1. Mycoplasma genitalium in Spain: prevalence of genital infection and frequency of resistance to macrolides.
- Author
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Asenjo A, Kusters JG, Severs TT, and Alós JI
- Subjects
- Adult, Anti-Bacterial Agents therapeutic use, Drug Resistance, Bacterial, Female, Genital Diseases, Female drug therapy, Genital Diseases, Male drug therapy, Humans, Macrolides therapeutic use, Male, Mycoplasma Infections drug therapy, Prevalence, Young Adult, Anti-Bacterial Agents pharmacology, Genital Diseases, Female epidemiology, Genital Diseases, Female microbiology, Genital Diseases, Male epidemiology, Genital Diseases, Male microbiology, Macrolides pharmacology, Mycoplasma Infections epidemiology, Mycoplasma Infections microbiology, Mycoplasma genitalium drug effects
- Abstract
Introduction: The aim of this study was to determine the prevalence of Mycoplasma genitalium infection and the resistance to macrolides within a general population in Madrid in 2015., Methods: We collected 359 urine samples from a general population with symptoms of sexually transmitted infections (STIs). All samples underwent a real-time PCR. For the detection of macrolide resistance, a 283bp fragment of region V of the 23S rRNA gene of M. genitalium was amplified and sequenced., Results: We found a prevalence of 3.34% of M. genitalium and a macrolide resistance rate of 20%. In males, the prevalence was 6.62% and in women 0.96%, being significantly higher in males., Conclusions: The prevalence obtained shows that it is a pathogen to consider in our environment. These findings stress the need for routine testing of M. genitalium infections and would seem to suggest the advisability of resistance testing., (Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.)
- Published
- 2018
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