21,634 results on '"Animals"'
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2. Performing Animality
- Author
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Pedro Manuel
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Performance ,Co-presence ,Non-humans ,Animals ,Real ,Dramatic representation. The theater ,PN2000-3307 - Abstract
Considering performances with animals such as Going to the Dogs (Wim T. Schippers, 1986), Octavio and I (Linda Molenaar, 2010), Performances for Pets (Juurak/ Bailey 2014) and A Performance With an Ocean View (for a Dog) (Kokkonnen, 2008), I argue that these works illustrate three emergent effects of performing with animals: challenging a binary and exclusionary view of co-presence in performance; determining a modification of the performer’s interaction with a non- human animal audience; reversing the humanization of the animal, by rehearsing an animalization of human agency.
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- 2023
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3. Multispecies Families in Latin American Law
- Author
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Marcia Condoy Truyenque
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family ,animals ,multiespecies families ,right to the free development of the personality ,Animal culture ,SF1-1100 ,Law in general. Comparative and uniform law. Jurisprudence ,K1-7720 - Abstract
A recent attitudinal change towards animals has led many people to recognize their family structures as multispecies families, that is, a family composed of human members and animals of other species, united by affective ties, and solidarity, in a horizontal relationship, and even where there is mutual recognition. This social phenomenon requires that the legal concept of family, which today more than ever accepts the plurality of family structures, also includes multispecies families. The protection of multispecies families is necessary and possible if one considers that in Latin America today, a post-positivist legal system prevails that is aimed at protecting fundamental rights and freedoms. This legal system allows for a broad interpretation of rights such as the right to free development of personality and the right to family integrity, rights that already serve as foundational for the recognition and protection of multispecies families in Latin America.
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- 2023
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4. Colistin resistance in Escherichia coli and Klebsiella pneumoniae in humans and backyard animals in Ecuador
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Carlos Bastidas-Caldes, Salomé Guerrero-Freire, Nimer Ortuño-Gutiérrez, Temmy Sunyoto, Cícero Armídio Gomes-Dias, Maria Soledad Ramírez, William Calero-Cáceres, Anthony D. Harries, Joaquín Rey, Jacobus H. de Waard, and Manuel Calvopiña
- Subjects
colistin ,escherichia coli ,klebsiella pneumoniae ,humans ,animals ,drug resistance ,genes, mdr ,operational research ,ecuador ,Medicine ,Arctic medicine. Tropical medicine ,RC955-962 ,Public aspects of medicine ,RA1-1270 - Abstract
Objective. Colistin is an antibiotic of last resort for treating serious Gram-negative bacterial infections. However, the misuse of colistin, especially as an animal growth promoter, has contributed to increasing antimicrobial resistance, mediated mainly through plasmid transfer of the mcr-1 gene. This study assessed the prevalence of phenotypic and molecular colistin resistance in Escherichia coli and Klebsiella pneumoniae in Ecuador in healthy humans and their chickens and pigs. Methods. Fecal samples were collected from humans and their chickens and pigs in two rural coastal and Amazon regions between April and August 2020. Gram-negative bacteria were isolated and identified using conventional techniques. Phenotypic resistance was determined using the broth microdilution technique, and the mcr-1 gene was detected using conventional polymerase chain reaction. Results. A total of 438 fecal samples were obtained from 137 humans, 147 pigs and 154 chickens. The prevalence of E. coli isolates was 86.3% (378/438) and K. pneumoniae, 37.4% (164/438). Overall, the mcr-1 gene was found in 90% (340/378) of E. coli isolates, with higher prevalences found in isolates from coastal regions (96.5%, 191/198), humans (95.6%, 111/116) and chickens (91.8%, 123/134); for K. pneumoniae, the gene was found in 19.5% (32/164) of isolates, with equal distribution between regions and hosts. Only four isolates, two E. coli and two K. pneumoniae, showed phenotypic resistance: mcr-1 was present in both E. coli strains but absent in the K. pneumoniae strains. Conclusions. Despite a low prevalence of phenotypic resistance to colistin, the high prevalence of the mcr-1 gene in E. coli is of concern. Ecuador’s ban on using colistin in animal husbandry must be enforced, and continual monitoring of the situation should be implemented.
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- 2023
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5. Determinación de la biodiversidad y evolución de la complejidad en la finca La Palma, municipio Perico
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Yuseika Olivera-Castro, Néstor Francisco Núñez-García, and Wendy Mercedes Ramírez-Suárez
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animals ,diversification ,plants ,sustainability ,Agriculture (General) ,S1-972 ,Animal culture ,SF1-1100 - Abstract
Objective: To characterize biodiversity and determine the evolution of complexity in La Palma farm, in the El Roque town, Perico municipality, Matanzas, Cuba. Materials and Methods: The evolution of animal and plant biodiversity was quantified in the farm. Margalef and Shannon indexes (H ́) and the degree of complexity of biodiversity, which considers five components: noxious, functional, introduced functional, auxiliary and productive, were determined during three years (2017-2019). Results: The inventory recorded several species of animals and plants in the farm. The main function of the animals was to produce milk and meat, animal traction and transport, mainly horses. Chicken and sheep are used for family food and dogs are used as pets. As for the plant component, the presence of species for human and animal feeding was analyzed, distributed in areas of multipurpose trees (fruit trees, timber and feed), staple crops and forage. According to the evaluation scale, the Shannon index (1,81-2,57), as well as the Margalef index (2,22-2,82), showed a value in the range considered as moderate. Regarding the complexity analysis, during 2017 and 2018, the farm was classified as not very complex, and evolved to moderately complex in 2019. Conclusions: The farm showed in the years of study increased biodiversity, of plants as well as animals. The evolution of the complexity of the farm, from low to moderately complex, according to the scale used, facilitated the formation of a strategic plan for the farmer to follow and be able to reverse the situation of his farm until it could be taken to the maximum scale (highly complex).
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- 2023
6. Prove di sensibilità per gli animali e la natura: le origini della 'questione caccia' nell’Italia liberale
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Giulia GUAZZALOCA
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animals ,hunting ,birds ,nature ,animal and environmental protection ,History (General) ,D1-2009 ,Modern history, 1453- ,D204-475 - Abstract
A “hunting question”, defined as the regulation of hunting and forms of wildlife protection, began to take shape in Europe in the second half of the 19th century and in Italy gave rise to a lively and interesting debate. The article illustrates its main issues and shows how the problem of hunting acted as a link between movements for animal protection and those for the protection of the environment. Moreover it sheds light on how the “hunting question” was also important for the consolidation of the first forms of sensitivity to nature and living species. In relation to Italy in the years between the 19th and 20th centuries, the article analyzes the battles of the animal protection societies against the “inhuman hunting” and the “bird massacre”, the positions and objectives of the naturalist movement, the main concrete results of these mobilizations.
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- 2022
7. Abitare la parola 'ecologia'. L’ottica postantropocentrica di Antonella Anedda
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Justyna Hanna Orzeł and Hanna Serkowska
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ecology ,animals ,plants ,things ,space ,poetry ,Romanic languages ,PC1-5498 ,Philology. Linguistics ,P1-1091 - Abstract
The article explores Antonella Anedda’s works from a post-anthropocentric perspective within the theoret-ical framework of ecocriticism. After mentioning some of the most relevant concepts and ideas connected with these lively approaches in interdisciplinary studies, it presents a brief and deliberately ongoing introduction to an outline of observations on the poet’s production, considering the key eco-categories such as animals, plants and space.
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- 2022
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8. Therapeutic Role of Animals: A Comprehensive Literature Review on the Prevalent Forms and Species in Animal-Assisted Interventions
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Dorota Szewczyk, Jakub Fiega, Milena Michalska, Urszula Żurek, Zuzanna Lubaszka, and Ewa Sikorska
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animals ,zootherapy ,felinotherapy ,therapeutic animals ,animal-assisted therapy ,the human-animal bond ,Education ,Sports ,GV557-1198.995 ,Medicine - Abstract
Animals have been valued and used to improve human physical and mental health since ancient times. Animal-assisted therapy (AAT) is a complementary approach to traditional medicine, involving trained animals. AAT can enhance cognition, commitment, character growth, and the learning process. Commonly used species in animal-assisted therapy include cats, dogs, horses, dolphins, and others. Feline-assisted therapy alleviates loneliness and stress, whereas canine-assisted therapy positively impacts emotions and overall well-being. Equine-assisted interventions benefit individuals with cognitive and motor disabilities. Dolphin-assisted therapy shows promise for conditions like autism and cerebral palsy. However, ethical concerns have arisen, particularly in children with behavioral disorders. Safety measures, adult supervision, and proper screening and hygiene practices are crucial in AAT programs. In conclusion, AAIs have a significant potential to enhance well-being and mental health across various contexts, but more research is needed to fully understand their effectiveness and safety in different settings and age groups. The existing literature consists of subjective accounts and inadequate methodologies.
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- 2023
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9. Erasing the extinct: the hunt for Caribbean monk seals and museum collection practices
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Dolly Jørgensen
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environmental history ,extinction ,museums ,natural history ,animals ,History of medicine. Medical expeditions ,R131-687 - Abstract
Abstract The Caribbean monk seal (Monachus tropicalis), the only seal species native to Central America, was declared extinct in 2008, with the last confirmed sighting in 1952. This species historically had a broad range throughout the gulf of Mexico. This article discusses the history of Western science on the monk seal, from its first recorded sighting by a Western colonizer in 1492 to scientific collection in the 1800s and 1900s, as a history of the erasure of this species. Museum practices of collecting and displaying Caribbean monk seals have directly contributed to this erasure, and ways of writing a new history by giving the Caribbean monk seal the capacity to refuse erasure are suggested.
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- 2022
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10. Wild and trapped: a history of Colombian zoos and its revelations of animal fortunes and State entanglements, 1930s-1990s
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Claudia Leal
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Colombia ,animals ,State ,history ,History of medicine. Medical expeditions ,R131-687 - Abstract
Abstract This article presents the first history of Colombian zoos and one of the few contributions to the history of these institutions in Latin America. It proposes that in this region’s zoos native animals tended to predominate, signaling the increasing transformation of forests and other native ecosystems into croplands and pasturelands, as well as the growing distance between people and natural environments. Colombian zoos additionally underscore the limitations of the State in its period of most rapid expansion. They reveal how private interests overshadowed the State by providing public amenities, but also how they offered unconventional solutions to certain hurdles of State formation.
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- 2022
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11. The politics of animal extinction and conservation: Interests, framing, and policy
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Maria Armoudian
- Subjects
animals ,animal species ,biodiversity ,conservation ,environment ,extinction ,Environmental sciences ,GE1-350 ,Political science - Abstract
Why do conservation policies fail to prevent species extinctions and die-offs in contravention of stated intentions and goals? Bringing together a range of literature, including political ecology, political theory, conservation science, communication theory and environmental communication with original data, this article explores this question, then addresses these failures within Aotearoa New Zealand's context. Using the New Zealand case, it offers a systems-level view of these failures, focusing on the influences and limitations that arise from the political-economic structures, fractured governance, interest group influence, and non-governmental organizations (NGOs) in representative democracies. Secondly, in these settings, we argue that communication and framing by the interested parties—politicians, government officials, interest groups and NGOs—buttress this system, partly by normalizing it, obscuring scientific realities, shifting focus away from deeper issues, and thus limiting the possibility of substantive solutions in what might be called a colonization of consciousness. Together, this economic-political-communication complex has failed to prevent—and in some ways aided—mass die-offs of native animal species. The article then suggests exploring alternative models, such as deliberative democracy, to this seemingly intractable problem, to strengthen the influence of scientific expertise, better inform decision-makers, advance public understandings of science, and improve democracy by engaging members of the public in decision-making processes. While this study focuses on New Zealand, the issues related to political ecology, the political-economic systems, and the framing of issues, apply to many democratic countries.
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- 2023
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12. Chaetotaxy of the fourth larval stage of Pintomyia longiflocosa, a primary vector of cutaneous leishmaniasis in Colombia.
- Author
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Méndez-Cardona S, Carrasquilla MC, González C, and Santamaría E
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- Animals, Colombia, Male, Microscopy, Electron, Scanning, Female, Sensilla ultrastructure, Larva growth & development, Larva anatomy & histology, Leishmaniasis, Cutaneous transmission, Leishmaniasis, Cutaneous parasitology, Leishmaniasis, Cutaneous epidemiology, Insect Vectors parasitology, Insect Vectors anatomy & histology
- Abstract
Introduction: Pintomyia (Pifanomyia) longiflocosa is an endemic species from Colombia, found between the central and eastern Andes, and reported as one of the primary vectors of cutaneous leishmaniasis in coffee-growing zones of the country. This species is classified in the Townsendi series and can only be identified by the morphology of the male adults., Objective: To determine the potential use of the fourth larval stage of the vector Pi. longiflocosa in morphological taxonomy based on the description of its chaetotaxy., Materials and Methods: Pintomyia longiflocosa adults were captured in Campoalegre, Huila, and reared in the Entomology Laboratory at the Colombian Instituto Nacional de Salud. To identify the setae found in each corporal segment, 15 fourth-instar larvae were mounted on microscope slides using Canadian balm after being cleared with 10 % potassium hydroxide and saturated phenol. Additionally, five specimens were prepared for their observation by scanning electron microscopy., Results: Based on the description of Pi. longiflocosa, we established that all species of the subgenus Pifanomyia so far described have the same antennal morphology and clavate setae along their body. However, various setae present in Pi. longiflocosa are absent in Pi. youngi, suggesting differences among the larvae of the Townsendi series., Conclusions: These results support the potential importance of morphological characters from the fourth larval instar, such as antennal morphology and chaetotaxy, specifically in closely related species that are cryptic in their adult stages.
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- 2024
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13. In vitro evaluation of the pathogenicity of fungi isolated from the Urabá region (Antioquia, Colombia) against Aedes aegypti larvae
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Machado-Agudelo DA, García MA, Rueda-Páramo ME, and Cardona NL
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- Animals, Colombia, Pest Control, Biological, Trichoderma pathogenicity, Trichoderma physiology, Mosquito Control methods, Mosquito Vectors microbiology, Aedes microbiology, Larva microbiology
- Abstract
Introduction. Aedes aegypti is an important vector of arboviral diseases like dengue among others. Traditional control strategies, such as the use of insecticides, have lost effectiveness due to the emergence of resistance in mosquito populations. Biological control and fungi applied for biocontrol are presented as viable and ecological alternatives. Objective. To evaluate in vitro pathogenicity of Trichoderma sp. isolates obtained from Urabá (Antioquia) on larvae of Ae. aegypti, and to determine the mean lethal concentration and mean lethal time of the most pathogenic isolate. Materials and methods. Using the sentinel larvae method of Ae. aegypti, fungi were isolated from water bodies in the Urabá region (Antioquia). The isolates were characterized morphologically and molecularly to determine their taxonomic identity. Pathogenicity tests were performed in vitro on Ae. aegypti larvae in the L2/L3 stages. Subsequently, a strain was selected to establish its mean lethal concentration and mean lethal time. Results. Trichoderma sp. strain AP-91 caused high mortality in larval populations of Ae. aegypti. We estimated a mean lethal concentration of 1.8 × 107 conidia/ml and a mean lethal time of 20.67 hours. Conclusion. The strain AP-91 showed potential for its use as biological control of Ae. aegypti, making it a suitable candidate for scale-up cultures applied to integrated vector management. This research suggests exploring compounds and enzymes produced by the AP-91 strain to understand better its pathogenicity.
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- 2024
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14. Knowledge, attitudes, and practices towards rabies: A preliminary cross-sectional appraisal in Colombia.
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Meriño-Olivella S, Sánchez-Bonilla MDP, Aguirre-Acevedo DC, and Correa-Valencia NM
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- Colombia epidemiology, Humans, Cross-Sectional Studies, Animals, Male, Female, Adult, Middle Aged, Young Adult, Surveys and Questionnaires, Adolescent, Pets, Aged, Dogs, Rabies prevention & control, Rabies epidemiology, Health Knowledge, Attitudes, Practice
- Abstract
Introduction: Rabies virus infection can cause fatal brain disease in mammals. Any species is susceptible to infection. Any effort aimed at recognizing infected animals and performing first actions in the event of transmission is mandatory., Objective: To determine knowledge, attitudes, and practice profiles regarding rabies, or hydrophobia, in a municipality of Colombia, using a multiple correspondence analysis., Materials and Methods: A descriptive observational study involving 71 pet owners was carried out in the municipality of Ibagué (Tolima). A questionnaire-based survey collected data on rabies knowledge, attitudes, practices, and demographic information. The survey was conducted between October and November 2021, and the data analysis involved descriptive statistics and multiple correspondence analysis., Results: The study revealed a commendable level of rabies awareness among the urban residents in the study municipality. However, there are causes of concern as they allow stray animals to enter their homes and are not aware of the importance of notifying dead animals. The respondents demonstrated a humane approach to bite management and emphasized the importance of wound cleaning. Additionally, they expressed a strong desire for more information to enhance their knowledge and awareness of the disease., Conclusion: The findings of this study provide valuable insights for improving rabies prevention efforts and promoting public health. Health education, evidence-based strategies, and community participation are essential for successful disease control and educational gaps addressing related to sociocultural factors.
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- 2024
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15. Right ventricular dysfunction: pathophysiology, experimental models, evaluation, and treatment.
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Real C, Pérez-García CN, Galán-Arriola C, García-Lunar I, and García-Álvarez A
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- Humans, Heart Ventricles physiopathology, Heart Ventricles diagnostic imaging, Ventricular Function, Right physiology, Animals, Disease Models, Animal, Ventricular Dysfunction, Right physiopathology, Ventricular Dysfunction, Right diagnosis, Ventricular Dysfunction, Right therapy, Ventricular Dysfunction, Right etiology
- Abstract
Interest in the right ventricle has substantially increased due to advances in knowledge of its pathophysiology and prognostic implications across a wide spectrum of diseases. However, we are still far from understanding the multiple mechanisms that influence right ventricular dysfunction, its evaluation continues to be challenging, and there is a shortage of specific treatments in most scenarios. This review article aims to update knowledge about the physiology of the right ventricle, its transition to dysfunction, diagnostic tools, and available treatments from a translational perspective., (Copyright © 2024 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
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16. Aedes aegypti feeding behavior during dengue outbreaks in two rural areas of Peru during the Yaku cyclone and El Niño phenomenon of 2023.
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Ruiz-Polo AA, Santillan-Valdivia RE, Saavedra-Rios CY, Nuñez-Rodriguez CM, and Niño-Mendoza LE
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- Animals, Peru epidemiology, El Nino-Southern Oscillation, Humans, Rural Health, Rural Population, Aedes virology, Dengue epidemiology, Dengue transmission, Disease Outbreaks, Feeding Behavior, Cyclonic Storms
- Abstract
Background: Motivation for the study. Dengue epidemics caused by A. aegypti occur during climatic events in tropical countries such as Peru; however, the feeding behavior of the mosquito usually goes unnoticed., Background: Main findings. A. aegypti populations in Marcavelica and Querecotillo showed anthropophilic feeding behavior during cyclone Yaku and in the 2023 El Niño. However, populations with different feeding patterns are not ruled out., Background: Implications. The PCR-RFLP technique of the blood cell cytochrome B gene could be implemented in vector control policies through an entomo-virological surveillance plan., Objective.: To determine the feeding behavior of Aedes aegypti in dengue outbreaks in two rural areas of Peru during the Yaku cyclone and El Niño phenomenon of 2023., Material and Methods.: Eight blood samples (8 pools) were obtained from the abdomen of 80 Aedes aegypti specimens captured in the rural districts of Querecotillo and Marcavelica during the Yaku cyclone and El Niño dengue outbreaks. DNA was extracted from the analyzed samples, then a PCR was directed at the CytB gene as a genetic marker and the PCR products were enzymatically digested with the restrictases Hae III and Mwo I. The PCR-RFLP products were visualized by agarose gel electrophoresis at 4%., Results.: DNA was obtained from all samples and a 358 bp amplicon was obtained as a PCR product. Likewise, the only RFLP found in Hae III was from Homo sapiens sapiens (233 and 125 bp). RFLP was not found in Hae III of Gallus gallus and RFLP in Mwo I of Canis familiaris and Mus musculus., Conclusion.: Aedes aegypti showed conserved anthropophilic feeding behavior in dengue outbreaks in rural areas during the Yaku cyclone and El Niño.
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- 2024
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17. Coexistence and food sources of adult mosquitoes (Diptera: Culicidae) in a rural health center in Piura, Peru 2024.
- Author
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Ruiz Polo AA, Luis Arismendiz LD, Barrera Rivera LV, Alvarado Aldana A, Saavedra Cornejo KI, and Juárez Vilchez JP
- Subjects
- Animals, Peru, Cross-Sectional Studies, Female, Male, Humans, Culicidae physiology, Feeding Behavior, Dogs, Culex, Mosquito Vectors, Rural Health, Aedes
- Abstract
Background: Motivation for the study. Rural health facilities could be potential foci of transmission and scenarios of zoonosis during epidemic outbreaks of dengue and other arbovirosis due to the coexistence of mosquito species that feed on different vertebrates., Background: Main findings. Aedes aegypti feeds on Homo sapiens sapiens. Culex quinquefasciatus feeds on Homo sapiens sapiens and Canis familiaris. Both coexist in health care areas of the Querecotillo health center., Background: Implications. Molecular techniques should be integrated into vector control to understand feeding patterns in natural conditions and information on probable reservoirs., Background: This study aimed to determine the coexistence and food sources of adult mosquitoes (Diptera: Culicidae) in a rural health center in Piura, Peru by using a descriptive cross-sectional design. Entomological techniques were used to capture and identify mosquitoes, and molecular biotechnology techniques were used to identify food sources. A total of 793 specimens of the Culex and Aedes genera were found coexisting, 789 (99.5%) were Culex quinquefasciatus, 607 (76.9%) were males and 182 (23.1%) were females. Likewise, 4 (100%) corresponded to Aedes aegypti females. The food sources of Aedes aegypti were Homo sapiens sapiens, and Homo sapiens sapiens and Canis familiaris were the food sources of Culex quinquefasciatus. This study provides evidence that rural health centers could be acting as foci of arbovirosis, with the risk that people who come for different ailments could contract diseases transmitted by C. quinquefasciatus and A. aegypti.
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- 2024
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18. Establishment of a rabbit model of different degrees of testicular torsion.
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Zhu X, Peng C, Wu Z, Zhang X, Liu S, Luo Y, and Yang L
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- Animals, Rabbits, Male, Severity of Illness Index, Testis blood supply, Testis pathology, Testis diagnostic imaging, Ultrasonography, Doppler, Color, Spermatic Cord Torsion, Disease Models, Animal, Random Allocation
- Abstract
Introduction and Objectives: Different degrees of testicular torsion result in varying degrees of testicular damage, which influences treatment options and outcomes. Therefore, establishing a testicular torsion model with different degrees is necessary for clinical diagnosis., Materials and Methods: Rabbits were randomly divided into four groups and their spermatic cords were twisted at 0 °, 180 °, 360 °, and 720 °, respectively. Color Doppler flow imaging (CDFI) were performed to evaluate the blood supply in testicles. The twisted testicles were surgically removed at six hours post-operation and were evaluated by morphological observation and Hematoxylin and Eosin staining., Results: CDFI signals were gradually decreased as the degree of testicular torsion increased, and scores of CDFI in the 360 ° and 720 ° groups were significantly decreased at postoperative six hours compared to pre-surgery. Compared to the sham, the testicle in the 180 ° group exhibited slight congestion, whereas the testicles in the 360 ° and 720 ° groups were dark red in color and had severe congestion and unrecognizable vessels. Hematoxylin and Eosin staining showed mild spermatogenic cell reduction and testicular interstitial hemorrhage in the 180 ° group. In the 360 ° and 720 ° groups, disordered seminiferous tubules, shed spermatogenic cells in tubules, inflammatory cell infiltration, and severe hemorrhage were found. In comparison with the sham, interstitial hemorrhage scores in the 360 ° and 720 ° groups were significantly higher, and scores of germinal epithelial cell thickness in the three testicular torsion groups were significantly decreased., Conclusions: Collectively, we successfully constructed a testicular torsion model with different degrees in rabbits., (Copyright © 2024 AEU. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
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19. Hypersensitivity Pneumonitis in a 5-Year-Old Girl due to Turtledove: A Case Report.
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Quentin M, Marie-Catherine R, and Floriane S
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- Child, Preschool, Female, Humans, Animals, Birds, Alveolitis, Extrinsic Allergic diagnosis
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- 2024
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20. NRF2 Signaling Pathway in Chemo/Radio/Immuno-Therapy Resistance of Lung Cancer: Looking Beyond the Tip of the Iceberg.
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Ramisetti SV, Patra T, Munirathnam V, Sainath JV, Veeraiyan D, and Namani A
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- Humans, Animals, Mice, Immunotherapy, Kelch-Like ECH-Associated Protein 1 metabolism, Chemoradiotherapy, Radiation Tolerance, Cullin Proteins genetics, NF-E2-Related Factor 2 metabolism, NF-E2-Related Factor 2 genetics, Lung Neoplasms therapy, Lung Neoplasms genetics, Lung Neoplasms metabolism, Signal Transduction, Drug Resistance, Neoplasm
- Abstract
Lung cancer is one of the most common causes of cancer death in men and women worldwide. Various combinations of surgery, chemotherapy, radiation therapy and immunotherapy are currently used to treat lung cancer. However, the prognosis remains relatively poor due to the higher frequency of tumor mutational burden (TMB). Nuclear factor E2-related factor 2 (NFE2L2/NRF2) is often considered a primary regulator of the expression of antioxidant enzymes and detoxification proteins and is involved in cytoprotection. On the contrary, NRF2 is even known to induce metastasis and support tumor progression. Kelch-like ECH-associated protein 1 (KEAP1) plays an important role in negatively regulating NRF2 activity via CUL3-mediated ubiquitinylation and successive proteasomal degradation. Extensive research has shown that the genetic alterations of KEAP1/NFE2L2/CUL3 genes lead to increased expression of NRF2 and its target genes in lung cancer. Thus, these studies provide ample evidence for the dual role of NRF2 in lung cancer. In this review, we discussed the mechanistic insights into the role of NRF2 signaling in therapy resistance by focusing on cell lines, mouse models, and translational studies in lung cancer. Finally, we highlighted the potential therapeutic strategies targeting NRF2 inhibition, followed by the discussion of biomarkers related to NRF2 activity in lung cancer. Overall, our article exclusively discusses in detail the NRF2 signaling pathway in resistance to therapy, especially immunotherapy, and its therapeutic avenue in the treatment of lung cancer., (Copyright © 2024 SEPAR. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
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21. [Paederus Dermatitis, a disease not to forget]
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Félix Caviedes C, Chamorro Gaón Y, and Freire P
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- Male, Humans, Adult, Animals, Dermatitis, Contact etiology, Pyrans, Coleoptera
- Abstract
Paederus contact dermatitis is a skin disease caused by beetles of the genus Paederus and the release of a vesicant substance called paederin. It is worldwide distributed; However, it is more common in rainy seasons and hot climates. The clinical manifestations are vesicle-pustules that settle on erythematous skin. Treatment is based on washing with soap and water to neutralize the action of the toxin and the administration of topical steroids in short cycles. We report the case of a 28-year-old male patient who came to the dermatology clinic with a 48-hour history of two erythematous plaques with central blisters plus superficial ulceration located on the flexor aspect of the arm and right forearm, accompanied by a sensation of burning and itching at the site of the lesions, without other accompanying symptoms. As background, he states that he was on vacation in the coastal region of Ecuador when the lesions appeared. An incisional biopsy was performed and due to the clinical characteristics and the history of travel to a tropical region, it was diagnosed as Paederus dermatitis and treatment with antihistamines, topical steroids and cold compresses was indicated. After 8 days of treatment, the lesions subsided, leaving post-inflammatory hyperpigmentation., (Universidad Nacional de Córdoba)
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- 2024
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22. Evaluation of nasogastric tube fixation methods: adhesion, displacement and skin integrity.
- Author
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Thorpe LIF, Silva JCD, Moraes RB, Gonçalves NDS, Alves ADN, and Santos ICRV
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- Swine, Animals, Tissue Adhesions, Humans, In Vitro Techniques, Intubation, Gastrointestinal methods, Intubation, Gastrointestinal instrumentation, Skin
- Abstract
Objective: to evaluate three methods of nasogastric tube fixation in terms of adhesion, displacement and skin integrity., Method: ex vivo study, with a sample of 30 experimental noses (10 for each type of fixation), developed with porcine skin, based on the average measurements of the human nose, in which 14-gauge polyvinyl chloride probes were inserted and 2 methods of fixation with adhesive tape (Fixation A and B) and one with an industrial device (Fixation C) were used. Each group was exposed to traction of 50, 100 and 500g sequentially over 12 and 24 hours, testing: adhesion capacity, probe displacement and skin integrity. The Chi-square test of independence was calculated for nominal variables and Student's t-tests and analysis of variance (p< 0.05) for rational variables., Results: fixation B showed lower adhesion capacity (p <0.001) when compared to the other two fixations. A mean displacement of 52.17 mm was observed in the probes fixed by methods A and B and a greater occurrence of lesions associated with fixations A and C (p = 0.001)., Conclusion: the results show complications related to the fixations: lack of adhesion, displacement of the probe and skin lesions, drawing attention to the complexity of the procedure.
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- 2024
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23. [Angelman syndrome: current approach and the future of therapies].
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Sell E and Heymans J
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- Humans, Oligonucleotides, Antisense therapeutic use, Ubiquitin-Protein Ligases genetics, Animals, Angelman Syndrome therapy, Angelman Syndrome genetics, Genetic Therapy
- Abstract
Angelman syndrome is a severe neurodevelopmental disorder secondary to disruption of the UBE3A gene in the maternal allele of chromosome 15. Its manifestations are mainly neurological, but a multidisciplinary management is required for its treatment. There are consensus guidelines available for best clinical management. Current clinical trials with antisense oligonucleotides promise, for the first time, to treat the cause by activating the UBE3A gene in the paternal allele, showing encouraging preliminary clinical effects. Inoculation of UBE3A gene through a viral vector has been tested in animal models and is underway for future clinical trials.
- Published
- 2024
24. Lysyl oxidase expression in smooth muscle cells determines the level of intima calcification in hypercholesterolemia-induced atherosclerosis.
- Author
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Ballester-Servera C, Alonso J, Taurón M, Rotllán N, Rodríguez C, and Martínez-González J
- Subjects
- Animals, Humans, Mice, Aortic Valve pathology, Aortic Valve metabolism, Male, Proprotein Convertase 9 genetics, Proprotein Convertase 9 metabolism, Mice, Transgenic, Tunica Intima pathology, Tunica Intima metabolism, Diet, Atherogenic adverse effects, Atherosclerosis pathology, Atherosclerosis genetics, Protein-Lysine 6-Oxidase metabolism, Protein-Lysine 6-Oxidase genetics, Myocytes, Smooth Muscle metabolism, Myocytes, Smooth Muscle pathology, Vascular Calcification pathology, Vascular Calcification genetics, Vascular Calcification etiology, Vascular Calcification metabolism, Disease Models, Animal, Muscle, Smooth, Vascular metabolism, Muscle, Smooth, Vascular pathology, Hypercholesterolemia complications, Mice, Inbred C57BL, Aortic Valve Stenosis pathology, Aortic Valve Stenosis metabolism, Aortic Valve Stenosis genetics
- Abstract
Introduction: Cardiovascular calcification is an important public health issue with an unmeet therapeutic need. We had previously shown that lysyl oxidase (LOX) activity critically influences vascular wall smooth muscle cells (VSMCs) and valvular interstitial cells (VICs) calcification by affecting extracellular matrix remodeling. We have delved into the participation of LOX in atherosclerosis and vascular calcification, as well as in the mineralization of the aortic valve., Methods: Immunohistochemical and expression studies were carried out in human atherosclerotic lesions and experimental models, valves from patients with aortic stenosis, VICs, and in a genetically modified mouse model that overexpresses LOX in CMLV (TgLOX
CMLV ). Hyperlipemia and atherosclerosis was induced in mice through the administration of adeno-associated viruses encoding a PCSK9 mutated form (AAV-PCSK9D374Y ) combined with an atherogenic diet., Results: LOX expression is increased in the neointimal layer of atherosclerotic lesions from human coronary arteries and in VSMC-rich regions of atheromas developed both in the brachiocephalic artery of control (C57BL/6J) animals transduced with PCSK9D374Y and in the aortic root of ApoE-/- mice. In TgLOXCMLV mice, PCSK9D374Y transduction did not significantly alter the enhanced aortic expression of genes involved in matrix remodeling, inflammation, oxidative stress and osteoblastic differentiation. Likewise, LOX transgenesis did not alter the size or lipid content of atherosclerotic lesions in the aortic arch, brachiocephalic artery and aortic root, but exacerbated calcification. Among lysyl oxidase isoenzymes, LOX is the most expressed member of this family in highly calcified human valves, colocalizing with RUNX2 in VICs. The lower calcium deposition and decreased RUNX2 levels triggered by the overexpression of the nuclear receptor NOR-1 in VICs was associated with a reduction in LOX., Conclusions: Our results show that LOX expression is increased in atherosclerotic lesions, and that overexpression of this enzyme in VSMC does not affect the size of the atheroma or its lipid content, but it does affect its degree of calcification. Further, these data suggest that the decrease in calcification driven by NOR-1 in VICs would involve a reduction in LOX. These evidences support the interest of LOX as a therapeutic target in cardiovascular calcification., (Copyright © 2024 Sociedad Española de Arteriosclerosis. Publicado por Elsevier España, S.L.U. All rights reserved.)- Published
- 2024
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25. Symbology of Animal Motifs in the Verneh Textures of Shahsevan Tribe
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Sanam Arzani and Reza Rezalou
- Subjects
shahsevan tribe ,verneh ,symbology ,animals ,Arts in general ,NX1-820 ,Medieval history ,D111-203 - Abstract
Most of the nomads of East Azerbaijan province belong to the tribes of Arasbaran and Shahsevan, nine independent tribes in the Yaylak period, and seven independent tribes in the Qishlaq period. Shahsevan nomads are composed of different tribes, such as Ajirlu, Moghanlu, Giglu, Qaralar Meshgini etc. Verneh, as a type of carpet, Maffrash or means of carrying household furniture, were mainly woven by nomads and some villagers in the settlement of Shahsevan nomads in Azerbaijan and some surrounding areas, such as Pars Abad, Germi and Meshgin Shahr counties of Ardabil province, and Ahar and Kaleybar counties of East Azerbaijan province. This handicraft has both the simplicity of the rug (Kilim) style and the elegance and beauty of the carpet. The lack of sufficient information in this field has led to a close study of some of these motifs related to Verneh. Therefore, one of the most important objectives of the research is to introduce motifs, concepts and animal symbols hidden in Verneh, in order to expand knowledge about the artistic products of this region and examine the impact of nomadic life conditions on the nature of their products in these areas. The research method is applied in terms of nature and purpose and its findings were first done as field research. Then, the samples from the studies were matched with the general information and eventually examined. The results of this study show that the animal motifs created in verneh tell the truth about the material and social life of weavers and show a valuable collection in their life. Verneh’s paintings and motifs depict the nomadic way of life, the animal-dependent life in direct connection with nature, the adherence to the customs of the ancestors and the beliefs of these people. Animal motifs are a symbol of nomadic life, related to nomadic livestock.
- Published
- 2021
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26. The vegan industrial complex: the political ecology of not eating animals
- Author
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Amy Trauger
- Subjects
ethics ,animals ,food ,environment ,political ecology ,Environmental sciences ,GE1-350 ,Political science - Abstract
Many political ecologists and geographers study ethical diets but most are curiously silent on the topic of death in the food system, specifically what or who is allowed to live and what is let die in the "doing of good." This article aims to show how the practice of eating produces the socio-ecological harm most ethical consumers set out to avoid with their dietary choices. I examine the food systems that produce ethical products for 1) the hierarchical ordering of consumer health in the Global North over the health and well-being of workers in the Global South and 2) how vegetarianism involves the implicit privileging of some animals over others. The article takes take a genealogical approach to the political ecology of food ethics using Black and Indigenous studies in conversation with animal geographies. I draw on Mbembe's (2016) necropolitics, Weheliye's (2014) "not quite human" and Lowe's (2015) critique of humanism to develop a conceptual framework for what lives or dies as a result of ethical dietary choices. I use this framework to examine commodities for the socio-ecological harm that their production extends into the world under the guise of "doing good" or "being ethical." Taking a harm reduction and food sovereignty approach, I advocate for a new ethical framework that includes a limited case for consuming animals.
- Published
- 2022
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27. Embodiment and the Animal in Guadalupe Nettel’s El matrimonio de los peces rojos
- Author
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Isabelle Wentworth
- Subjects
embodied simulation ,cognition ,animals ,posthumanism ,guadalupe nettel ,Latin America. Spanish America ,F1201-3799 ,French literature - Italian literature - Spanish literature - Portuguese literature ,PQ1-3999 - Abstract
This article explores an interaction between posthumanist and cognitive discourses through the work of award winning Mexican author, Guadalupe Nettel. I focus on her 2014 anthology, Natural Histories, rereading the central motif of the narrative, that animals ‘are like a mirror that reflects submerged emotions or behaviours that we don’t dare to see’ (Nettel, 9). This ‘reflection’ is not simply the image of the human reflected off the opaque surface of the animal, but rather the humans themselves act as a mirror, simulating the behaviour of the animals with which they cohabit. This can be read as a literary representation of a neurophysiological phenomenon — embodied simulation, an internal mimicry, either perceptible or imperceptible, performed when watching others completing certain tasks, movements or expressions (Gazzola et al. 2007; Uithol et al. 2011; Iacoboni 2009). In particular, the first story, ‘El matrimonio de los peces rojos’, depicts a profound human-nonhuman embodied resonance that moves between linguistic, narratological and characterological levels. A cognitive critical approach to the mirroring between animals and humans in the stories reveals the particular intersection between new paradigms in cognitive science, animal studies, and posthumanism that the anthology develops, each of its narratives intertwining mind, body and nonhuman other in a non-hierarchical network.
- Published
- 2021
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28. Lire les techniques pour comprendre les rapports entre humains et non-humains
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Nastassia Reyes
- Subjects
animals ,non-humans ,technique ,fishing ,local knowledge ,ethnoecology ,Anthropology ,GN1-890 - Abstract
The ethnoecological approach provides a complex framework to address the relationship between humans and the environment. It opens the way to a detailed understanding of the practices, uses and representations of the actors. This reveals how the different elements of a technical tool, in fishing for case in point, are related to the characteristics and behaviours of the target animal. Rather than an analysis based essentially on the material dimension, this proposal insists on the changeable and seasonal dimension of practices, and on the understanding acquired by the fisherman about the fish. I intend to follow, as a reflexive chronicle, the conceptual and methodological process undertaken during the surveys conducted among artisan fishermen in the northern Mediterranean area. A focus will be placed on the environmental practices and knowledge of the fishermen of Catania (Sicily). I will discuss in detail the contributions and limitations that I was confronted with throughout the data collection work, and I will make proposals for an analysis of the knowledge and practices that is devoid of the incompleteness inherent in the understanding of environmental knowledge. On the one hand, this proposal aims to report on the techniques with a level of finesse that makes sense for the fishermen, and on the other hand, on the intimate links between human and non-human actors - in this case the fisherman and the fish - in the fishing practice.
- Published
- 2022
29. Medieval Naturalia
- Author
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Chantal Stein
- Subjects
Naturalia ,Exotica ,Animals ,Unicorn ,Treasuries ,History (General) ,D1-2009 ,Medieval history ,D111-203 - Abstract
The nascent global age at the close of the Middle Ages introduced exotic objects from distant lands into Western Europe. Exotica from the natural world – naturalia – were frequently fashioned into ecclesiastical and seigniorial artifacts and housed in treasuries. The materials were sometimes re-identified in their new contexts, such as narwhal tusks understood as unicorn horns, which bestowed upon them additional meanings associated with those allegorical mythical creatures. This work investigates the movement, alteration, and use of such re-identified naturalia in late medieval society leading up to the Age of Discovery. It focuses on naturalia that retained their distinct morphological features after working, following the hypothesis that the identity of the animal, as indexed by a recognizable form or set of physical characteristics, was important. It additionally considers symbolic connotations and occult properties deriving from allegorization of matter to study the role played by the ornamentation of naturalia. This paper explores the discourse between extant tangible objects and contemporary texts such as bestiaries, lapidaries, and alchemical compendia to examine how the iconography of the artifact’s form and the iconology of the ornamentation contributed to the overall signification of the naturalia.
- Published
- 2021
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30. Sporotrichosis transmitted by domestic cats: A case report.
- Author
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Iacovone Basílico ML, Mantero MN, Caristia L, Della Giovanna P, and Alfaro CT
- Subjects
- Cats, Female, Animals, Adolescent, Humans, Cat Diseases microbiology, Cat Diseases diagnosis, Cat Diseases transmission, Sporotrichosis diagnosis, Sporotrichosis transmission, Sporotrichosis drug therapy
- Abstract
Sporotrichosis is a subacute to chronic subcutaneous mycosis caused by dimorphic fungi of the Sporothrix spp. complex. It is considered the most frequent subcutaneous mycosis in Latin America and predominates in tropical areas. In Argentina, its prevalence is estimated at 0.01-0.02%. In half of the patients, it manifests as lymphocutaneous sporotrichosis. Infection results from the agent's inoculation on the skin or mucous membrane by trauma with contaminated plants. There are also cases of zoonotic transmission by contact with animals, such as armadillos, birds, rats, horses, fish, mosquitoes, and cats. Here we describe the case of a 14-year-old female patient who consulted due to nodular lymphangitic syndrome for two months and, given the lack of response to multiple antibiotic regimens, a biopsy was performed and a culture of the lesion was done, which confirmed the diagnosis of lymphocutaneous sporotrichosis., (Sociedad Argentina de Pediatría.)
- Published
- 2024
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31. The Representation of Jonathan Swift’s Human and Non-human Animals in Spain
- Author
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Alberto Lázaro-Lafuente
- Subjects
jonathan swift ,gulliver’s travels ,ecocriticism ,animals ,censorship. ,History of Great Britain ,DA1-995 ,Language and Literature - Abstract
Gulliver’s Travels (1726), by Jonathan Swift, is one of the classics of English literature, a biting satire of English customs and politics in particular and of human foibles in general. While literary scholars have traditionally agreed that, in Part IV of Gulliver’s Travels, Swift uses his elegant anthropomorphic horses and his filthy human-like Yahoos to reflect on society and human nature, some recent studies highlight Swift’s ecocritical concern with animal issues, focusing on how the behaviour of the noble horses challenges the conventional hierarchies of the anthropocentric view of the world and anticipates values that are prominent in today’s society. However, this article aims to show that what has traditionally challenged and disturbed readers, publishers and critics for many years is the presence of the other race of the animal world, the Yahoos. Analysing the reception of Gulliver’s journey to the land of the Houyhnhnms helps understand how Swift’s early ecocritical ideas disturbed publishers and translators, who often rejected or modified the text, particularly those passages in which the filthy human-like Yahoos show their harsh and scatological behaviour.
- Published
- 2020
32. Influence of different local anesthetics on atracurium neuromuscular blockade on rats
- Author
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João Paulo Soares da Silva Trizotti, Angélica de Fátima de Assunção Braga, Vanessa Henriques Carvalho, and Franklin Sarmento da Silva Braga
- Subjects
Local anesthetics ,Lidocaine ,Racemic bupivacaine ,Nondepolarizing neuromuscular blocking drugs ,Atracurium ,Animals ,Rats ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Introduction: The association between local anesthetics (LA) and neuromuscular blocking (NMB) drugs in clinical practice, and the possibility of interaction between these drugs has been investigated. LAs act on neuromuscular transmission in a dose-dependent manner and may potentiate the effects of NMB drugs. Objective: The aim of this study was to evaluate, in an experimental model, the effect of lidocaine and racemic bupivacaine on neuromuscular transmission and the influence on neuromuscular blockade produced by atracurium. Methods: Male Wistar rats, weighing from 250 to 300 g were used. The preparation was set up based on a technique proposed by Bülbring. Groups were formed (n = 5) according to the drug studied: lidocaine 20 µg.mL−1 (Group I); racemic bupivacaine 5 µg.mL−1 (Group II); atracurium 20 µg.mL−1 (Group III); atracurium 20 µg.mL−1 in a preparation previously exposed to lidocaine 20 µg.mL−1 and racemic bupivacaine 5 µg.mL−1, Groups IV and V, respectively. The following parameters were assessed: 1) Amplitude of hemi diaphragmatic response to indirect stimulation before and 60 minutes after addition of the drugs; 2) Membrane potentials (MP) and miniature endplate potentials (MEPPs). Results: Lidocaine and racemic bupivacaine alone did not alter the amplitude of muscle response. With previous use of lidocaine and racemic bupivacaine, the neuromuscular blockade (%) induced by atracurium was 86.66 ± 12.48 and 100, respectively, with a significant difference (p = 0.003), in comparison to the blockade produced by atracurium alone (55.7 ± 11.22). These drugs did not alter membrane potential. Lidocaine initially increased the frequency of MEPPs, followed by blockade. With the use of bupivacaine, the blockade was progressive. Conclusions: Lidocaine and racemic bupivacaine had a presynaptic effect expressed by alterations in MEPPs, which may explain the interaction and potentiation of NMB produced by atracurium.
- Published
- 2020
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33. The Animal Clue to In-signifying Power: the Case of El Eternauta
- Author
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Valeria Wagner
- Subjects
great divides ,el eternauta ,insignificance ,animals ,karl marx ,History of Portugal ,DP501-900.22 ,History of Spain ,DP1-402 ,Latin America. Spanish America ,F1201-3799 ,French literature - Italian literature - Spanish literature - Portuguese literature ,PQ1-3999 ,Social Sciences - Abstract
This paper focuses on tangential figurations of the “animal question”. Starting from the difficulty to avoid reproducing the Great Divides that Donna Haraway observes in many theorists in the field of animal studies, and from Cornelius Castoriadis’ analysis of the institution and reproduction of power divisions, I follow the animal trail in some of Marx’s methodological reflexions and in the science fiction Argentinian comic El Eternauta (1957-59) by Héctor G. Oesterheld and Solano López.
- Published
- 2020
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34. Who Looks at? A Course with Animals
- Author
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Sergio Chejfec
- Subjects
animals ,gaze ,literature ,photographs ,videos ,History of Portugal ,DP501-900.22 ,History of Spain ,DP1-402 ,Latin America. Spanish America ,F1201-3799 ,French literature - Italian literature - Spanish literature - Portuguese literature ,PQ1-3999 ,Social Sciences - Abstract
Two semesters ago I proposed a course around texts of different genres and moments, with the condition that they include representations of the animal, or directly animals. Each year the course is dedicated to literary forms and techniques. The fact that the readings refer to animals could be interpreted as a whim. But I do not think whims are irrelevant. Probably it happens the other way around: whim, curiosity, zigzagging exploration could be stimulating reading acts tin order to question installed premises which in literature are frequent, largely because they are easily adopted. And yet, it was not a whim; it was an invitation to perform a test, imprecise in its results, as I will explain
- Published
- 2020
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35. First identification of Angiostrongylus spp. in Lissachatina fulica and Cornu aspersum in Antioquia, Colombia
- Author
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Gamarra-Rueda R, García R, Restrepo-Rodas DC, and Pérez-García J
- Subjects
- Animals, Colombia epidemiology, Cross-Sectional Studies, Prospective Studies, Humans, Angiostrongylus isolation & purification, Snails parasitology, Strongylida Infections epidemiology, Strongylida Infections parasitology, Strongylida Infections veterinary
- Abstract
Introduction: Abdominal and neural angiostrongyliasis caused by Angiostrongylus costaricensis and A. cantonensis, respectively, are zoonotic diseases involving snails as intermediate hosts. Colombia has already reported human cases, and the increasing distribution of Lissachatina fulica and Cornu aspersum raises public health concerns due to the potential risk of disease transmission in areas where parasites and hosts coexist., Objective: To identify the presence of Angiostrongylus spp. in snail species L. fulica and C. aspersum in Antioquia, Colombia., Materials and Methods: This prospective cross-sectional study had a population of 5,855 L. fulica and C. aspersum snails captured in the ten towns of the Valle de Aburrá (Antioquia, Colombia), 169 samples were collected in 28 sampling points. Lung tissues of the collected snails were dissected and analyzed to detect Angiostrongylus spp. through molecular techniques., Results: Angiostrongylus spp. were identified in both L. fulica and C. aspersum. Angiostrongylus costaricensis was detected in 18 pooled prevalence of 30% (95% CI = 19.2-43.3), and Medellín was the municipality with the highest number of positive samples (33.3%). Seventy-two-point-two percent of the positive places reported the presence of rodents. None of the tests were positive for A. cantonensis., Conclusion: Our findings provide important insights into the epidemiology and distribution of Angiostrongylus spp. in Antioquia, Colombia. The identification of these parasitic nematodes in L. fulica and C. aspersum highlights the potential role of these snails as intermediate hosts in the transmission of Angiostrongylus spp. infections in the Valle de Aburrá, with implications for human and veterinary health.
- Published
- 2024
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36. Trypanosoma spp. infection in urban and wild ecotopes of the caribbean region in Colombia.
- Author
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Benavides-Céspedes I, Ardila MM, Jiménez-Cotes G, Avendaño-Maldonado L, Lozano-Arias D, Garcia-Alzate R, and Herrera L
- Subjects
- Animals, Colombia epidemiology, Male, Female, Urban Health, Trypanosomiasis epidemiology, Trypanosomiasis transmission, Trypanosomiasis veterinary, Caribbean Region epidemiology, Chiroptera parasitology, Trypanosoma classification, Trypanosoma isolation & purification
- Abstract
Motivation for the study. The role of bats as hosts of Trypanosoma spp. in the Atlantic department in Colombia, as well as its taxonomic diversity has been poorly studied. Main findings. This is the first report of frequency of infection by Trypanosoma spp. in bats in the Atlántico Department in Colombia. Implications. The great adaptive capacity of bats to different ecological niches and its role as hosts of Trypanosoma spp. for wild and urban ecotopes represents a risk factor in transmission cycles of epidemiological importance. We conducted a study to evaluate the frequency of infection by Trypanosoma spp. in bats captured in wild and urban ecotopes in the Department of Atlántico in the Caribbean region of Colombia from March 2021 to May 2022. Bats were taxonomically identified, and sex, relative age, and reproductive conditions were determined. A blood sample was used for parasitological analysis and DNA extraction to amplify a region of the 18S rRNA. 125 bats were collected, with the most abundant families being Molossidae (62/125; 49.6%) and Phyllostomidae (43/125; 34.4%). Molossus molossus collected in wild habitats showed an infection frequency of 8.1% (5/61) and 4.1% (3/61) through parasitological and molecular analysis, respectively. In comparison, Noctilio albiventris collected in urban habitats showed an infection frequency of 16.6% (2/12) for both analyses. These findings represent the first records of M. molossus harboring trypanosomes for the Department of Atlántico and of N. albiventris harboring trypanosomes in Colombia.
- Published
- 2024
- Full Text
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37. Carbapenems and colistin resistance genes isolated in Musca domestica from a garbage dump near a hospital in Lima.
- Author
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Alarcón-Calle MA, Osorio-Guevara VL, Salas-Asencios R, Yareta J, Marcos-Carbajal P, and Rodrigo-Rojas ME
- Subjects
- Animals, Peru, Hospitals, Microbial Sensitivity Tests, Genes, Bacterial, Colistin pharmacology, Houseflies genetics, Houseflies microbiology, Carbapenems pharmacology, Anti-Bacterial Agents pharmacology, Drug Resistance, Bacterial genetics
- Abstract
Motivation for the study. The presence of antibiotic resistance genes in bacteria isolated from common flies is a potential public health hazard because it facilitates the presence and spread of antibiotic resistance genes in the environment. Main findings. Thirty-eight bacterial strains identified in 14 species were isolated from within the fly bodies, of which 31 strains showed resistance to carbapenems and 26 strains showed resistance to colistin. Seven bacterial strains showed carbapenem resistance genes and one Escherichia coli strain had resistance to KPC, OXA-48 and mcr-1. Implications. This is the first report of antibiotic resistance genes in bacteria carried by common flies in Peru. The objective was to determine the presence of carbapenem resistance genes and plasmid resistance to colistin (mcr-1) in bacteria isolated from Musca domestica in a garbage dump near a hospital in Lima, Peru. Bacteria with phenotypic resistance to carbapenemics were isolated on CHROMagar mSuperCARBATM medium and colistin resistance profiling was performed using the colistin disk elution method. Detection of blaKPC, blaNDM, blaIMP, blaOXA-48, blaVIM and mcr-1 genes was performed by conventional PCR. The antimicrobial susceptibility profile was determined using the automated MicroScan system. We found that 31/38 strains had phenotypic resistance to carbapenemics and 26/38 strains had phenotypic resistance to colistin with a minimum inhibitory concentration ≥ 4 µg/ml. Finally, we identified seven bacterial strains with carbapenem resistance genes (OXA-48 and KPC) and one bacterial strain with plasmid resistance to colistin (mcr-1). One Escherichia coli strain had three resistance genes: KPC, OXA-48 and mcr-1.
- Published
- 2024
- Full Text
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38. Fortified milk: a rare cause of intestinal obstruction in pre-term patients.
- Author
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Ramírez Díaz R, Ibarra Rodríguez I, Gavilanes Salazar GM, Moreno Hurtado C, and Chamorro Juárez MR
- Subjects
- Humans, Female, Infant, Newborn, Animals, Food, Fortified, Infant, Premature, Diseases etiology, Diagnosis, Differential, Intestinal Obstruction etiology, Intestinal Obstruction surgery, Milk adverse effects, Infant, Premature
- Abstract
Introduction: Intestinal obstruction secondary to the use of fortified milk is a rare cause in pre-term patients., Case Report: We present the case of a female pre-term newborn admitted as a result of abdominal distension and rectal bleeding, which mimicked necrotizing enterocolitis. On abdominal X-ray, she had an obstruction pattern, and on ultrasonography, echogenic masses at the distal ileum were observed. Given the lack of improvement with conservative management, urgent exploratory laparotomy was decided upon. At surgery, compact milk masses at the level of the distal ileum were identified as the cause of intestinal obstruction. Appendicostomy and lavage with saline solution through the ileocecal valve were performed. This allowed milk masses to come out towards the colon, and a great amount of acholic stools to be expelled., Conclusion: The increase in "milk curd syndrome" cases should lead us to consider this cause in the differential diagnosis of intestinal obstruction in pre-term newborns fed with fortified milk.
- Published
- 2024
- Full Text
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39. [Deficiency in N-acetylglucosamine transport affects the sporulation process and increases the hemolytic activity of the S-layer protein in Lysinibacillus sphaericus ASB13052].
- Author
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Tarsitano J, Bockor SS, Palomino MM, Fina Martin J, Ruzal SM, and Allievi MC
- Subjects
- Hemolysis drug effects, Animals, Bacterial Proteins genetics, Bacterial Proteins metabolism, Biological Transport, Bacillaceae genetics, Bacillaceae metabolism, Acetylglucosamine metabolism, Spores, Bacterial drug effects, Spores, Bacterial growth & development, Membrane Glycoproteins genetics, Membrane Glycoproteins metabolism
- Abstract
Lysinibacillus sphaericus is a bacterium that, along with Bacillus thuringiensis var. israelensis, is considered the best biological insecticide for controlling mosquito larvae and an eco-friendly alternative to chemical insecticides. It depends on peptidic molecules such as N-acetylglucosamine to obtain carbon sources and possesses a phosphotransferase system (PTS) for their incorporation. Some strains carry S-layer proteins, whose involvement in metal retention and larvicidal activity against disease-carrying mosquitoes has been demonstrated. Alterations in the amino sugar incorporation system could affect the protein profile and functionality. Strain ASB13052 and the isogenic mutant in the ptsH gene, which is predominant in the PTS signaling pathway, were used in this study. For the first time, the presence of N-glycosylated S-layer proteins was confirmed in both strains, with a variation in their molecular weight pattern depending on the growth phase. In the exponential phase, an S-layer protein greater than 130 kDa was found in the ptsH mutant, which was absent in the wild-type strain. The mutant strain exhibited altered and incomplete low quality sporulation processes. Hemolysis analysis, associated with larvicidal activity, showed that the ptsH mutant has higher lytic efficiency, correlating with the high molecular weight protein. The results allow us to propose the potential effects that arise as a result of the absence of amino sugar transport on hemolytic activity, S-layer isoforms, and the role of N-acetylglucosamine in larvicidal activity., (Copyright © 2024 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
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40. [First autochthonous case of spotted fever associated with the Reserva Ecológica Costanera Sur, Buenos Aires City].
- Author
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Monroig J, de Seta M, Carranza J, Giamperetti S, Deodato B, Armitano R, Díaz Pérez P, de Salvo MN, Leonardo Cicuttin G, and Lloveras S
- Subjects
- Argentina, Animals, Humans, Male, Female, Rhipicephalus sanguineus microbiology, Spotted Fever Group Rickettsiosis epidemiology, Spotted Fever Group Rickettsiosis diagnosis, Ixodes microbiology, Ixodidae microbiology, Amblyomma microbiology
- Abstract
The first autochthonous case of rickettsiosis is reported here. The case occurred in the Costanera Sur Ecological Reserve, a protected area of the City of Buenos Aires, in August 2022, where 4 species of ticks were found, namely Amblyomma aureolatum, Ixodes auritulus sensu lato, Rhipicephalus sanguineus sensu stricto and Amblyomma triste. The epidemiological, ecological, clinical and laboratory aspects that allowed timely diagnosis and appropriate treatment are also described., (Copyright © 2024 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
41. [Characterization of a microbial community isolated from honey bee colonies].
- Author
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Vega MF, Libonatti C, Ramos OY, and Basualdo M
- Subjects
- Animals, Bees microbiology, Microbiota, Argentina, Gastrointestinal Microbiome, Freeze Drying, Bifidobacterium isolation & purification, Bifidobacterium genetics
- Abstract
The microbial communities within honey bee colonies contribute to the defense against pathogens. The goal of this study was to isolate, identify, and lyophilize lactic acid bacteria and bifidobacteria from the gut of nurse bees and bee bread in Apis mellifera colonies. Bacterial cultures from the intestinal content were conducted, and subsequently identified, sequenced, and lyophilized. Cross-antagonism among them was also assessed. Studies based on 16 S rRNA gene Sanger sequencing revealed that the MC3 strain had 100% identity with Bifidobacterium choladohabitans, the PP2B strain showed 99.16% similarity with Enterococcus faecium, while the PP1 strain exhibited 99.49% similarity with Lacticaseibacillus sp. and the PP1B strain showed 99.32% similarity with Lacticaseibacillus sp. There was no evidence of cross-antagonism among the strains, and the lyophilization process showed good stability and conservation. This is the first report of the isolation of B. choladohabitans from honey bee gut in Argentina, and also associates the presence of E. faecium with bee bread., (Copyright © 2024 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
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42. Heritable pulmonary arterial hypertension in rats with spontaneous systemic hypertension.
- Author
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Roldán Gómez FJ, Aranda Fraustro A, Gómez Soto L, Pulido Zamudio T, Sánchez Mendoza A, and Barbosa Carreño JA
- Subjects
- Animals, Rats, Male, Hypertension physiopathology, Hypertension complications, Hypertension genetics, Pulmonary Arterial Hypertension physiopathology, Pulmonary Arterial Hypertension genetics, Pulmonary Arterial Hypertension etiology, Disease Models, Animal
- Published
- 2024
- Full Text
- View/download PDF
43. [Chronic urticaria as an atypical reaction after a vespid bite].
- Author
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Andrade-Garbán P, González-Labrador MLA, Goyanes-Malumbres M, Brandoni-Petrone M, and Alfaya-Arias T
- Subjects
- Female, Middle Aged, Humans, Animals, Wasp Venoms adverse effects, Wasp Venoms immunology, Wasps, Urticaria etiology, Insect Bites and Stings complications, Chronic Urticaria etiology, Chronic Urticaria drug therapy
- Abstract
Background: Hymenoptera stings can produce IgE-mediated reactions, toxic reactions, or atypical reactions, which are rare. Cold urticaria has been described among the cutaneous manifestations in the atypical ones, but there is only one case of chronic urticaria., Case Report: A 56-year-old female patient experienced palmoplantar pruritus and generalized urticaria 60 minutes after two vespid stings, requiring medical assistance and several cycles of home treatment with oral antihistamines and corticosteroids for resolution in 12 weeks. Allergological studies showed normal tryptase and primary sensitization to Polistes dominula venom. Given the patient's profession, venom immunotherapy was started with Polistes dominula 100% without recurrence of urticaria after its administration., Conclusions: We present a case of IgE-mediated systemic reaction followed by self-limited chronic urticaria, related chronologically to the same vespid sting trigger.
- Published
- 2024
- Full Text
- View/download PDF
44. [Primary immune thrombocytopenia linked to the ingestion of guinea pigs (Cavia porcellus) causality or coincidence?]
- Author
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Chiang Wong H, González Guzmán MDC, and González Saldaña P
- Subjects
- Animals, Guinea Pigs, Humans, Ecuador, Lupus Erythematosus, Systemic complications, Purpura, Thrombocytopenic, Idiopathic etiology
- Abstract
The guinea pig in Ecuador is synonymous with our ancestral gastronomy and cultural tradition, but because of the diet rich in L-canavanine (alfalfa) that they receive; could limit its consumption in patients with primary immune thrombocytopenia (ITP). Ingestion of alfalfa in humans can cause kidney failure and lupus-like syndrome. The John Hopkins Lupus Center recommends avoiding it in the diet of patients with Systemic Lupus Erythematosus (SLE), as it aggravates inflammation by stimulating immune activity (flares). We present two cases of patients with ITP linked to guinea pig ingestion. It is probable, (Universidad Nacional de Córdoba)
- Published
- 2024
- Full Text
- View/download PDF
45. [Rabies: Epidemiological update and pre- and post-exposure management].
- Author
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Arsuaga M, de Miguel Buckley R, and Díaz-Menéndez M
- Subjects
- Humans, Animals, Pre-Exposure Prophylaxis, Global Health, Incidence, Rabies epidemiology, Rabies prevention & control, Rabies therapy, Rabies Vaccines administration & dosage, Post-Exposure Prophylaxis
- Abstract
Rabies is a deadly neurotropic viral infection but is preventable through vaccination. Its impact on human and animal health is often devastating. Despite advances in research and control of this disease, along with an effective vaccine, rabies continues to be a lingering threat in many parts of the world. Its high incidence reinforces the constant need to address it with scientific and public health measures. In this review article, we will explore the most important characteristics of the disease, its distribution, symptoms, prevention methods, and the global efforts that have been made to eradicate this deadly disease. The most recent research and advancements in the field of rabies will also be discussed in an effort to understand and combat this deadly disease more effectively., (Copyright © 2024 Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
46. [Septic arthritis due to Pasteurella multocida].
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Piña Delgado C, Carmona Tello MN, Bolaños Rivero M, Lavilla Salgado MC, and de Miguel Martínez I
- Subjects
- Animals, Humans, Male, Anti-Bacterial Agents therapeutic use, Middle Aged, Arthritis, Infectious microbiology, Arthritis, Infectious drug therapy, Pasteurella Infections drug therapy, Pasteurella Infections microbiology, Pasteurella multocida
- Published
- 2024
- Full Text
- View/download PDF
47. Paiches, huanganas e isangos. Repensar el antropoceno a través de la literatura oral y escrita amazónica peruana
- Author
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Stefano Pau
- Subjects
Paiche ,Calvo de Araújo ,anthropocene ,Peruvian Amazon ,animals ,ecocriticism ,Language and Literature ,Literature (General) ,PN1-6790 - Abstract
RESUMEN: Tomando como punto de partida las reflexiones de estudiosos como Philippe Descola o Boaventura de Sousa Santos sobre la necesidad de repensar las relaciones entre humanos y no-humanos, con el fin de buscar alternativas al proceso autodestructivo conocido con el controvertido nombre de Antropoceno, parece oportuno dirigir la mirada hacia la selva amazónica. En efecto, el espacio amazónico es “altamente transformacional” (Rivière) y se vive en él una frecuente inestabilidad ontológica que difumina las fronteras entre las especies. Las narraciones de las vivencias de los animales, por ejemplo, no son usadas solo como simbolización de algún antagonismo o desequilibrio social, sino que son frecuentemente percibidas como realidades. En el artículo, enmarcado en el ámbito de los estudios ecocríticos, se creará un diálogo entre algunos relatos orales –cuyos protagonistas son animales– y la novela del pintor y escritor peruano César Calvo de Araújo titulada Paiche (1963), nombre que es, además, el de uno de los mayores peces de los ríos amazónicos. A través de estas creaciones de literatura oral y escrita se reflexionará sobre el tema de los desequilibrios sociales y de la conciencia de clase como medio para repensar cómo habitar la Tierra. ABSTRACT: Taking as a starting point the considerations of scholars such as Philippe Descola and Boaventura de Sousa Santos on the need to rethink the relations between humans and non-humans in order to seek alternatives to the self-destructive process known by the controversial label of the Anthropocene, it seems appropriate to look at the Amazon rainforest. Indeed, the Amazonian space is “highly transformational” (Rivière), and there is a frequent ontological instability that blurs the boundaries between species. Narratives of animal experiences, for example, are not only used as a symbolisation of some antagonism or social inequality, but are often perceived as realities. In this article, framed in the field of ecocritical studies, a dialogue will be created between some oral stories whose protagonists are animals and the novel by the Peruvian painter and writer César Calvo de Araújo entitled Paiche (1963), which is also the name of one of the largest fish in the Amazonian rivers. Through these creations of oral and written literature, we will reflect on the theme of social inequalities and class consciousness as a means of rethinking how to inhabit the Earth.
- Published
- 2021
- Full Text
- View/download PDF
48. Beastly Modernisms: The Question of Animal Speech and Psychology in James Joyce and Virginia Woolf
- Author
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Annalisa Federici
- Subjects
James Joyce ,Virginia Woolf ,posthumanism ,animals ,language ,psychology ,Language and Literature ,Literature (General) ,PN1-6790 - Abstract
This essay analyses the ways in which James Joyce and Virginia Woolf addressed from a very early stage key issues related to contemporary posthumanist theories such as the question of animal speech and psychology. Both Joyce’s description of human-animal encounters in Ulysses and Woolf’s depiction of a sentient animal subject in Flush: A Biography at first present, and then subvert, the idea of the use of language as evidence of a human surpassing of the animal. By challenging preconceived notions of species distinctions, these authors ultimately decenter the human to focus instead on the centrality of animal subjectivity and sensory experience. While the question of a sharp divide between human and nonhuman animals along the axis of speech can be traceable to the anthropocentric tradition of western humanism and not least to such a possible source as Cervantes (whose novella “The Dialogue of the Dogs” is listed as part of both Joyce’s Trieste library and the library of Leonard and Virginia Woolf), the idea of expanding the typically modernist focus on inner life by also including other forms of subjectivity may have derived from the coeval, burgeoning fields of zoology, ethology and comparative psychology. Drawing from these sources and popular areas of knowledge which formed part of the cultural climate of the time, both Joyce and Woolf explore cross-species intersubjectivity in ways that shift the terms of representation away from anthropocentric views in order to affirm, blur and deny the boundaries between the human and the non-human.
- Published
- 2021
- Full Text
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49. Discursive networks: animals, countryside, scholar Mathematics and methodological contributions to network analysis
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Vanessa Franco Neto and Angela Maria Guida
- Subjects
animals ,countryside ,scholar mathematics ,network analysis ,Special aspects of education ,LC8-6691 ,Theory and practice of education ,LB5-3640 ,Mathematics ,QA1-939 - Abstract
This paper investigates ten mathematics textbooks distributed between the years of 2013 to 2018 in countryside schools in Brazil within the scope of the Textbook National Program in its version for the Countryside, the PNLD Campo. The analyzes take the Animal Studies as a motto to discuss the subjectivities produced in this context. The Foucaultian theorizations are adopted to examine the discursive networks described and inquired from the use of two qualitative and quantitative analysis software, Atlas TI and Gephi. The articulation of the theorization employed with the software is supported by the analysis of the Connected Concept Analysis. The results show that the animals are positioned in these materials sometimes take them as a pedagogical device, in order to capture students' attention and engagement in their teaching and learning processes in school Mathematics, while at other times they are engaged in a process of exploration of their lives to sustain a rationality that distributes, organizes, and maintains policies of life and death.
- Published
- 2019
- Full Text
- View/download PDF
50. A Group of Reliefs from the Mramba Village (the Republic of Abkhazia): To the Question of Dating
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Ekaterina Yu. Endoltseva
- Subjects
reliefs ,animals ,architectural decoration ,abkhazia ,zoomorphic ,Arts in general ,NX1-820 ,Medieval history ,D111-203 - Abstract
Article deals with a group of reliefs from the church in Mramba village. Their were dated by the paleochristian period. New findings of the last ten years permit to adjust this version. They can be now referred to the Medieval period (10 – 11 century).
- Published
- 2019
- Full Text
- View/download PDF
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