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Objective: Bloodstream infections (BSIs) remain a leading cause of morbidity and mortality. We aimed to evaluate the appropriateness of empiric antimicrobial treatment in patients with BSI and its effect on mortality and hospital stay. Methods: 100 BSI-diagnosed patients aged 18 and older were included in the study. Sociodemographic characteristics, clinical and microbiological data, empirically initiated treatments, time to appropriate treatment, 10th-day (early period) and hospital discharge mortality rates, and lengths of hospital stay were recorded. Data were analyzed using Pearson χ², Fisher's exact test, trend χ² test, and Mann-Whitney U test. Logistic regression assessed the impact on mortality, with p <0.05 considered statistically significant. Results: 51% of cases were female, and the median age was 64 (min-max=19-94). No significant difference was found between appropriate and inappropriate antibiotic treatment groups in age, sex, clinical severity, Charlson comorbidity index (CCI) scores, and microorganism distribution. However, multidrug-resistant organisms were significantly more common in the inappropriate empiric treatment group (p=0.001). Of all BSIs, 57% were hospital-acquired, and 43% were community-onset, with primary BSIs accounting for 55%. No significant difference was found between the groups in terms of where BSI was acquired and its source. Empiric treatment appropriateness was 57%, with resistance among microorganisms being the main factor in inappropriate treatment. Early period (10th-day) mortality was 26%, and hospital discharge mortality was 41%, with no significant association found between the empiric treatment, appropriateness, time to appropriate treatment, and mortality. However, inappropriate empiric treatment was signifi- cantly associated with higher hospital discharge mortality (p=0.033) in immunocompetent patients. Hospital stay was significantly shorter in the appropriate empiric treatment group compared to the inappropriate group (p=0.035). Conclusion: We did not find significant impact of the appropriateness of antimicrobial treatment and time to appropriate treatment on mortality but appropriate treatment significantly shortened hospital stays. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Uludag University Medical Faculty / Uludağ Üniversitesi Tıp Fakültesi Dergisi is the property of Journal of Uludag University Medical Faculty and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Uludag University Medical Faculty / Uludağ Üniversitesi Tıp Fakültesi Dergisi is the property of Journal of Uludag University Medical Faculty and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: Upper gastrointestinal bleeding (UGK) is one of the leading causes of emergency department admissions and hospitalizations. Various risk scores are used to predict the need for invasive treatment (endoscopic hemostasis, blood transfusion, surgical management), rebleeding, and mortality at the time of admission. Our study aims to compare the performance of preendoscopic Rockall (pRS), Glasgow-Blatchford bleeding (GBS), and AIMS-65 scores before endoscopy in predicting high-risk groups. Methods: Patients who were admitted to the emergency department between January 2015 and June 2016 and were diagnosed as non-variceal UGR after clinical, laboratory, and/or endoscopic evaluation were retrospectively screened. Demographic and clinical characteristics, laboratory values, scoring points, endoscopic intervention, and clinical course (blood transfusion, rebleeding, surgical management, death) were recorded. Results: 163 patients (79% male) with a median age of 57.2± 18.7 years were included in the study. To stop bleeding, endoscopic intervention was performed in 92 patients (56.4%) and surgical intervention was performed in 6 patients (3.7%). Rebleeding occurred in 9.2% of the patients (15 patients). 63.8% (104 patients) received a blood transfusion. The mortality rate was 2.5% (4 patients). AIMS-65 score was found to be superior to others in predicting mortality (AUROC= 0.892, p=0.007). GBS was found to be superior to others in predicting rebleeding, blood transfusion, and surgical management (AUROC=0.697, p=0.012; AUROC=0.778, p<0.001, and AUROC=0.851, p=0.004, respectively). pRS and AIMS-65 are similarly effective in predicting endoscopic intervention and are superior to GBS (AUROC=0.379, p=0.008 and AUROC=0.378, p=0.008, respectively). Conclusion: The AIMS-65 score was identified to be superior in predicting mortality. GBS score was identified to be superior in predicting rebleeding, blood transfusion, and the need for surgery. None of the scores were effective in predicting endoscopic intervention. The combined use of GBS and AIMS-65 can be useful in determining UGK with the high-risk group in the emergency department. [ABSTRACT FROM AUTHOR]

Objective: In this study, it was aimed to investigate the clinical features of COVID-19 patients hospitalized in our hospital and mortality-associated risk factors for patients who developed mortality. Material and Method: In this retrospective study, adult patients (over 18 years of age) who were hospitalized wtih a preliminary diagnosis of COVID-19 and SARS-CoV-2 PCR test positive between October 1, 2021 - March 31, 2022, were examined. Demographic data, comorbidities, SARS-CoV-2 vaccination history, laboratory and radiological data at first admission, need for intensive care, need for mechanical ventilation, and mortality rates during hospitalization were analyzed. The risk factors for mortality were investigated by multivariate logistic regression analysis. Results: The median age of the 266 patients included in the study was 72 (23-97), and 142 (53.4%) were male. There was at least one comorbidity in 238 (89.4%) of the patients. Mortality developed during hospitalization in 58 (21.8%) patients. In logistic regression analysis, age (p :0.022, OR :1.108, 95% CI :1.1015-1.211), CAD (p :0.005, OR :3.121, 95% CI :1.411-6.904), CRF (p :0.001, OR :5.674, 9%5 CI :1.956-16.463) was found to be an independent risk factor for mortality, and the number of doses of SARS-CoV-2 vaccine (p <0.001, OR :0.535, 95% CI :0.388-0.739) was found to be a protective factor from mortality. Conclusion: Significant mortality rates can be seen in the course of COVID-19. It is important to identify patients who may develop a poor prognosis in the early period. In our study, advanced age, CAD and CRF comorbidities, and the number of SARS-CoV-2 vaccine doses were determined as independent risk factors for mortality. [ABSTRACT FROM AUTHOR]

Copyright of Firat Universitesi Sağlik Bilimleri Tip Dergisi is the property of Firat Universitesiu, Saglik Bilimleri Enstitusu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Air pollution causes the death of millions of people every year. The increase in air temperatures with the effect of global warming increases the residence time of pollutants in the atmosphere. This situation increases the risk of exposure and death in terms of environmental and public health. Especially PM2.5 (fine particulate matter) is one of the main sources of upper respiratory diseases and deaths due to diseases. In this study, the effect of PM2.5 air pollution on adult (25+ years old) mortality in Zonguldak province was analyzed. 4 air quality measurement stations ((i) Catalagzı-Cumayanı, (ii) Catalagzı-Kuzyaka, (iii) Caycuma and (iv) Traffic) PM2.5 concentration data were evaluated on annual and seasonal basis. In the study conducted for 3 years (2020-2021 and 2022), it was determined that the estimated number of deaths attributed to air pollution reached its highest level in 2022 (an average of 927 people). [ABSTRACT FROM AUTHOR]

Copyright of Medical Journal of Ankara Training & Research Hospital is the property of Medical Journal of Ankara Training & Research Hospital and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Hip fracture is a condition frequently encountered in geriatric patients and is correlated with high postoperative mortality and morbidity. Numerous factors may impact mortality, but recent studies have focused on its correlation with inflammation. The neutrophil-to-platelet ratio has been evaluated as a systemic inflammation marker. The aim of our study was to examine the correlation between preoperative neutrophil-to-platelet ratio (NPR) values and postoperative one-year mortality in geriatric patients with hip fractures. Material and Method: In our retrospective, multicenter study, 50 patients over 65 years of age who had undergone hip fracture surgery under spinal anesthesia were examined. Patients’ preoperative neutrophil-to-platelet ratio values at the time of hospitalization, age, gender, American Society of Anesthesiologists scores, fracture types, comorbidities, durations of surgery, lengths of hospital stay, and survival in the postoperative one-year period were checked. Results: The mean age of all the patients was 85.44 ± 6.93 years. Of the patients, 60% were female (n = 30), and 40% were male (n = 20). The optimal cut-off value for preoperative neutrophil-to-platelet ratio was specified as 38.286. The length of hospital stay was 8.94 ± 3.05 in the deceased patients and 6.94 ± 2.63 days (p = 0.02) in the surviving group. The mortality rate was higher in men than in women (p = 0.01). Conclusion: A preoperative neutrophil-to-platelet ratio value over 38.286 is an indicator of postoperative one-year mortality in elderly hip fracture patients. Additionally, length of hospital stay and the male gender were revealed to be correlated with mortality.

Handgrip strength is a quick way to assess overall muscle strength. Low handgrip strength is an indicator of poor health. While handgrip strength is related with mortality and morbidity, for some parameters, handgrip strength is even a stronger predictor of health than chronological age alone. Handgrip strength is highly sexually dimorphic and has a high heritability. It is thought that this is an outcome of sexual selection and intrasexual competition in our evolutionary history. Some anthropological studies confirm this view, and it is claimed that there are relationships between grip strength and aggression, athletic performance and attractiveness, especially in men. The aim of this study is to review the relationship of diseases with handgrip strength in anthropological perspective and examine the idea that handgrip strength being a marker of biological fitness.

Copyright of Hamidiye Medical Journal is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Giriş: Dünya çapında yaşlı nüfusun sayısı ve oranı giderek artmakta olup, sepsis yaşlı hastalarda en sık görülen ölüm nedenlerinden biridir. Erken tedavi ve mortalitenin azaltılması açısından risk faktörleri ve kötü prognostik faktörlerin bilinmesi önemlidir. Bu çalışmada ileri yaşlı hastalarda sepsisin prognozunu etkileyen risk faktörlerinin değerlendirilmesi amaçlandı. Gereç ve Yöntem: Araştırma 2016-2023 yılları arasında ikinci basamak sağlık bir kuruluşunda retrospektif olarak gerçekleştirildi. Sepsis nedeniyle başvuran geriyatrik hastalar (>65 yaş) dahil edildi. Demografik veriler, tanı günündeki laboratuvar parametreleri, sepsis odağı, kökeni, etken mikroorganizmalar ve 28. gündeki mortalite kaydedildi. Bulgular: Çalışma döneminde 179 (%84) geriyatrik hasta sepsis nedeniyle başvurdu. Ortalama yaş 82 idi ve %44'ü erkekti. Yirmi sekiz günlük mortalite %49 idi. Ölen hastalarda hipertansiyon daha yaygındı (Tablo 2). Başvuru sırasında; ölen hastalarda nötrofil sayısı, kan üre nitrojeni ve sodyum değerleri daha yüksek, lenfosit, hemoglobin ve trombosit değerleri ise daha düşüktü (Tablo 3). Sepsis tanısı anında SIRS ve qSOFA skorları ölen hastalarda daha yüksekti (p<0,001). Septik şok oranı (%79,5'e karşı %33), yoğun bakım ihtiyacı (%99'a karşı %90), mekanik ventilasyon (%87,5'e karşı %55) ve vazopressör ihtiyacı (%55'e karşı %27,5), bakteriyemi oranı da (%26'ya %13,2) yaşayanlara göre daha yüksekti. Ölen hasta grubunda Gram-negatif mikroorganizmaların oranı, hayatta kalanlara göre istatistiksel olarak daha yüksekti (%63'e karşı %27; p<0,001). Kan kültüründe en sık izole edilen bakteri Klebsiella pneumoniae (%33); idrar kültürlerinde Escherichia coli (%35) ve balgam kültürlerinde Acinetobacter baumannii (%40) idi. Ölen hasta grubunda tedavinin 5. gününde, klinik yanıt oranı (%29), hayatta kalan hasta grubuna (%53) göre daha düşüktü (p=0,001) (Tablo 4). Mortalitenin en önemli belirleyicileri hipertansiyon odds oranı (OO): 2,39 (1,25-4,95), SIRS skoru OO: 1,86 (1,32-2,61) ve Gram-negatif bakteri sepsisi OO: 2,53 (1,22-5,22) idi. Sonuç: Ko-morbiditelerin bilinmesi, başvuru dönemindeki ağırlık skorları ve etken mikroorganizmaların öngörülerek uygun ampirik tedavinin başlanması ileri yaşlı hastalarda sağkalım açısından önem taşımaktadır. [ABSTRACT FROM AUTHOR]

Objective: Martality rates are high in patients who develop nosocomial infections (NI) in intensive care units (ICUs). In our study, we aimed to determine the risk factors for NI and NI-associated mortality in ICU patients Material and Method: Patients hospitalized in ICU in Dışkapı Yıldırım Beyazu Training and Research Hospital between 2017-2018 were evaluated retrospectively Patients aged 18 years and older, staying in ICU for at least 48 hours and not diagnosed with infection at the time of hospitalization were included in the study Results: A total of 200 patients were incluiled in the study During hospitalization period in ICU; 103 61.5%) patients developed NI and 97 (48.5%) patients did not develop NI. The mean age of patients was 71.6±15.5, 107 (53.5%) were female and the median hospitalization lenght was 8 B-144) days. When gender, age, Acute Physiology and Chronic Health Evaluation Il score (APACHE-II), Charlson Comorbidity Index, Glasgow Coma Score, presence of invasive mechanical ventilation (IMV), examined with multivariate analysis, it was determined that the length of stay in the intensive care unit increased the development of hospital infection by 1.14 times and the presence of central venous catheter by 3.5 times. When the risk factors for mortality in patients who developed I were examined by multivariate analysis, it was determined that a 1-unit increase in APACHE-11 score increased mortality 1.13 times, while IMV increased it 4,43 times. Conclusion: Patients hospitalized in the ICU have many risk factors for the development of NI. It is extremely important to determine the risk factors for NI and mortality in these patients, and compliance with infection control measures is extremely important. [ABSTRACT FROM AUTHOR]

Objective: The COVID-19 pandemic has caused significant morbidity and mortality and has challenged health systems worldwide. Immunosuppression is considered a risk factor for development of severe COVID-19. In this study, we aimed to determine the factors affecting morbidity and mortality in immunocompromised patients diagnosed with COVID-19. Methods: In this retrospective, cross-sectional study, laboratory findings and outcomes of 340 COVID-19 patients with secondary immunosuppression in a university hospital in Turkey from March 2020 to April 2022 were analyzed according to the 28-day clinical outcomes. Mortality-related factors were investigated in 3 patient groups with different forms of immunodeficiency: 1) malignancy (hematologic/solid), 2) organ transplantation, and 3) rheumatological diseases. Results: 172 (51%) of the patients were female, and the mean age was 61±15 years. A total of 122 (35.8%) patients died during hospitalization. The mortality rate (73.4%) in patients admitted to the intensive care unit (ICU) was significantly higher than those not admitted (p<0.001). The highest laboratory median values of urea, lactate dehydrogenase (LDH), D-dimer, ferritin, C-reactive protein (CRP), and fibrinogen values were found to be significantly higher, and the first measurement lymphocyte value was found to be considerably lower compared to the surviving patients (p<0.001) in the 28-day follow-up, ICU admission increased the mortality risk 13.6 (p<0.001) times. Anticoagulant treatment (p=0.029) and nasal oxygen support (p<0.001) led to a decrease in the risk of mortality. Conclusion: Immunocompromised patients are at risk for serious COVID-19 complications. LDH, D-dimer, CRP, and lymphocyte values can be used as markers to evaluate survival, and standard treatment is essential in immunosuppressive COVID-19 patients. [ABSTRACT FROM AUTHOR]

Objective: The cycle threshold value was used to predict disease severity, disease progression, determine transmissibility, and differentiate active viral replication from prolonged virus shedding. In this study, we aimed to evaluate the relationship between rRT-PCR cycle threshold and clinical course, mortality and laboratory parameters in COVID-19 patients. Methods: The patients included in the study were grouped according to how they were followed; as outpatients, service and intensive care unit patients. Data of age, gender, length of hospital stay, survival status and comorbidities of the patients were obtained from the hospital information system. In addition, CRP, ferritin, albumin, lactate dehydrogenase, procalcitonin and iron values of inpatients were reviewed retrospectively. Cycle threshold values of the patients were compared with each parameter separately. Results: 1339 patients with positive SARS-CoV-2 rRT-PCR test were included in the study. Of the patients, 774 (58%) were outpatients, 548 (41%) were in the ward, and 17 (1%) were in the intensive care unit. No significant difference was found between any of the groups when the cycle threshold values of the groups were compared statistically. Fifty (3.7%) of the patients included in the study died. Cycle threshold values of deceased patients were found to be significantly lower than those who survived (p=0.019). 306 (22.8%) of the patients had comorbidities. When the cycle threshold values of patients with and without comorbid disease were compared, no significant difference was found between any of the groups (p=0.850). In addition, no significant correlation was found between the length of hospital stay, age, CRP, LDH, ferritin, procalcitonin, albumin and iron values and the cycle threshold value. Conclusion: In conclusion, we did not find a significant difference between the cycle threshold values of outpatients, ward patients and intensive care patients. No significant correlation was found between the laboratory parameters, length of hospital stay and age, and the cycle threshold: however, deceased patients were found to have lower cycle thresholds than surviving patients. [ABSTRACT FROM AUTHOR]

Objective: We aimed to evaluate risk factors for bacteremia and mortality in patients with nosocomial Acinetobacter bacteremia in a university hospital's Anesthesia and Reanimation Intensive Care Unit (ICU) between 2013-2016. Methods: This study was designed as a retrospective case-control study; the case group consisted of patients older than 18 years, with Acinetobacter species growth in blood cultures taken 48 hours after hospitalization, with clinical bacteremia findings, followed until death or at least 30 days after culture. Patients in the control group consisted of cases without Acinetobacter bacteremia and showed similar characteristics to the case group. Patients were evaluated regarding demographic characteristics, underlying diseases, carbapenem use before blood culture was taken, appropriate empirical treatment, 30-day mortality, nutritional status, Pittsburgh Bacteremia Score (PBS), and interventional procedures. Results: Among case and control groups each consisting of 51 patients, carbapenem use (63.2% and 34.8%, respectively, odds ratio (OR)=3.67; 95% confidence interval (CI)=1.49-9.04, p=0.005) and chest tube placement (23.5% and 7.8%, respectively, OR=7.31; 95% CI=1.43-37.22, p=0.005) were independent risk factors for Acinetobacter bacteremia. Among cases with or without mortality in the case group, there was a significant difference in terms of endotracheal intubation (100%, 76.9%, respectively, p=0.023), PBS (6.6±1.08, 5.0±2.29, respectively, p=0.003), nutritional status (total parenteral nutrition [TPN] or enteral nutrition +TPN) (%28, %0 and %72, %100, respectively, p=0.004) and hypertension (HT) (%52, %19.2, respectively, p=0.03) and also HT [52% and 19.2%, respectively, OR=4.61; 95% CI=1.08-19.57, p=0.038], inappropriate empirical therapy [69.6% and 30.8%, respectively, OR=6.46; 95% CI=1.55-26.94, p=0.01] and albumin level [2.32±0.50 and 2.57±0.44 g/dL, respectively, OR=0.196; 95% CI=0.045-0.847, p=0.029] were independent mortality risk factors. Conclusion: Previous carbapenem use and chest tube insertion are important risk factors for Acinetobacter bacteremia in ICU. Inappropriate empirical treatment, HT, and low albumin levels are important mortality risk factors in Acinetobacter bacteremia in ICU. High PBS scores should be carefully evaluated for mortal Acinetobacter bacteremia. [ABSTRACT FROM AUTHOR]

Copyright of Medical Journal of Ankara Training & Research Hospital is the property of Medical Journal of Ankara Training & Research Hospital and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ege Journal of Medicine is the property of Ege University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ankara University Faculty of Medicine / Ankara Üniversitesi Tip Fakültesi Mecmuasi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Legal Medicine / Adli Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Our study aimed to investigate whether primarily hemostasis parameters and secondarily demographic, clinical, and laboratory values could predict the mortality of critically ill Coronavirus Disease 2019 (COVID-19) patients. Methods: We retrospectively examined 180 laboratory-confirmed adult intensive care unit (ICU) patients with COVID-19. A total of 145 patients with complete records were included in the study. The patients were divided into two groups: deceased (n=58) and discharged (n=87). The demographic and clinical characteristics of the two groups, use of vasopressor therapy, requirement for invasive mechanical ventilation (IMV), Acute Physiology and Chronic Health Evaluation II (APACHE II) score, duration of ICU stay, and the relationship between laboratory values on ICU admission and mortality were evaluated using cutoff values. Results: Among hemostatic parameters, only D-dimer>1.08 mg L-1 was found to be a significant predictor of mortality (p=0.04), while platelet, prothrombin time (PT), activated partial thromboplastin time (aPTT), International Normalized Ratio (INR) and fibrinogen values were not significantly associated with mortality (p>0.05). In addition, age >76 years, hypertension (HT), need for IMV, APACHE II score >23, procalcitonin (PCT) >0.21 μg L-1, lymphocytes <0.4 109 L-1, interleukin 6 (IL-6) >93 pg mL-1 were found to be predictors of mortality (p<0.05). Neutrophil and C-reactive protein (CRP) values were not significantly associated with mortality (p>0.05). Conclusion: Our study determined that advanced age, HT, high APACHE II score, requirement for IMV, vasopressor therapy, PCT, lymphocyte count, IL-6, and D-dimer levels could serve as predictors of mortality. Identifying predictors of mortality in COVID-19 is valuable for early recognition of disease progression and management of potential complications. [ABSTRACT FROM AUTHOR]

Objective: Routine laboratory parameters such as C-reactive protein (CRP), procalcitonin, ferritin, d-dimer are used to estimate the clinical severity and mortality of Coronavirus disease 2019 (COVID-19). Because of the limited specificity of these parameters and their variability between patients, more specific parameters are needed. It is thought that there may be a relationship between uric acid levels and the severity and mortality of COVID-19. In this study, we aimed to retrospectively investigate the relationship between daily serum uric acid measurements in the first 10 days of follow-up in the intensive care unit (ICU) and the need for invasive mechanical ventilation (IMV) and mortality. Methods: With the approval of the ethics committee, 151 eligible patients were screened through the ICU patient records and routine laboratory data on the computer. Serum uric acid measurements, demographic and clinical characteristics, IMV needs and mortality rates at the first admission to the hospital and in the first 10 days in the ICU were recorded retrospectively. Results: In the analysis, rate of IMV was 60.3% and mortality was 53.6%. No significant correlation was found between the uric acid levels measured at the time of first hospitalization and in the ICU follow-up and the need for IMV. In the comparison between deceased and survived patient groups; the uric acid levels were found to be higher on the 3rd and 4th days of the ICU in the deceased group than in the survivors (p=0.023, p=0.037, respectively). Conclusion: The increase in uric acid levels on the 3rd and 4th days in COVID-19 patients requiring ICU admission seems to be significant in the estimation of mortality. Serum uric acid level can be a useful parameter in determining the prognosis in the ICU follow-up of this group patients. [ABSTRACT FROM AUTHOR]

Copyright of MN Cardiology / MN Kardiyoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of MN Cardiology / MN Kardiyoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background and Aim: Predicting high-risk patients is crucial in acute myocardial infarction (AMI). We aimed to investigate whether the leukoglycemic index (LGI) has a unique ability and to compare it with other inflammatory parameters in predicting in-hospital mortality in AMI. Methods: In this single-center study, we retrospectively analyzed all AMI patients hospitalized and followed by a single operator. Patients were divided into two according to in-hospital outcomes. Other inflammatory parameters (systemic immune-inflammatory index, platelet-lymphocyte ratio, neutrophil-lymphocyte ratio, triglyceride-HDL ratio, and LDL-HDL ratio), C-reactive protein (CRP), and LGI were calculated according to previously described criteria. Univariable and multivariable logistic regression analyses were used to find independent predictors. The receiver operating characteristic (ROC) curve was used to find the cut-off point of LGI and other parameters in predicting mortality. Results: A total of 304 patients with AMI were included in the study. The mean age was 62.18±11.89 and 74 (24.3%) of patients were female. The total death rate was 19 (6.3%). In univariate variable analysis, LGI was found as a significant predictor of mortality (p

Aim: COVID-19 can cause clinical pictures ranging from asymptomatic to severe respiratory failure and sudden death. The severity of the disease varies depending on many factors such as comorbidity, vaccination status, as well as demographic characteristics such as age and gender. In this study, it was aimed to investigate the independent risk factors that have an effect on mortality in COVID-19 patients. Materials and Methods: In the study, records of 140 patients with a diagnosis of COVID-19 followed in the intensive care unit between 01.01.2021 and 01.01.2022 were examined. Demographic characteristics such as age and gender, comorbidity, vaccination status and clinical course of the patient were investigated and recorded. Results: In our study, a statistically significant difference was found between mortality and age, and the number of days of total invasive/noninvasive mechanical ventilation support (p=0.01, p=0.25, p

Objective: Acute kidney injury (AKI) has been reported in patients with COVID-19 pneumonia and associated with higher mortality. Our study aimed to determine the relationship of eGFR during admission to the intensive care unit with mortality and clinical outcomes in the elderly COVID-19 patients. Material and Method: This study in which the elderly patients were included was retrospectively performed in a single-center intensive care unit (ICU). Results: A total of 152 patients including 75 female and 77 male patients were included in the study. Mean age of the patients was 74.3±7.3 years. The number of patients was 92 (60.5%) in eGFR Stage 1-2, 15 (9.9%) in Stage 3a, 26 (17.1%) in Stage 3b, and 19 (12.5%) in Stage 4-5. The rate of patients who received invasive mechanical ventilation was 40.8% and hospital mortality rate was 48.7%. According to the multivariate logistic regression analysis, eGFR, LDH, Charlson score, and duration of stay in the intensive care unit were effective on mortality. Compared to eGFR Stage 1-2 patients, the mortality risk was 4.836 times higher in Stage 3a patients, 12.233 times higher in Stage 3b patients and 10.242 times higher in Stage 4-5 patients. Conclusion: Our results revealed that COVID-19 patients’ eGFR during admission to the intensive care unit, LDH, Charlson score, and duration of stay in the intensive care unit were effective on mortality.

Objective: Cardiopulmonary arrest is the condition of insufficient oxygen delivery to tissues as a result of sudden cessation of circulatory and respiratory functions. This study aimed to investigate the causes of arrest in patients admitted with cardiopulmonary arrest and the effect of initial cardiac rhythm on patient survival. Material and Methods: Out of 1126 patients who had an in-hospital and out-of-hospital cardiac arrest and were admitted to our emergency department, 1009 patients were included in this retrospective study following the exclusion criteria. In addition to the demographic characteristics of patients, their initial rhythms and mortality states were assessed. Results: There was a significant relationship between patients’ clinical outcomes and initial cardiac rhythms (p

Aim: The incidence of adverse postoperative outcomes in surgeries for femur fractures is high and is associated with malnutrition. In this study, it was aimed to determine the independent factors for 6-month survival in patients with femur fracture and to evaluate the predictive value of the prognostic nutrition index (PNI). Material and Method: One hundred and sixteen patients operated on only for femoral fracture were divided into survival and non-survival groups according to mortality.Demographic characteristics of the patients, operation data, fracture sites, need for intensive care unit and length of stay, postoperative hospital stay, and preoperative laboratory values, prognostic nutrition indices and mortality were evaluated. Results: Twenty-six (22.4%) of 116 patients who were operated for femoral fracture resulted in 6-month mortality. CRP, albumin, prealbumin, crp/albumin ratio and PNI values at admission were independent risk factors for postoperative mortality (p=0.014, p

Objective: We aimed to determine the main demographic features of COVID-19, reveal the clinical differences to patients in other countries, evaluate severe adverse effects in terms of number and types of comorbidities, and provide information about prognosis possibilities. Materials and Methods: Patients’ records, followed at Sakarya University Hospital between late March 2020 and late April 2020 with a diagnosis of COVID-19, were evaluated for this study. Demographic features were noted retrospectively with records, and data were recorded in the MS Excel program for analysis with SPSS. Statistical significance was set at p lt; 0.05. Results: The records of 1443 cases, 704 (48.8%) women and 739 (51.2%) men, a mean age of 44.98 ± 18.72, were examined retrospectively. Among them, 9.9% were medical staff, 1.8% had a history of travel abroad, and 1.1% were pregnant. Radiological findings of 59.4% of our polymerase chain reaction (PCR) positive patients were compatible with COVID. The mean length of hospital stay was 4.5 days. Frequent comorbidities were hypertension, diabetes (DM), and ischemic heart disease. Eighty (5.5%) patients treated in intensive care (ICU) died. Conclusion: Based on the data of 1443 patients, the mean length of hospitalization of COVID-19 patients was 4.5 days, or followed up in intensive care, having DM and a long period of hospitalization, which increased mortality risk. None of the outpatients died.

Aim: Systemic immune-inflammation (SII) index may provide more promising prognostic information in patients with cancer surgery. However, to the best of our knowledge, the prognostic value of SII index in patients with pancreatic cancer who underwent pancreaticoduodenectomy has not been studied. Thus, this study aimed to evaluate and compare the prognostic value of SII index in patients with pancreatic cancer who underwent pancreaticoduodenectomy. Materials and Methods: All patients over 18 years-old that underwent successful pancreaticoduodenectomy due to pancreatic cancer between February 20, 2019 and June 30, 2021 at Ankara City Hospital Department of General Surgery were included. The main predictor of interest was SII index which was measured by neutrophil*platelet / lymphocyte count. The main outcome of the study was long-term all-cause mortality. Results: A total of 223 patients were included in the current study. Multivariable cox regression analysis revealed that history of congestive heart failure [HR (95%CI): 3.682 (1.140-11.892)], and SII index [HR (95%CI): 1.001 (1.001-1.001)] were independently associated with all cause long-term mortality. The accuracy of predicting mortality for SII index was assessed by the area under the ROC curve which was = 0.77. A higher value of 1305 of SII index was found with 76% sensitivity and 67% specificity for predicting all-cause long-term mortality. Conclusions: The results of the study suggest that measurement of the SII index, an easily available and relatively cheap marker, is an independent predictor of long-term survival after pancreaticoduodenectomy in patients with pancreatic cancer.

Bu çalışma iki 5-(3'-amino-4'-arilazo-1H-pirazol-5'-ilazo) barbitürik asit boyasının (Boya 1 ve Boya 2) ekotoksikolojik çalışmalarda model organizma olarak bilinen Chironomus riparius (Diptera: Chironomidae) üzerindeki mortalite etkisinin ve akut toksisitesinin incelenmesi amacıyla yapılmıştır. Detaylı mortalite değerlendirmelerinden sonra Boya 2’nin organizmalar üzerinde Boya 1’e kıyasla daha fazla mortalite etkisine sebep olma potansiyeline sahip olduğu ve sucul ekosistemlerde yüksek konsantrasyonlarda uzun süreli bulunmasının bu ekosistemler için kayda değer bir tehdit oluşturabileceği sonucuna varılmıştır. Gerçekleştirilen toksisite sınıflandırmasında Boya 1’in, 24 ve 48 saat maruziyetlerde pratikte toksik değilken 72 ve 96 saat maruziyetlerde hafif derecede toksik olduğu, Boya 2’nin ise 24 saat maruziyette pratikte toksik değilken 48, 72 ve 96 saat maruziyetlerde hafif derecede toksik olduğu bulunmuştur. Mortalite etkisi ve toksisitedeki bu farklılıkların boya yapısında bulunan sübstitüentlerin farklı olmasından kaynaklanabileceği söylenebilir. Bu çalışma, yapısında metoksi ve metil grubu içeren azo boyaların (sırasıyla Boya 1 ve Boya 2) C. riparius üzerindeki mortalite etkisi ve akut toksisitesi ile ilgili önemli bilgiler sunmaktadır. Ancak daha kapsamlı ekotoksikolojik değerlendirmeler yapabilmek için bu ve benzeri azo boyaların ve bozunma ürünlerinin farklı organizmalar üzerindeki etkilerinin ve etki mekanizmalarının moleküler düzeyde incelendiği ve sucul ortamlardaki gerçek konsantrasyonlarının belirlendiği daha ileri çalışmalara ihtiyaç olduğu bir gerçektir.

Copyright of Mersin Üniversitesi sağlık Bilimleri Dergisi is the property of Mersin University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Amaç: 2019 aralık ayında başlayan Sars-Cov-2 adı verilen koronavirüs ailesine ait olan koronavirüs nedeniyle mart 2020 ayında tüm dünyada pandemi ilan edildi ve virüsün yol açtığı hastalık Covid-19 olarak anılmaya başlandı. Yaklaşık 176.000.000 kişiyi etkileyen pandemide 12/06/21 tarihi ile 3.500.000 dan fazla insanın vefat ettiği bildirilmiştir. Hipertansiyon tanısı olan hastalarda Covid-19 hastalarında ölüm oranlarının, hastane yatışlarının ve gelişen diğer komorbiditelerin daha fazla olduğu bilinmektedir. CRP, fibrinojen, D-dimer gibi laboratuvar değerlerinin Covid-19 için hastalık ilerleyişini belirlemede önemli olduğu da bilinmektedir. Bu çalışmamızda kliniğimizde Covid-19 nedenli takip edilen hipertansiyon tanısı olan hastaların hastane başvurusu anında bakılan Fibrinojen, Crp, D-dimer gibi Covid-19 için hastalık progresyonu belirteçlerinin hipertansiyonu olmayan hastalara kıyasla farklı olup olmadığı ve hipertansif Covid-19 hastalarında hastalık gidişatını belirlemek için bu parametrelerin kullanımının klinik fayda sağlayıp sağlamadığını belirlemeyi amaçladık Gereç ve Yöntem: İç hastalıkları kliniği servis ve yoğun bakımlarında 15/03/2020 ile 15/01/2021 tarihleri arasında Covid-19 nedenli takip edilen 590 hastanın verileri geriye dönük olarak incelendi. Hastaların yaşı cinsiyeti gibi demografik verileri ile beraber laboratuvar değerleri hastane otomasyon sisteminden tarandı. Veriler SPSS programına kaydedildi ve istatistiksel analizler yapıldı. Hastalar ölüm ve şifa sağlanan hastalar olarak 2 grupta incelendi. Bulgular: Hipertansiyonu olan hastaların ortalama yaşlarına bakıldığında 69,77±17,5 (n:310) iken hipertansiyonu olmayan hastaların yaş ortalaması 61,04±10,6 (n:280) olarak saptandı (p:0,000). Hipertansiyonu olan hastalarda D-dimer düzeylerine bakldığında 1270 (37-20200) n:295 ugFEU/L iken hipertansiyonu olmayan hastalarda 875(4-38800) n:266 (p:0,009) olarak görülmüştür. Fibrinojen düzeyleri ise hipertansif olan hastalarda 434,6±143,9 mg/dl n:279 iken hipertansif olmayan hastalarda 403,6±135,7 mg/dl n:240 (p:0,012) olarak saptanmıştır. Sonuç: Hipertansiyon tanısı olan Covid-19 hastalarında yüksek fibrinojen ve D-dimer düzeyleri kötü prognostik faktör olarak değerlendirilebilir.

Objective: We aimed to investigate whether hemoglobin levels in COVID-19 patients can serve as a valuable predictor of mortality. Material and Method: This retrospective study included 156 COVID-19 cases who were admitted to the intensive care unit (ICU), demographic characteristics, clinical data, and laboratory findings were recorded. Results: There are no significant differences in mean age, gender ratio, comorbidities, symptoms, mean APACHE-2, and SOFA values upon admission observed between the anemic and normal groups. The normal hemoglobin (Hgb) group’s mean lymphocyte and lactate values were statistically high(p

Aim: Obesity is a known risk factor for cardiovascular diseases. However, there are also studies showing that increased body mass index is unexpectedly protective in myocardial infarction. More studies are needed to elucidate this situation, known as the obesity paradox. This study was conducted to investigate the relationship between waist circumference and mortality and morbidity in acute ST elevated myocardial infarct (STEMI). Material and Method: This is a prospective and observational study. Patients diagnosed with STEMI on electrocardiography (ECG) were included in the study. Immediately after the exhalation, waist circumference (WC) was measured on a horizontal plane at a point equidistant from the lowest floating rib and the upper border of the iliac crest. The role of waist circumference in the development of mortality and major cardiac events within 1 month was evaluated. Results: A total of 106 patients admitted to the emergency department with STEMI were included in the study. While increased waist circumference was associated with mortality, it was insignificant in terms of major adverse cardiovascular event (MACE) development. Low BMI is significant in terms of decreased mortality and MACE. Conclusions: The use of WC as an indicator of body fat ratio rather than weight in STEMI may be more valuable in the evaluation of mortality and MACE.

Purpose: The aim of this study is to investigate the power of disease severity scores to predict the development of Severe Acute Pancreatitis (SAP) and mortality in the early period over 65 years old diagnosed with acute pancreatitis in the emergency department. Materials and Methods: We calculated RANSON (on admission) and Computed Tomography Severity Index (CTSI) in addition to Bedside Index for Severity in Acute Pancreatitis (BISAP) score on admission to the emergency department. Results: One hundred and sixty patients (46.9% over 80 years of age) were included in the study. We observed statistically higher length of hospitalization, longer duration of stay in the intensive care unit, SAP and higher mortality in patients over 80 years of age. When we examined the ROC curve, we determined that the AUC values of the BISAP score were highest in both SAP and mortality estimation (AUC: 0.911, 95% CI 0.861-0.962; AUC: 0.918, 95% CI 0.864-0.9722, respectively). Binary logistic analysis indicated a 4.7-fold increased risk for SAP and a 12.3-fold increased mortality for each unit increase in BISAP score value. Conclusion: BISAP may be a good predictor for SAP and mortality estimation on admission to the emergency department in patients over 65 years of age with acute pancreatitis.

Purpose: There are not enough studies evaluating the change in electrolytes and hormones in patients with sepsis. The aim of our study is to evaluate the relationship between the changes in serum calcium (Ca), magnesium (Mg), phosphorus (P), 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) levels and mortality in patients with sepsis. Materials and Methods: Our study was conducted on patients with sepsis who were hospitalized in the intensive care unit (ICU) between October 2017 and January 2019. The levels of Ca, Mg, P, 25(OH)D and PTH, together with demographic and clinical characteristics of non-survivor and survivor patients, were compared. Results: A total of 225 patients were enrolled into the study. Of the 225 patients, 94 patients (41.2%) died and 131 patients (58.8%) were discharged. PTH and P levels were found to be significantly higher, and 25(OH)D, Ca, and Mg levels were significantly lower in non-survivor patients than in survivor patients. Conclusions: During sepsis, the change in Ca metabolism which is in a delicate balance, in the direction of hypocalcemia, hypomagnesemia, hyperphosphatemia, low 25(OH)D and high PTH were found to be associated with mortality.

Objectives: Acute limb threatening ischemia (ALTI) is one of the most widely seen emergent vascular interventions, and is highly associated with cardiovascular mortality and amputations. Despite successful endovascular treatment (EVT) strategies and surgical interventions mortality and morbidity rates still remain higher in patients with ALTI. In this study, we aimed to investigate the long term clinical outcomes which are amputation-free survival and mortality, in patients with ALTI who treated either with EVT or surgical embolectomy. Methods: Our study enrolled 86 consecutive patients who diagnosed with ALTI in our hospital retrospectively in between 2016-2020. The accurate diagnosis of ALTI was made by using color doppler ultrasonography or computed tomography angiography. Patients with acute infection who need antibiotics, chronic inflammatory disease, end-stage hepatic impairment, and malignancy were not included. Patients were divided into two groups as those who were treated with surgical method (group 1) and those who were revascularized by endovascular methods (group 2). Results: The mean follow-up period was 19 months (1-26). All-cause mortality and amputation rates of patients in surgery group and EVT group were statistically similar (14,3% vs. 27,3%, p:0,139 and 14,3% vs. 9,1%, p: 0,453 respectively). Kaplan-Meier survival analysis showed no significant difference in between EVT and surgery group in term of all-cause mortality and amputation. (log-rank p = 0.649). In multivariate logistic regression analysis, Rutherford stage, congestive heart failure and CRP/albumin ratio (CAR) was found to be an independent predictor of amputation and all-cause mortality even after adjusting for other confounding risk factors. Conclusions: In our study, we observed that EVT and surgical embolectomy had similar long-term outcomes in patients with acute limb threatening ischemia. We also observed that Rutherford clinical stage, congestive heart failure and high CAR may be an independent predictor of mortality and amputation. This data needs to be supported by larger and prospective studies. [ABSTRACT FROM AUTHOR]

Objective: In the early stages of the worldwide coronavirus disease 2019 (COVID-19) pandemic, there aren’t many secondary intensive care unit publications. In our study, it was aimed to calculate the mortality rate and to determine the factors affecting mortality by retrospectively evaluating the data of COVID-19 patients hospitalized in a secondary intensive care unit. Methods: The files and records of patients aged 18 years and older who were positive for reverse transcriptase-polymerase chain reaction and followed in the secondary COVID-19 intensive care unit between January 2020 and July 2021, and their records in the hospital information system, were evaluated retrospectively. Demographic data, laboratory parameters, Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and clinical data of the patients were recorded. The data of living and deceased patients were compared. Regression analysis was performed for data with risk factors. Results: Archive records of a total of 227 patients were reviewed. The all cause mortality rate was 53.3%, and the median length of stay in the intensive care unit was 5 years. There was a significant difference in age (p<0.001), need for invasive mechanical ventilation (p<0.001), hospitalization saturation (p=0.016), ferritin (p<0.001), D-Dimer p(<0.001), APACHE II (p<0.001) and SOFA (p<0.001) scores between the living and deceased patient groups. Conclusion: Due to the increased number of patients and workload at the beginning of the COVID-19 pandemic, patient follow-up was carried out under difficult conditions in all intensive care units, especially in the secondary care units. In this period, we think that easily accessible biomarkers that can be used to predict mortality in secondary intensive care units may play a role in planning the treatment and referral processes of patients, and may have positive effects on patient outcomes by using the facilities more efficiently. [ABSTRACT FROM AUTHOR]

Objective: We aimed to compare laboratory and outcome of the patients who were hospitalized in the intensive care unit with the diagnosis of Coronavirus Disease-19 (COVID-19) and transfused convalescent plasma based on timing of treatment. Methods: Patients administered 200 mL of convalescent plasma were analysed retrospectively. Based on symptoms’ onset, patients were divided into two groups as early (≤ 7 days) and late (> 7 days) plasma treatment groups. Patients’ characteristics, comorbidities, treatments, laboratory (pre-transfusion, day 1 and day 3 after transfusion) and outcome were evaluated according to groups. Results: A total of 152 patients matched criteria. There was no difference between the early (n=82) and late (n=70) treatment groups in terms of demographic characteristics, comorbidities, treatments, outcomes. Ferritin levels were higher in the early treatment group than in the late treatment group on before transfusion and day 1 (p=0.023, p=0.015). C reactive protein value was lower in the late treatment group on day 3 (p=0.011). Comparing the rate of change between day 1 and day 3 of treatment, it was observed that the changes in ferritin and fibrinogen values were higher in the late group than in the early group (p=0.014, p=0.049). There was no difference between the groups in other laboratory values and outcome. Conclusion: In our study, we observed that the timing of convalescent plasma had no significant effect on outcome. However, more evidence was needed to prove the difference in laboratory results. [ABSTRACT FROM AUTHOR]

Copyright of Bosphorus Medical Journal / Boğaziçi Tıp Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Upper gastrointestinal system (UGIS) bleeding is a life-threatening abdominal emergency. Numerous scoring systems have been developed to identify patients who may develop mortality due to UGIS bleeding. We aimed to determine the effectiveness of the Glasgow Blatchford Score (GBS), Rockall score (RS), and AIMS 65 score in predicting the length of hospital stay, re-bleeding, and transfusion need. Material and Methods: It was carried out retrospectively by recording the parameters and clinical scoring systems collected from the archive files and epicrisis information of the patients with the pre-diagnosis of UGIS hemorrhage. Results: Sixty-three (67.7%) of 93 patients were male. Four patients (4.3%) needed intensive care, and in-hospital mortality occurred in 4 (4.3%) patients. Mortality was observed in 7 patients (7.5%), and recurrent UGIS bleeding was observed in six patients (6.5%). A statistically significant difference was found in AIMS 65 and Rockall scores in predicting -intensive care needs (p

Objective: The aim of the present study is to investigate whether the high sensitive troponin-I (HsTrop-I) and C-reactive protein (CRP) level that measured on admission is an independent predictor of mortality in patients with coronavirus disease 2019 (COVID-19). Materials and Methods: In this retrospective cohort study, a total of 175 consecutive patients with confirmed COVID-19 cases were screened from November 01, 2020 to January 31, 2021. Finally, 137 eligible patients were enrolled in to the study. Data of patients were recorded from the electronic medical records and National health data registry. Results: Mean age of study population was 49.7 ± 14.8 year and 88 (64.2%) patients were female. A HsTrop-I level ≥21.6 pg/ml measured on admission had a 86% sensitivity and 88% specificity in predicting mortality. The CRP level ≥80.8 mg/l on admission predicted mortality with 86% sensitivity and 95% specificity in patients with COVID-19. In the multivariate analyzes, HsTrop-I (odds ratio (OR) 1.124, 95% confidence interval (CI) 1.025–1.232; p=0.013) and CRP (OR 1.060, 95% CI 1.021–1.100; p=0.002) on admission were independent predictors of mortality in patients with COVID-19. Conclusion: HsTrop-I and CRP levels on admission which are easily measurable laboratory data were independent predictors of mortality in patients with COVID-19. Therefore, HsTrop-I and CRP levels could help to physicians for earlier triage of the patients that potentially worsening and may lead to provide the effective use of health resources.

Purpose: This study aimed to evaluate the patients who received health services in the pediatric intensive care unit (PICU) of Ankara City Hospital’s Pediatrics Department in a 2-year period and the outcomes of these cases by examining their clinical and demographic characteristics. Materials and Methods: This retrospective study was carried out in the 32-bed tertiary PICU of Ankara City Hospital. The records of 2280 patients between the ages of 1 month and 18 years who were hospitalized in the PICU between September 1, 2019, and September 1, 2021, were retrospectively analyzed. Age, sex, presence of chronic disease, reason for hospitalization in the intensive care unit, length of stay, status and duration of respiratory support, and mortality rates were evaluated. Results: The mean age of the patients was 5.16±5.12 years and the mean PICU stay was 12.47±20.16 days. Bronchiolitis, sepsis, pneumonia, trauma, congenital heart disease, status epilepticus, hematological diseases, oncological diseases, diabetic ketoacidosis, and metabolic diseases were found to be the most common reasons for hospitalization in the PICU. The most frequent underlying diseases were neurological, respiratory, hematological, cardiological, endocrinological, nephrological, gastrointestinal system, oncological, and metabolic diseases. The mortality rate of these patients was 10.8%. Underlying oncological or hematological diseases and immunodeficiency, higher susceptibility to infection, longer hospital stay, and longer duration of mechanical ventilation were found to be statistically significantly higher in deceased patients compared to survivors. Conclusion: The profile of patients admitted to PICUs is expanding day by day. A significant decrease in mortality was observed in all patient groups as a multidisciplinary approach was implemented. It was also observed that most of the patients had an underlying chronic disease and this condition was associated with mortality.

In emergency department, a delayed diagnosis and treatment of ileus causes a substantial increase in morbidity and mortality. : In this study we aimed to determine the major risk factors of mortality and hospital stay length in patients with ileus. It was determined that blood transfusion requirement; lactate, total bilirubin, and C-reactive protein levels; presence of colon cancer; and mean arterial pressure were among the parameters that can be used for predicting mortality in patients with ileus. In addition, qSOFA value and potassium, sodium, and total protein levels were determined to be among the parameters that are effective for determining the need for surgery in patients with ileus.