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Objective: To study the experience of a comprehensive diagnosis of cervical intraepithelial neoplasia (CIN) based on the results of the first pilot visual screening in the Republic of Tajikistan. Methods: The first pilot visual screening in two large districts of the Republic of Tajikistan was carried out in 2016. A total of 68,391 women of the target groups took part in this study, of which 26,691 (39%) were from the Kushoniyon district and 41,700 (61%) from the B. Gafurov district. According to the algorithm of organized visual screening, extended colposcopy, cytological examination, and biopsy with histological examination were performed. Results: According to the results of the tests performed, in 164 cases (0.24%) CIN was diagnosed, while in 20 cases (0.03%) cervical cancer (CC) was detected (p

Objective: To assess the clinical results of cervical intraepithelial neoplasia (CIN) treatment following the outcomes of the first pilot implementation of visual screening in the Republic of Tajikistan. Methods: The study was conducted from 2016 to 2020. The piloting included the population of two large districts of Kushoniyon and B. Gafurov, with a total number of 608,700 people, which is 6.74% of the country's total population. The target group of this screening included healthy women aged 30-49 years, numbering 72574 people. As a result of communication campaigns with the target group of both districts, 69391 women participated in visual screening; the overall screening coverage was 94.2%. Of the 2958 women referred for diagnosis, in 164 cases (0.24%) CIN was identified and morphologically confirmed. Results: Tajikistan, along with piloting imaging screening, has adopted a "detection-diagnosis-treatment" strategy, which involves treatment after histological confirmation of CIN. Additionally, electrosurgical loop excision/conization was adopted as the primary method, regardless of the degree of CIN involvement. Patients with CIN in 136 (82.9%) cases underwent electrosurgical loop excision, in 21 cases – conization (12.8%), and in 7 (4.3%) cases, at the insistence of the women themselves – hysterectomy. In the long-term follow-up period from 6 months to 2 years, in 159 (96.9%) cases, a favorable course of CIN was noted after the above procedures, and in 5 (3.1%) cases, relapse occurred. Patients with relapses received re-surgical treatment using electrosurgical excision/conization with a satisfactory outcome. Conclusion: The "detection-diagnosis-treatment" strategy adopted by Tajikistan has shown its high efficiency in detecting precancerous pathology and the success of CIN treatment by electrosurgical excision/conization, which contributes to the healing of the population from precancerous pathology.

Topicality. Analysis of specialized scientific and methodological literature, generalization of the experience of leading specialists and own pedagogical observations allow stating that the state of human posture is one of the characteristics of physical development. Notably, the number of students with different musculoskeletal disorders and disharmonious physical development is increasing. Accordingly, the effectiveness of the process of physical education in the context of the modern educational institution should be associated with the use of modern technologies that allow to adequately measure and assess the state of the biogeometric profile of students' posture. Research objectives. To analyze the scientific and methodological literature with regard to the study and determination of the level of the physical condition of students of music specialties and to assess the state of posture of students of specialty "Music". Research results. The results of the study contain summarized data on the assessment of students’ physical condition, which is used in the process of physical education. Based on the study of the data of specialized scientific-methodological literature and own research, the study presents the material for assessing the level of the state of the biogeometric profile of posture of students of specialty "Music". Conclusions. The study has revealed that due to prolonged forced posture and low motor activity students of specialty “Music” experience disorders of the musculoskeletal system. The research highlights the dynamics of disorders of the biogeometric profile of the students of specialty "Music" in terms of their age. Prospects for further research will be related to the definition of directions and tasks for improving the organizational and methodological conditions for the implementation of the process of physical education of students of specialty "Music".