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Objective: To determine the prevalence of hepatic steatosis and whether there is an association with pulmonary involvement in CT scans of patients with COVID-19. Material and methods: 140 patients with positive PCR for SARS-CoV-2 and with simple chest tomography were evaluated. The tomographic findings of COVID-19 were evaluated by the CO-RADS system, pulmonary involvement was classified with the proposed INER scale and hepatic steatosis was determined at 42 UH. The SPSS program was used for statistical analysis with X2 test. Results: Out of 140 patients we found 91 men (65%) and 49 women (65%). The most affected age was 60.9 ± 15 years. The prevalence of hepatic steatosis was 32.1%, no association was found with the degree of pulmonary involvement by X2 test (p = 0.151). Obesity was observed in 37.1%, overweight in 36.4%, arterial hypertension in 35.7% and diabetes mellitus in 21.8%. Conclusions: There is no association between hepatic steatosis and pulmonary involvement in COVID-19 pneumonia. The prevalence of hepatic steatosis of 32.1% is similar to that reported in other studies. [ABSTRACT FROM AUTHOR]

Objective: To describe the clinical and laboratory data, with special emphasis on thoracic imaging findings, in 14 patients with a definitive diagnosis of granulomatosis with polyangiitis (GPA). Methods: The clinical and tomographic data of 14 patients with a definitive diagnosis of GPA are presented. Patients with thoracic manifestations suggestive of GPA were evaluated in 3 hospitals from 2000 to 2012. All patients had a sputum analysis and bronchoalveolar lavage for bacterial, mycobacterial and fungal stains and cultures; antineutrophil cytoplasmic antibodies, antinuclear-antibodies, rheumatoid factor, and a biopsy of involved organs. Results: A total of 13 patients had at least two organs involved. The most frequent thoracic findings were pulmonary nodules, ground glass opacities and patches of consolidation; other abnormalities were tracheal stenosis, diffuse alveolar hemorrhage, lung masses with organized pneumonia. More than three- quarters (78%) of patients had positive antineutrophil cytoplasmic antibodies (ANCA). Ten patients had respiratory tissue biopsy (8 open lung, one tracheal, and one nasal). In 4 patients the diagnosis was made with the classic organ involvement in GPA, positive ANCA, and renal or skin biopsy, and response to treatment on follow-up. At 6-12 months all patients showed clinical and radiological improvement, with 54% showing a recurrence of disease. Discussion: The majority of thoracic findings described in GPA are presented in this study. A complete diagnostic approach with invasive diagnostic procedures to rule out other more prevalent respiratory diseases with similar thoracic manifestations must be performed. The positivity of ANCA in this study was high, and the recurrence of the disease was frequent. [ABSTRACT FROM AUTHOR]