Introduction: The clinical simulator, specifically the simulated patient, generates a significant learning and an approach to reality, preparing the undergraduate student for better performance and quality in the care. Objective: To evaluate the influence of the use of the simulated patient to get a meaningful learning of the content about the procedure "wound healing" and how this learning has been used in the clinical practice. Materials and Methods: A quantitative, comparative quasi-experimental study was designed. The use of the simulated patient was implemented in a group of 60 students from the first year of the nursing degree; while in another group, also of 60 students, traditional teaching was used. Subsequently, in clinical practice, the execution of the procedure was evaluated against real patients in both groups. Results: Concerning the student's perception, it was found that both groups reported the importance of the use of specific instructional strategies such as simulation. There were significant differences between groups in knowledge level, skills, and procedure execution. The execution improved in the intervention group. Conclusions: The students perceive the difference between the two methods. However, they say that it is better to continue teaching by repetition (traditional). They diminish abilities acquired in analogous practice, especially that carried out by simulators. However, when facing the real patient's attention, those who used the simulator perform the procedures better. [ABSTRACT FROM AUTHOR]