1. A case report of prucalopride treatment in pediatric gastroparesis: a novel therapy.
- Author
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Escobar-Serna DP, Peralta-Palmezano FJ, and Peralta-Palmezano JJ
- Subjects
- Adult, Child, Domperidone therapeutic use, Gastric Emptying, Humans, Male, Benzofurans therapeutic use, Gastroparesis diagnosis, Gastroparesis drug therapy
- Abstract
Prucalopride has been used in adults with gastroparesis, accelerating gastric emptying. There are no studies with this drug in gastroparetic children. An 8-year-old boy is presented who consulted for a month of postprandial symptoms, with a diagnosis of gastroparesis by gastric emptying scintigraphy. He did not improve with metoclopramide, domperidone, erythromycin, and esomeprazole. He received prucalopride for two periods (for 178 and 376 days) at doses: 0.03 - 0.04 mg/ kg/day, presenting improvement in the follow-up with the cardinal gastroparesis symptom index and gastric emptying scintigraphy. Due to the good response, prucalopride may be a therapeutic option in pediatric gastroparesis.
- Published
- 2022
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