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Introduction: association of breast cancer and pregnancy is not common. The objective of this investigation was to evaluate the pregnancy, young age, stage, treatment, prognosis and mortality of women with breast cancer during pregnancy., Methods: retrospective analysis from March 1992 to February 2009, 16 patients were included with breast cancer and pregnancy. They were analized: histological characteristic of tumor, therapeutic response of the oncological treatment, evolution of the pregnancy. From of baby born: Apgar and weight. The woman's mortality with breast cancer during pregnancy was evaluated for age group and for interval of time between late pregnancy and diagnosis posterior of breast cancer and pregnancy., Results: characteristic predominant clinicohistological: stage III (81.2%), T3-T4 (75%), N+ 93.7%, invasive ductal carcinoma (87.5%), histological grade 2-3 (93.7%), receptor estrogeno positive (43.7%); RPpositive (25%); HER-2/neu positive (31.2%). 27 chemotherapy cycles were applied with 5-fluorouracil, epirubicin and cyclophosphamide during the second or third trimester of the pregnancy, there were not severe adverse effects for the mothers and the baby born exposed to chemotherapy. The mean time to disease recurrence was 18.8 months (range, 6-62 months). The rate of mortality for specific age (< 35 years) was of 31.3% (p = 0.358). From the 16 patients, 7 have died and 9 were live without evidence of disease., Conclusions: the advanced stage and the number of affected axillary lymph node more than the age was predictors of worse pronostic influencing the relapse and mortality of the young patients with breast cancer and pregnancy.

We report the clinical-radiological case of a 25 year-old female patient who developed reversible posterior leukoencephalopathy syndrome (RPLS) in the postpartum period, without evidence of preeclampsia-eclampsia or chronic arterial hypertension. RPLS is associated with diverse clinical entities including eclampsia. Ten days after giving birth, the patient presented with clinical symptoms of headache, elevated blood pressure and seizures. Reversible vasogenic oedema affecting the white matter in the posterior regions was the characteristic finding in magnetic resonance imaging (MRI) of the brain. Although the prognosis is favourable, treatment needs to be early and aggressive, with rapid control of the convulsions and arterial hypertension, with the aim of preventing ischemia and cerebral infarct from developing. There is a need to be highly alert and to consider the diagnosis of RPLS in women presenting with convulsions and other neurological symptoms in postpartum.

Epithelioid hemangioendothelioma is an infrequent mesenchymal tumor of unknown etiology and variable clinical symptoms. It usually affects black, middle-aged women. The most frequent symptoms are right hypochondrium pain, abdominal discomfort and constitutional syndrome with progressive liver damage. Diagnosis is difficult and detailed pathological analysis is required. Controlled clinical studies are lacking and there are no factors that predict the clinical course or serve as a guide to the most effective treatment. We report 3 cases with distinct clinical course ranging from clinical stability to dissemination and death. Treatment differed in the three patients.

The spontaneous hepatic rupture during pregnancy or puerperium has been reported as a rare complication, with an extraordinary severity. Usually it's a pregnancy hypertensive disease complication. Since 1990 it had been reported 120 cases from this pathology in the world literature. We reported a case from a patient who presented spontaneous hepatic rupture during the immediately puerperium and a world literature revision.

The 23 year experience in the Laboratory of Cytology of the Catholic University with the Papanicolaou (PAP) test in pregnant and puerperal women was analyzed. Six hundred eighty eight cases (1,9%) with abnormal smears were collected from a total of 36,524 women. A cytological diagnosis of invasive carcinoma was made in 8 cases, of high-grade intraepithelial neoplasia in 130 cases, of low-grade intraepithelial neoplasia in 292 cases, and a "non conclusive" diagnosis was made in 258 cases. In 6 out of the 8 cases with a cytological diagnosis of invasive carcinoma, this diagnosis was confirmed by histology, and in two other cases the histology showed an in situ carcinoma. Histology was negative in only 3 cases with cytological diagnosis of high-grade intraepithelial neoplasia. The PAP test is also highly effective during pregnancy and puerperium, and its rate of false negative cases is low. We suggest to take advantage of the opportunity the prenatal control offers for taking a PAP test.

Two cases of mesenteric venous thrombosis (MVT) during puerperium are reported and the medical literature about this condition is reviewed. In none of the 65 articles reviewed was an association of these conditions reported. We believe that there are certain hematologic and hormonal conditions in puerperium that may explain this association. The current clinical presentation, diagnostic modalities and management are presented, and we think that it should be suspected in a patient in puerperium with symptoms of acute abdomen.