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1. [Analysis of tablets containing the antihistamine loratadine: a contribution to the identification of impurities].

Author

Issa N and Mlynárová M

Subjects
Chromatography, Thin Layer, Drug Contamination, Histamine H1 Antagonists, Non-Sedating analysis, Loratadine analysis, Tablets chemistry
Abstract

Thin-layer chromatography on silica gel (Merck) was employed to examine potential impurities present in loratadine-containing tablets. A method usable for testing of impurities was elaborated, which suitably supplements the determination of loratadine content using the spectrophotometric method in the UV region. The method was validated for selected pharmaceuticals.

Published
2004

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