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Objectives: We aimed to determine the sensitivity and specificity of fine needle aspiration biopsy (FNAB) in patients with parotid masses., Patients and Methods: The study included 29 patients (15 males, 14 females; mean age 52 years; range 20 to 83 years) who underwent FNAB and parotidectomy for parotid masses. After a detailed history taking, otorhinolaryngologic and systemic examinations were performed. Neck ultrasonography and, when needed, neck computed tomography were used. Superficial parotidectomy was performed in 20 patients and total parotidectomy in nine patients., Results: The results of FNAB were reported as benign in 21 patients (72.4%), malignant in six patients (20.7%), and suspicious in two patients (6.9%). Postoperative histopathologic diagnoses were reported as benign in 17 patients (58.6%) and malignant in 12 patients (41.4%). The sensitivity and specificity rates for FNAB were 54.6% and 100%, respectively. The most common histopathological diagnosis was pleomorphic adenoma (n=7, 24.1%), followed by mucoepidermoid carcinoma (n=4, 13.8%), and Warthin's tumor (n=3, 10.3%)., Conclusion: Preoperative FNAB for parotid masses plays an important role in planning surgery.

The aim of this study was to evaluate the diagnostic accuracy of bronchial biopsy specimens in establishing the specific cell type in primary lung cancer and to study the influence of several factors on this accuracy. 127 patients with lung cancer diagnosed by bronchoscopic biopsy specimens who subsequently underwent thoracotomy between April 2003 and December 2005 were included. There was cell agreement was between bronchoscopic biopsy and thoracotomy in 114 (89.8%) cases. The cell agreement was 92.5% in cases with squamous cell carcinoma and 42.8% in cases with adenocarcinoma (p= 0.002). Stage of the tumor, localization and morphology of the lesion had no effect on cell type agreement (p> 0.05). Cell type agreement in lesions without necrosis was higher (p= 0.09). Cell type agreement was 100% in well differentiated tumors, 94% in moderate differentiated tumors and 66.7% in poor differentiated tumors (p= 0.001). Similar results was demonstrated by the diameter of the tumor (p= 0.008); the smaller the diameter, the greater the cell agreement. In conclusion, cancer-cell type designation from bronchoscopic biopsy specimens is not without erroneous. The degree of cell differentiation is the most important factor affecting cell agreement.