan, and Arindam Chakrabarty
- Subjects
General Chemical Engineering ,Organic Chemistry ,Materials Chemistry ,Surfaces, Coatings and Films - Published
- 2023
244. Facile synthesis of amorphous nickel iron borate grown on carbon paper as stable electrode materials for promoted electrocatalytic urea oxidation
- Author
-
Abdulaziz M. Alsalman, Abdullah M. Al-Mayouf, Mahmoud Hezam, Saba A. Aladeemy, Zeyad Almutairi, Prabhakarn Arunachalam, and Mabrook S. Amer
- Subjects
Tafel equation ,Materials science ,chemistry.chemical_element ,General Chemistry ,Catalysis ,Amorphous solid ,Nickel ,chemistry.chemical_compound ,chemistry ,X-ray photoelectron spectroscopy ,Transmission electron microscopy ,Urea ,Boron ,Nuclear chemistry - Abstract
The development of greatly stable and cost-effective electrocatalysts for urea electro-oxidation reactions (UERs) is urgent and challenging for promoting urea removal in the wastewater and advanced energy conversion devices. We demonstrated that nickel-iron borate (NiFe-B) electrocatalysts supported on carbon paper (CP) for UERs through a one-pot solvothermal method. NiFe-B electrocatalysts were obtained with numerous Ni/Fe molar ratios in the precursors, and the physicochemical features of the NiFe-B were examined by X-ray diffraction, scanning and transmission electron microscope, and X-ray photoelectron spectroscopy. The optimized NiFe-B/CP exhibited a low onset potential (Eonset = 0.287 V vs. SCE) with a Tafel slope of 27.9 mV/dec on CP, demonstrating much greater performance UERs. Furthermore, the NiFe-B/CP catalysts have shown a superior activity for the UERs in alkaline solution and exhibit more than two-fold enhancement in activity than Ni-B. Facile, cost-effective fabrication and highly efficient urea oxidation create the NiFe-B electrodes as attractive materials for UERs.
- Published
- 2022
245. Clinical validation of a liquid chromatography-tandem mass spectrometry method for the quantification of calcineurin and mTOR inhibitors in dried matrix on paper discs
- Author
-
Ignacio Guillermo, Bressán, María Isabel, Giménez, and Susana Francisca, Llesuy
- Subjects
Medical Laboratory Technology ,Clinical Biochemistry ,Microbiology ,Spectroscopy - Abstract
Advances in liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) have enabled the quantification of immunosuppressants using microsampling techniques. In this context, dried matrix on paper discs (DMPD) could be a useful alternative to conventional venipuncture. Although analytical validation is necessary to establish the suitability of method performance, it is not sufficient to proceed with its implementation into routine clinical practice. Also necessary is that equivalence between sampling methods be demonstrated in a clinical validation study.To clinically validate a LC-MS/MS method for the quantification of tacrolimus, sirolimus, everolimus and cyclosporin A using DMPD.According to the recommendations of international guidelines, at least 40 whole blood (WB) and DMPD paired samples for each analyte were collected by skilled technicians and analyzed using LC-MS/MS. Results were evaluated in terms of statistical agreement and bias values at medical decision points.For all analytes, Passing-Bablok regression analysis revealed that confidence intervals (CIs) for slopes and intercepts included 1 and 0, respectively. It also showed that biases at medical decision points were not clinically relevant. No statistically significant differences between DMPD and WB were found using difference plots and agreement analysis. In this regard, CIs for bias estimators included 0, and more than 95% of the results fell within the limits of agreement.The feasibility of the clinical application of simultaneous quantification of tacrolimus, sirolimus, everolimus and cyclosporin A in DMPD was demonstrated. Results showed that this microsampling technique is interchangeable with conventional WB sampling when specimens are collected by trained personnel.
- Published
- 2022
246. Enhancement in properties of concrete by assessing bio-cement – Trial mix paper
- Author
-
T.V.S. Vara Lakshmi and R. Santhi Kala
- Subjects
010302 applied physics ,Cement ,Curing (food preservation) ,Materials science ,Precipitation (chemistry) ,02 engineering and technology ,General Medicine ,021001 nanoscience & nanotechnology ,01 natural sciences ,Permeability (earth sciences) ,Compressive strength ,Flexural strength ,Properties of concrete ,0103 physical sciences ,Composite material ,0210 nano-technology - Abstract
Micro-cracks are inherently present in concrete, leads to debilitation of structures. Methods used for managing micro-cracks have a certain degree of toxicity and also possesses certain drawbacks that made them not completely efficient. Bacterial technique when used in fresh concretes results in calcite precipitation in voids and consequently improves the strength and lowers permeability of concrete. Bio- cement is the combination of Bacillus pasteurii 5% and nutrients Urea, Calcium Lactate 95%. In this study by adding 0.5, 1, 1.5 and 2% Bio- cement by weight of cement and observed compressive strength, flexural strength values after 7 and 28 days of curing for M25 grade of concrete.
- Published
- 2023
247. A 3D origami paper-based analytical device combined with PVC membrane for colorimetric assay of heavy metal ions: Application to determination of Cu(II) in water samples
- Author
-
Hoda Sharifi, Javad Tashkhourian, and Bahram Hemmateenejad
- Subjects
Detection limit ,Analyte ,Chemistry ,Metal ions in aqueous solution ,010401 analytical chemistry ,Inorganic chemistry ,Microfluidics ,02 engineering and technology ,Paper based ,021001 nanoscience & nanotechnology ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Analytical Chemistry ,Membrane ,Reagent ,Environmental Chemistry ,Leaching (metallurgy) ,0210 nano-technology ,Spectroscopy - Abstract
Microfluidic paper-based analytical devices (μPADs) as a potentially powerful analytical platform have recently gained significant attention for on-site monitoring of heavy metal ions, which are one of the most significant environmental concern because of non-degradability and high toxicity. The commonly applied μPADs suffers from some defects, such as heterogeneous deposition of reagent, resulting in poor detection limits and low sensitivity. So, in this work, a three-dimensional origami μPAD combined with PVC Membrane was developed, which can manage problems of movement of colored products or leaching out the dye and leading to color heterogeneity in the detection zones. Furthermore, a waste layer was added to μPAD for loading of more amounts of the analyte, which results in improvement of detection limit. As a proof of concept, the μPAD was used for the analysis of Cu2+ ion. For this purpose, pyrocatechol violet and chrome azurol S as colorimetric reagents were doped into PVC membrane and injected in the detection zone. The proposed μPAD was presented good linearity in the ranges of 5.0–1400.0 and 5.0–200.0 mg L−1, and the limits of detections of 1.7 and 1.9 mg L−1 in presence of chrome azurol S and pyrocatechol violet, respectively.
- Published
- 2020
248. The preparation of graphene ink from the exfoliation of graphite in pullulan, chitosan and alginate for strain-sensitive paper
- Author
-
Kamal Yusoh, Nurul Farhana Abu Kasim, Wan Farhana W Idris, Abu Hannifa Abdullah, and Zulhelmi Ismail
- Subjects
Paper ,Materials science ,Alginates ,Sonication ,02 engineering and technology ,Biochemistry ,law.invention ,Chitosan ,03 medical and health sciences ,chemistry.chemical_compound ,Adsorption ,Structural Biology ,law ,Conductive ink ,Electric Impedance ,Graphite ,Glucans ,Molecular Biology ,030304 developmental biology ,0303 health sciences ,Graphene ,Pullulan ,General Medicine ,021001 nanoscience & nanotechnology ,Exfoliation joint ,chemistry ,Chemical engineering ,Ink ,Stress, Mechanical ,0210 nano-technology - Abstract
A sonication of graphite in polysaccharide (pullulan, chitosan and alginate) is one of the viable methods for the preparation of few-layer graphene. However, the effect of these adsorbed polysaccharides on the electrical performance of the produced graphene so far is not yet clear. In order to investigate the present effect of pullulan, chitosan and alginate on the electrical characteristic of resulted graphene, we have produced few-layer graphene using bath sonication of graphite in pullulan, chitosan and alginate medium for the application as electrical conductive ink in strain-sensitive. Data from the TEM reveals the appearance of folded few-layer graphene flakes after sonication for 150 min while the XPS data shows that the chitosan-based graphene possesses the highest carbon-oxygen ratio of 7.2 as compared to that of the pullulan and alginate-based graphene. By subjecting the produced graphene as the ink for paper-based strain sensor, we have discovered that the chitosan-graphene has the best resistivity value (1.66 × 10-3 Ω⋅cm) and demonstrate the highest sensitivity towards strain (GF: 18.6). This result interestingly implies the potential of the reported chitosan-based conductive ink as a strain-sensitive material for future food packaging.
- Published
- 2020
249. Anaerobic co-digestion of paper sludge: Feasibility of additional methane generation in mechanical–biological treatment plants
- Author
-
Fabian Gievers, Meike Walz, Kirsten Loewe, Christian Bienert, and Achim Loewen
- Subjects
Bioreactors ,Sewage ,Metals, Heavy ,Feasibility Studies ,Digestion ,Anaerobiosis ,Methane ,Waste Management and Disposal - Abstract
In this work, the feasibility of the anaerobic digestion of paper sludge as a co-substrate in anaerobic digestion mechanical-biological treatment (MBT) plants is investigated. In the first phase, the biochemical properties, biomethane potential (BMP), and pollutant contents of 20 different industrial paper sludges are determined. Following the general evaluation in the BMP tests, the second phase of the project involves the semi-continuous co-digestion of six paper sludges in continuous stirred reactors (CSTR). Paper sludges are categorized according to their origin within the pulp and paper mills: Deinking Sludge (DS), Primary Sludge (PS) and Biological Sludge (BS). The analysis of potentially inhibiting elements shows that the concentrations of chlororganic compounds, mineral oil and some heavy metals are highest in DS, while the mean heavy metal loads in all paper sludges are relatively low compared to other industrial sludges. Large differences in total solids (TS) and volatile solids (VS) contents are observed among the different paper sludges investigated, with DS having the highest TS due to the high inorganic contents. The BMP of the investigated sludges ranges from 90 to 355 NL CH
- Published
- 2022
250. Ready-to-use vertical flow paper device for instrument-free room temperature reverse transcription
- Author
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Thomas Michael Shiju, Chaturvedula Tripura, Pritam Saha, Arushi Mansingh, Venkatapathi Challa, Ira Bhatnagar, Narayana Nagesh, and Amit Asthana
- Subjects
Temperature ,Humans ,RNA ,Bioengineering ,Reverse Transcription ,General Medicine ,Nucleic Acid Amplification Techniques ,Molecular Biology ,Biotechnology - Abstract
Paper-based nucleic acid detection and diagnosis are currently gaining much interest in point-of-care (POC) applications. The major steps involved in any nucleic acid amplification testing (NAAT) based diagnostics are nucleic acid isolation, reverse transcription (RT) (in the case of RNA), amplification and detection. RT is an important step in quantifying the viral load in case of disease diagnosis as well as quantifying gene expression levels in other molecular studies. cDNA synthesis is routinely carried out using a thermal cycler, with the process requiring temperatures between 40ºC to 65ºC. Here we report for the first time an instrument-free RT, performed at room temperature on cellulose-based paper devices. cDNA synthesis on paper was confirmed by RT-PCR and Sanger sequencing of the PCR products. Purified RNA from varied sources such as cell lysate, tissue and blood were used to test the methodology. Synthetic hepatitis C virus (HCV) RNA and human blood RNA were used as proof-of-concept to demonstrate the use of these devices in diagnostic applications. Further, ready-to-use paper-based reverse transcription (PRT) devices have been developed, wherein only the RNA sample is added on the device and the cDNA can be eluted after 30 min of incubation at room temperature. The devices were found to be stable for 30 days at - 20ºC storage. The cellulose-based PRT devices are simple, time saving and user-friendly for a complete instrument-free cDNA synthesis at room temperature.
- Published
- 2022
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