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Chapter 19 of the book "Bioinformática con Ñ" a project aiming to provide specialized educational bibliography on Bioinformatics for Spanish speakers. The result consists on more than 500 pages where the following matters are covered: biomedical databases, sequence analysis, phylogeny and evolution, structural biology, including diverse topics such as docking, virtual screening or molecular dynamics, statistics and R, systems biology, programming skills, data mining, parallel computation, bibliography management and science article writing.