32 results on '"Celis J"'
Search Results
2. Efecto de la aplicación de fibra de coco (Cocos nucifera L.) en el almacenamiento y eficiencia del uso del agua en un Alfisol, sembrado con ballica (Lolium multiflorum L.) y en la toxicidad en lechuga (Lactuca sativa L.)
- Author
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Sandoval, M., Zapata, M., Celis, J., Quezada, C., Capulín, J., and Solís, A.
- Abstract
The search for techniques that allow a more efficient use of water is a global task, since this resource is increasingly scarce and its quality is constantly deteriorating. The objective of this study was to determine the effect of applying coconut fiber CF on physical-hydric parameters of the soil and its water use efficiency (WUE). The effects of coconut fiber (CF) were assessed on water consumption, water use efficiency and aerial and root biomass of Italian ryegrass (Lolium multiflorumL.). In addition, it was also evaluated whether CF causes toxic effects on lettuce seeds (Lactuca sativaL.). Treatments were established according to the proportion of CF and soil in g g-1soil CF: T1 = 1:80, T2 = 1:40 and T3 = 1:20, and a control treatment (T0 = no substrate). Additionally, 3 charges of water (100, 75, 50 % of field capacity) were established. Results showed that the best treatment for water consumption was T3-50 (377.8 ml), for WUE the best treatment was T3-100 (8.52 kg DM m-3), for aerial biomass it was T3-100 (4.59 g MS) and in the case of root biomass the best treatment was T3-100 (1.92 g MS). It was concluded that the addition of coconut fiber substrate to the mix improves the physical and hydrological characteristics of degraded soil. There were no toxic effects on lettuce among the applied rates of CF. The germination index (IG) ranged from 124.82 to 156.03 % and the best treatments were T3 and T2.  , La búsqueda de alternativas que permitan un uso más eficiente del agua es una tarea mundial, puesto que este recurso es cada vez más escaso y su calidad se deteriora. De ahí que la presente investigación tuvo como objetivo determinar el efecto de la aplicación de fibra de coco (FC) sobre parámetros físico-hídricos del suelo y su eficiencia en el uso del agua (EUA). Se probaron los efectos de la FC sobre el gasto de agua, sobre la EUA, biomasa aérea y radical en ballica italiana (Lolium multiflorumL.). Además se evaluó si la FC presenta efectos tóxicos sobre las semillas de lechuga (Lactuca sativaL.). Los tratamientos fueron establecidos de acuerdo a la proporción de FC y suelo, en gramos FC g-1suelo: T1 = 1:80, T2 = 1:40 y T3 = 1:20, y un testigo (T0 = Sin sustrato). Adicionalmente, se establecieron 3 cargas de agua (100, 75, 50 % de capacidad de campo). Los resultados muestran que el menor consumo de agua se dio en el tratamiento T3-50 (377,8 ml), para la EUA el mejor tratamiento fue T3-100 (8,52 kg MS m-3), para biomasa aérea, el mejor fue el tratamiento T3-100 (4,59 g MS) y en el caso de la biomasa radical su mejor tratamiento fue el T3-100 (1,92 g MS). Por lo tanto, al adicionar el sustrato de fibra de coco en la mezcla, este permite un mejoramiento en las características físico-hídricas del suelo degradado. Las pruebas con lechuga indicaron que no existen efectos tóxicos entre las dosis aplicadas de FC. Los índices de germinación (IG) variaron entre 124,82 a 156,03 % y los mejores tratamientos fueron para T3 y T2.  
- Published
- 2013
3. Gallstone disease post-radical gastrectomy for gastric adenocarcinoma at the national institute of neoplastic diseases: january 1990 to december 2000
- Author
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Torres Solis, José, Celis, J., Ruiz, E., Payet, E., Chavez, I., Berrospi, F., Young, F., and Luque, C.
- Subjects
Gastrectomía total y subtotal distal ,Subtotal gastrectomy ,Gastric adenocarcinoma ,gallbladder stones ,total gastrectomy ,Adenocarcinoma Gástrico ,Litiasis Vesicular ,Adenocarcinoma Gástrico, Gastrectomía total y subtotal distal, Litiasis Vesicular - Abstract
OBJETIVO: Determinar la frecuencia de litiasis vesicular en pacientes post-operados con gastrectomía por adenocarcinoma gástrico, determinar el tiempo de aparición de litiasis vesicular en pacientes gastrectomizados por Adenocarcinoma Gástrico. MÉTODOS: Se realizo un estudio observacional, descriptivo retrospectivo. Se revisó un total de 148 historias clínicas de pacientes sometidos a gastrectomía por adenocarcinoma gástrico en el Instituto Nacional de Enfermedades Neoplásicas en el periodo de 1990 al 2000. RESULTADOS: De los 148 casos de pacientes post gastrectomizados por adenocarcinoma gástrico que fueron enrolados, 29(19.6%) presentaron litiasis vesicular versus 119(80.9%) que no presentaron litiasis vesicular como complicación post gastrectomía. La media de edad de 29 pacientes con litiasis vesicular post gastrectomía por adenocarcinoma gástrico fue de 59.9años (min. 39años máx.74años). La distribución de la litiasis vesicular en relación al sexo fue, femenino 18(62.1%) casos y masculino 11(37.9%) casos. La media del tiempo de aparición de la litiasis vesicular post gastrectomía fue de 3.1 años, para el sexo masculino 2.7años y para el sexo femenino de 3.3 años .Según el tipo de cirugía se presento litiasis vesicular en 14 pacientes que fueron sometidos a Gastrectomía Subtotal Distal y a 15 pacientes a los que se les practicó Gastrectomía Total. CONCLUSIONES: la Frecuencia de litiasis vesicular post gastrectomía fue de 19.6% . El periodo de aparición de colelitiasis fue de 3.1 años. La colecistectomía podría ser una toma de decisión importante en pacientes con alto riesgo de litiasis y cáncer vesicular post gastrectomía. El presente trabajo de investigación invita a realizar otros estudios de tipo cohorte en el cual se determine el factor de riesgo principal para la aparición de esta complicación. SUBJECT: To determinate the frecuency and the time of development of the gallbladder stones in gastrectomy post-operated patients with stomach adenocarcinoma at The National Cancer Institute in Lima, Peru. METHODS: In an observational, descriptive and retrospective case series design, 148 patiens' files who underwent gastrectomy for stomach adenocarcinoma in the National Cancer Institue of Lima during 1990 and 2000, have been reviewed looking for the development. RESULTS: A total de 148 patients were involved in this study. 29 of them (19.6%) develop gallbladder stones during the (x years of) follow up vs 119 (80.9%). The mean age ot the 29 patients with gallbladder stones were 59.9 years ans 18 of them were female and 11 male.\The mean time of develop gallbladder stones was 3.1 years. According to the type of surgery, 14 patient wiht gallbladder stones underwent to subtotal gastrectomy and 15 to total gastrectomy. CONCLUSIONS The frecuency of gallbladder stones post gastrectomy in this study was 19.6%. The mean time of the develop and diagnosis of litiasis was 3.1 years. To perform the colecistectomy at the same time of the gastrectomy could be an important decision in patients with high risk of gallstones and gallbladder cancer. We need furthermore studies to have conclusions about the risk factors.
- Published
- 2011
4. Actividad respiratoria de microorganismos en un suelo patagónico enmendado con lodos salmonícolas
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Celis, J, Sandoval, M, and Zagal, E
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residuos orgánicos ,eutrophication ,sedimentos ,aquaculture ,acuicultura ,sediments ,organic wastes ,eutroficación - Abstract
Pollution of aquatic fresh water and soil is of great concern in the salmon farming industry. Water is the most important vehicle for the transmission of organic polluting agents, and for that reason the sediments (sludge) near to salmon facilities could become enriched reservoirs of pathogens and chemicals. A solution to this problem could be to incorporate the sludge into the soil under sustainable procedures. In order to investigate the addition of salmon sludge to soils, sediment samples from a pisciculture and a lake were applied to a degraded in the soil southern Chilean Patagonia. Microbial biological activity was evaluated under different salmon sludge addition rates: 25, 50, 75, 100 y 150 t ha-1by using respirometry tests (C-CO2) in samples under closed incubation in laboratory. The results showed that microorganisms increased their respiratory activity along with time and increased sludge concentrations, indicating the amount of sludge that is possible to incorporate into a soil without causing adverse environmental effects.  , La contaminación de los suelos y de los ecosistemas acuáticos de agua dulce es una preocupación constante para la industria de la salmonicultura. El agua es el vehículo más importante para la transmisión de contaminantes orgánicos, y por ello los sedimentos (lodos) próximos a las instalaciones de una piscicultura o salmonicultura pueden convertirse en reservorios de patógenos y químicos. Una solución es enmendar estos lodos en suelos de manera sustentable. Para investigar la adición de lodos residuales de salmonicultura en suelos, muestras de sedimentos obtenidos de piscicultura y de lago fueron aplicadas a un suelo patagónico degradado del sur de Chile. Se evaluó la actividad biológica de los microorganismos bajo diferentes dosis de lodos enmendados al suelo: 25, 50, 75, 100 y 150 t ha–1. La determinación se realizó mediante pruebas de respirometría (C-CO2) en muestras sometidas a incubación cerrada en laboratorio por60 días. Los resultados mostraron que los microorganismos aumentan su actividad respiratoria a medida que transcurre el tiempo y con mayores tasas de aplicación de lodo, indicando con ello la cantidad de lodo residual que es posible disponer o verter en un suelo sin provocar efectos ambientales adversos.  
- Published
- 2009
5. [Microbiological study of infectious endophthalmitis with positive culture within a 13 year-period].
- Author
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Asencio MA, Huertas M, Carranza R, Tenías JM, Celis J, and González-Del Valle F
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- Adolescent, Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents pharmacology, Anti-Bacterial Agents therapeutic use, Anti-Infective Agents pharmacology, Antifungal Agents pharmacology, Antifungal Agents therapeutic use, Child, Child, Preschool, Female, Gram-Negative Bacterial Infections drug therapy, Gram-Negative Bacterial Infections microbiology, Gram-Positive Bacterial Infections drug therapy, Gram-Positive Bacterial Infections microbiology, Humans, Infant, Male, Microbial Sensitivity Tests, Middle Aged, Mycoses drug therapy, Mycoses microbiology, Retrospective Studies, Staphylococcus epidermidis drug effects, Young Adult, Anti-Infective Agents therapeutic use, Endophthalmitis drug therapy, Endophthalmitis microbiology
- Abstract
Introduction: Our objectives are to describe the microbial spectrum and antimicrobial susceptibility of isolates from patients with culture-proven endophthalmitis., Material and Methods: Retrospective study of patients with microbiological diagnosis of endophthalmitis treated at the Ophthalmology Department of the General Hospital La Mancha Centro in the period 1996-2008. The identification of isolates was performed using the automated VITEK-2® and Api galleries (bioMérieux, Spain SA). The antimicrobial susceptibility was performed by the VITEK-2® system (bioMérieux, Spain SA), E-test strips (MIC Test Strip, Liofilchem, Italy) and Sensititre® YeastOne trading system (Trek Diagnostic Systems, Ohio, USA) for Candida species., Results: Forty four (70%) of 63 cases of endophthalmitis were culture positive. Gram-positive bacteria were much more common than gram-negative bacteria in both postoperative endophthalmitis (POE) and post-traumatic endophthalmitis (PTE). Staphylococcus epidermidis was predominant in POE, while Bacillus sp. predominated in the PTE; furthermore, the 75% of total fungal isolates corresponded to postraumatic cases. The isolated strains showed 100% susceptibility to vancomycin, ceftazidime and amikacin, while resistance to ciprofloxacin was greater than 15%. The empirical antifungal therapy failed in 50% of cases. The visual prognosis was significantly less favorable in the PTE., Conclusions: Based on the susceptibility of our isolates, vancomycin, ceftazidime and amikacin are good choices for empirical treatment of endophthalmitis, unlike ciprofloxacin. We recommend conducting antifungal prophylaxis after penetrating ocular trauma in a rural environment.
- Published
- 2014
6. [Intracameral fibrin glue in spontaneous corneal perforation].
- Author
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Celis J, Mesa D, Avendaño E, and González-Valle F
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- Aged, Humans, Injections, Intralesional, Male, Corneal Perforation therapy, Fibrin Tissue Adhesive administration & dosage, Tissue Adhesives administration & dosage
- Abstract
Case Report: A 70-year-old male was referred to our department due to a herpetic corneal perforation in the left eye. The perforation was healed with intracameral fibrin tissue sealant (Tissucol(®)), an amniotic membrane, and a large diameter soft contact lens. Postoperatively there were complete dissolution of the fibrin sealant and closure of the perforation without endothelial damage., Discussion: Intracameral fibrin glue may be effective in the closure of corneal perforations., (Copyright © 2011 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.)
- Published
- 2014
- Full Text
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7. [Impact of splenectomy and/or distal pancreatectomy in the prognosis of the proximal gastric cancer].
- Author
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Mori Gonzales E, Celis J, Ruiz E, Payet E, Berrospi F, Chavez I, Young F, Luque C, and Montes J
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- Adenocarcinoma mortality, Adenocarcinoma pathology, Adult, Aged, Aged, 80 and over, Female, Follow-Up Studies, Humans, Lymph Node Excision, Lymphatic Metastasis, Male, Middle Aged, Postoperative Complications epidemiology, Prognosis, Retrospective Studies, Stomach Neoplasms mortality, Stomach Neoplasms pathology, Survival Analysis, Adenocarcinoma surgery, Gastrectomy, Pancreatectomy, Splenectomy, Stomach Neoplasms surgery
- Abstract
Objectives: Identify prognostic factors associated to total or proximal gastrectomy with or without splenectomy and / or distal pancreatectomy in patient with proximal gastric cancer. Evaluate the frequency of lymph node metastasis to the hilum and splenic artery, postoperative morbidity and mortality and the impact of lymphadenectomy of group 10 and 11 on long term survival., Materials and Methods: We performed an observational, descriptive, longitudinal and retrospective study analyzing patients with diagnostic of proximal third gastric adenocarcinoma subjected to total or proximal gastrectomy with or without splenectomy or distal pancreatectomy in the service of Abdomen of the Instituto Nacional de Enfermedades Neoplásicas between 1990 and 2005. Overall survival for each of the groups was calculated using the Kaplan-Meier method, prognostic factors were evaluated using univariate and multivariate analysis., Results: We studied 219 patients with proximal third gastric adenocarcinoma (cardias and bottom), of wich, according to inclusion criteria, only qualify 129 (N=129): 22 (17.1%) were treated by gastrectomy alone, 79 (61.2%) gastrectomy associated witch splenectomy and 28 (21.7%) gastrectomy with distal pancreatosplenectomy, constituting three treatment groups. We compared the survival of each group and each factor analyzed, determining the following prognostic factors: lymph node metastasis (N2-N3), degree of differentiation, undifferentiated tumors and Borrmann III and IV tumors. Neither splenectomy or distal pancreatectosplenectomy improved survival compared to the gastrectomy alone. The morbidity and mortality was higher in patients with more aggressive but more aggressive surgery without significant value., Conclusions: The number of nodes removed in patients who had pancreatosplenectomy and /or splenectomy was higher, however, had no impact on survival at 5 years.
- Published
- 2012
8. [Gallstone disease post-radical gastrectomy for gastric adenocarcinoma at the National Institute of Neoplastic Diseases, January 1990 to December 2000].
- Author
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Torres Solis J, Celis J, Ruiz E, Payet E, Chavez I, Berrospi F, Young F, and Luque C
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- Adenocarcinoma epidemiology, Adult, Aged, Cancer Care Facilities statistics & numerical data, Cholecystectomy, Cholelithiasis etiology, Cholelithiasis prevention & control, Female, Humans, Incidence, Male, Middle Aged, Peru, Postgastrectomy Syndromes etiology, Postgastrectomy Syndromes prevention & control, Retrospective Studies, Stomach Neoplasms epidemiology, Adenocarcinoma surgery, Cholelithiasis epidemiology, Gastrectomy methods, Postgastrectomy Syndromes epidemiology, Stomach Neoplasms surgery
- Abstract
Subject: To determinate the frecuency and the time of development of the gallbladder stones in gastrectomy post-operated patients with stomach adenocarcinoma at The National Cancer Institute in Lima, Peru., Methods: In an observational, descriptive and retrospective case series design, 148 patiens' files who underwent gastrectomy for stomach adenocarcinoma in the National Cancer Institue of Lima during 1990 and 2000, have been reviewed looking for the development of gallbladder stones., Results: A total de 148 patients were involved in this study. 29 of them (19.6%) develop gallbladder stones during the (x years of) follow up vs 119 (80.9%) . The mean age ot the 29 patients with gallbladder stones were 59.9 years ans 18 of them were female and 11 male.\The mean time of develop gallbladder stones was 3.1 years.According to the type of surgery, 14 patient wiht gallbladder stones underwent to subtotal gastrectomy and 15 to total gastrectomy., Conclusions: The frecuency of gallbladder stones post gastrectomy in this study was 19.6%. The mean time of the develop and diagnosis of litiasis was 3.1 years.To perform the colecistectomy at the same time of the gastrectomy could be an important decision in patients with high risk of gallstones and gallbladder cancer.We need furthermore studies to have conclusions about the risk factors.
- Published
- 2011
9. [Surgical outcome of 801 patients with localized gastric cancer treated with d2 lymphadenectomy].
- Author
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Ruiz E, Sanchez J, Celis J, Payet E, Berrospi F, Chavez I, and Young F
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- Adult, Aged, Aged, 80 and over, Cancer Care Facilities statistics & numerical data, Female, Follow-Up Studies, Gastrectomy methods, Hospital Mortality, Humans, Kaplan-Meier Estimate, Lymph Node Excision methods, Male, Middle Aged, Neoplasm Staging statistics & numerical data, Pancreas pathology, Pancreatectomy, Peru epidemiology, Prospective Studies, Stomach Neoplasms mortality, Treatment Outcome, Gastrectomy statistics & numerical data, Lymph Node Excision statistics & numerical data, Stomach Neoplasms surgery
- Abstract
Background: D2 gastrectomy has been regarded as an inconvenient procedure with high morbidity and no survival benefit in the West. Recent studies, however, have shown low mortality and a survival benefit of D2 gastrectomy. In the Instituto de Enfermedades Neoplasicas (INEN) of Lima Peru D2 gastrectomy is performed since 1990 after training of some of the authors in the NCC of Tokyo Japan. Distal Pancreatectomy was performed only if the pancreas was involved.The aim of this study was to evaluate the peri operative mortality and survival in a group of patients who had a standard D2 lymphadenectomy according to the rules of the Japanese Research Society for Gastric Cancer. Data were collected prospectively, and patients were followed for more than 7 years., Methods: Between 1990 and 1999, 938 patients with localized gastric cancer were registered at INEN. Of these, 801 patients underwent curative resection with extended lymphadenectomy (D2). Postoperative morbidity/mortality, type of gastrectomy, mean of lymph nodes removed, pTNM stages and Survival Time and were analyzed., Results: Sub total distal gastrectomy was performed in 511 patients and total gastrectomy in 290 patients. The mean number of lymph nodes removed was 46.48 per patient (54.91 nodes for total and 41.69 for sub total distal gastrectomy). Hospital mortality was 2.9%. 11% were Stage (TNM) IA, 9.4% stage IB, 19% stage II, 24.6% stage IIIA, 13.1% stage IIIB and 23% stage IV. Five-year actuarial survival was 47.5%. Five-year survival of patients with TNM stages IA, IB, II, IIIA, IIIB and IV were 85.8%, 79.4%, 60%, 46.7% 33% and 14.3% respectively., Conclusions: Gastrectomy with D2 lymphadenectomy may be performed with low morbidity and mortality if the operation is performed in specialized centers with a strict quality control system, and without removing the pancreas during total gastrectomy unless it is suspected to be involved. This procedure could provide a good probability of long-term survival, even for patients with invaded regional lymph nodes.
- Published
- 2009
10. [Laparoscopic distal gastrectomy for gastric cancer: initial experience].
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Berrospi F, Celis J, Ruíz E, Payet E, Chávez I, and Young F
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- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Gastrectomy methods, Laparoscopy, Stomach Neoplasms surgery
- Abstract
Objective: To report the initial experience with the laparoscopy-assisted distal gastrectomy (LADG) with D2 lymphadenectomy for gastric cancer., Patients and Methods: Between May 2006 and May 2007, 29 consecutive GC patients with gastric cancer underwent LADG with D2 lymphadenectomy. The operation consisted in a laparoscopic time to perform lymphadenectomy and mobilization of the distal stomach, followed by a minilaparotomy for exteriorization of the specimen and construction of a hand sewn anastomosis., Results: Twenty-nine patients underwent LADG with D2 lymphadenectomy for gastric cancer. Mean age was 58.2 years. Mean operative time was 287.4 min. Mean number of lymph nodes resected was 42.6. Twelve patients were early gastric cancer, and seventeen were advanced gastric cancer. Mean proximal and distal resection margin were 5.8 cm and 3.5 cm, respectively. Resection margins were negative in all cases. Mean number of lymph nodes resected was 42.6. Thirty-day morbidity rate was 10.3 %. There were no postoperative deaths.CONCLUSION. The short-term results of our LADG with D2 lymphadenectomy for the treatment of gastric cancer shows that a radical surgery, in terms of resection margins and lymphadenectomy, can be done with low morbidity.
- Published
- 2008
11. [Short and long-term results of liver resection for hepatocarcinoma in Peru: a Peruvian single center experience on 232 cases].
- Author
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Ruiz E, Sanchez J, Celis J, Payet E, Berrospi F, Chavez I, and Young F
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- Adult, Aged, Aged, 80 and over, Disease-Free Survival, Female, Follow-Up Studies, Humans, Male, Middle Aged, Peru, Survival Rate, Time Factors, Carcinoma, Hepatocellular mortality, Carcinoma, Hepatocellular surgery, Hepatectomy, Liver Neoplasms mortality, Liver Neoplasms surgery
- Abstract
Background: To evaluate the short and long term outcome of liver resections for hepatocellular carcinoma a retrospective analysis was performed on 232 consecutive patients with hepatocellular carcinoma resected between January 1990 and December 2006 at the Department of Abdomen of the Instituto de Enfermedades Neoplasicas of Lima Peru., Methods: Disease-free survival (DFS) and overall survival (OS) were determined by Kaplan-Meier method, Prognostic factors were evaluated using univariate and multivariate analysis, Results: The median age was 36 years. 44.2% were associated with hepatitis B, only 16.3% had cirrhosis. The median size of the tumors was 15 cm. The median value of AFP was 5,467 ng/ml. The majority of patients underwent a major hepatectomy (74.2 % had four or more segments resected)Overall morbidity and mortality were 13.7% and 5.3% respectively. After a median follow-up of 40 months, tumour recurrence appeared in 53.3% of the patients. The 1, 3, and 5 year overall survival rates were 66.5%, 38.7% and 26.7%respectively. The 1, 3, and 5 year disease-free survival rates were 53.7%, 27.6%, and 19.9%. On multivariate analysis, presence of multiple nodules (p<0.000), cirrhosis (p=0.001), and macroscopic vascular invasion (p=0.001) were found to be independent prognostic factors related to a worse long-term survival., Conclusions: Surgical resection is the optimal therapy for large HCC and can be safely performed with a reasonable long-term survival.
- Published
- 2007
12. [Xanthogranulomatous cholecystitis: retrospective analysis of 6 cases].
- Author
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Reaño G, Sanchez J, Ruiz E, Celis J, Payet E, Berrospi F, Chavez I, Young F, and Doimi F
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- Adult, Cholecystitis diagnosis, Granuloma diagnosis, Humans, Male, Middle Aged, Retrospective Studies, Xanthomatosis diagnosis, Cholecystitis complications, Granuloma complications, Xanthomatosis complications
- Abstract
Xanthogranulomatous cholecystitis (CX) is a rare kind of chronic cholecystitis, not yet reported in our media, characterized by the presence of chronic, inflammatory infiltration, formation of granulomas, with fibrosis and severe histiocytic reaction with macrophages rich in foam cells. The object of this study is to establish the clinical, radiological and histopathological pattern of CX, by means of the analysis of 6 cases identified in a retrospective check of 191 medical histories of cholecystectomized patients suffering from anatomopathological diagnosis of chronic cholecystitis, in the Department of Abdomen of the Institute of Neoplastic Diseases, from 1939 to 2004. The clinical presentation was characterized by the presence of a palpable mass on physical examination and weight loss. There were complications in two patients. The ultrasonigraph, tomograph and/or laparotomy scans of the vesicle were similar in appearance to a locally advanced vesicular cancer. In none of the specimens was the coexistence of a vesicular carcinoma identified. The vesicle was dried out in block with adjacent hepatic parenchyma in all cases. The CX can simulate a hepatobiliary malignant neoplasia and require suitable oncological surgical treatment. In cases of vesicular tumors, which can be considered inoperable there is the possibility of being faced with a xanthogranulomatous cholecystitis (CX), a benign condition treatable with surgery.
- Published
- 2005
13. [Post-trauma ocular pain and delayed blindness in a patient living in a rural setting].
- Author
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Tena D, Carranza R, Celis J, and Núñez-Sánchez A
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- Adult, Blindness, Clostridium Infections etiology, Eye Infections, Bacterial etiology, Humans, Male, Pain, Rural Population, Clostridium Infections diagnosis, Clostridium perfringens isolation & purification, Endophthalmitis microbiology, Eye Infections, Bacterial diagnosis, Eye Injuries complications
- Published
- 2004
- Full Text
- View/download PDF
14. [Postoperative morbidity and in-hospital mortality of gastrectomy due to gastric adenocarcinoma: a report of 50 years].
- Author
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Ruiz E, Payet C, Montalbetti JA, Celis J, Payet E, Berrospi F, Chavez I, and Young F
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- Adenocarcinoma surgery, Aged, Cause of Death, Female, Humans, Male, Neoplasm Staging, Postoperative Complications, Retrospective Studies, Risk Factors, Stomach Neoplasms surgery, Treatment Outcome, Adenocarcinoma mortality, Gastrectomy mortality, Hospital Mortality trends, Stomach Neoplasms mortality
- Abstract
Objective: Determine the postoperative morbidity and in-hospital mortality of gastrectomy due to gastric cancer., Method: The study involved the review of the clinical records of all patients with histologically confirmed diagnostic of gastric adenocarcinoma, which underwent a gastrectomy at the Peruvian Institute of Neoplastic Diseases between January 1950 and December 1999. During that period, 2,033 gastrectomies were performed, 503 of which were total gastrectomies and 1,447 were distal subtotal gastrectomies. Postoperative morbidity of total and distal subtotal gastrectomy dropped from 23.7% and 14.3% during the 1950 decade, to 19.8% and 7.4% during the 1990 decade, respectively, while the in-hospital mortality of total and subtotal gastrectomy dropped from 28.9% and 19.4% during the 50s to 4.4% and 2.2% during the 90's. The most common complications were the esophagojejunal, gastrojejunal and duodenal fistulas, respiratory infections, intra-abdominal abscesses, pancreatic fistula, early intestinal obstruction, hemorrhage from the anastomosis site and surgical site infection., Results: Multivariate logistics regression analysis showed that the risk factors for in-hospital mortality of total gastrectomy were hypoalbuminemia, intraoperative blood transfusion and re-resection (OR: 2.4, 5.9 and 1.7, respectively). For distal subtotal gastrectomy, the risk factors for in-hospital mortality were hypoalbuminemia, intraoperative blood transfusion, splenectomy and re-resection (OR: 2.6, 2.46, 2.42 and 6.3, respectively)., Conclusions: Based on our results, the in-hospital mortality risk depends on the postoperative variables (hypoalbuminemia, intraoperative blood transfusion, splenectomy and re-resection) more than on the pre-operative variables, beyond the surgeon's control (age, sex, clinical stage, etc.).
- Published
- 2004
15. [Mechanical versus manual suture in the jejunal esophageal anastomosis after total gastrectomy in gastric cancer].
- Author
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Celis J, Ruiz E, Berrospi F, and Payet E
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- Anastomosis, Surgical, Female, Humans, Male, Adenocarcinoma surgery, Esophagus surgery, Gastrectomy, Jejunum surgery, Stomach Neoplasms surgery, Surgical Staplers, Suture Techniques
- Abstract
Aim: To compare the leakage rate of esophagojejunal anastomosis performed with stapler or hand sutures., Material and Methods: We studied a series of 367 patients who underwent total gastrectomy for gastric cancer at the Instituto de Enfermedades Neoplásicas (Lima-Peru) from 1986 to 1999., Results: In 197 patients esophagojejunal anastomosis was performed with stapler and in 170 with manual sutures. There were no differences between both groups with regard to age, TNM stage, operating time and hospital stay. There were 8 anastomotic leakage (4.1%) in the stapler group and 4 (2.4%) in the hand sutures group (p> 0.05). Of these 12 cases, 2 patients (16%) died of causes directly related to the leak of the esophagojejunal anastomosis., Conclusion: There were no statistical differences in the rate of leakage of the esophagojejunal anastomosis performed with stapler or hand sutures, thus both techniques should be accepted as standard procedures.
- Published
- 2001
16. [Total gastrectomy for gastric cancer in patients over 70 years old].
- Author
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Ruiz E, Quispe D, Celis J, Berrospi F, and Payet E
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- Adenocarcinoma mortality, Age Factors, Aged, Female, Humans, Male, Middle Aged, Postoperative Complications epidemiology, Stomach Neoplasms mortality, Adenocarcinoma surgery, Gastrectomy, Stomach Neoplasms surgery
- Abstract
Objective: To determine if the morbidity and postoperative mortality after a full gastrectomy for gastric cancer performed on patients of more than 70 years of age were different from those of younger patients., Material and Methods: Between 1980 and 1999, a total of 411 gastrectomies for gastric adenocarcinoma were performed at the Institute of Cancer Diseases (INEN). Of these, 87 were inpatients older than 70 years of age (elderly group) and 92 were inpatients between 50 and 59 years of age (young group). The clinical record of both groups were studied and the clinical-pathological features, morbidity and postoperative mortality, staying time in hospital and survival rate were compared., Results: There was no significant difference between the two groups regarding clinical-pathological features except in the TNM stage. In the elderly group 23.0% had stage IV and 43.5% in the young group (p=0.007). The average operating time in the elderly group was shorter than in the young group (5.5 hours versus 6.0 hours, p=0.015). The morbidity for the elderly group was 29.9% and that of the young group was 34.8%, whereas the postoperative mortality for the elderly and young groups was 4.6% and 2.2%, respectively. Pneumonia was the most frequent postoperative complication (14.8%) and the primary cause of postoperative death in the elderly group. Time in hospital and survival were similar between both groups., Conclusions: The morbidity and postoperative mortality after a full gastrectomy for cancer of the stomach in the elderly is no different from those found in younger patients.
- Published
- 2001
17. [Gastric cancer invading the muscularis propia].
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Ruiz E, Quispe D, Celis J, Berrospi F, and Payet E
- Subjects
- Adult, Aged, Aged, 80 and over, Data Interpretation, Statistical, Female, Humans, Lymphatic Metastasis, Male, Middle Aged, Neoplasm Metastasis, Pyloric Antrum pathology, Stomach Neoplasms mortality, Survival Analysis, Stomach pathology, Stomach Neoplasms pathology
- Abstract
Objective: Determine the clinical features and the survival of patients with gastric cancer invading the muscularis propia., Material and Methods: We reviewed the clinical records of the patients with gastric cancer invading the muscularis propia, that had undergone surgical treatment at the National Cancer Institute (INEN) between 1950 and 1999. We considered age, sex, location of the tumor, regional lymph node metastases (N), distant metastases (M), TNM stage and survival., Results: 202 patients had gastric cancer invading the muscularis propia, the mean age was 60.03 years, 105 (52%) were females, in 69% the neoplasm was in the antrum and in 22% in the body. We found regional lymph node metastases in 48% and distant metastases in 1%; 52.1% was in the IB TNM stage and 3.1% in the IV. The five year survival rate using Kaplan Meier was 66%, patients with N0, N1, N2 and N3 had 78%, 70%, 25% and 0% respectively.
- Published
- 2001
18. [GASTRIC CANCER IN YOUNG PATIENTS]
- Author
-
Quispe D, Ruiz E, Celis J, Berrospi F, and Payet E
- Abstract
OBJECTIVE: In order to determine a the clinicopatological features in young patients with gastric cancer and compare them with aged patients.PATIENTS AND METHODS: For this study, we selected the clinical charts from the total of patients with histological proved diagnosis of gastric adenocarcinoma admitted at the INEN between 1980 and 1996 whose age was less than 31 year (Young group, n =92). As a comparison group (Average Group) we chose of the same universe, a random sample of 184 patients between 50 to 70 years of age. Epidemiological, clinical and histological features, operability and resecability, TNM stage, type of surgery and follow-up of both groups were analyzed.RESULTS: In the Young Group in compared with Average Group, females were more frequent (73.9% vs. 50.5% p<0.001); mucocelular type (70% vs. 31.0%, p<0.001) and undifferentiated carcinoma (75% vs. 32.6%, p>0.001). The mean survival time in the Young Group was 74.9 months and in the Average Group was 36.03 months (p=0.26), there were no significant differences in the survival between resecability and sex (p=0.10 and p=0.41).CONCLUSION: The females and undifferentiated carcinoma was the most frequent features in the young patients with gastric cancer. The survival in this group is better than the average group but this was a no significant difference because the diagnosis was made in late stages.
- Published
- 2000
19. [SURGICAL TREATMENT OF THE LIVER METASTASES FROM COLORECTAL CANCER]
- Author
-
Ruiz E, Celis J, Berrospi F, and Payet E
- Abstract
OBJECTIVE: In the absence of extra hepatic disease, the hepatic resection is the treatment of choice for liver metastases from colorectal carcinoma, but a no treatment attitude or the use of chemotherapy still persists in some health centers. This study was done to evaluate the peri operative morbi-mortality and survival after resection of hepatic metastases from colorectal cancer in our institution.METHODS: Clinical, pathologic and outcome data of patients undergoing liver resection for metastatic colorectal cancer at the Instituto de Enfermedades Neoplasicas de Lima Peru between January 1986 and July 2000 was examined.RESULTS: Of 300 liver resections, 24 were performed in patients with liver metastases of colorectal cancer; 17 patients were men and 7 women, who ranged in age from 21 to 79 years ( a mean of 52.66 years), the site of primary disease was the rectum in 7 and colon in 17, 20 patients were Dukes C and 4 Dukes B.Synchronous secondary disease were found in 9 patients and metachronous lesions were found in 15 patients Forty nine metastases were resected (Mean size 4.5 cm, range 1.5 cm 24 cm)Seven patients underwent right hepatectomy, one right hepatectomy plus non anatomic wedge resection, two right trisegmentectomy, 4 left lobectomy and ten a non anatomical resection.The overall post operative morbidity was 8% and the 30 day post operative mortality rate was 0% Estimated three and five year survival rates using Kaplan-Meier method was 50 % and 20% respectively.CONCLUSION: Hepatic resection for a secondary malignant liver growth from colorectal cancer is relatively safe with low morbidity and mortality rates, an remains the only potentially curative treatment. We continue to recommend an aggressive surgical approach to hepatic metastases of colorectal origin in the abscense of extra hepatic disease.
- Published
- 2000
20. [MODIFIED TECHNIC OF THE PANCREATO YEYUNAL ANASTOMOSIS IN THE PROXIMAL PANCREATO DUODENECTOMY]
- Author
-
Celis J, Berrospi F, Ruiz E, and Payet E
- Abstract
INTRODUCTION: Dehiscence of pancreaticojejunostomy is the major complication after proximal pancreaticoduodenectomy (PDP) that may lead to other complications and eventually to death.OBJECTIVE: We present a modified dunking pancreaticojejunostomy used for reconstruction after PDP.SURGICAL TECHNIQUE: We first performed a purse-string suture around the cut end of the jejunal limb. The pancreas stump is intussuscepted 4 cm into the jejunum guided by two sutures between the pancreas and the intestine. Then the purse-string suture is tied around the pancreas stump, four interrupted anchoring sutures are added in order to avoid slippage of the jejunum out of the pancreas. External diversion of pancreatic and biliary secretions is achieved by means of a tube jejunostomy or a Kehr tube.MATERIAL AND METHODS: We prospectively studied 59 consecutive patients who underwent PDP at the Instituto de Enfermedades Neopl sicas between 1995 and 1998. This technique was used in all the patients regardless the characteristics of the pancreas.RESULTS: Only one (1.7%) patient developed a dehiscence of the pancreticojejunostomy that healed spontaneously. Post-operative morbidity and mortality rate were 35.6% and 0%, respectively.CONCLUSION: Our modified dunking pancreaticojejunostomy is simple, safe and applicable to all type of pancreas and is our standard technique of reconstruction after PD.
- Published
- 2000
21. [HEPATITIS B AND C VIRUS INFECTION AS RISK FACTORS FORHEPATOCARCINOMA IN PERU: CASE AND CONTROL STUDY]
- Author
-
Ruiz E, Almonte M MPH, Pizarro R, Celis J, Montalbelti JA, and Urbano R
- Abstract
To investigate whether past exposure to Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) were risk factors for the development of Hepatocellular Carcinoma (HCC) in Peru, a case-control study of 136 patients with HCC and 136 age-matched and sex-matched control subjects was performed. Past exposure to HBV and HCV were assessed respectively by antibody to hepatitis B core antigen (Anti-HBc) and HbsAg and anti-HCV.Of the HCC cases, 63.2% were posuitive for HbsAg and 0.73% foranti-HCV. Of the control patients, 4.4% were positive to HbsAg and 0.73% to anti-HCV.The mean age of patients with HCC negative for HbsAg was significantly greater than that of patients HCC positive for HbsAg (35.4 versus 29.4 years, p less than 0.001).The HbsAg patients are 36.26 times more prone to developing HCC than those with HbsAg negative (95% confidence interval: 15.31-90.7).Infection with HCV does not pose a risk for the development of HCC (RR 1, 95% confidence interval: 0.062-16.152).A causal relation between HBV infection in children HCC was observed. These results indicate that HbsAg carriage is a risk factor for HCC in Peru. The importance of vertical or perinatal transmission of HBV and the prophylactic role of passive immunization plus vaccination during childhood is emphasized as well as the selective vaccination of high risk groups.
- Published
- 1998
22. [Gastrointestinal hormones during minimal enteral feeding of sick premature infants].
- Author
-
Ordaz-Jiménez MR, Fernández-Celis JM, Rivera-Rosas S, Serrano-Camargo C, Ballesteros-del-Olmo JC, and Estrada-Flores JV
- Subjects
- Birth Weight, Gastric Inhibitory Polypeptide metabolism, Gastrins metabolism, Gestational Age, Humans, Infant Food, Infant, Low Birth Weight, Infant, Newborn, Infant, Premature, Diseases therapy, Motilin metabolism, Neurotensin metabolism, Parenteral Nutrition, Total, Prospective Studies, Secretory Rate, Time Factors, Enteral Nutrition, Gastrointestinal Hormones metabolism, Infant, Premature, Diseases physiopathology
- Abstract
Objective: To measure gastrointestinal hormonal response (GHR) with minimal enteral feeding (MEF) in sick premature infants., Methods: Forty-one babies birth weight < 1800 g receiving total parenteral nutrition or intravenous solutions entered the study. They were distributed in two groups: group I: 26 infants (early enteral feeding < or = 5 d) and group II = 15 infants (late enteral feeding = 10-14 d). A diluted special formula was used as MEF starting with 1 mL hourly with daily increments of 1 mL up to 120 mL. Basal and final determinations of GHR were done before and after the MEF., Results: Both groups were similar in birth weight, postnatal age, and trophism. There were intragroup differences between basal and final GHR for all hormones in both groups. Subgroups by gestational age (< or = 32 vs > 32 weeks) and trophism (< or = 1250 vs > 1250 g) also showed basal-final differences. There were no complications related to the MEF., Conclusions: MEF favors secretion of gastrointestinal hormones in sick premature infants. Early MEF seems to be preferable to late one since it allows a faster secretion related to volume of the formula. MEF did not increase abdominal complications in our infants.
- Published
- 1998
23. [OPERABILITY AND RESECTABILITY OF GASTRIC CANCER:ANALYSIS OF 2280 CASES IN 15 YEARS]
- Author
-
Ruiz E, Berrospi F, Morante C, Payet E, Celis J, and Montalbetti JA
- Abstract
OBJECTIVES: To determine which are the operability and resectability tendencies of gastric cancer in Peru.BACKGROUND: In Peru, gastric cancer is the first cause of death in men and the third one in women. Most of the patients with gastric cancer receive treatment al the Instituto Nacional de Enfermedades Neoplásicas of Lima (INEN).PATIENTS AND METHODS: Every patient with untreated histologically verified gastric adenocarcinoma, who was admitted to the INEN between January 1980, and December 1994, was included.We determined the actual trends of operability and resectability. These rates were calculated and compared with rates of the 1952-1977 period.The 1980-1994 period was divided in lustrums to evaluate a more complete preoperative staging act upon operability and resectability.The causes of inoperability and irresectability were also determined.RESULTS: Between 1980 and 1994 a total of 2280 new gastric cancer patients were admitted to the INEN. The operability and resectability rates of the 1980-1994 period (56,8% and 58,5% respectively) differ significantly from rates of the 1952-1977 period (43,8% and 49,2% respectively). A more complete preoperative staging produces a decrease of operability and an increase of resectability.The main causes of inoperability were poor physical condition associated to a locally advanced tumor 34%, and peritoneal metastases 26%. The main causes of irresectability were peritoneal metastases 50,3%, and invasion to adjacent organs 26,7%.CONCLUSIONS: Even when there is an increase of operability and resectability rates, gastric cancer is still diagnosed al a late stage in Peru. It is vital to stage pathology precisely to avoid unnecessary laparotomies.
- Published
- 1997
24. [Surgical treatment of Klatskin's tumor].
- Author
-
Ruiz E, Celis J, and Sullón J
- Subjects
- Anastomosis, Roux-en-Y, Bile Duct Neoplasms diagnostic imaging, Bile Duct Neoplasms pathology, Cholangiopancreatography, Endoscopic Retrograde, Female, Follow-Up Studies, Hepatectomy, Humans, Klatskin Tumor diagnostic imaging, Klatskin Tumor pathology, Male, Middle Aged, Time Factors, Bile Duct Neoplasms surgery, Hepatic Duct, Common pathology, Hepatic Duct, Common surgery, Klatskin Tumor surgery
- Abstract
Usually primary cancer originating in the hepatic duct confluence (Klatskin Tumor) is regarded as unresectable at diagnosis and therefore percutaneously or endoscopically placed stents have been advocated. Unfortunately with these palliative modalities the median survival is only 3-6 months. However with aggressive surgical resection of the tumor 17% of five year survival have been obtained. The present paper summarizes our experience from three patients with Klatskin tumor which underwent surgery. The Klatskin tumors were Type II (one case), Type IIIa (one case) and Type IIIb (one case). The patient with tumor Type II had wide tumor excision and extrahepatic bile duct resection at the liver hilum. The patients with tumor Type III had extrahepatic bile duct resection at the liver hilum with left and right hepatectomy respectively. Reconstruction was made with Roux-en-Y biliary enteric anastomosis, the mean post operative stay was 9 days. The mean post operative survival of two patients undergoing surgery with curative intent was 21 months, in contrast to 10 months for the patient with palliative surgery. One patient is alive 22 months with no evidence of disease. Our results supports an aggressive surgical approach in patients with Klatskin tumor which should include Hepatectomy to obtain free resection margins.
- Published
- 1995
25. [Morbidity and mortality related to gastroenteroanastomosis in advanced gastric cancer].
- Author
-
Berrospi F, Ruiz E, Morante C, Celis J, and Montalbelti JA
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Humans, Liver Neoplasms secondary, Male, Middle Aged, Palliative Care, Peritoneal Neoplasms secondary, Prognosis, Retrospective Studies, Risk Factors, Gastroenterostomy mortality, Postoperative Complications, Stomach Neoplasms surgery
- Abstract
Objective: Determination of the postoperative morbidity and mortality after gastroenterostomy in patients with unresectable gastric cancer., Study Design: Retrospective review of clinical records of all patients with obstructive distal gastric cancer who underwent gastroenterostomy at the Instituto de Enfermedades Neoplásicas between 1980 and 1993. The following factors were analyzed: age, sex, hemoglobin, albumin, preoperative risk, ascites, extent of disease, operative time, hospital stay, morbidity and mortality., Results: 198 gastroenterostomy were done with a morbidity and mortality rates of 20% and 10%, respectively. Pneumonia was the principal cause of postoperative morbidity and mortality. High operative risk, adjacent organ invasion by the tumor and peritoneal metastasis were factors associated with increased postoperative morbidity (p > 0.05). High operative risk was the only prognostic factor for postoperative mortality (p < 0.01)., Conclusions: Because of high postoperative morbidity and mortality, gastroenterostomy should not be done in patients with unresectable gastric cancer and high preoperative risk.
- Published
- 1995
26. [Combined chemotherapy with the FEM protocol in advanced gastric cancer].
- Author
-
Vallejos C, Payet C, Nuñez J, Montalbetti J, Solidoro A, Salazar F, Sánchez J, Celis J, Casanova L, and Otero J
- Subjects
- Adult, Aged, Aged, 80 and over, Epirubicin administration & dosage, Female, Fluorouracil administration & dosage, Humans, Male, Middle Aged, Mitomycin administration & dosage, Neoplasm Staging, Stomach Neoplasms pathology, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Stomach Neoplasms drug therapy
- Abstract
Thirty one patients with diagnosis of Gastric Cancer were admitted in this study. Median age was 71 years (range 24-82). Twenty two were male. No one had previous chemotherapy. Functional capacity was 0-1 in 26/31 (60.6%). More common symptoms were: loss of weight 21/31 (75.1%) and abdominal pain in 13/31 (40.3%). Ten patients were Borrmann III and nine Borrmann IV. Twenty one had surgery: 12 palliative gastrectomy and 9 exploratory laparatomy. Twenty three cases were adenocarcinoma and 8 undifferentiated carcinoma. FEM regimen was administered (5 Fluoruracil 600 mg/m2/day 1 and 8, Epidoxorubicin 30 mg/m2/day 1 and Mitomycin 10 mg/m2/day 1). Ten of 24 patients (41.7%) achieved partial remission with a median survival of 10.5 months. Three patients achieved subjective response with a median survival of 6 months. Median survival for the non response was 3 months (range 2-7 months). Survival difference between responders and no responders was statistically significant. Survival among the adjuvent group was 5.7 months (range 2-16 months). One out of three patients survived without evidence of disease at the end of this study. Twenty three patients died and 5 were lost to follow up. Alopecia was the most common secondary effect in 74%, nausea and vomiting in 60% and leukopenia below 3000 x mm3 in 54%. Cardiotoxicity was not documented in any case.
- Published
- 1989
27. [Life tables for Venezuela for the years 1974 and 1975].
- Author
-
Paez Celis J and Escalona LA
- Subjects
- Americas, Demography, Developing Countries, Latin America, Research, South America, Venezuela, Life Tables
- Published
- 1978
28. [Trial of a demographic-economic model for the description of some causes of rural-urban migration in Venezuela].
- Author
-
Laxague Ceballos G and Paez Celis J
- Subjects
- Americas, Demography, Developing Countries, Emigration and Immigration, Latin America, Population, South America, Venezuela, Population Dynamics
- Published
- 1975
29. [The mortality level of the Venezuelan population].
- Author
-
Paez Celis J
- Subjects
- Americas, Demography, Developing Countries, Latin America, Population, Population Dynamics, South America, Venezuela, Mortality
- Published
- 1976
30. [Demographic aspects of marginality in Venezuela].
- Author
-
Paez Celis J
- Subjects
- Americas, Latin America, South America, Venezuela, Developing Countries
- Published
- 1978
31. [The demographic explosion. The Venezuelan case].
- Author
-
Celis JP
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Demography, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Venezuela, Population Growth
- Published
- 1966
32. [Composition of the Venezuelan population].
- Author
-
Angulo Arvelo LA, Arévalo J, Celis JP, and León JB
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Venezuela, Population
- Published
- 1966
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