1. [Infective endocarditis by Abiotrophia defectiva diagnosed by mass spectrometry (MALDI-TOF MS) in Argentina].
- Author
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Lipari F, Martínez M, Hernández D, Laborie M, and Caeiro JP
- Subjects
- Anti-Bacterial Agents therapeutic use, Endocarditis, Bacterial drug therapy, Female, Gram-Positive Bacterial Infections drug therapy, Humans, Middle Aged, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Vancomycin therapeutic use, Abiotrophia isolation & purification, Endocarditis, Bacterial diagnostic imaging, Gram-Positive Bacterial Infections diagnostic imaging
- Abstract
We report the case of a 63-year-old woman with congestive heart failure due to a bicuspid aortic valve and severe aortic stenosis. The patient had a febrile syndrome with positive blood cultures for Abiotrophia defectiva, Transesophageal echocardiogram revealed the presence of paravalvular abscess, which was treated by a successful valve replacement. The patient received appropriate antibiotic therapy with intravenous vancomycin, leading to a successful response. The use of MALDI-TOF MS as a rapid and specific method for the microbiological diagnosis is discussed in the following report.
- Published
- 2016
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