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The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a virus that has spread around the world, causes an acute respiratory infection and it may also cause death. The damage that can cause in other organs is frequent. Many studies had also shown alterations in liver function tests, that are then related to serious illness and with hospitalization requirements. Moreover, in patients infected with the virus that had underlying liver disease, a significant increase in the level of aminotransferases was observed in the course of the disease. A greater risk of serious illness was also detected. The pathophysiological explanation of liver injury in those patients covers the direct cytopathic effect produced by binding the virus, the angiotensin-converting enzyme (ACE2) to the hepatocytes and the cholangiocytes, excessive immune response, and in some cases, drug-induced hepatotoxicity. [ABSTRACT FROM AUTHOR]

The case report of a 20 years nulliparous pregnant woman with history of intermittent, asymptomatic asthma is presented, who was admitted with an icteric syndrome in "Mariana Grajales Coello" Gynecoobstetric Hospital of Santiago de Cuba. After carrying out him the pertinent studies it was concluded that she presented a complicated hepatitis E, which required intensive cares; with the opportune diagnosis and the effective treatment her survival could be guaranteed. [ABSTRACT FROM AUTHOR]

Caso clínico: presentamos una paciente de 33 años con anorexia nerviosa de 15 años de evolución con uno de los pocos casos reportados de fallo hepático agudo severo secundario a la desnutrición.Discusión: tras el soporte nutricional protocolizado para evitar el síndrome de realimentación y un adecuado manejo multidisciplinar, la paciente evoluciona favorablemente logrando normalizar los electrolitos, la función hepática y las alteraciones en la coagulación. [ABSTRACT FROM AUTHOR]

Introduction: Orthotopic liver transplantation is currently the treatment of choice for patients with end-stage liver disease. Vascular complications can trigger a failure of treatment, so it must be watched closely. Clinical, diagnostic evaluation and interventions We report the case of a patient undergoing three times for liver transplantation for recurrent thrombosis of the hepatic artery. After the third transplant perfusion defect persists, despite which the short-term evolution was favorable. Conclusion: The clinical presentation of hepatic artery thrombosis are variable, but usually require early and aggressive management. [ABSTRACT FROM AUTHOR]

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A new clinical scenario called Occult Hepatitis C Virus infection has been recently described (HCV-Oc); it can only be characterized by molecular analysis, due that serological marker by ELISA are not detected. The aim of the present study was to identify the Hepatitis C Virus infection in a patient re-transplanted by hepatic failure of unknown etiology. For this, RNA obtained from different sources (Liver tissue, serum, plasma and buffy coat) was assessed by a RT-PCR protocol that specifically targeted the HCV 5'UTR, showing the presence of HCV genome just in liver tissue explants. When viral sequences were analyzed, the strains belonged to HCV genotype 1a. Our study corresponds to the first report in the world of HCV-Oc due to HCV genotype 1a, in liver retransplantation context. We recommend having in mind this new clinical scenario into the differential diagnosis of patients with cirrhosis, hepatocellular carcinoma and/or hepatic failure of unknown etiology. [ABSTRACT FROM AUTHOR]

Cytomegalovirus disease is common in the Mexican population, in general with 80% of survival, but in adults is asymptomatic and when present in children tends to be acute and self-limited course. However, in this patient was aggressive conditioning fulminant hepatic failure and death of the patient, showing that the patient does not have any immunodeficiency. Diagnosis is confirmed by serology and bone marrow aspiration. [ABSTRACT FROM AUTHOR]

Background: chronic alcoholic liver disease (EHAC) associates to recurrent pleural effusion. Generally thoracocentesis is not performed for considering this fluid a trasudate. Our objective was to determine the usefulness of thoracocentesis and causes of recurrent pleural effusion. Methods: we analyzed samples of pleural fluid of patients with chronic alcoholic liver disease, recurrent pleural effusion and respiratory failure. Blood tests, chest x-rays and pleural fluid analyses were evaluated. Results: we included 27 cases. Mean age of patients was > 60 year old, mean evolution time of liver disease was ~ 4 years. 55.6 % were exudates and 44.4 % trasudates. Causes of recurrent pleural effusion were portal hypertension in 12 (44.4 %) cases. In patients with exudate, the origin was infectious in 8 (29.6 %) cases; in 4 (14.8 %) the cause was malignancy; one more with pulmonary embolism, and in other two patients the cause was not identified. Conclusions: we found that more than half of patients with chronic alcoholic liver disease and recurrent pleural effusion was an exudate, thus thoracocentesis should be frequently performed in these patients. [ABSTRACT FROM AUTHOR]