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In a group of 11 sport horses, the effect of the traianig process, inclunding training and resting periods, on the metabolic profile. Training proces was divided into four part: I. End of the sport season, II. End of the resting period, III. End of the quantitative training charged and IV. End of the qualitative training charged. The level glucose in the blood serum of the observed horses was stated within the reference limits, with the tendency towards the inncreased values in the 2-st and 4-st period (4,34 – 5,03 mmol.l-1). The average values global lipid and cholesterol was stated whitin the reference limits.

Etological and physiological tests were realized on 48 horses. There were observed following activities: spontaneous kinetic activity, voice display; the elimination behavior (excretion and urination) and motionless standing. The horses were observed in 40 minute periods during the morning hours. The horses were classed into the following groups: EHB+ - crossing more than 220 sq. per 40 min. (high sensitiveness to stress), EHB+/- - crossing 131 - 220 sq. per 40 min. (mean sensitiveness to stress), EHB- - crossing 130 and less sq. per 40 min. (low sensitiveness to stress). After the evaluating of mineral, energetic, lipid, nitrogen, and enzymatic profile of sport horses there were not observed significant differences from the reference values.

Essential tremor (ET), the most common form of pathological tremor, aff ects up to 4% of the population. Accord ing to the traditional concept, ET is a monosymp tomatic benign clinical entity where tremor is associated with longevity and positive family history. Despite the high prevalence and suspected genetic component, research failed so far to fi nd a causative gene mutation for ET. The main reason is probably related to an imperfectly bounded nosological concept. There are still uncertainties around clinical defi nition of ET, which does not include isolated head tremor, voice tremor or task-specifi c tremors that often overlap with dystonic tremor. Moreover, numerous studies have shown the incidence of parkinsonism, cerebellar signs and cognitive disorders in ET. Age of onset turns out as a key factor, characterized by two peaks in the adolescence and in the old age. The classical concept of ET corresponds to early onset dis ease characterized by a positive family history, more benign progression, and relief after alcohol. Conversely, so called aging-related tremor is usually characterized by late-onset, sporadic occurrence, rapid progression, and also by cognitive dysfunction and other symp toms and signs suggestive of neurodegenerative disorder. Thus, rather than a monosymp tomatic nosological entity, ET appears as a group of dis eases featur ing action tremor. Besides unclear etiology, the possible contribution of neurodegenerative processes remains an open question in the pathogenesis of ET. Thereafter, a thorough description of the individual phenotype along with the methods of genome-wide association studies can contribute to fi nd ing causal gene polymorphisms in ET and to elucidate the pathogenesis of various forms of the dis ease. [ABSTRACT FROM AUTHOR]