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Introduced: Erythema infectious disease is a childhood infectious disease associated with a rash caused by parvovirus B19. The infection is especially dangerous for pregnant women. The disease can lead to intrauterine anemia and miscarriage, even when the pregnant woman did not have any clinical signs of infection. Aim of the study: The aim of the study was to assess the level of women's knowledge about erythema infectious and its importance in pregnancy. Materials and methods: The study conducted in May 2023 covered 150 women in various age groups. The research material was collected using an anonymous online questionnaire. The obtained results were analyzed and verified on the basis of scientific literature. Results: The percentage of respondents who had contact with erythema infectious is 64.7% and 64% correctly indicated parvovirus B19 as the etiological factor of the disease. 78% of respondents know that infection with erythema infectious is dangerous for pregnant women. 51.3% of respondents confirm that parvovirus B19 can cause fetal hydrops and 61.3% of women clearly indicate that even an asymptomatic course of infection in pregnant women can be a threat to the fetus. Conclusions: Women have basic knowledge about erythema infectious and its negative impact on pregnancy, but do not know details about complications and treatment. Women should be educated about the risk factors for the disease its symptoms and the effects of the disease. The aim is to minimize the risk of infection during pregnancy.

Rhesus-conflict is a pathological condition that manifests itself in the formation of antibodies against fetal erythrocytes in the body of pregnant woman due to the incompatibility of maternal and fetal Rh-factors. The main causes of morbidity and mortality in rhesus conflict are intrauterine hemolytic anemia, fetal hydrops, hemolytic neonatal disease. In addition, an important factor contributing to the increase in perinatal losses in this pathology is the high birth rate of extremely immature children. The reason for this is a preterm labor induction in case of a threat to the life of the fetus, as well as premature births associated with a variety of fetal manipulations. The number of cases of this pathology has declined dramatically throughout the world over the last decades, due to the widespread coverage of women at risk of immunization (anti-D - immunoglobulin). Unfortunately, in Ukraine this situation is not uncommon to this day. The article covers the main modern views on the causes, pathogenesis, course and prevention of immunological conflict associated with incompatibility of the Rh factor in terms of evidence-based medicine. The article describes the experience gained during recent years and attempts to unify the prognostic and preventive approaches in this area. Conclusions: 1. Rhesus-conflict remains a serious problem of domestic medicine with a significant contribution to perinatal loss. 2. Proper and timely anti-Rh immune prophylaxis among all non-immunized women can significantly reduce the incidence of severe disease in fetuses and newborns. 3. There are no remedies for Rhesus conflict. Treatment is subjected to severe hemolytic disease only that occurs before the fetal maturity. Intrauterine hemotransfusion allows prolonging such pregnancy and preventing antenatal fetal death.