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Objetive: To determine the frequency of Helicobacter pylori infection and describe the clinical characteristics of children with upper endoscopy from the service of Gastroenterology - Hospital Nacional Almanzor Aguinaga Asenjo - ESSALUD: 2007 - 2010. Materials and Methods: Retrospective, descriptive study in which the medical records and the endoscopy sheet of 93 patients younger than 18 years, were reviewed. Descriptive statistics was used. The processing of data was using Microsoft Excel 2010 and 10.0th STATA version. Results: There were 93 patients of whom 60 were women (64.52%) and 33 males (35.48%). The mean age was 12 +/- 4 years. The frequency of Helicobacter pylori infection was 68.82%. In patients with Helicobacter pylori infection the primary indication for endoscopy was "gastritis" followed by nonspecific abdominal pain. In HP positive patients, the principal indication for endoscopic was "gastritis" 50.54%, follow with Abdominal recurrent pain with 24.73%. The most frequent endoscopic diagnosis in HP patients was nodular gastritis: 31 patients (33.33%), the main histopathological finding was moderate chronic follicular gastritis: 55 patients (59.14%). Association between Nodular gastritis (p.0,044) and Chronic folicular moderate Gastritis (p< 0,001) with the presence of Helicobacter pylori, was found. Conclusions: Helicobacter pylori infection in children under 18 years was very frequent, being Nodular gastritis and Chronic follicular moderate gastritis the endoscopic and biopsy findings, more frequently found. We found an association within Helicobacter pylori infection with Nodular gastritis and Chronic moderate follicular gastritis. [ABSTRACT FROM AUTHOR]

Introduction: all of the available tests for the diagnosis of H. pylori have differences in their sensibility and specificity. The purpose of this study is to determine the developmental index, sensibility, specificity and predictable values of four invasive methods, using the case definition as a referential technique; positive culture o concordance of at least two processes of positive diagnostics. Methods: five biopsies were taken among seventy two patients, distributed for PCR-ureC, culture, quick ureic test (PRU) and histological examination (EH). Results: the developmental index (ID), sensibility, specificity and predictive measures showed differences. The couple EH-PCF was considerably effective, presenting the greatest values of analyzed indexes. The prevalence of infection was of 86.1%. Conclusion: in order to establish the true status of the infection by H. pylori, it is necessary to use the criteria by case definition. [ABSTRACT FROM AUTHOR]

Objectives. To compare gastric biopsies immediately fixed with 10% formalin with biopsies fixed after 24 hours for the detection of Helicobacter pylori (Hp) in a reference hospital in Peru. Materials and methods. A diagnostic test study on gastric biopsies from 72 patients attending the Gastroenterology service of hospital Essalud Alberto Sabogal in Callao was performed. Samples from each patient were divided into two glass jars, one of which was fixed immediately with 10% formalin and the other was fixed after 24 hours. Both groups of samples were processed with the conventional technique of paraffin embedding and staining with hematoxylin-eosin. Results. Hp was found in 56.9% of the group of biopsies which were inmediatly fixed and in 79.2% of the group of biopsies fixed after 24 hours, showing statistical difference (p <0.001). Conclusions. There is an increased frequency of diagnosis of Hp in the samples that were fixed after 24 hours, which may suggest that this would act as a biological culture for Hp, which would facilitate its diagnosis. [ABSTRACT FROM AUTHOR]