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Anorexia nervosa is a psychiatric disorder characterized by severe low body weight, impaired self-body image, and intense fear of gaining weight, however its etiopathogenesis is not fully known. Some studies show that nutritional rehabilitation and corresponding weight restoration are not effective enough in the management of intestinal dysbiosis in patients with anorexia nervosa, but results are inconclusive. This work aims to review the existing studies to provide information about the possible role of intestinal microbiota in the pathophysiology of anorexia nervosa, characteristics of intestinal dysbiosis in patients with anorexia nervosa, and possible treatment approaches in the management of intestinal microbiota. [ABSTRACT FROM AUTHOR]

One of the main complications of long-term use of permanent catheters is infection of the catheter. Guidelines issued by the Infectious Diaseases Society of America (IDSA) recommend the additon of antibiotic lock therapy to parenteral antibiotic therapy for tunneled or implantable catheter-associated infections caused by coagulase-negative Staphylococcus, S aureus, and gram-negative rods when removal of the catheter is not an option. However, IDSA guidelines strongly recommend removal of the catheter if possible in patients with catheter-associated infections secondary to Candida. However, Candida-associated catheter infections are common in certain high-risk patient groups including those with short bowel syndrome and congenital diarrheal disorders. Such situationsmay necessitate frequent ghange of catheters along with a host of other complications, resulting in huge loss of revenue to hospitals as well as inconvenience to patients. Here, we present a case in which C. glabrata-associated catheter infection was successfully treated by applying liposomal amphotericin B lock along with systemic antifungal treatment. The patient was a young girl aged 2 years and 9 months having Neurogenin-3 (NEUROG3) gene defect associated with congenital intestinal malabsorption syndrome. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to search the effects of enteral beta glucan to intestinal adaptation at rats which have been performed massive intestinal resection and anastomosis. Methods: Thirty female Wistar rats were included in this study. Rats were divided in to 3 groups (sham, control, and treatment). In control and treatment group 80% small bowell resection was performed. In treatment group, 25 mg/day beta glucan was given by orogastric feeding route. Rats were sacrificed on 14th day. Macroscopic and microscopic changes were recorded. Results: In the treatment group intestinal length, mucosal thickness, villus height and crypt depth were increased statistically significantly. Conclusion: In this study we observed the effects of beta glucan on intestinal length and microscopically changes after massive intestinal resection, as well as the effects of beta glucan on intestinal lymphoproliferation. [ABSTRACT FROM AUTHOR]