10 results on '"ANHEDONIA"'
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2. DEPRESYON VE KİŞİLİK DEĞİŞİKLİLERİ İLE ORTAYA ÇIKAN GLİOBLASTOMA: BİR OLGU SUNUMU.
- Author
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KAPICI, Yaşar, BAYAR KAPICI, Olga, EGELİ, Aslı, and TEKİN, Atilla
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PERSONALITY change , *SYMPTOMS , *BRAIN tumors , *APPETITE loss , *PROGNOSIS , *CEREBELLAR tumors - Abstract
Glioblastoma is the most common poor prognosis brain tumor in adults. Although neurological signs are often seen as first symptoms at clinical course of GBM, pychiatric symptoms also accompany the presentation. Mood and personality changes, anxiety and psychosis are the most common psychiatric symptoms in presentation of GBM. In this article, a 57-year-old man admitted to emergency unit with social isolation, anhedonia, loss of appetite, sleep disturbances and personality changes is reported. In this case, a 7x4 cm-sized lesion with a mass effect from the left frontoparietal region and extending to the temporal lobe was found. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
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3. Reliability and Validity of the Snaith-Hamilton Pleasure Scale Clinician Administered Turkish Form.
- Author
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Gürcan A, Başar K, Şen ZD, and Karakaşli AA
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- Humans, Language, Pleasure, Reproducibility of Results, Anhedonia, Depressive Disorder, Major diagnosis
- Abstract
Objective: Anhedonia, which is defined as diminished capacity of having pleasure, is a common symptom in many mental disorders. It has been aimed in this study to adapt to the Turkish language the Snaith- Hamilton Pleasure Scale Clinician Administered Form (SHAPS-C) and examining reliability and validity of Snaith-Hamilton Pleasure Scale Clinician Administered Turkish Form (SHAPS-C-TR) which measures anhedonia in clinical and healthy samples., Method: Two groups consisting of 63 participants consulting the psychiatry clinic and 67 non-clinical participants were included in the study. Data were collected with the Turkish version of the SHAPS-C (the SHAPS-C-TR), the Beck Depression Inventory (BDI), the Montgomery-Asberg Depression Rating Scale (MADRS) and the Positive Negative Affect Scale (PANAS)., Results: The Kuder-Richardson internal consistency coefficient for the entire participants, the clinical and the non-clinical group were, 0.765, 0.813 and 0.657 respectively. The intra-class coefficient for test-retest reliability was 0.732. The total score on the SHAPS-C-TR significantly correlated with the scores on the anhedonia items of the BDI and the MADRS but not the scores on anxiety items. The PANAS positive symptoms scores were negatively correlated with the SHAPSC- TR total score. In the clinical group, the participants followed up with depression had significantly higher SHAPS-C-TR score than the rest of the participants. A similar difference was not demonstrated by the scores of the clinical group participants followed up with anxiety disorder. Scores on the SHAPS-C-TR did not vary with respect to the demographic characteristics of the participants., Conclusion: The SHAPS-C-TR is a valid and reliable measurement tool to assess anhedonia in both clinical and non-clinical individuals irrespective of differences in demographic features.
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- 2022
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- View/download PDF
4. Depresif Duygudurumdan Major Depresyona Klinik Spektrum.
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Aslan, Aslı Akın, Sarı, Burcu Akın, and Kuruoğlu, Aslı
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MENTAL depression , *SYMPTOMS , *MEDICAL care , *SADNESS , *BEREAVEMENT , *ANHEDONIA - Abstract
In recent days some depressive moods as sadness, mourning and enervation that aren't defined in DSM-IV, have been sensed by plenty of people. Some of these feelings have mentioned in literature. With these fact subthreshold depressive symptoms that do not meet the DSM IV diagnostic criteria for major depressive disorder and classified as Depressive Disorder Not Otherwise Specified (DD-NOS) was associated with significant functional impairments and risk for future major depressive episode. After all there is still no standard treatment for subthreshold depression. In the absence of dysphoria or anhedonia, the patient with other depressive symptoms does not fit any category of depressive disorders. However, limited studies show the reduction of functioning in these patients highlight the importance of diagnosis and treatment of depressive spectrum disorders. Subthreshold depression may seen in many cases of psychiatric or medical disorders which also can be associated with life events and increasing risk of developing major depression. Although there are some studies about diagnosis and treatment of subthreshold depressive symptoms in specific sample groups such as elderly population or the people with other medical illness; the results are not suitable for general population. Further well-designed studies are needed to determine suitable scales for diagnosis of subthreshold depressive symptoms as well as when and how to interfere these symptoms to standardize the treatment. This review aims to define and focus on clinical significance of subthreshold depressions. [ABSTRACT FROM AUTHOR]
- Published
- 2012
5. İntiharı Öngörebilecek Bir Araç: Hastane Anksiyete ve Depresyon Ölçeği.
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Karamustafalıoğlu, Oğuz, özcelik, Başak, Bakım, Bahadır, Ceylan, Yasemin Cengiz, Yavuz, Burcu Göksan, GÜven, Tuğba, and Gönenli, Sinem
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SUICIDAL behavior , *PSYCHIATRIC hospital patients , *INPATIENT care , *PSYCHIATRIC hospitals , *INTERVIEWING in psychiatry , *PSYCHOTHERAPY patients , *MEDICAL history taking - Abstract
Objective: The aim of this study was to compare the anxiety and depressive symptoms between the suicide attempters and non-suicide attempters and to determine the differences in the Hospital Anxiety and Depression Scale (HADS) items inpatient between the two groups. Method: The study participants were age-matched 50 suicide attempters who were admitted to Sisli Etfal Research and Training Hospital, and 50 inpatients who were hospitalized due to their general medical complaints. The sociodemographic form, the HADS and the Mini-International Neuropsychiatric Interview (MINI) were administered. Results: The suicide attempters had significantly higher rate of previous psychiatric history p=0.017, psychiatric hospitalization p=0.041, family history p=0.023, and alcohol/substance use p=0.004. The suicide attempters scored significantly higher on tension, anhedonia, fear, loss of humor, restlessness, and lack of enjoyment. Conclusions: Clinicians should take into account the presence of previous psychiatric history, family history, substance/alcohol use, presence of anhedonia, lack of enjoyment, loss of humor, fear, tension and restlessness. The HADS could be a powerful tool to assess the suicide risk other than psychiatric evaluation. [ABSTRACT FROM AUTHOR]
- Published
- 2010
6. Gözden Geçirilmiş Fiziksel Anhedoni Ölçeğinin Türkçe Formunun Üniversite Öğrencilerinde Geçerlilik ve Güvenilirliği.
- Author
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BASKAK, Bora, CAN SAKA, Meram, GÖNÜLLÜ, İpek, ARTAR, Müge, ÖZEL KIZIL, Erguvan Tuğba, YAZICI, M. Kazım, CUHADAROĞU, Füsun, PALAOĞU, Özden, and ATBAŞOĞU, E. Cem
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STATISTICAL reliability , *ANHEDONIA , *SCHIZOPHRENIA , *SCHIZOTYPAL personality disorder , *SOCIOCULTURAL factors , *COLLEGE students' psychology research - Abstract
Objective: Rado and Meehl proposed anhedonia as a main symptom and as a basis of other symptoms of schizotypy and schizophrenia. However, anhedonia was accepted as an important and standard symptom of schizophrenia after being classified as negative symptom by Andreassen. Chapman examined anhedonia as social and physical, and in 1976, has developed the Physical Anhedonia Scale (PAS); it has been frequently used in the research projects. This study aims to explore the validity and reliability of the PAS-Turkish version in university students. Methods: PAS was translated into Turkish and some items were culturally adapted. The Turkish version was applied to university students twice with a three-week interval. Results: Regarding the internal consistency of the scale, the α values were: 0.84 for the whole sample, 0,85 for males and 0.82 for females. Eleven items with low item-rest correlations were excluded from the Turkish version. The test-retest reliability was 0,60. Discussion: The internal consistency and test-retest reliability values were acceptable. The Turkish version of PAS is eligible to be used in schizotypy research and to test different hypothesis related to physical anhedonia. However, it must be noted that the concept of physical anhedonia is considerably influenced by culture. [ABSTRACT FROM AUTHOR]
- Published
- 2009
7. Nikotin tercih eden sıçan soylarında nikotin yoksunluğunun sukroz tercihine etkisi
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Zinde, Aylin, Keser, Ayşegül, Fizyoloji Anabilim Dalı, and Sağlık Bilimleri Enstitüsü
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Fizyoloji ,Nicotine ,Nicotine Preferring Rat Lines ,Nikotin Tercih Eden Sıçan Soyu ,Anhedonia ,Physiology ,Anhedoni ,Nikotin ,Sukroz Tercihi ,Sucrose Preference - Abstract
Bağımlılığın ortaya çıkışında, yoksunluk ile tetiklenen stres yanıtı ve negatif afekt önemli rol oynamaktadır. Pek çok yayında nikotin bağımlılığının gelişiminde çevresel faktörlerin yanı sıra genetik faktörlerin de önemi vurgulanmaktadır. İnsanda sigaraya başlama, sigara içimin sürdürülmesi, yoksunluk bulguları ve sigaranın bırakılmasındaki başarı düzeyi gibi nikotin bağımlılığı ile ilişkili özelliklerin herediter geçiş gösterebildiği bildirilmektedir. Ege Üniversitesi, Laboratuvar Hayvanları Uygulama ve Araştırma Merkezinde seçici tohumlama yöntemi kullanarak, nikotini suya tercih eden ve bu davranışı bir sonraki jenerasyona aktarabilen özel bir sıçan soyu üretilmişti. Gerçekleştirdiğimiz bu tez çalışmasında, nikotini tercih eden (NT) sıçan soyunda nikotin yoksunluğunun duygu-durum üzerine etkilerinin ortaya koyulması amaçlanmaktadır. Araştırma 4 deney grubu ile (n = 12) yapılmıştır: Kontrol Erkek (KE), Kontrol Dişi (KD), NT soy Erkek (NTE), NT soy Dişi (NTD). Tüm deney gruplarına yedi gün oral sukroz tercihi testi (STT) uygulandıktan sonra sekiz hafta zorlu oral nikotin (50 μg/ml) verilmiştir. Ardından on günlük nikotin yoksunluğu sırasında STT tekrarlanmıştır. Grupların sukroz tüketim miktarları arasındaki farkların istatistiksel analizi için SPSS programı kullanılmıştır. Bazal ve yoksunluk sukroz tüketimi verilerinin karşılaştırmasında nikotin, yoksunluğu (p = 0,042), gün (p < 0,001), soy (p < 0,001) ve cinsiyet (p < 0,001) açısından farklar bulunmuştur. Soy ile cinsiyet (p < 0,001), soy ile nikotin yoksunluğu (p = 0,039) etkileşimleri saptanmıştır. Bazal ve yoksunluk durumunda KD’ler diğer gruplardan daha fazla sukroz tüketmiştir. Yoksunlukta sukroz tüketiminin tüm gruplarda azalması anhedoninin geliştiğini göstermiştir. Bazal ve yoksunluk durumunda kontrol grupları arasında belirgin cinsiyet farkı bulunmuştur. NT grupta bazal durumda cinsiyet farkı yokken yoksunlukta cinsiyet farkı gelişmiştir. Bazal durumla karşılaştırıldığında, yoksunlukta hedoni seviyesinde en belirgin düşüş KD’lerde gözlenmiştir. KD’ler yoksunluğun birinci gününden itibaren anhedonik iken KE’lerde yoksunluğun birinci gününde anhedoni gözlenmemiştir. NTD’ler hem bazal şartlarda hem de yoksunlukta KD’lerden daha az sukroz tüketmişlerdir. Bu durum NTD’lerin KD’lerden daha çok anhedoni yaşadıklarına işaret etmektedir Erkek gruplarında hem bazal hem de yoksunluk durumunda benzer düzeyde anhedoni saptanmıştır. NT sıçanlarda kontrollere oranla cinsiyet farkı azalmış, dişiler erkeklere benzer davranış sergilemiştir. Yoksunluğun birinci günü 1., 2., 4., 6. ve 24. saatlerde alınan sukroz tüketimi verileri değerlendirilmesinde soy (p = 0,031) ve cinsiyetin (p < 0,001) anlamlı farklılığa yol açtığı ayrıca saatler ile soy, saatler ile cinsiyet ve saatler, soy ile cinsiyet arasında p < 0,001 düzeyinde etkileşim olduğu saptanmıştır. Sukroz tercihleri verileri değerlendirilmesinde ise saatler (p < 0,001) açısından anlamlı fark bulunmuştur ayrıca saatler ile soy arasında etkileşim olduğu saptanmıştır. Yoksunlukta, KD grubu KE grubuna oranla daha erken anhedoni geliştirmiş ve hedonik seviyeleri daha şiddetli düşüş göstermiştir. Bu sonuç, sigara tiryakisi kadınların erkeklere oranla nikotine daha bağımlı olduğunu ve sigarayı bırakmakta daha çok zorlandığını gösteren diğer çalışma sonuçları ile uyumlu bulunmuştur. NTD grubu, KD grubuna göre nikotin yoksunluğu sırasında daha fazla anhedoni göstermiştir. Ancak NT grupları arasında anlamlı cinsiyet farkı bulunmamıştır. NT sıçan soyunda yoksunlukta gözlenen bu negatif duygu-durum nikotin bağımlılığının gelişimine önemli bir katkı veriyor olabilir., Stress response and negative affect induced by withdrawal plays important roles in the development of drug addiction. In our laboratory, a nicotine-preferring (NP) rat line has been generated using selective breeding method. In this study, we aimed to reveal the regulatory effect of inherited genetic background on nicotine withdrawal-induced negative affect. Therefore, we studied the differences in basal and withdrawal induced-anhedonia between NP rat lines and their controls. This study involved 4 groups (n = 12): Control Males (CM), Females (CF), NP Males (NPM), and Females (NPF). In all groups, sucrose preference test was performed for seven days, followed by forced oral nicotine (50 μg/ml) administration for eight weeks. Sucrose preference was repeated during withdrawal which lasted ten days. Data were analyzed using SPSS statistics software. When basal and withdrawal data were compared for sucrose consumption, there were effects of withdrawal (p = 0.042), days (p < 0.001), line (p < 0.001) and sex (p < 0.001). Also, there were line and sex (p < 0.001) and line and withdrawal (p = 0.039) interactions. CF, compared to other groups, consumed more sucrose during basal and withdrawal conditions. In withdrawal, attenuated sucrose consumption in all groups indicated anhedonia. There was significant sex difference in basal and withdrawal sucrose consumption between control groups. In NP groups, there was no sex difference in basal sucrose consumption while a sex difference has shown during withdrawal. Compared to basal status, the most significant decrease in hedonic level was observed in CFs. While CFs were anhedonic from the first day of withdrawal, anhedonia was not observed on the first day of withdrawal in CMs. NPFs consumed less sucrose than CF in both basal conditions and withdrawal. This indicates that NPFs experience more anhedonia than CFs. The sex difference in NP rats was decreased compared to controls and females showed similar behavior to males. There was a main effect of line (p = 0,031) and sex (p < 0,001) on hourly sucrose consumption data at 1st, 2nd, 4th, 6th and 24th hours on the first day of withdrawal. Additionally, there were line and sex, hours and line, hours and sex, hours, line and sex interactions. Also there was a main effect of hours (p < 0,001) on sucrose preference data and hours and line interaction. During withdrawal, CFs showed earlier anhedonia than CMs. CFs showed more severe hedonic attenuation than CMs. This result is similar with the studies that indicate women are more addict to nicotine than men. In sucrose consumption data NPFs showed more anhedonia than CFs during withdrawal. But there were no significant sex difference in NP rats. The negative affect shown in NP rat lines during withdrawal may contribute to the development of nicotine addiction.
- Published
- 2020
8. Letter to the Editor: Depression As The First Symptom Of Frontal Lobe Grade 2 Malignant Glioma.
- Author
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Nazlı ŞB and Sevindik M
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- Adult, Aged, Anhedonia, Child, Depression, Female, Frontal Lobe, Humans, Quality of Life, Brain Neoplasms complications, Depressive Disorder, Major, Glioma complications, Glioma diagnosis, Glioma pathology
- Abstract
Dear Editor, Next to focal neurological symptoms, epileptic seizures and head aches, brain tumors can less frequently bring about cognitive changes, slowed speech, difficulty sustaining mental functioning and psychiatric symptoms of personality changes and. loss of interest in daily activities, these symptoms may be evaluated as anxiety or depression. Depression is known to be a complication of brain tumours and may sometimes be seen after the presentation of neurological symptoms linked to brain tumours, and sometimes after tumor treatment (Oğuz et al. 2005, Litofsky et al. 2004, Moise and Madhusoodanan 2006, Oreskovic M et al. 2007, Rooney A et al. 2010). The dorsolateral prefrontal, orbitofrontal and medial frontal circuits constitute the three subcortical neuronal circuits in the frontal cortex. The dorsolateral prefrontal circuit is associated with planning and operational functions and lesions on it may give rise to apathy, abulia, perseveration, personality changes and planning disorder. Lesions involving the orbitofrontal circuit, which is associated with response suppression and disinhibition, may involve emotional lability and memory problems. Whereas lesions affecting the right orbitofrontal circuit give rise to elevated mood, lesions on the left orbitofrontal circuit lead to depressed mood. In cases with medial frontal circuit involvement, akinetic mutism may result from lesions in the superior medial region and anteroretrograde amnesia and confabulation are observed with lesions in the inferior medial region (Tosun et al. 2016, Chirchiglia 2018). A diagnosis of psychiatric disorder may be given during the first examination of patieants with primary brain tumours, especially if localized in the frontal lobe. Thorough history taking and physical examination are necessary for early diagnosis. The case reported here concerns a 29-year-old university graduate female patient, living with her partner and children, who consulted the clinic with complaints of tendency to frequent crying, anhedonia, having difficulty with speech fluency, forgetfulness and distractedness that had presented suddenly, 2 months previously, without any causative stressor. In her mental status examination, she appeared having normal self-care with appearance at her actual age. She was fully conscious and oriented, not willing to cooperate with the interview, had distinct difficulty in maintaining attention and with fluency of speech. Her mood was depressive. She described loss of appetite, fatigue and energy loss. Her difficulty in paying attention was pronounced. She did not have a history of psychotropic medication use or family history of psychiatric disease. She did not smoke or use alcohol or substance. After evaluating the clinical interview, a preliminary diagnosis of major depressive disorder was considered on the basis of the DSM-5 criteria. Routine blood tests were requested. Given the continuation of her complaints, the difficulty with fluent speech and the increase in tendency to sleep at the first week follow up, cranial MRI was planned. The MRI results showed on the right, in the frontal lobe a multilocular mass with precallosal extension, undiscernable margins with the right lateral aspect of the corpus callosum genu and dispersed cystic-necrotic areas with T2 signal series. The dimensions of the mass were nearly 5 x 3 cm causing a 1-cm right-to-left shift of the midline (Figure 1) DEPRESSION AS THE FIRST SYMPTOM OF FRONTAL LOBE GRADE 2 MALIGNANT GLIOMA 2 Türk Psikiyatri Dergisi 2 Turkish Journal of Psychiatry Letter to the Editor 143 144 The patient was referred for surgery with the preliminary diagnosis of high-grade glial tumour. Pathology results identified a grade 2 glioma. It was learned that radiotherapy sessions were begun after surgery. The patient did not have any symptoms of psychopathology during the 2 monthly psychiatric interviews made after surgery. Brain tumours generally indicate their presence with headache, seizures and other neurological symptoms and very rarely with depression as seen in the case of our patient. It should be kept in mind that atypical psychiatric symptoms may have an underlying organic lesion and subtle neurological symptoms should be investigated in detail. A recent meta-analysis on 37 observational studies determined a 21.7% prevalence of depression in a total of 4518 patients with intracranial tumours. Comorbidity of depression with brain tumor was demonstrated to worsen the quality of life, increase suicidal risk and lower the chance of survival (Huang et al. 2017). The possibility of psychiatric symptoms being the clinical clues for brain cancer was noted and the necessity of neuroimaging tests in cases of recent-onset psychosis or mood disorder symptoms, atypical personality changes and anorexia without body dysmorphic disorder was emphasized (Madhusoodanan et al. 2015). Loss of interest, tendency to frequent weeping, introversion and anhedonia were the sole complaints in the case discussed here. The increase in psychomotor retardation and slowing down of movements at the very first weekly control follow up necessitated neuroimaging. Despite the reports in the literature on the frequent association of unpreventable excessive behavior, disinhibition and irritability with right frontal injury and lesions (Okumuş and Hocaoğlu 2018), depression was the dominant symptom in the case presented here. There are differences between primary major depression and depression presenting with underlying somatic diseases which is known to occur at later ages (Rouchell et al. 2002). However, our patient was aged 29 years. Also, cases of depression due to somatic disease are less associated with family history of depression and suicidal ideation and attempts, while cognitive symptoms come to the foreground during mental status examination. (Sertöz and Mete 2004, Rouchell et al. 2002). Our patient did not have suicidal ideation or attempts, or a family history of depression. In apathy, which may be explained as emotional blunting, indifference or detachment from the external world, targeted behavior is also reduced next to the lack of emotional expression. The individual discussed here was learned not to sit at the table or change the television channel unless reminded to do so. When the reason was asked, she could not think of one. The reduction in emotional expression accompanies reduced insight, abulia and lack of empathy (Sözeri Varma et al. 2019). In depression, apathy is defined as 'sorrowless depression'. Our patient cried but had very blunted mimics and gestures. She explained that she could not help weeping even at times when she did not feel internally distressed. The seriousness of apathy, as a symptom difficult to differentiate from depression, is still not understood. Neuroimaging Figure 1- Cranial MRI of the patient 145 Received: 16.08.2020, Accepted: 04.12.2020, Available Online Date: 05.10.2021 1MD., Antalya Kepez State Hospital, Department of Psychiatry, Antalya, 2MD., Ordu University Training and Research Hospital, Department of Psychiatry, Ordu, Turkey e-mail: bosbora@yahoo.com https://doi.org/10.5080/u25957 studies indicate apathy to be a reflect of impaired frontal-subcortical circuits and the functional disorder of the connections between the ventromedial prefrontal cortex and the basal ganglia (Chase 2011). Comparison of 45 individuals with depression due to aging and 43 healthy individuals showed apathy to be associated with fronto-limbic gray and white matter abnormalities which continued after antidepressant treatment. The structural anomalies of the posterior subgenual cingulate gyrus and the uncinate fasciculus were discussed (Yuen 2014). The case discussed here is presented to emphasize the importance of brain imaging methods and detailed investigation of atypical symptoms for diagnostic approaches to psychiatric disorders. Especially, complaints at young age of depression with psychomotor retardation, reduced fluency of speech and sudden onset withdrawal without stressors should be a warning of secondary depression. Yours sincerely... Şerif Bora Nazlı1 , Muhammet Sevindik2 REFERENCES Chase TN (2011) Apathy in Neuropsychiatric Disease: Diagnosis, Pathophysiology, and Treatment. Neurotox Res 19:266-78. Chirchiglia D (2018) Pseudodepression as an Anticipatory Symptom of Frontal Lobe Brain Tumors. Int J Depress Anxiety 1:007. Huang J, Zeng C, Xiao J et al (2017) Association between depression and brain tumor: a systematic review and meta-analysis. Oncotarget 8:94932-43. Litofsky NS, Farace E, Anderson F et al (2004) Depression in patients with high-grade glioma: Results of the glioma outcomes project. Neurosurgery 54:358-67. Madhusoodanan S, Ting MB, Farah T et al (2015) Pyschiatric aspects of brain tumors: A review. World J Psychiatry 5:273-85. Moise D, Madhusoodanan S (2006) Psychiatric symptoms associated with brain tumors: a clinical enigma. CNS Spectr 2006;11:28-31. Oğuz N, Ilnem C, Yener F (2005) Psychiatric symptoms in brain tumors: Case reports. Bulletin of Clinical Psychopharmacology 15:18-21. Hocaoğlu Ç, Okumuş B (2018) Psychiatric manifestations and brain tumor: A case report and brief review. The Medical Journal of Mustafa Kemal University 9:42-9. Oreskovic NM, Strother CG, Zibners LM (2007) An unusual case of a central nervous system tumor presenting as a chief complaint of depression. Pediatric Emergency Care 23:486-8. Rooney A, Carson A, Grant R (2011) Depression in cerebral glioma patients: a systematic review of observational studies. J Natl Cancer Inst103:61-76. Rouchell AM, Pounds R, Tierney JG (2002) Depression Textbook of Consultation-Liaison Psychiatry, 2nd Edition, Volume 1. MG Wise, JR Rundell (Ed), Washington DC American Psychiatric Publishing, Inc, p.307-38. Özen SÖ, Hayriye ME (2004) Bedensel Hastalıklarda Depresyon. Klinik Psikiyatri Ek 2:63-9. Sözeri Varma G , Bingöl C , Topak O et al (2019) Relationship of apathy with depressive symptom severity and cognitive functions in geriatric depression. Arch Neuropsychiatry 56:133-8. Yuen GS, Gunning FM, Woods E et al (2014) Neuroanatomical correlates of apathy in late-life depression and antidepressant treatment response. J Affect Disord 166:179-86.
- Published
- 2022
- Full Text
- View/download PDF
9. Üniversite öğrencilerinin sosyal medya kullanım sıklıkları ile anksiyete, anhedoni ve dürtüsellik düzeyleri arasındaki ilişki
- Author
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Dedekli, Eren, Kesebir, Sermin, and Klinik Psikoloji Anabilim Dalı
- Subjects
Social media ,Psikoloji ,Anhedonia ,Psychology ,Impulsive behavior ,Anxiety ,University students - Abstract
Bu çalışanın amacı üniversite öğrencilerinin sosyal medya kullanım sıklıkları ile anksiyete, anhedoni ve dürtüsellik düzeyleri arasındaki ilişkinin incelenmesidir. Araştırmamızın örneklemini, gönüllük esasıyla belirlenen 60'ı kadın ve 45'i erkek olan, T.C. ÜSKÜDAR ÜNİVERSİTESİ lisans düzeyi öğrenciler oluşturmuş, veri toplamak amacıyla, demografik bilgi formu, Beck Anksiyete, Barratt Dürtüsellik ve Snaith Hamilton Değerlendirme ölçekleri uygulanmış, verileri analizinde ise, SPSS alt testlerinden yararlanılmıştır. Sayısal değişkenlerin karşılaştırılması T, sınıfsal değişkenlerin karşılaştırılması ki-kare ve bağlantı analizleri ise, pearson korelasyon testleriyle gerçekleştirilmiştir.Öğrencilerin, %68,6'sının her gün 0-4 saat arası internette zaman geçirdiği, %91,4'nün bu zamanın 0-3 saatini sosyal medya platformlarının kullanımına ayırdığı, %65,7'sinin interneti kullanım amacının sosyal medya platformlarını takip etmek olduğu, %63,8'nin her gün bir kereden fazla sosyal medya platformlarına giriş yaptığı ve %33,3'nün sosyal medya platformlarını, gündemi takip etmek adına kullandıkları tespit edilmiş olmakla birlikte, Katılımcılar tarafından en sık kullandıkları sosyal medya platformunun %37,1 ile Facebook olduğu sonucuna ulaşılmıştır.Araştırmamız neticesinde, öğrencilerin sosyal medya kullanım sıklıkları ile anksiyete düzeyleri arasında anlamlı bir ilişkinin olmadığı (p>0,05), sosyal medya kullanım sıklıkları ile anhedoni düzeyleri arasında anlamlı bir ilişkinin olmadığı (p>0,05) sonucuna ulaşılmasının yanında, katılımcıların sosyal medya kullanım sıklıkları ile dürtüsellik düzeyleri arasında anlamlı bir ilişkiye ulaşılmış olup, bireylerin sosyal medya kullanım sıklıkları arttıkça dürtüsellik düzeylerinin de arttığı tespit edilmiştir (r=0,252, p0,05), anksiyete ile dürtüsellik (p>0,05) ve anhedoni ile dürtüsellik (p>0,05) arasında anlamlı bir ilişkiye ulaşılamamıştır. Anahtar Kelimeler: Sosyal Medya, Anksiyete, Anhedoni ve Dürtüsellik. The aim of this study is to examine the relationship between the frequency of social media usage among university students and anxiety, anhedonia and impulsivity levels.Undergraduate students, of whom 60% were female and 45% were male, at T.C. USKUDAR UNIVERSITY, who were determined on voluntarily bases, constituted the sample of the study, and demographic information form, Beck Anxiety, Barratt Impulsivity and Snaith Hamilton Evaluation scales were applied for data collection and SPSS sub-tests were used for data analysis. Comparison of numerical variables was performed by T, comparison of class variables was performed by chi-square and link analysis was performed by Pearson correlation tests.It was found that 68.6% of the students spent 0-4 hours on the internet every day, 91.4% spent 0-3 hours on social media platforms, 65.7% used the internet to follow social media platforms, 63.8% visited social media platforms more than once a day, and 33.3% of them used social media platforms to keep up with the agenda, and that Facebook was the most frequently used social media platform with 37.1% of the participants.As a result of our research, it was found that there was no significant relationship between social media usage frequency of students and anxiety levels (p> 0.05), no significant relationship between social media usage frequency and anhedonia levels (p>0.05) , a significant relationship was found between social media usage frequency of participants and impulsivity levels, and it was found that as the frequency of social media usage increased, impulsivity levels also increased (r = 0.252, p 0.05), anxiety and impulsivity (p> 0.05) and anhedonia and impulsivity (p> 0.05).Key Words: Social Media, Anxiety, Anhedonia, İmpulsivity. 124
- Published
- 2018
10. Majör depresyonda ödülle ilişkili öğrenmenin değerlendirilmesi
- Author
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Gürcan, Ahmet, Başar, Koray, and Ruh Sağlığı ve Hastalıkları Anabilim Dalı
- Subjects
Psychiatry ,Anhedonia ,Depression ,Depressive disorder ,Learning ,Depressive disorder-major ,Rewarding ,Psikiyatri - Abstract
Gürcan A., Majör Depresyonda Ödülle İlişkili Öğrenmenin Değerlendirilmesi. Hacettepe Üniversitesi Tıp Fakültesi, Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Uzmanlık Tezi, Ankara, 2017.Amaç: Anhedoni, depresyonun çekirdek belirtilerinden biridir. Son yıllarda ödül süreçleri bağlamında farklı boyutları araştırılan anhedoni majör depresyonun seyrinde ve tedavi yanıtında etkilidir. Bu çalışmada majör depresyonda anhedoninin farklı boyutlarının ölçekler ve ödülle ilişkili öğrenmeyi değerlendiren bir davranışsal görev ile incelenmesi, depresyonun diğer özellikleri ile ilişkisinin değerlendirilmesi amaçlanmıştır. Yöntem: Hacettepe Üniversitesi Erişkin Hastanesi Psikiyatri Polikliniğinde majör depresyon tanısıyla izlenen, yapılandırılmış görüşmeyle (SCID-I) DSM-IV ölçütlerine göre yaşam boyu tanıları doğrulanan 78 hasta araştırmaya alınmıştır. Majör depresyon tanısını karşılamayan hastalar 'Remisyonda Majör Depresyon' (RMD, n=40), majör depresyon tanısını değerlendirme sırasında karşılayan hastalar 'Majör Depresyon' (MD, n=38) gruplarını oluşturmuştur. Halen ve yaşam boyu ruhsal bozukluk tanısı konulmayan 40 bireyle 'Kontrol' (K) grubu oluşturulmuştur. Depresyon şiddeti Beck Depresyon Envanteri'yle (BDE), süreklilik gösteren fiziksel ve sosyal anhedoni Chapman Fiziksel Anhedoni Ölçeği (FAÖ) ve Chapman Sosyal Anhedoni Ölçeği (SAÖ) ile, durumluk anhedoni Klinisyen Tarafından Uygulanan Snaith Hamilton Zevk Alma Ölçeği Türkçe Formu (SHAPS-C-TR) ile, durumluk anksiyete Durumluk-Sürekli Kaygı Envanteri Durumluk Kaygı alt ölçeği (DKE) ile, silik bipolar belirtiler Hipomani Soru Listesi-32-Yenilenmiş Sürümü (HSL) ile, dikkat eksikliği hiperaktivite bozukluğu belirtileri Wender-Utah Derecelendirme Ölçeği (WUDÖ) ile değerlendirilmiştir. Ödülle ilişkili öğrenme Olasılıklandırılmış Ödül Görevi (OÖG) ile değerlendirilmiştir. OÖG ile ilgili değerlendirmeler yapılırken, katılımcıların ÖOG verilerinin analize uygunluğu, depresyon şiddetleri ve dikkat eksikliği hiperaktivite bozukluğuna dair veriler göz önünde bulundurulmuştur. İstatistiksel analizler SPSS Statistics 22.0 kullanılarak, T testi, Mann Whitney U testi, Welch ANOVA, Kruskal Wallis testi, Pearson testi, Spearman testi, ANOVA, ANCOVA ile yapılmıştır. Anlamlılık ölçütü olarak p < 0,05 kabul edilmiştir.Bulgular: Klinisyen tarafından uygulanan SHAPS-C-TR anhedoni puanları MD grubunda, remisyonda depresyon ve kontrol gruplarından yüksek bulunmuştur. Durumsal anhedoniyi değerlendiren bu ölçek puanları FAÖ, SAÖ, BDE anhedoni ve melankoli alt ölçekleri ile ilişki göstermemiştir. Ancak BDE'nin zevk almakta kaybı değerlendiren tek maddesiyle anlamlı ilişki saptanmıştır. Klinisyen tarafından uygulanan SHAPS-C-TR'nin durumsal olarak zevk alma (hedonik kapasite) ile ilişkili anhedoniyi değerlendirdiği düşünülmüştür. Anhedoninin istekle ilgili boyutunu değerlendirmek üzere uygulanan sorular geçerli bulunmamıştır. Anhedoninin ödülle ilişkili öğrenmeyle ilgili boyutunu değerlendirmek üzere uygulanan OÖG verilerinin analizi için, görevin teknik ölçütleri, BDE ve WUDÖ puanları dikkate alınarak bazı katılımcılar dışarıda bırakılmıştır. Yanıt yanlılığı ile ilgili değişkenlerin klinik ölçeklerle değerlendirilen anhedoni puanları ile orta ve üzeri düzeyde ilişkisi gösterilememiştir. Değerlendirilen örneklemin (MD n=15, RMD n=35, K n=37) tümünde ödülle ilgili yanıt yanlılığı (YY) değişiminde blok etkisi gözlenirken, gruplar arasında fark saptanmamıştır. Tüm örneklem SHAPS-C-TR'ye göre (eşik puan: 4) anhedonisi olan (n=12) ve olmayan (n=75) olarak ikiye bölündüğünde YY değişimi açısından gruplar arasında anlamlı fark saptanmamıştır; ancak anhedonisi olmayan grupta ilk blokta YY, hem ikinci, hem de üçüncü bloktakinden anlamlı olarak daha düşük bulunmuştur. Anhedonisi olan grupta ise ardışık bloklar arasında YY değişimi saptanmamıştır. Sonuç: Majör depresyonda zevk almayla ilgili anhedoninin durumsal özellik gösterdiği, ödülle ilişkili öğrenmenin sağlıklı kontrollerden farklı olmadığı gösterilmiştir. Bu bulgunun daha büyük örneklemlerde yinelenmesi gerekmektedir. Ödülle ilişkili öğrenmeyle ilgili bozulmanın depresyon tanısı veya öyküsünden çok ölçeklerle değerlendirilen anhedoninin şiddetiyle ilişkili olabileceği gösterilmiştir. Anahtar Kelimeler: Majör depresyon, anhedoni, ödülle ilişkili öğrenme Bu çalışma 21. Türkiye Psikiyatri Derneği Yıllık Toplantısı ve Klinik Eğitim Sempozyumu'nda (19-22 Nisan 2017, Antalya) verilen Araştırma Projesi Teşvik Ödülü kapsamında Türkiye Psikiyatri Derneği tarafından desteklenmiştir. Gürcan A., Relation of Major Depression with Reward Related Learning. Hacettepe University, Faculty of Medicine, Department of Psychiatry, Dissertation Thesis, Ankara, 2017.Objectives: Anhedonia is the one of the core symptoms of depression. The anhedonia has influences in the progress and response to treatment of major depression and it's investigated in different dimensions in the context of reward processes in recent years. In this study it was aimed to investigate different dimensions of anhedonia by using scales and a behavioral task with assess reward related learning and relation of these dimensions and other features of depression. Method: Seventy eight outpatients diagnosed with major depression and whose lifelong diagnosis was confirmed by Structured Clinical Interview for DSM-IV (SCID-I) and followed by Hacettepe University Hospital Psychiatry Polyclinic were recruited. Patients who didn't have symptoms which fulfill the criteria of major depression constituted 'Remitted Major Depression' group (RMD, n=40), and patients who had still symptoms which fulfill the criteria of major depression constituted the 'Major Depression' group (MD, n=38). Control Group (C) consisted of healthy individuals who were never diagnosed with any psychiatric disorder. Thirty eight patients who had still symptoms which fulfill the criteria of major depression constituted the Major Depression (MD) group and other forty patients constituted the Remitted Major Depression (RMD) group. Comorbid Axis I mental diagnosis other than remitted anxiety disorders were excluded. Depression severity was evaluated with Beck Depression Inventory (BDI), trait like physical anhedonia was evaluated with Chapman Physical Anhedonia Scale (PAS), trait like social anhedonia was evaluated with Chapman Social Anhedonia Scale (SAS), state like anhedonia was evaluated with Clinician Administrated Snaith Hamilton Pleasure Scale Turkish Version (SHAPS-C-TR), state anxiety was evaluated with State-Trait Anxiety Inventory (STAI) state anxiety subscale, subthreshold bipolarity was evaluated with Hypomania Checklist-32-Revised Version (HCL-32-R) and symptoms of attention deficit hyperactivity disorder were evaluated with Wender Utah Rating Scale(WURS). Reward related learning was evaluated with Probabilistic Reward Task (PRT) which is a behavioral task. While analyzing the data of PRT, quality of the data, depression severity and evaluations about attentions deficit hyperactivity disorder were considered. Data were analyzed with T test, Mann-Whitney U test, Welch ANOVA, Kruskal Wallis test, Pearson test, Spearman test, ANOVA and ANCOVA by using SPSS Statistics 22.0. Significance level was set as p
- Published
- 2018
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