1. ACTUALIZACIÓN EN COVID-19 Y SISTEMA DIGESTIVO.
- Author
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Daoud, Georgette, Navarro, Dianora, Colina, Nina, and López, Karolina
- Abstract
From the begining of the coronavirus (sAr-cov-2) pandemia in december 2019, the world cientific information has been very dynamic in the clinical presentation, fisiopathology and the treatment of this infection. there are few prospective published studies and many in process. two receptores the angiotensin converting enzyme 2 (Ace2) and the transmembrane serine protease 2 (tMPrss2).has been determined for the viral entrance and fusion to the gastrointestinal epithelial cells. the gastric ph inhibitory viral role has been enphasized. the alteration of the microbiota (disbiosis) has emerged due to its important effect on the clinical susceptibility and severity progression of the covId-19 patient, related with the intestine-lung axis, which is the cross talk and exchange of inflammatory mediator between the intestine and the lung, through blood and lymphatic circulation, migrate to the intestine and bind to the Ace2 receptores highly expressed in the enterocyts. the most frequent digestive manifestations are anorexia and taste alterations, diarrhea, nausea, vomiting, hiccup and abdominal pain. nowaday, new therapeutic strategies are mainly foccused on the immune system stimulation with prebiotics, probiotics and some micronutrients, including vitamins c, d, e, zinc and omega 3, among others. It concludes, thar the digestive system is the second organ most affected after the respiratory system and the gstrointestinal manifestations are more common in the pediatric age, with more viral fecal excretion, which sholud be kept in mind for preventive reccomentations. [ABSTRACT FROM AUTHOR]
- Published
- 2020