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Results of the dynamic investigation of the endogenous intoxication nonspecific markers in 107 patients suffering choledocholithiasis were presented. Under the influence of enteral probe nutrition, using oligosized mixture Peptamen (Nestle), in patients of the main group the endogenous intoxication nonspecific markers normalization had occurred faster than in a control group.

Results of study of the endogenous intoxication severity (EI) in 107 patients for choledocholithiasis (CL) were presented. In complex of treatment the probe enteral nutrition (PEN) was applied. Diagnosis of EI according to cellular indexes of intoxication and the peptides level of the average molecular mass (PAMM) in blood for wavelengths 254 and 280 nm was conducted. There was established, that leukocytic index of intoxication, calculated according to formula Himich-Kostyuchenko, have strong correlational causation with index of PAMM and may be applied for diagnosis and control of efficacy of the EI correction in patients with CL. PEN with application of oligopeptide mixture "Peptamen" (Nestle) had promoted effective correction of EI, what have allowed to lower frequency of postoperative complications by 11% and to shorten the treatment duration of patients after operation by 4 days.