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Primary Amoebic Meningoencephalitis, is an infectious disease quickly progressive it affects to patients immunocompetent, caused by free living amoeba (Naegleria fowleri, Acantamoheba spp and Balamuthia mandrilaris) condition an acute, necrotizing and hemorrhagic process that progresses to brain edema, coma and dead. "Uncommon Disease", however, her real incidence is unknow, because is underreporting arid overlapping with viral or bacterial meningoencephalitis; also il diagnosis is fact postmortem, and is limited by low number of autopsies in most countries. Contribute to mortality the ineffective treatment and common exposing in cotidian activities, recreational and religious to the agent. We present a case report of paediatric patient two years old, with atactic march, paralysis of the sixth pair of 30 days, rapid deterioration, she dead a month after her hospitalization with diagnosis postmortem of Primary Amoebic Meningoencephalitis. [ABSTRACT FROM AUTHOR]

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