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Objective: Hemolytic uremic syndrome (HUS) is characterised by acute kidney injury, hemolytic anemia and thrombocytopenia. In children, it is mostly related with diarrhea (D+). In this paper, we aimed to determine clinical parameters and prognostic factors in D+HUS. Materials and Methods: This retrospective study was conducted with D+HUS 15 pediatric patients in a pediatric intensive care unit between March 2019 and August 2020. Patients demographics, initial vital signs, laboratory parameters (hemoglobine, hematocrit, white blood cell, platellets, creatinine, urea, uric acid, lactat dehydrogenase, aspartat aminotransferase, alanine aminotransferase, amilase, albumine, C3 and C4), plasma therapy, plasma exchange, RRT type and duration, and the need for blood products were evaluated. Therefore, extra-renal involvement, eculizumab treatment and last follow-up were recorded. Results: The study group consisted of 9 males (60%) and the median age was calculated as 18 months. In 60% of the patients, RRT was implemented. Peritoneal dialysis (in 5) was the most preferded dialysis method. Five patients (33%) had extra-renal involvement. Nine patients (60%) had completely recovered, therefore proteinuria, chronic kidney disease, end-stage kidney disease and neurologic sequel developed in 3 (20%), 1 (6.6%), 1 (6.6%) and 1 (6.6%), respectively. Hospitalization and oligoanuria duration had a significant impact on sequel development [Hospitalization duration: OR:1.28 (%95 CI:0.77-0.98) (p=0.04), Oligoanuria duration: OR:1.46 (%95 CI:0.94-1) (p=0.04)]. Conclusion: In this study, we showed that hospitalization and oligoanuria duration had a significant impact on sequel development. We believe that there is a need for more clinical studies to delinate more precise mechanisms of the disease and eliminate worse outcomes of D+HUS. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Nephrology, Dialysis & Transplantation Journal is the property of Turkish Society of Nephrology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Peritonitis associated with gram-negative bacteria presents difficulties in the follow-up of patients with chronic peritoneal dialysis. Especially in perionitis related to Pseudomonas spp., treatment becomes difficult and may lead to catheter removal. However, some strains may differ. Here, we present a 14-year-old girl with P. putida peritonitis while on automated peritoneal dialysis due to familial Mediterranean fever (FMF)-related amyloidosis and end-stage renal failure. The patient was admitted with abdominal pain, fever, vomiting and cloudy peritoneal fluid starting one day before the admission. She was diagnosed with peritonitis when additional large amounts of leukocytes with 100% polymorphic nucleated cells were found in the peritoneal fluid. Intraperitoneal cefepime treatment was instituted empirically and systemic cefepime was added for up to three days when catheter dysfunction developed. The peritoneal fluid culture yielded cefepime sensitive P. putida and the treatment was stopped at the end of two weeks. No peritonitis recurrence or technical survival problem was found in the follow-up period. It was thought that infection with P. putida, which is thought to be an opportunistic pathogen with low virulence and high response to antibiotic therapy seen in immunosuppressive patients, may be related to canakinumab, which was being used by our case. The case was presented with the aim of drawing attention to the fact that although a pseudomonal peritonitis, two weeks of cefepime monotherapy may be sufficient for P. putida peritonitis. [ABSTRACT FROM AUTHOR]

Ramsay Hunt Syndrome (RHS) was first described by J.Ramsay Hunt in 1907. Ramsay Hunt Syndrome-also known as Herpes Zoster Oticus-consists of facial paralysis accompanied by the presence of erythematous vesicles on ear and/or oral mucosa and otalgia. This syndrome is most common in adults and older children and very rare in young children. Affected children display milder symptoms relative to adults. Following the primary infection, Varicella Zoster Virus (VZV) becomes latent in the cells of the sensory ganglia and a reactivation associated with supressed cell-mediated immunity may occur after a period of time, resulting in RHS. Although subfebrile fever and chickenpox-like rash can develop related to Varicella vaccine, the risk of RHS is extremely rare after immunization. It has been reported that the microorganism introduced into the body by means of live attenuated varicella vaccine becomes activated and causes varicella especially in immunocompromised patients. Following receipt of varicella vaccine, RHS has been also reported to occur rarely. We, herein, report the case of 13-montli-old female patient with infantile nephrotic syndrome who developed RHS after lier immunization with with varicella, and other live vaccines. [ABSTRACT FROM AUTHOR]

Percutaneous nephrostomy is a well-known therapy for urinary drainage in patients with supravesical urinary tract obstruction. This procedure which was firstly applied by Goodwin et al in 1955 is known to be performed in patients with various urologie problems for many years, especially in adults. Percutaneous nephrostomy has generally been performed by urologists or interventional radiologists and it is recognized as a difficult procedure to apply, especially in the neonatal period. As discussed in this neonatal case, PN have a very effective role in the diagnosis and management of neonatal hydronephrosis, even it might be a life-saving procedure which can also be performed by an experienced pediatric ncphrologist. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Dr. Behcet Uz Children's Hospital is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi is the property of Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)