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8 results on '"Vlasova, V. V."'

1. Technological diversity and access of Russian regional enterprises to advanced manufacturing technologies

Author

Brilliantova, V. V., Vlasova, V. V., and Fursov, K. S.

Subjects
INNOVATION POTENTIAL OF REGIONS, КЛАССИФИКАЦИЯ РЕГИОНОВ РОССИИ, ПЕРЕДОВЫЕ ПРОИЗВОДСТВЕННЫЕ ТЕХНОЛОГИИ, СТРАТЕГИЧЕСКАЯ КОНКУРЕНТОСПОСОБНОСТЬ, ECONOMIC DIVERSIFICATION, ТЕХНОЛОГИЧЕСКОЕ РАЗНООБРАЗИЕ, COMPARATIVE ANALYSIS, ИННОВАЦИОННЫЙ ПОТЕНЦИАЛ РЕГИОНОВ, СРАВНИТЕЛЬНЫЙ АНАЛИЗ, CLASSIFICATION OF RUSSIAN REGIONS, REGIONAL ECONOMIC DEVELOPMENT, ЭКОНОМИЧЕСКАЯ ДИВЕРСИФИКАЦИЯ, РЕГИОНАЛЬНАЯ ПОЛИТИКА, REGIONAL POLICY, TECHNOLOGICAL SELF-RELIANCE, STRATEGIC COMPETITIVENESS, TECHNOLOGICAL DIVERSITY, ЭКОНОМИЧЕСКОЕ РАЗВИТИЕ РЕГИОНОВ, ADVANCED MANUFACTURING TECHNOLOGIES, ТЕХНОЛОГИЧЕСКАЯ САМООБЕСПЕЧЕННОСТЬ
Abstract

Формирование технологической базы производства и ее систематическое обновление являются важнейшими факторами укрепления конкурентоспособности компаний и одним из ключевых условий устойчивого экономического роста. Вместе с тем распространение в российских регионах передовых производственных решений, определяющих эффективность использования имеющейся ресурсной базы, происходит неравномерно. В работе рассматривается разнообразие паттернов использования передовых производственных технологий в группах регионов, которые выделяются на основе применения синтетической классификации, учитывающей базовые параметры экономического развития - структуру производства и занятости и размер подушевого ВРП с поправкой на ценовой фактор. Проанализирована взаимосвязь социально-экономических условий развития территорий и их технологических портфелей. Для достижения этой цели построены и проинтерпретированы индексы технологического разнообразия и самообеспеченности. Исследование выполнено с использованием данных федерального статистического наблюдения за разработкой и использованием ППТ за 2011-2018 гг. Проведенный анализ показал, что самостоятельная разработка технологий не является приоритетной стратегией для большинства регионов страны. Более того, все типы регионов (за исключением части аграрных) демонстрируют приоритетный характер импорта технологий. Постепенно растет спрос на результаты российских разработок, что повышает возможность выхода на рынок технологий научных и образовательных организаций высшего образования при условии формирования устойчивых механизмов трансфера знаний в реальный сектор экономики. Успешные примеры демонстрируют группы развитых регионов с опорой на добывающую и обрабатывающую промышленность и регионы, где есть субъекты-лидеры, обеспечивающие необходимую связку между научной и производственной составляющими. Развитие исследований в данном направлении может включать верификацию полученных результатов посредством использования классификаций регионов, сформированных по иным принципам, нежели близость социально-экономических условий. The development and renewal of production technologies are among the key factors determining the competitiveness and sustainable economic growth of companies. At the same time, the spread of advanced manufacturing technologies (AMT), influencing the effectiveness of resource potential, is uneven across Russian regions. The paper focuses on the diverse application patterns of advanced manufacturing technologies in the groups of regions, classified depending on key parameters of their economic development, i.e., the structure of production and employment as well as gross regional product (GRP) per capita adjusted for price factor. To examine the relationship between socio-economic parameters of regional development and technological portfolios of local enterprises, we analysed the indices of technological diversity and self- reliance of enterprises. For that purpose, we used the data from the national statistical survey on the development and use of AMT by enterprises for 20112018. The conducted analysis indicates that independent technology development is not a priority for most Russian regions. Moreover, all types of regions (except for some agricultural ones) demonstrate the priority of technology imports. However, the demand for national R&D results is gradually growing and increases opportunities for research and educational institutions to enter the technology market, provided there are sustainable mechanisms for transferring the knowledge to the real economy. Successful examples include the developed regions relying on the extractive and manufacturing industries as well as the areas where leading entities managed to link scientific and industrial components. Future studies can focus on testing the obtained results using classifications based on principles other than the similarity of socio-economic conditions of regions. Статья подготовлена в рамках научно-исследовательской работы по теме: «Исследование подходов к формированию статистических индикаторов состояния и динамики развития сферы науки и технологий», выполненной НИУ ВШЭ в 2019 г. (Государственный контракт № 0373100029519000093 от 09 сентября 2019 г.). The paper was written in the scope of research on the topic “Approaches to building statistical indicators of current state and dynamics of scientific and technological development” conducted by the HSE in 2019 (state contract No 0373100029519000093 from 09.09.2019).

Published
2020

2. [Organization dietological help for population in clinics and hospitals institution Saint-Petersburg].

Author

Dotsenko VA, Vlasova VV, Mosiĭchuk LV, and Smirnova EN

Subjects
Hospitals, Public standards, Humans, Russia, Diet Therapy, Hospitals, Public legislation & jurisprudence, Hospitals, Public organization & administration
Abstract

Experience of dietological help for population in Saint-Petersburg has shown in this article. Efficiency of dietological help in clinics and hospitals depends on completeness of investigation of fundamental bases of patient's nutrition.

Published
2009

4. [The evaluation of the palatine tonsil function in patients with chronic tonsillitis].

Author

Khmel'nitskaia NM, Vlasova VV, and Kosenko VA

Subjects
Adolescent, Adult, Child, Child, Preschool, Chronic Disease, Female, Humans, Infant, Infant, Newborn, Lymphocytes metabolism, Male, Middle Aged, Palatine Tonsil metabolism, Palatine Tonsil pathology, Tonsillitis metabolism, Tonsillitis pathology, Palatine Tonsil physiopathology, Tonsillitis physiopathology
Abstract

The authors review the results of the research performed in patients with chronic tonsillitis in 1997-1999. Immunological activity of their palatine tonsils was evaluated according to the original technique which demonstrated relations between external functional activity of the palatine tonsils and age as well as symptoms of chronic tonsillitis. Additional information is presented on interrelations between lymphocytopoietic production of the palatine tonsils and hormonal status, metabolism, ecological and physical factors. The study of lifetime activity of the palatine tonsils is necessary for examination of local immunity of the mucous membranes of the lymphoid pharyngeal ring.

Published
2000

5. [Metabolism and the functional activity of the thyroid in patients with chronic tonsillitis and excess body weight].

Author

Vlasova VV, Lantsov AA, and Khmel'nitskaia NM

Subjects
Adult, Anthropometry, Biomarkers blood, Chronic Disease, Female, Humans, Nutritional Status, Obesity physiopathology, Thyroxine blood, Tonsillitis physiopathology, Triiodothyronine blood, Obesity blood, Thyroid Gland physiopathology, Tonsillitis blood
Abstract

Clinical and laboratory tests were conducted in 138 females of reproductive age with chronic decompensated tonsillitis (CDT) with normal and excessive body mass. Improper diet of the obese patients was responsible for specific manifestations of CDT, disturbances of lipid, carbohydrate and mineral metabolism, thyroid function.

Published
1998

6. [Dirithromycin, a new antibiotic in the treatment of pharyngeal inflammation].

Author

Riazantsev SV, Kosenko VA, Vlasova VV, and Volkova VV

Subjects
Acute Disease, Adolescent, Adult, Anti-Bacterial Agents pharmacology, Drug Resistance, Microbial, Erythromycin analogs & derivatives, Erythromycin pharmacology, Erythromycin therapeutic use, Humans, Macrolides, Middle Aged, Tonsillitis drug therapy, Anti-Bacterial Agents therapeutic use, Pharyngitis drug therapy, Streptococcal Infections drug therapy, Streptococcus pyogenes drug effects
Abstract

The trial of a new antibiotic dirithromycin against acute pharyngitis and tonsillitis for safety and efficacy included 28 patients with acute tonsillitis and pharyngitis. Microbiological, biochemical, clinical and laboratory tests were conducted throughout the treatment and 2-3 weeks after the end of dirithromycin administration. The results support dirithromycin clinical potential in acute, chronic pharyngeal inflammation due to its high selective activity in relation to beta-hemolytic streptococcus A and the absence of side effects.

Published
1995

7. [Suppression of transcription of influenza virus RNA by oligonucleotide derivatives].

Author

Ledovskikh NB, Iurchenko LV, Nevinskiĭ GA, Frolova EI, Ivanova EM, Koshkin AA, Bulichev NA, Zarytova VF, and Vlasova VV

Subjects
Animals, Autoradiography, Base Sequence, Cells, Cultured, Chick Embryo, Genes, Viral, Molecular Sequence Data, Oligonucleotides chemistry, RNA, Viral drug effects, Viral Proteins metabolism, Influenza A virus genetics, Oligonucleotides pharmacology, RNA, Viral genetics, Transcription, Genetic drug effects
Abstract

The inhibitory effects of oligonucleotide derivatives on the transcription of virus RNA in an in vitro system and synthesis of virus proteins was studied. Oligonucleotide derivatives d(T)3, d(T)4, d(T)8, d(T)10, d(CCAAACA), d(TCACCCTC), d(TTCCCATT), d(AATACTCT) and d(TGACCCTCTTCCCATT), that bear residues of ethidium, deuteroporphyrin and its complexes with Fe3+, hemin, cholesterol, deuterocholesterol, estrone and naphthoquinone at the 5'-end phosphate and/or at the 3'-end phosphate were studied. Unmodified oligonucleotides and their derivatives had a negligible effect on the synthesis of cellular proteins, but did inhibit the synthesis of influenza virus proteins. The majority of structural modifications increased the inhibitory effect of oligonucleotides. It was shown that the oligonucleotide derivatives carrying residues of porphyrin, quinone, ethidium, cholesterol, deuterotestosterone and estrone at concentrations near 10 mM inhibit virus development to 50-80%. A clear inhibitory effect (20-25%) of deuteroporphyrin, cholesterol and ethidium derivatives was revealed even at concentration 0.1 mM. The obtained results testified that the inhibition of influenza virus development is dependent on the interaction of oligonucleotide derivatives with the transcription complex proteins.

Published
1992

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