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Copyright of Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica is the property of Asociacion Colombiana de Dermatologia y Cirugia Dermatologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The reactive oxygen and nitrogen species are molecules that are generated from the physiological cellular metabolism. However, when there is an imbalance between the production of free radicals and the antioxidant mechanisms, oxidative stress is generated. Oxidative stress has been associated with the development and progression of neurodegenerative diseases such as Alzheimer, Parkinson and Huntington, given that the onset of oxidative stress is imperceptible and that there are still no laboratory studies that can determine the impact of free radicals in patients with neurodegenerative diseases. It is important to elucidate the role of free radicals in neurodegenerative processes in order to have solid indications about the possible treatment targets and to prevent the progressive damage in this type of diseases. [ABSTRACT FROM AUTHOR]

Copyright of Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica is the property of Asociacion Colombiana de Dermatologia y Cirugia Dermatologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The tuberculous gumma is a rare cutaneous manifestation of tuberculosis that occurs as a result of hematogenous spread. The microbiological isolation of the organism may be difficult, so in the setting of a very suspicious case in the absence of microbiological confirmation, we suggest to start empirical antimicrobiological therapy and to assess the answer to it. We report a case of tuberculosis gumma as a cutaneous manifestation of disseminated tuberculosis with pulmonary and bone involvement, with an adequate response to tuberculosis treatment. [ABSTRACT FROM AUTHOR]

Copyright of Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica is the property of Asociacion Colombiana de Dermatologia y Cirugia Dermatologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cutaneous metastasis from internal malignancies are rare especially those with zosteriform pattern. We report the case of a female patient with a colonic adenocarcinoma stage IV, who presented metastasis to her right thigh that mimicked herpes zoster. Prognosis of patients with cutaneous metastasis from internal malignancies is poor. [ABSTRACT FROM AUTHOR]

A 43 years old female patient presented with erythematous macules, located in the buttocks, abdomen and extremities that quickly evolved into large areas of ulceration and necrosis. After an exhaustive study of the case with the haematologist and based on clinical, paraclinical and histological findings the diagnosis of a cryoglobulinemia secondary to a B cell lymphoma was made. [ABSTRACT FROM AUTHOR]