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Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Se presenta una reimpresión del artículo "Dos casos de síndrome de Sheehan" de Javier Soberón, publicado en la revista "Ginecología y Obstetricia de México", no. 14, año 1959. El artículo discute dos casos de mujeres mexicanas afectadas por síndrome de Sheehan, incluyendo referencias a los medios de diagnóstico, su presencia como factor de riesgo en complicaciones del embarazo y anatomía de la hipófisis o glándula pituitaria.

Introduction: postpartum pituitary necrosis, or Sheehan's syndrome, occurs following obstetric haemorrhage which causes intense circulatory collapse, thereby predisposing pituitary ischemia leading to this organ becoming enlarged (the posterior pituitary is generally affected). This document presents a clinical case of a patient who consulted due to late manifestations of this syndrome. A literature review is also made. Objective: presenting the case of a patient who consulted for late manifest at ions of Sheehan's syndrome and reviewing the pertinent literature. Methodology: information was sought in the PubMed / Medline, Cochrane, SciELO databases and references from articles in journals and texts (mainly from the last five years) were also taken into account. The seven most relevant articles were taken according to the impact of the journal in which they were published. Results: the most frequently found clinical characteristic was an inability to lactate due to insufficient prolactin production. The most common clinical feature found was an inability to breastfeed due to insufficient prolactin production. Other manifestations included inappropriate antidiuretic hormone secretion and cortisol, thyroid hormone and gonadotropin secretion deficiencies. Obstetricians and GPs should be able to recognise this syndrome and know about its management as the acute loss of adenohypophysis functioning may have a poor prognosis without timely and suitable hormone replacement. Good hormone control prevents or decreases metabolic and cardiovascular complications. Conclusion: this is a rare syndrome in which early diagnosis is difficult and requires hormone replacement therapy with ongoing clinical and laboratory controls. [ABSTRACT FROM AUTHOR]

El texto ofrece un comentario del artículo "Dos casos de síndrome de Sheehan" de Javier Soberón, publicado en la revista "Ginecología y Obstetricia de México", no. 14, año 1959 y reproducido en la presente edición. Algunos temas discutidos incluyen las investigaciones sobre panhipopituitarismo realizadas a principios del siglo XX, la ausencia de caquexia como síntoma y anatomía de la glándula pituitaria.