6 results on '"Martín-Olmedo P"'
Search Results
2. Disruptores endocrinos. El caso particular de los xenobióticos estrogénicos. II Estrógenos sintéticos
- Author
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Olea Serrano, N., Fernández Cabrera, M. F., and Martín Olmedo, P.
- Subjects
plaguicidas ,dioxines ,phthalates ,dioxines, phthalates ,xenoestrogens ,dioxinas ,xenoestrógenos ,disruptores endocrinos ,pesticides ,bifenilos policlorados ,endocrine disruptors ,bisphenols ,alkylphenols ,ftalatos ,Medicine ,PCBs ,alquilfenoles ,bisfenoles - Abstract
In recent years, it has been demonstrated that endocrine systems of living beings can be altered by many chemical substances of anthropogenic origin, designated as endocrine disrupters. There are growing concerns about the number of these endocrine disrupters. It has not been possible to define a single chemical structure that allows the classification of a chemical compound as a mimic of female sex hormones, so that chemical structures similar to natural estrogens, based on cyclopentanoperhydrophenanthrene, share their hormonal effect with stilbenes, bisphenols, alkylphenols, dioxins, furans and parabenes. The recognition of estrogenic activity in different biological models has been used to update the list of xenoestrogens and reveal sources of human exposure that were previously unknown. New previously unsuspected chemical compounds have been added to the list, as well as their precursors, metabolites and degradation products, whose effects are only now beginning to be recognised. En los últimos años se ha puesto en evidencia que muchas sustancias químicas de origen antropogénico son capaces de alterar el sistema endocrino de los seres vivos y se ha acuñado el nombre de disruptores endocrinos para definirlas. El número de disruptores endocrinos es una preocupación creciente si se añade a la inclusión de nuevos compuestos químicos, hasta ahora insospechados, la información generada sobre sus precursores, metabolitos y productos de degradación que tan solo ahora empiezan a conocerse. No se ha podido definir una estructura química única que permita clasificar a un compuesto químico como mimetizador de las hormonas sexuales femeninas, de tal manera que estructuras químicas similares a los estrógenos naturales, basados en el ciclopentanoperhidrofenantreno, comparten con los estilbenos, bisfenoles, bifenilos, alquilfenoles, dioxinas, furanos y parabenes su efecto hormonal estrogénico. El reconocimiento de la actividad estrogénica en diferentes modelos biológicos se ha utilizado para actualizar el censo de xenoestrógenos y poner de manifiesto fuentes de exposición humana hasta el momento insospechadas.
- Published
- 2001
3. [Health impact assessment of the San Fernando street renewal project in Alcalá de Guadaíra (Seville, Spain)].
- Author
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Venegas-Sánchez J, Rivadeneyra-Sicilia A, Bolívar-Muñoz J, López-Fernández LA, Martín-Olmedo P, Fernández-Ajuria A, Daponte-Codina A, Ruiz-Fernández J, and Artundo-Purroy C
- Subjects
- Adolescent, Adult, Aged, Environmental Health, Female, Health Plan Implementation, Health Policy, Humans, Male, Middle Aged, Pregnancy, Program Evaluation, Prospective Studies, Public Policy, Quality of Life, Social Determinants of Health, Social Problems, Socioeconomic Factors, Spain, Urban Renewal methods, Urban Renewal statistics & numerical data, Vulnerable Populations, Young Adult, Health Impact Assessment, Residence Characteristics, Urban Health, Urban Renewal organization & administration
- Abstract
Objectives: This study describes the design and implementation of a health impact assessment (HIA) conducted in 2010 of the regeneration project of San Fernando Street, the main avenue crossing the San Miguel-El Castillo neighborhood in Alcala de Guadaíra (Seville, Spain). This project is part of the wider URBAN Plan aimed at the social, urban and economic regeneration of the city's historic center., Methods: This experience followed the standard HIA stages and procedures. The review of published evidence was complemented with new qualitative information gathered by means of a participative workshop with the local population and interviews with social and health workers involved in the neighborhood., Results: During the building stage of the project, the adverse impacts were related to a worsening of the air quality, increased noise pollution, mobility restrictions and a higher risk of accidents, particularly among older or disabled people. Once the building stage was finished, the health benefits were associated with significant improvements in physical accessibility and the population's access to health services and other goods and services. Other positive effects were the enhanced safety and attractiveness of the neighborhood and the new opportunities for socializing, social cohesion and increasing the community's self-esteem., Conclusions: This is the first HIA experience in Andalusia whose results have been integrated into a formal cycle of decision making in the local community. This experience has provided new evidence of the potential of HIA and its applicability and acceptance at the municipal level and has has also facilitated a learning process and the piloting of new methods and tools associated with the HIA process., (Copyright © 2012 SESPAS. Published by Elsevier Espana. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
4. [Studies conducted in Spain on concentrations in humans of persistent toxic compounds].
- Author
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Porta M, Puigdomènech E, Ballester F, Selva J, Ribas-Fitó N, Domínguez-Boada L, Martín-Olmedo P, Olea N, Llop S, and Fernández M
- Subjects
- Humans, Spain, Hazardous Substances analysis
- Abstract
No systematic review is available on studies conducted in Spain on human concentrations of persistent toxic substances (PTS). The objectives were: to identify studies conducted in Spain in the past 30 years that determined concentrations in humans of dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethane (DDE), hexachlorobenzene (HCB), hexachlorocyclohexane (HCH) and polychlorinated biphenyls (PCBs); and to summarize the main characteristics and results of each study. Studies are highly heterogeneous and most lack population representativeness. Concentrations of DDT and DDE might have decreased moderately in the last 20 years. Numerous fluctuations are apparent in levels of HCB, HCHs and PCBs, in some instances compatible with some stagnation. There are enormous differences in levels detected across and within studies: PTS concentrations of some individuals may be over 200-fold higher than those of others. The actual magnitude of human contamination by PTS and their trends across Spain -as well as the geographic and social heterogeneity- remain largely unknown.
- Published
- 2008
- Full Text
- View/download PDF
5. [Comparison of two models of education for asthmatic patients].
- Author
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Martín Olmedo P, León Jiménez A, Benítez Rodrígueza E, Gómez Gutiérrez JM, and Mangas Rojas A
- Subjects
- Adolescent, Adult, Aged, Humans, Middle Aged, Models, Educational, Prospective Studies, Asthma therapy, Patient Education as Topic methods
- Abstract
Background: The education programs have demonstrated to be an important point in the management of asthmatic patients. The aim of the present study was to assess if an intensive group asthma education program was able to improve a simplified and individual asthma education program, both with a self-management plan included., Patients and Method: A prospective randomised controlled trial was conducted over 12 months and 73 moderate-severe asthmatic patients were included. Patients were randomly assigned to control or study group. Patients in control group received individual and simplified education with a self-management plan and patients in study group attended an <
> in small groups where they received a three hours education program in three weeks.The outcome measures were: number of hospital admissions, observation unit admissions, emergency visits and unscheduled general practice consultations. Knowledge, adherence to treatment, ability with inhaler devices, airway function, environmental control measures and quality of life. They were assessed at the beginning and the end of the study., Results: At the end of the study period the outcome of morbidity had improved in both groups but the number of observation unit admissions (p = 0.028) and unscheduled general practice consultations (p = 0.022) was substantially lower in study group. This group also demonstrated improvement in environmental control measures and better inhaler technique and knowledge (p = 0.007). In adherence, lung function or quality of life there were no differences between groups., Conclusions: In patients with asthma better results can be obtained with an intensive group asthma education program than with the individual and simplified program. - Published
- 2001
- Full Text
- View/download PDF
6. [Evaluation of theory-practice knowledge on inhalation systems in primary care physicians, post-graduates in training and undergraduates].
- Author
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Madueño Caro AJ, Martín Olmedo PJ, García Martí E, and Benítez Rodríguez E
- Subjects
- Adult, Education, Medical, Undergraduate, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Asthma drug therapy, Education, Medical, Graduate, Educational Measurement, Nebulizers and Vaporizers, Primary Health Care
- Abstract
Objective: To find the theoretical and practical knowledge concerning inhalation systems of primary care doctors, postgraduates in training--family & community medicine (FCM) residents--and undergraduates who had passed their course in pneumology., Design: Crossover, descriptive study., Setting: FCM teaching unit of the Puerta del Mar Hospital (Cadiz), the Cadiz Faculty of Medicine and seven primary care centres on the Bay of Cadiz., Participants: 31 practising primary care doctors, 25 third-year FCM residents and 31 medical students were evaluated., Measurements and Main Results: A thirteen-point questionnaire was used to evaluate the subjects theoretical knowledge of inhalation systems. The percentage of correct replies was used to establish reply levels. Their techniques of handling different systems of inhalation (pressurised cartridge, pressurised cartridge with spacing chamber, Turbuhaler and Accuhaler) were assessed according to the guidelines of the SEPAR (Spanish Society of Pneumology and Thoracic Surgery). 26% of the practising doctors and residents answered over 75% of the questionnaire correctly, with no significant differences between the two groups (p > 0.66). No undergraduate reached 75% of correct answers. After exclusion of asthmatic participants, three of the practising doctors (9.7%) and one of the residents (4.8%) performed the technique correctly with the four systems: there were no differences between the two groups (p > 0.87). No undergraduate performed them satisfactorily., Conclusions: Specific training for primary care doctors in handling inhalation therapy is recommended.
- Published
- 2000
- Full Text
- View/download PDF
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