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Unlabelled: The heart has rarely been studied in patients infected with HIV. Diastolic dysfunction is the most frequently observed alteration , which could be due to direct viral action on the myocardium or due to autoimmune mechanism or concomitant infections by cardiotropic virus. The Doppler tissue is a more effective tool than the trans-mitral one to evaluate the diastolic function since is not influenced by preload, afterload or heart rate., Objectives: To study the prevalence of the left ventricular diastolic dysfunction (DDVI) in the HIV (+) group of patients, without symptoms or diagnosis of heart-disease and to analyze their relationship with the CD4 levels and the viral charge., Material and Methods: We prospectively studied 50 HIV(+) patients with no symptoms of cardiac involvement who underwent an echocardiogram using Doppler tissue compared with 50 healthy persons matched sex and age as control group., Results: The infection of HIV was associated with DDVI and with CD4 Lymphocytes levels (p<0,05). The association between DDVI and viral load was not found., Conclusions: There is an association between the HIV infection and the presence of DDVI in asymptomatic patients. The long term monitoring studies should be considered in HIV (+) patients with silent diastolic dysfunction to evaluate their possible progression to the systolic dysfunction.

Introduction: Insomnia is a sleep disorder characterized by a deficient or poor quality sleep, with adverse daytime consequences. Prevalence is 30-50% in adults and can be associated with depression or lead to the development of this condition. Despite the high prevalence rates, is a unrecognized, misdiagnosis and undertreated. There is not much publications about its prevalence in patients with chronic diseases., Objectives: to determine prevalence and clinical characteristics of insomnia in outpatients with chronic diseases., Materials and Methods: Prospective observational cross-sectional descriptive study. Insomnia was defined based on ICSD-2criteria. The data collection was performed by a questionnaire., Results: We surveyed 100 patients who attended the consultation of various clinical specialties, mean age 50 years old, 57% were women. Sixty nine per cent of them met criteria for insomnia. The most prevalent diseases were hypertension: 57%, asthma 20%, diabetes: 18% and hypothyroidism: 17%. Among patients with insomnia, 62% were women, 35% had insomnia without another illness, and the remaining 65% had secondary conditions associated with insomnia (60% depression). 25% of patients consulting for insomnia ever. The prevalence of criteria for depression in outpatients with chronic diseases was 52%, amounting to 63% in patients suffering from insomnia., Discussion: The prevalence of insomnia in patients with chronic diseases is high (in outpatients with chronic disease: 69%), higher than the average rate described in the general population. It is an undertreated condition., Conclusions: The prevalence of insomnia in patients with chronic diseases is high, it is underdiagnosed and undertreated. It is associated with depression in high rate.