17 results on '"Rangel-Sousa, Diego"'
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2. Uso de un sistema extracorpóreo de asistencia circulatoria de flujo continuo, corta duración e inserción quirúrgica como puente a trasplante
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Cabezón-Villalba, Gonzalo, Barge-Caballero, Eduardo, González-Vílchez, Francisco, Castel-Lavilla, María Ángeles, Gómez-Bueno, Manuel, Almenar-Bonet, Luis, González-Costello, José, Lambert-Rodríguez, José Luis, Martínez-Sellés, Manuel, de la Fuente-Galán, Luis, Mirabet-Pérez, Sonia, García-Cosío Carmena, María Dolores, Hervás-Sotomayor, Daniela, Rangel-Sousa, Diego, Blasco-Peiró, Teresa, Garrido-Bravo, Iris P., Rábago Juan-Aracil, Gregorio, Muñiz, Javier, and Crespo-Leiro, María G.
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- 2024
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3. Asistencia ventricular de larga duración en España (2007-2020). I informe del registro REGALAD
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Gómez-Bueno, Manuel, Pérez de la Sota, Enrique, Forteza Gil, Alberto, Ortiz-Berbel, Daniel, Castrodeza, Javier, García-Cosío Carmena, María Dolores, Barge-Caballero, Eduardo, Rangel Sousa, Diego, Díaz Molina, Beatriz, Manrique Antón, Rebeca, Almenar-Bonet, Luis, Uribarri González, Aitor, Barrio-Rodríguez, Alfredo, Castel Lavilla, María Ángeles, López-López, Laura, Dobarro Pérez, David, Pastor Pérez, Francisco, Burgos-Palacios, Virginia, Álvarez-García, Jesús, Garrido-Jiménez, José Manuel, González-Fernández, Óscar, Codina, Pau, López-Granados, Amador, Grau-Sepulveda, Andrés, and González-Costello, José
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- 2023
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4. Complicaciones infecciosas relacionadas con la asistencia circulatoria mecánica de corta duración en candidatos a trasplante cardiaco urgente
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Solla-Buceta, Miguel, González-Vílchez, Francisco, Almenar-Bonet, Luis, Lambert-Rodríguez, José Luis, Segovia-Cubero, Javier, González-Costello, José, Delgado, Juan F., Pérez-Villa, Félix, Crespo-Leiro, María G., Rangel-Sousa, Diego, Martínez-Sellés, Manuel, Rábago-Juan-Aracil, Gregorio, De-la-Fuente-Galán, Luis, Blasco-Peiró, Teresa, Hervás-Sotomayor, Daniela, Garrido-Bravo, Iris P., Mirabet-Pérez, Sonia, Muñiz, Javier, and Barge-Caballero, Eduardo
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- 2022
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5. Registro Español de Trasplante Cardiaco. XXXII Informe Oficial de la Asociación de Insuficiencia Cardiaca de la Sociedad Española de Cardiología
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Cobo-Belaustegui, Manuel, Llano-Cardenal, Miguel, Vázquez de Prada, José Antonio, Nistal-Herrera, Francisco, Lambert-Rodríguez, José Luis, Díaz-Molina, Beatriz, Fidalgo-Muñiz, Cristina, Rangel-Sousa, Diego, Grande-Trillo, Antonio, Brossa-Loidi, Vicens, Mirabet-Pérez, Sonia, López, Laura, Zegrí, Isabel, de Antonio, Marta, Castel, María Ángeles, Farrero, Marta, Manito, Nicolás, Díez, Carles, García-Romero, Elena, Roca, Josep, Castrodeza, Javier, Sousa, Iago, Blázquez, Zorba, Zataraín, Eduardo, García-Carreño, Jorge, Navas, Paula, Juárez, Miriam, Ortiz, Carlos, Martínez-Sellés, Manuel, Cebrián, Mónica, López-Viella, Raquel, Sánchez-Lázaro, Ignacio, Martínez, Sol, Donoso, Víctor, Martínez, Luis, López-Granados, Amador, Segovia-Cubero, Javier, Hernández-Pérez, Francisco, Mitroi, Cristina, Rivas-Lasarte, Mercedes, García-Cosío, María Dolores, Morán-Fernández, Laura, Caravaca, Pedro, López-Azor, Juan Carlos, Paniagua-Martín, María Jesús, Barge-Caballero, Eduardo, Barge-Caballero, Gonzalo, Couto-Mallón, David, Cuenca-Castillo, José, Herrera-Noreña, José María, García-Guereta Silva, Luis, González-Fernández, Óscar, Ponz de Antonio, Inés, Labrandero de Lera, Carlos, González-Rocafort, Álvarez, Polo-López, Luz, Camino-López, Manuela, Gil-Villanueva, Nuria, de la Fuente-Galán, Luis, Tobar-Ruiz, Javier, Garrido-Bravo, Iris P., Pascual-Figal, Domingo A., Pastor-Pérez, Francisco J., Blasco-Peiró, Teresa, Pórtoles-Ocampo, Ana, Lasala-Alastuey, María, Rábago-Juan-Aracil, Gregorio, Manrique-Antón, Rebeca, Jimeno-San Martín, Leticia, García-Quintana, Antonio, Groba-Marco, María del Val, Galván-Ruiz, Mario, Gran-Ipiña, Ferrán, Dolader, Paola, González-Vílchez, Francisco, Almenar-Bonet, Luis, Crespo-Leiro, María G., Gómez-Bueno, Manuel, González-Costello, José, Pérez-Villa, Félix, Delgado-Jiménez, Juan F., Arizón del Prado, José M., Sobrino-Márquez, José M., and Valero-Masa, María Jesús
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- 2021
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6. Registro Español de Trasplante Cardiaco. XXXI Informe Oficial de la Asociación de Insuficiencia Cardiaca de la Sociedad Española de Cardiología
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Segovia-Cubero, Javier, Hernández-Pérez, Francisco, Martínez Penades, Soledad, Cebrián Pinar, Mónica, López Vilella, Raquel, Sánchez-Lázaro, Ignacio, Martínez-Dolz, Luis, Paniagua-Martín, María J., Barge-Caballero, Eduardo, Barge-Caballero, Gonzalo, Couto-Mallón, David, López Granados, Amador, Segura Saintgerons, Carmen, Menjíbar Pareja, Víctor, Carrasco Ávalos, Francisco, Cobo, Manuel, Llano-Cardenal, Miguel, Vázquez de Prada, José A., Nistal Herrera, Francisco, Blázquez, Zorba, Jesús Valero, María, Ortiz, Carlos, Zataraín, Eduardo, Villa, Adolfo, Navas, Paula, Martínez-Sellés, Manuel, Dolores García Cosío, M., Morán Fernández, Laura, Caravaca, Pedro, Brossa Loidi, Vicens, Roig Minguell, Eulàlia, Mirabet Pérez, Sonia, López López, Laura, Zegrí, Isabel, Rangel Sousa, Diego, Manito Lorite, Nicolas, Díez Lopez, Carles, Roca Elias, Josep, García Romero, Elena, Rábago Juan-Aracil, Gregorio, Castel, María Ángeles, Farrero, Marta, Lambert Rodríguez, José Luis, Díaz Molina, Beatriz, Bernardo Rodríguez, María José, Fidalgo Muñiz, Cristina, Camino López, Manuela, Gil Jaurena, Juan Miguel, Gil Villanueva, Nuria, Garrido-Bravo, Iris, Pascual Figal, Domingo A., Pastor Pérez, Francisco J., Blasco-Peiró, Teresa, Portoles Ocampo, Ana, Sanz Julve, Marisa, de la Fuente Galán, Luis, Tobar Ruiz, Javier, Recio Platero, Amada, García-Guereta Silva, Luis, González Rocafort, Álvaro, Labradero de Lera, Carlos, Polo López, Luz, Gran Ipiña, Ferrán, Albert Brotons, Dimpna C., Abella Antón, Raúl, García Quintana, Antonio, Groba Marco, María del Val, González-Vilchez, Francisco, Almenar-Bonet, Luis, Crespo-Leiro, María G., Gómez-Bueno, Manuel, González-Costello, José, Pérez-Villa, Félix, Delgado-Jiménez, Juan, Arizón del Prado, José María, Sobrino-Márquez, José Manuel, and Sousa Casasnovas, Iago
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- 2020
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7. Análisis de supervivientes a los 8 años del trasplante cardiaco: un estudio caso-control
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Jáuregui-Garrido, Beatriz, Rangel-Sousa, Diego, Sobrino-Márquez, José Manuel, and Lage-Gallé, Ernesto
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- 2017
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8. Novedades en el tratamiento farmacológico de la insuficiencia cardíaca avanzada
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Rangel-Sousa, Diego, Szarvas-Barbella, Joaquín, and Lage-Gallé, Ernesto
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- 2015
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9. Trasplante cardiaco en paciente portador de Berlin Heart EXCOR®, con rechazo agudo refractario a tratamiento corticoideo: un reto diagnóstico
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Pérez-Gómez, Laura, Esteve-Ruiz, Iris María, Campos-Pareja, Ana María, and Rangel-Sousa, Diego
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- 2018
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10. Repetitive ambulatory levosimendan as a bridge to heart transplantation.
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de Juan Bagudá J, de Frutos F, López-Vilella R, Couto Mallón D, Guzman-Bofarull J, Blazquez-Bermejo Z, Cobo-Belaustegui M, Mitroi C, Pastor-Pérez FJ, Moliner-Abós C, Rangel-Sousa D, Díaz-Molina B, Tobar-Ruiz J, Salterain Gonzalez N, García-Pinilla JM, García-Cosío Carmena MD, Crespo-Leiro MG, Dobarro D, Almenar L, Delgado-Jiménez JF, Paredes-Galán E, González-Vílchez F, and González-Costello J
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- Humans, Simendan therapeutic use, Cardiotonic Agents therapeutic use, Retrospective Studies, Treatment Outcome, Hydrazones therapeutic use, Heart Transplantation, Heart Failure drug therapy, Heart Failure surgery, Pyridazines therapeutic use
- Abstract
Introduction and Objectives: Repetitive ambulatory doses of levosimendan are an option as a bridge to heart transplantation (HT), but evidence regarding the safety and efficacy of this treatment is scarce. The objective of the LEVO-T Registry is to describe the profile of patients on the HT list receiving levosimendan, prescription patterns, and clinical outcomes compared with patients not on levosimendan., Methods: We retrospectively reviewed all patients listed for elective HT from 2015 to 2020 from 14 centers in Spain., Results: A total of 1015 consecutive patients were included, of whom 238 patients (23.4%) received levosimendan. Patients treated with levosimendan had more heart failure (HF) admissions in the previous year and a worse clinical profile. The most frequent prescription pattern were fixed doses triggered by the patients' clinical needs. Nonfatal ventricular arrhythmias occurred in 2 patients (0.8%). No differences in HF hospitalizations were found between patients who started levosimendan in the first 30 days after listing and those who did not (33.6% vs 34.5%; P=.848). Among those who did not, 102 patients (32.9%) crossed over to levosimendan after an HF admission. These patients had a rate of 0.57 HF admissions per month before starting levosimendan and 0.21 afterwards. Propensity score matching analysis showed no differences in survival at 1 year after listing between patients receiving levosimendan and those who did not (HR, 1.03; 95%CI, 0.36-2.97; P=.958) or in survival after HT (HR, 0.97; 95%CI, 0.60-1.56; P=.958)., Conclusions: Repetitive levosimendan in an ambulatory setting as a bridge to heart transplantation is commonly used, is safe, and may reduce HF hospitalizations., (Copyright © 2023 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
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11. Use of a surgically implanted, nondischargeable, extracorporeal continuous flow circulatory support system as a bridge to heart transplant.
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Cabezón-Villalba G, Barge-Caballero E, González-Vílchez F, Castel-Lavilla MÁ, Gómez-Bueno M, Almenar-Bonet L, González-Costello J, Lambert-Rodríguez JL, Martínez-Sellés M, de la Fuente-Galán L, Mirabet-Pérez S, García-Cosío Carmena MD, Hervás-Sotomayor D, Rangel-Sousa D, Blasco-Peiró T, Garrido-Bravo IP, Rábago Juan-Aracil G, Muñiz J, and Crespo-Leiro MG
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- Humans, Retrospective Studies, Time Factors, Treatment Outcome, Heart Failure epidemiology, Heart Failure surgery, Heart-Assist Devices adverse effects, Heart Transplantation adverse effects
- Abstract
Introduction and Objectives: We aimed to describe the clinical outcomes of the use of the CentriMag acute circulatory support system as a bridge to emergency heart transplantation (HTx)., Methods: We conducted a descriptive analysis of the clinical outcomes of consecutive HTx candidates included in a multicenter retrospective registry who were treated with the CentriMag device, configured either for left ventricular support (LVS) or biventricular support (BVS). All patients were listed for high-priority HTx. The study assessed the period 2010 to 2020 and involved 16 transplant centers around Spain. We excluded patients treated with isolated right ventricular support or venoarterial extracorporeal membrane oxygenation without LVS. The primary endpoint was 1-year post-HTx survival., Results: The study population comprised 213 emergency HTx candidates bridged on CentriMag LVS and 145 on CentriMag BVS. Overall, 303 (84.6%) patients received a transplant and 53 (14.8%) died without having an organ donor during the index hospitalization. Median time on the device was 15 days, with 66 (18.6%) patients being supported for> 30 days. One-year posttransplant survival was 77.6%. Univariable and multivariable analyses showed no statistically significant differences in pre- or post-HTx survival in patients managed with BVS vs LVS. Patients managed with BVS had higher rates of bleeding, need for transfusion, hemolysis and renal failure than patients managed with LVS, while the latter group showed a higher incidence of ischemic stroke., Conclusions: In a setting of candidate prioritization with short waiting list times, bridging to HTx with the CentriMag system was feasible and resulted in acceptable on-support and posttransplant outcomes., (Copyright © 2023 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
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12. Durable ventricular assist device in Spain (2007-2020). First report of the REGALAD registry.
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Gómez-Bueno M, Pérez de la Sota E, Forteza Gil A, Ortiz-Berbel D, Castrodeza J, García-Cosío Carmena MD, Barge-Caballero E, Rangel Sousa D, Díaz Molina B, Manrique Antón R, Almenar-Bonet L, Uribarri González A, Barrio-Rodríguez A, Castel Lavilla MÁ, López-López L, Dobarro Pérez D, Pastor Pérez F, Burgos-Palacios V, Álvarez-García J, Garrido-Jiménez JM, González-Fernández Ó, Codina P, López-Granados A, Grau-Sepulveda A, and González-Costello J
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- Humans, Spain epidemiology, Treatment Outcome, Registries, Retrospective Studies, Heart-Assist Devices, Heart Failure epidemiology, Heart Failure therapy, Heart Transplantation
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Introduction and Objectives: This report presents the clinical characteristics, outcomes and complications of all consecutive patients implanted with a long-term mechanical circulatory support device in Spain between 2007 and 2020., Methods: Analysis of the Spanish Registry of durable ventricular assist devices (REGALAD) including data form Spanish centers with a mechanical circulatory support program., Results: During the study period, 263 ventricular assist devices were implanted in 22 hospitals. The implanted device was an isolated continuous-flow left ventricular assist device in 182 patients (69%), a pulsatile-flow device (58 isolated left ventricular and 21 biventricular) in 79 (30%), and a total artificial heart in 2 patients (1%). The strategy of the implant was as bridge to heart transplant in 78 patients (30%), bridge to candidacy in 110 (42%), bridge to recovery in 3 (1%) and destination therapy in 72 patients (27%). Overall survival at 6, 12 and 24 months was 79%, 74% and 69%, respectively, and was better in continuous-flow left ventricular assist devices (84%, 80%, and 75%). The main adverse events related to this therapy were infections (37% of patients), bleeding (35%), neurological (29%), and device malfunction (17%)., Conclusions: Durable ventricular assist devices have emerged in Spain in the last few years as a useful therapy for patients with advanced heart failure. As in other international registries, the current trend is to use continuous-flow intracorporeal left ventricular devices, which are associated with better results. Adverse events continue to be frequent and severe., (Copyright © 2022. Published by Elsevier España, S.L.U.)
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- 2023
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13. Infectious complications associated with short-term mechanical circulatory support in urgent heart transplant candidates.
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Solla-Buceta M, González-Vílchez F, Almenar-Bonet L, Lambert-Rodríguez JL, Segovia-Cubero J, González-Costello J, Delgado JF, Pérez-Villa F, Crespo-Leiro MG, Rangel-Sousa D, Martínez-Sellés M, Rábago-Juan-Aracil G, De-la-Fuente-Galán L, Blasco-Peiró T, Hervás-Sotomayor D, Garrido-Bravo IP, Mirabet-Pérez S, Muñiz J, and Barge-Caballero E
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- Humans, Retrospective Studies, Spain epidemiology, Treatment Outcome, Heart Failure epidemiology, Heart Transplantation, Heart-Assist Devices adverse effects
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Introduction and Objectives: Short-term mechanical circulatory support is frequently used as a bridge to heart transplant in Spain. The epidemiology and prognostic impact of infectious complications in these patients are unknown., Methods: Systematic description of the epidemiology of infectious complications and analysis of their prognostic impact in a multicenter, retrospective registry of patients treated with short-term mechanical devices as a bridge to urgent heart transplant from 2010 to 2015 in 16 Spanish hospitals., Results: We studied 249 patients, of which 87 (34.9%) had a total of 102 infections. The most frequent site was the respiratory tract (n=47; 46.1%). Microbiological confirmation was obtained in 78 (76.5%) episodes, with a total of 100 causative agents, showing a predominance of gram-negative bacteria (n=58, 58%). Compared with patients without infection, those with infectious complications showed higher mortality during the support period (25.3% vs 12.3%, P=.009) and a lower probability of receiving a transplant (73.6% vs 85.2%, P=.025). In-hospital posttransplant mortality was similar in the 2 groups (with infection: 28.3%; without infection: 23.4%; P=.471)., Conclusions: Patients supported with temporary devices as a bridge to heart transplant are exposed to a high risk of infectious complications, which are associated with higher mortality during the organ waiting period., (Copyright © 2020 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2022
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14. Spanish Heart Transplant Registry. 31th Official Report of the Heart Failure Association of the Spanish Society of Cardiology.
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González-Vilchez F, Almenar-Bonet L, Crespo-Leiro MG, Gómez-Bueno M, González-Costello J, Pérez-Villa F, Delgado-Jiménez J, Arizón Del Prado JM, Sobrino-Márquez JM, Sousa Casasnovas I, Segovia-Cubero J, Hernández-Pérez F, Martínez Penades S, Cebrián Pinar M, López Vilella R, Sánchez-Lázaro I, Martínez-Dolz L, Paniagua-Martín MJ, Barge-Caballero E, Barge-Caballero G, Couto-Mallón D, López Granados A, Segura Saintgerons C, Menjíbar Pareja V, Carrasco Ávalos F, Cobo M, Llano-Cardenal M, Vázquez de Prada JA, Nistal Herrera F, Blázquez Z, Jesús Valero M, Ortiz C, Zataraín E, Villa A, Navas P, Martínez-Sellés M, Dolores García Cosío M, Morán Fernández L, Caravaca P, Brossa Loidi V, Roig Minguell E, Mirabet Pérez S, López López L, Zegrí I, Rangel Sousa D, Manito Lorite N, Díez Lopez C, Roca Elias J, García Romero E, Rábago Juan-Aracil G, Castel MÁ, Farrero M, Lambert Rodríguez JL, Díaz Molina B, Bernardo Rodríguez MJ, Fidalgo Muñiz C, Camino López M, Gil Jaurena JM, Gil Villanueva N, Garrido-Bravo I, Pascual Figal DA, Pastor Pérez FJ, Blasco-Peiró T, Portoles Ocampo A, Sanz Julve M, de la Fuente Galán L, Tobar Ruiz J, Recio Platero A, García-Guereta Silva L, González Rocafort Á, Labradero de Lera C, Polo López L, Gran Ipiña F, Albert Brotons DC, Abella Antón R, García Quintana A, and Groba Marco MDV
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- Humans, Registries, Societies, Medical, Spain epidemiology, Cardiology, Heart Failure surgery, Heart Transplantation
- Abstract
Introduction and Objectives: The present report describes the clinical characteristics and outcomes of heart transplants in Spain and updates the data to 2019., Methods: We describe the clinical characteristics and outcomes of heart transplants performed in Spain in 2019, as well as trends in this procedure from 2010 to 2018., Results: In 2019, 300 transplants were performed (8794 since 1984; 2745 between 2010 and 2019). Compared with previous years, the most notable findings were the decreasing rate of urgent transplants (38%), and the consolidation of the type of circulatory support prior to transplant, with an almost complete disappearance of counterpulsation balloon (0.7%), stabilization in the use of extracorporeal membrane oxygenation (9.6%), and an increase in the use of ventricular assist devices (29.0%). Survival from 2016 to 2018 was similar to that from 2013 to 2015 (P=.34). Survival in both these periods was better than that from 2010 to 2012 (P=.002 and P=.01, respectively)., Conclusions: Heart transplant activity has remained stable during the last few years, as have outcomes (in terms of survival). There has been a trend to a lower rate of urgent transplants and to a higher use of ventricular assist devices prior to transplant., (Copyright © 2020 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2020
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15. Use of Intra-aortic Balloon Pump as a Bridge to Heart Transplant in Spain: Results From the ASIS-TC Study.
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Barge-Caballero E, González-Vílchez F, Delgado JF, Mirabet-Pérez S, González-Costello J, Pérez-Villa F, Martínez-Sellés M, Segovia-Cubero J, Hervás-Sotomayor D, Blasco-Peiró T, De la Fuente-Galán L, Lambert-Rodríguez JL, Rangel-Sousa D, Almenar-Bonet L, Garrido-Bravo IP, Rábago-Juan-Aracil G, Muñiz J, and Crespo-Leiro MG
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- Female, Follow-Up Studies, Heart Failure mortality, Humans, Male, Middle Aged, Retrospective Studies, Spain epidemiology, Survival Rate trends, Treatment Outcome, Waiting Lists mortality, Heart Failure therapy, Heart Transplantation, Heart-Assist Devices, Intra-Aortic Balloon Pumping instrumentation, Preoperative Care methods, Registries
- Abstract
Introduction and Objectives: In Spain, intra-aortic balloon pump (IABP) has been used frequently as a bridge to urgent heart transplant (HT). We sought to analyze the clinical outcomes of this strategy., Methods: We conducted a case-by-case, retrospective review of clinical records of 281 adult patients listed for urgent HT under IABP support in 16 Spanish institutions from 2010 to 2015. Pre- and post-transplant survival and adverse clinical events were analyzed., Results: A total of 194 (69%, 95%CI, 63.3-74.4) patients were transplanted and 20 (7.1%, 95%CI, 4.4-10.8) died during a mean period of IABP support of 10.9±9.7 days. IABP support was withdrawn before an organ became available in 32 (11.4%) patients. Thirty-five (12.5%, 95%CI, 8.8-16.9) patients transitioned from IABP to full-support mechanical devices. Mean urgent waiting list time increased from 5.9±6.3 days in 2010 to 15±11.7 days in 2015 (P=.001). Post-transplant survival rates at 30-days, 1-year, and 5-years were 88.1% (95%CI, 85.7-90.5), 76% (95%CI, 72.9-79.1), and 67.8% (95%CI, 63.7-71.9), respectively. The incidence rate of major adverse clinical outcomes-device dysfunction, stroke, bleeding or infection-during IABP support was 26 (95%CI, 20.6-32.4) episodes per 1000 patient-days. The incidence rate of IABP explantation due to complications was 7.2 (95%CI, 4.5-10.8) cases per 1000 patient-days., Conclusions: In a setting of short waiting list times, IABP can be used to bridge candidates to urgent HT with acceptable postoperative results, but there were significant rates of adverse clinical events during support., (Copyright © 2018 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2019
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16. Prognostic Value of Serum Lactate Levels in Patients Undergoing Urgent Heart Transplant: A Subanalysis of the ASIS-TC Spanish Multicenter Study.
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Couto-Mallón D, González-Vílchez F, Almenar-Bonet L, Díaz-Molina B, Segovia-Cubero J, González-Costello J, Delgado-Jiménez J, Castel-Lavilla MA, Crespo-Leiro MG, Rangel-Sousa D, Martínez-Sellés M, Rábago-Juan-Aracil G, De-la-Fuente-Galán L, Blasco-Peiró T, Hervás-Sotomayor D, Garrido-Bravo IP, Mirabet-Pérez S, Muñiz J, and Barge-Caballero E
- Subjects
- Biomarkers blood, Female, Follow-Up Studies, Heart Failure blood, Heart Failure mortality, Humans, Male, Middle Aged, Preoperative Period, Retrospective Studies, Spain epidemiology, Survival Rate trends, Treatment Outcome, Emergencies, Heart Failure surgery, Heart Transplantation methods, Lactic Acid blood, Registries, Transplant Recipients statistics & numerical data
- Abstract
Introduction and Objectives: To study the prognostic value of serum lactate in patients under temporary preoperative mechanical circulatory support who underwent urgent heart transplant., Methods: We conducted a subanalysis of a Spanish multicenter registry recording data on patients under temporary mechanical circulatory support listed for highly urgent heart transplant from 2010 to 2015. Participants selected for the present study were those who received a transplant and who had known preoperative serum lactate levels. The main study outcome was 1-year survival after transplant., Results: A total of 177 heart transplant recipients were studied; preoperatively, 90 were supported on venoarterial extracorporeal membrane oxygenation, 51 on temporary left ventricular assist devices, and 36 on temporary biventricular assist devices. Preoperative hyperlactatemia (≥ 2 mmol/L) was present in 44 (25%) patients. On multivariable analysis, pretransplant serum lactate was identified as an independent predictor of 1-year posttransplant survival (adjusted HR per 0.1 mmol/L, 1.02; 95%CI, 1.01-1.03; P = .007). One-year posttransplant survival was 53.1% (95%CI, 45.3-60.9) in patients with preoperative hyperlactatemia and 75.6% (95%CI, 71.8-79.4) in those without preoperative hyperlactatemia (adjusted HR, 1.94; 95%CI, 1.04-3.63; P = .039). Preoperative hyperlactatemia correlated with adverse outcomes in patients supported with extracorporeal membrane oxygenation, but not in patients supported on ventricular assist devices., Conclusions: Preoperative serum lactate is a strong independent predictor of worse outcomes in patients undergoing urgent heart transplant on short-term mechanical circulatory support., (Copyright © 2018 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2019
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17. Real time three-dimensional transesophageal echocardiography in the anatomical assessment of complex mitral valve regurgitation secondary to endocarditis.
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López-Pardo F, González-Calle A, López-Haldón J, Acosta-Martínez J, Rangel-Sousa D, and Rodríguez-Puras MJ
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- Adult, Aged, Coronary Angiography, Echocardiography, Three-Dimensional methods, Endocarditis, Bacterial surgery, Enterococcus faecalis, Female, Humans, Male, Middle Aged, Mitral Valve Insufficiency surgery, Streptococcal Infections complications, Streptococcus mitis, Echocardiography, Transesophageal methods, Endocarditis, Bacterial complications, Mitral Valve Insufficiency diagnostic imaging, Mitral Valve Insufficiency etiology
- Published
- 2012
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