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Objectives:Our aim was to compare the refractive status and anterior segment parameters of patients with juvenile open-angle glaucoma (JOAG) and normal subjects.Materials and Methods:Twenty-five recently diagnosed cases of JOAG and 24 normal subjects were included in this prospective controlled clinical trial. Central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), axial length (AL), K1 and K2 keratometry, and white-to-white distance (WTW) measurements were performed with optical biometry (LenStar LS 900, Haag Streit Diagnostics). Spherical equivalent (SE) values and anterior segment parameters were statistically compared by chi-square, Kolmogorov- Smirnov, and independent samples t-tests.Results:The mean age of the 15 male and 10 female JOAG patients was 11.8±2.78 (8-18) years and the mean age of the 14 male and 10 female normal subjects was 11.58±3.04 (7-16) years (age: p=0.51; sex: p=0.18). Mean intraocular pressure in the JOAG group before treatment was 30.08±4.3 mmHg. The mean SE values of the JOAG and the control group were -1.94±1.86 (+2.35/-5.5) and -0.76±2.03 (+2.25/-4.85) diopters, respectively (p=0.048). JOAG patients had lower mean CCT values (p=0.016) and higher mean AL and ACD values (p=0.049 and p=0.016). There were no significant differences between the groups for LT, WTW, K1, or K2 (p=0.61; p=0.52; p=0.95; p=0.31 respectively).Conclusion:JOAG patients were found to be more myopic and have lower CCT and greater AL and ACD values than normal subjects. These anterior segment changes may be associated with myopia, which is common in JOAG.

Objective: To evaluate the corneal, conjunctival epithelial and overall thicknesses measured by anterior segment optical coherence tomography (OCT) in healthy population. Methods: This retrospective study included 134 eyes of 134 healthy individuals who were undergone a Cirrus HDOCT examination using the Anterior Segment 5 Line Raster protocol. Corneal, conjunctival epithelial and overall thicknesses were measured on OCT images. The average values of four OCT parameters were compared between sexes and among the six subgroups with respect to age. Results: The average corneal epithelial and overall thicknesses were 51.30±4.60 µm and 532.47±37.30 µm, respectively. The average conjunctival epithelial and overall thicknesses were 47.20±8.03 µm and 237.07±40.62 µm, respectively. All of the measurements were thicker in males compared to females, however the significant difference was found for only corneal epithelium (p=0.043). Using the Spearman correlation coefficient, central corneal and conjunctival epithelial thicknesses showed significant negative correlations with age (p=0.006, p=0.005, respectively) and refraction (p=0.040, p=0.033, respectively). Conclusion: Ocular surface parameters measured by anterior segment OCT were gender, age, and refractionrelated. Thus, further studies conducted to evaluate the corneal and conjunctival thicknesses should involve gender, age, and refraction-matched control groups. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate choroidal thickness in highly miyopic eyes and to correlate it with axial length, visual acuity, age and spherical equivalent. Materials and Methods: This study was composed of 21 eyes of 14 patients with high myopia (=6 diopters or axial lenght =26 mm) and 20 eyes of 12 healthy volunteers. Choroidal thicknesses were manually measured by enhanced depth imaging optical coherence tomography from the posterior edge of the retinal pigment epithelium to the choroid-scleral junction. Statistical analysis was performed. Results: The mean age of high myopia group was 39.8±6.4 years (range, 28 to 51 years) and the mean axial length was 29.3±2.3 mm (range, 26 to 32 mm). The mean choroidal thickness was 104.2±21.6 µm and was correlated negatively with axial length, age, refractive error and visual acuity. Statsitical analysis suggested that choroidal thickness decreased by 3.9 µm for each milimeter of axial length and by 6.03 µm for each myopic dioptre. Conclusions: In highly myopic eyes choroidal thickness is thinner than emetropic eyes and undergoes further thinning with increasing with axial length, spherical equivalent and age. Our results supports that choroidal abnormalities may play a role in the pathogenesis of myopic degenerations. [ABSTRACT FROM AUTHOR]

Purpose: To determine retinal nerve fiber layer thickness and its correlation with spherical equivalent and axial length in high myopic patients. Materials and Methods: The study includes 21 eyes of 12 high myopic (⩾6 diopter or axial length ⩾26 mm) patients and 20 eyes of 12 healthy volunteer. Retinal nerve fiber layers were measured from superior, inferior, temporal, nasal quadrants respectively by using spectral domain optical cohorence tomography. Mean RNFL thicknesses wre recorded. Statistical analysis was performed. Litmann formula was used for correction of axial length related ocular magnification effect. Results: The mean age and axial length in high myopia group were 39.8±6.4 years (range 28-58 years) and 29.3±2.3 mm (range 26 - 32 mm), respectively. RNFL thicknesses of high myopic eyes in superior, inferior, temporal and nasal quadrants were 116.7±5.1 μm, 115.4±5.3 μm, 80.1±12.4 μm and 68.3±8.5 μm, respectively. Mean RNFL thickness in high myopia and control groups were 97.8±6.4 μm and 114.3±5.7 μm , respectively. The mean RNFL thickness in high myopia group was found to be quite more thinner than emethropic control group. It was observed that as the axial length and spherical equivalent get increase, the mean RNFL thickness gets thinner. Conclusion: It is observed that the RNFL thickness values change in relation with the degree of myopia. That's why, while investigating the damage emanating from glaucoma, especially in myopic patients, these variabilities should be taken into consideration. [ABSTRACT FROM AUTHOR]

Purpose: To compare combined surgery and separate surgery in eyes coexisting with cataract and vitreoretinal pathology. Materials and Methods: 60 patients (61 eye) charts are reviewed retrospectively forming two groups; coexisting with cataract and vitreoretinal pathology which had combined or separate surgery between 2004-2011. The patients preoperative, postoperative 1'sth month and last visit best corrected visual acuity is registered in snellen test and translated to logMAR test. Patients preoperative and postoperative refractions spherical equivalent are recorded. Results: We inserted 30 eyeses of 30 patient which had combined surgery in the first group and 31 eyeses of 30 patients which had separate surgery in in second group. 1'sth grupes mean preoperative vision is 1.34±0.96 (3-0.8) logMAR, postoperative 1'sth month vision is 1.38±0.96 (3-0.8) logMAR and the last visit vision is 0.92±0.75 (3-0.8). 2'nd grupes mean preoperative vision is 1.48±0.87 (3-0.8) logMAR, postoperative 1'sth month vision is 0.81±0.86 (3-0.8) logMAR and the last visit vision is 0.69±0.81 (3-0.8) logMAR. There was no significant relation between two grups visions (p=0.055). In 1'sth grup 18 (60.0%) eyeses vision improved, 8 (26.7%) eyeses vision decreased, 4 (13.3%) eyses vision didn't changed at the last visit. In 2'nd grup 24 (80%) eyeses vision improved, 2 (6.7%) eyeses vision decreased, 4 (13.3%) eyses vision didn't changed at the last visit. Conclusion: Combined surgery procures early visual rehabilitation and protects the patient from the second cataract surgery. [ABSTRACT FROM AUTHOR]

Background: The aim of this study was to compare preop-erative and postoperative keratometric values in patients who had Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) surgery. Methods: Twenty five eyes of 25 patients who had undergone DSAEK surgery due to endothelial dysfunction were reviewed retrospectively. Refractive and keratometric measurements were recorded. Results: There were 11 (44%) female and 14 (56%) male patients. The mean age was 60.4±11.5 years (range 41-81). Nineteen eyes (76%) had bullous keratopathy, 4 eyes (16%) had Fuch's endothelial dystrophy and 2 eyes (8%) had corneal graft failure. The mean follow-up period was 25.4±9.2 months (6-45 months). The mean maximum keratometry (Kmax) was 43.82±1.59 Diopter (D) (range, 42.00-50.00 D) preoperatively. The mean Kmax was 44±1.7D (42.00-50.00 D) at the first control visit and 44.05±2.12 D (41.75-49.75 D) at the last control visit postoperatively. The mean keratometric astigmatism was 1.72±1.34 D preoperatively. The mean keratometric astigma-tismwas 1.69±1.27 D at the first month and 1.65±1.51Datthe last control visit. Conclusion: DSAEK surgery resulted in better outcomes, preserving anatomical integrity, causing minimal corneal keratometric changes, inducing minimal astigmatism with stable refractive values. [ABSTRACT FROM AUTHOR]