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OBJECTIVE: To evaluate the effect of intratympanic treatment with brain-derived neurotrophic factor embedded in collagen sponge and simultaneous oral administration of N-acetylcysteine (NAC) with amikacin on oxidative stress through glutathione peroxidase expression, audiological and histological changes in the cochlea of guinea pigs with ototoxicity caused by amikacin. MATERIALS AND METHODS: Fifty-five guinea pigs were included, in 50 ototoxicity occurred due to amikacin, they were divided into 5 groups of 10 animals each and were treated as follows: group I: without treatment, group II: post-hearing NAC, group III: simultaneous NAC-amikacin, group IV: saline solution and group V: brainderived neurotrophic factor. The animals were evaluated for 4 weeks with otoacoustic emissions by distortion products. Cochlear integrity was evaluated histologically and glutathione peroxidase production was evaluated immunohistochemically. Study was done from January 1st, 2022 to January 31, 2023. RESULTS: None of the animal reverted hearing loss. Histologically, groups I, II, III and IV showed severe loss of hair cells and mild in group V. In group I glutathione peroxidase production was severe; moderate in II, III and IV, and mild in V. CONCLUSIONS: Simultaneous and post-hearing loss treatment for NAC and intratympanic application of brain-derived neurotrophic factor do not prevent glutathione peroxidase production in guinea pigs with ototoxicity caused by amikacin, but they decrease it. [ABSTRACT FROM AUTHOR]

Objective: To determine the association between frailty syndrome and family functioning among older adults with diabetic retinopathy. Materials and methods: An analytical and cross-sectional study conducted among patients diagnosed with diabetic retinopathy. The ophthalmology department diagnosed diabetic retinopathy through pupil dilation, using tetracaine and an ophthalmoscope. Three groups were determined using the FRAIL questionnaire: frail, prefrail and nonfrail; the sample sizes were 39, 64 and 76, respectively, matched by age. The study variables included age, sex, education, marital status and occupation. Additionally, the time since the diagnosis of diabetic retinopathy was measured. Furthermore, the type of family was determined according to Huerta's classification, which identifies nuclear family, extended family, composite extended family, single-parent family and blended family. Family functioning was evaluated with the FF-SIL questionnaire. The statistical analysis included the chi-square test. The protocol was registered with the research and ethics committee of the health institution, and surveys were administered after obtaining prior informed consent. Results: The median ages in the frail (73 years), prefrail (71 years) and nonfrail (70 years) groups were statistically similar (p = 0.061). The prevalence of living as a couple was 23.1 % in the frail group, 48.4 % in the prefrail group and 60.5 % in the nonfrail group, with statistically significant differences among these groups (p = 0.001). There was an association between frailty syndrome and type of family functioning: in the nonfrail group, 88.2 % had a functional family, compared to 46.9 % in the prefrail group and 15.4 % in the frail group (p = 0.000). Conclusions: There is an association between frailty syndrome and family functioning among geriatric patients with diabetic retinopathy. [ABSTRACT FROM AUTHOR]

Copyright of Aula Abierta. Revista de Investigación, Formación e Innovación en Educación (RIFIE) is the property of Universidad de Oviedo, Servicio de Publicaciones and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Anales de Otorrinolaringología Mexicana is the property of Sociedad Mexicana de Otorrinolaringologia y Cirugia de Cabeza y Cuello and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Dilemas Contemporáneos: Educación, Política y Valores is the property of Dilemas Contemporaneos: Educacion, Politica y Valores and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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The rapid development of information and communication technologies (ICT) has opened new possibilities for teaching and assessment practices in higher education, including computerbased assessment (CBA). Since the effective development of this depends on student acceptance, the present study analyzed the constructs that affect the intention to use CBA through the computer-based assessment acceptance model (CBAAM) at a private university in Mexico. The methodology was quantitative and divided into two phases: 1) application of an assessment with multiple-choice questions with automatic grading, and 2) testing of the measurement and structural model of the CBAAM instrument with 84 first-semester engineering students. The results indicate that playful perception has a direct effect on the use of CBA, while facilitating conditions, computer self-efficacy, perceived ease of use, goal expectation, social influence, and content only have indirect effects. The acceptance model studied explains approximately 47% of the variation in the intention to use. It is recommended to investigate other variables that affect the purpose of use and to apply the model in other contexts for further confirmation. [ABSTRACT FROM AUTHOR]

Copyright of Universitas, Revista de Ciencias Sociales y Humanas is the property of Universidad Politecnica Salesiana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of REMIE - Multidisciplinary Journal of Educational Research is the property of Hipatia Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archivos de Cardiología de México is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Insurance companies play an important role in a healthy economy, providing a security service for goods and people. The Venezuelan insurance market has faced great challenges in recent decades, in a tight environment where knowing the closest competitors is of paramount importance. The public body that regulates the comparison between insurers has only used the premiums charged as a categorization factor, an additional set of indicators is published. In this study, we make use of five of these indicators used over the last three years and test whether the premiums charged represent a unique ranking characteristic. The vast repertoire of machine learning is able to cope with the significant increase in the number of study variables and their possible groupings. The multivariate analysis of these 18 variables has required the use of the factor analysis method, which allows dimensionality reduction of highly correlated factors. With these new factors, clustering classification is sought using the unsupervised K-Means and Fuzzy C-Means algorithms, comparing their derived clusters with respect to whether the premiums charged represent a determinant clustering characteristic. [ABSTRACT FROM AUTHOR]

The idea of classicism is one of the most used categories in the world of the arts and of philosophical aesthetics. However, the variety of its uses has caused the term to present difficulties of interpretation and ambiguities to those who study classicist art or literature. This paper intends to introduce some clarity and distinctness in the discussion about the idea of classicism. To do this, we first deal with the questions that concern its historical genesis, dissociating it from the similar, but essentially different, concept of the classical. Second, we offer a characterization of its structure through a systematization of its four main senses as they are commonly used in the bibliography on the subject. In this way, classicism presents itself to us as the problem of articulating the different philosophical conceptualizations that have been adopted about the classical. [ABSTRACT FROM AUTHOR]

This manuscript provides insights about the persistence of peasant life in Los Chenchos, a riverine community in the Colombian Pacific. Following a social wellbeing approach, we examine the material, relational and subjective dimensions underlying the persistence of this community in their ancestral territory despite profound social and economic challenges marked by regional land use change and the emergence of illegal and extractive economies. We followed a sequential mixed-methods approach based on participant observation, ethnographic interviews and a descriptive census of the three dimensions of social wellbeing in the 18 households that make the community. Employing the social wellbeing approach provided an understanding of how achieving a desired way of life is an adaptive response that draws on values associated with small-scale agricultural production and family networks. [ABSTRACT FROM AUTHOR]

The quality of tourism services is a crucial element for the development and growth of companies; globalisation implies the need for information for decision-making in a competitive world. This research aimed to analyse the dimensions and criteria of the quality of service offered by tourism providers in the Magical Town of El Fuerte, Sinaloa. The methodology is quantitative, descriptive and cross-sectional. It is based on an analysis of the perception of the service provided using five dimensions with different criteria established in the SERVQUAL model and analysed under the SERVPERF model. A total of 383 surveys were applied to tourists and visitors who consumed services in the different establishments; the instrument consists of 24 items: 22 of them to evaluate the quality of service and two to know the price-service relationship and quality of service in general on a Likert scale; the application period was during April and May 2023. The results indicate that empathy, assurance, and responsiveness were the best evaluated of the five dimensions analysed for service quality. The majority of respondents perceive the quality of service as excellent, which indicates that the tourist destination provides acceptable conditions for the experience. However, the results are a tool for decision-making aimed at continuous improvement in the criteria evaluated. [ABSTRACT FROM AUTHOR]

Copyright of Revista Venezolana de Gerencia (RVG) is the property of Revista de Filosofia-Universidad del Zulia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Dictamen Libre is the property of Universidad Libre Seccional Barranquilla and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Espacio, Tiempo y Forma. Serie III, Historia Medieval is the property of Editorial UNED and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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The article "Juan Filloy in the 1930s" presents an exhaustive investigation of the work of Argentine writer Juan Filloy during the 1930s. The author, Martina Guevara, analyzes the novels published by Filloy in that decade and his contribution to the debates on national identity during that period. Guevara highlights Filloy's ability to mix literary genres in his works, such as detective fiction and essays. Guevara's book offers an innovative and detailed look at Filloy's work, challenging superficial interpretations and highlighting his importance in Argentine literature. [Extracted from the article]

Copyright of Revista Hidalguía is the property of Revista Hidalguia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Hidalguía is the property of Revista Hidalguia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This paper analyzes the discourse on migration from the official Twitter accounts of 5 political parties in Spain (PSOE, PP, Podemos, Ciudadanos and Vox), during the so-called «migration crisis» that took place in Ceuta in May 2021. The methodology followed allows us to describe the activity of the different political party accounts, the centrality of the migration issue in them, the topics and discursive strategies contained in the publications and their engagement. The findings of the work carried out point to the existence of a hardening of the political discourse on immigration in the context studied, accompanied by a loss of «political correctness» -characteristic of previous times- to address migration issues, which only alerts us to the normalization of racist hate speech in the network considered. [ABSTRACT FROM AUTHOR]

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The purpose of this work is to show how medicine has been intertwined with the arts from its origin, and how this relationship has made it possible to illustrate through its expressions the activities performed by the doctor in the clinic, and in the medical lessons captured in various works throughout history, this connection has influenced the form of expression of one and the other over time; medical and daily life events were captured in different periods of prehistory and history, and their artists became the chroniclers of the most relevant events that occured in a certain place. From the appearance of the first hospitals in the Middle Ages there are artistic representations on their walls, originally with religious or mystical topics and later with medical themes until reaching the large murals captured in the hospitals of the first half of the twentieth century such is the case of Mexico where they have remained as evidence of the connection between art and medicine and have brought knowledge of the history of medicine to the experts in health sciences and to the general public. [ABSTRACT FROM AUTHOR]

Copyright of Aposta is the property of Aposta and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition) is the property of Ibanez y Plaza and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Solitary fibrous tumour (SFT) is a mesenchymal-derived malignant neoplasm, it can occur anywhere in the body. Lüttges et al. first described TFS affecting the pancreas. There are currently approximately 30 published cases worldwide. Case presentation: we present the case of a female patient who presented for evaluation during her puerperium due to poorly characterized epigastric discomfort and early satiety. Imaging studies revealed a lesion at the level of the pancreatic body. An attempt was made to document the etiology by biopsy, with inconclusive results, so a distal pancreatectomy was performed for diagnosis and treatment. Pathology showed solitary fibrous tumor of the pancreas. These tumors pose a diagnostic challenge at the histopathological level, so it is essential to perform immunohistochemistry to obtain an accurate diagnosis. We performed immunohistochemistry for NAB2-STAT6 showing the positivity of the test and thus establishing the diagnosis. At the molecular level the NAB2-STAT6 gene fusion encodes a protein with transcriptional activation for EGFR families, thus driving carcinogenesis. Other cases have shown association of TFS with pregnancy, however, in our case the tumor did not express hormone receptors. Conclusion: We present a clinical case with a diagnosis of solitary fibrous tumor of the pancreas, demonstrating the indispensability of immunohisto chemical tests for diagnosis. STAT6 positivity is currently the gold standard for this type of tumor. The patient is currently being followed up with no clinical or imaging data suggestive of tumor activity. [ABSTRACT FROM AUTHOR]

Copyright of Salud Uninorte is the property of Fundacion Universidad del Norte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Gaceta Médica de México is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Revista Española de Orientación y Psicopedagogía (REOP) is the property of Revista Espanola de Orientacion y Psicopedagogia (REOP) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Oesophagostomum venulosum is a gastrointestinal nematode (GIN) whose hosts are mainly sheep and goats. In Argentina, the presence of this parasite is reported in all regions of the country, mainly in sheep. In the Argentine Northwest (NOA) it is reported in cattle and camelids. The objective of this work was to describe for the first time the presence of O. venulosum in goats from the NOA region. In March 2023, the INTA Salta Specialized Veterinary Diagnostic Service made a diagnostic visit to a Criolla breed goat breeding facility, located near the capital city of Salta, Argentina. The reason for the visit was due to the death of a goat that, according to the account of the owner, prior to her death, presented symptoms of colic and dyspnea, with progressive loss of body condition. Given the suspicion of a parasitic condition, it was decided to collect the digestive tract for the determination of adult specimens. It was possible to observe the presence of Haemonchus contortus in the abomasum, of Trichostrongylus colubriformis in the small intestine, and of O. venulosum in the colon. The finding of O. venulosum in caprines adds to the reports of said NGI in other animal species of zootechnical interest in the NOA, and is, to our knowledge, the first description in caprines nationwide. [ABSTRACT FROM AUTHOR]

Copyright of Profesorado: Revista de Currículum y Formación del Profesorado is the property of Profesorado: Revista de Curriculum y Formacion del Profesorado and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)